CN-121978151-A - Medical instrument department room acceptance method and system

CN121978151ACN 121978151 ACN121978151 ACN 121978151ACN-121978151-A

Abstract

The disclosure provides a room acceptance method and system for medical instruments and departments, which can be applied to the technical fields of nuclear magnetic resonance and environmental monitoring. The method comprises the steps of injecting a nuclear magnetic resonance gas probe into a space to be evaluated by using a gas probe injector to form environmental disturbance of the nuclear magnetic resonance gas probe and the space to be evaluated, conducting nuclear magnetic resonance data acquisition on the space to be evaluated by using a first nuclear magnetic resonance system arranged in the space to be evaluated to obtain nuclear magnetic resonance spectrum sequences of all space units, conducting nuclear magnetic resonance diffusion weighted data acquisition on the space to be evaluated by using a second nuclear magnetic resonance system arranged in the space to be evaluated to obtain diffusion weighted imaging sequences of all space units in the space to be evaluated, and conducting environmental state evaluation on the space to be evaluated by using a processor based on the nuclear magnetic resonance spectrum sequences of all space units in the space to be evaluated and the diffusion weighted imaging sequences of all space units in the space to be evaluated to obtain evaluation results.

Inventors

CHEN YUJUN
JIN DONG
YANG DONG
TONG GUIXIAN
WANG TAO
JIANG JING
LIU NING
FANG KUN
ZHOU XIAOQIANG

Assignees

安徽省立医院(中国科学技术大学附属第一医院)

Dates

Publication Date: 20260505
Application Date: 20260209

Claims (10)

1. A medical instrument department room acceptance method, the method comprising: injecting a nuclear magnetic resonance gas probe into a space to be evaluated by using a gas probe injector to form environmental disturbance between the nuclear magnetic resonance gas probe and the space to be evaluated, wherein the space to be evaluated comprises a department room for storing medical instruments; Acquiring nuclear magnetic resonance data of the space to be evaluated by using a first nuclear magnetic resonance system arranged in the space to be evaluated to obtain a nuclear magnetic resonance spectrum sequence of each space unit in the space to be evaluated, wherein the space to be evaluated is divided into a plurality of space units, the nuclear magnetic resonance spectrum sequence of the space units comprises a plurality of nuclear magnetic resonance spectrum data which are ordered according to acquisition time, and the nuclear magnetic resonance spectrum data are used for representing interaction between the space units and the environmental gas of the nuclear magnetic resonance gas probe; Acquiring diffusion weighted data of nuclear magnetic resonance in the space to be evaluated by using a second nuclear magnetic resonance system arranged in the space to be evaluated to obtain diffusion weighted imaging sequences of each space unit in the space to be evaluated, wherein the diffusion weighted imaging sequences of the space units comprise a plurality of diffusion weighted imaging ordered according to acquisition time, and the diffusion weighted imaging is used for representing the gas diffusion state of the nuclear magnetic resonance gas probe in the space unit And carrying out environmental state evaluation on the space to be evaluated by using a processor based on the nuclear magnetic resonance spectrum sequence of each space unit in the space to be evaluated and the diffusion weighted imaging sequence of each space unit in the space to be evaluated to obtain an evaluation result.
2. The method of claim 1, wherein the spatial units are determined by dividing the space to be evaluated into a plurality of the spatial units according to a preset resolution by the first nuclear magnetic resonance system or the second nuclear magnetic resonance system using a three-dimensional spatial coding technique; The nuclear magnetic resonance data acquisition is performed on the space to be evaluated by using a first nuclear magnetic resonance system arranged in the space to be evaluated to obtain a nuclear magnetic resonance spectrum sequence of each space unit in the space to be evaluated, including: operating the first nuclear magnetic resonance system to excite the nuclear magnetic resonance gas probe to drive the nuclear magnetic resonance gas probe to interact with the ambient gas; Continuously collecting interaction conditions among gases in each space unit in the space to be evaluated according to each space unit to obtain nuclear magnetic resonance spectrum data of each of a plurality of collecting moments, and And sequencing the plurality of nuclear magnetic resonance spectrum data according to the acquisition time to obtain a nuclear magnetic resonance spectrum sequence of the space unit.
3. The method of claim 1, wherein performing nmr diffusion weighted data acquisition on the space under evaluation using a second nmr system disposed within the space under evaluation to obtain a diffusion weighted imaging sequence of spatial units in the space under evaluation, comprising: For each of the spatial units in question, Configuring regulation parameters of the second nuclear magnetic resonance system according to a first preset parameter value, and respectively exciting nuclear magnetic resonance gas probes in the space unit by using the second nuclear magnetic resonance system to obtain a plurality of first nuclear magnetic signals at the acquisition time; configuring regulation parameters of the second nuclear magnetic resonance system according to second preset parameter values, and respectively exciting nuclear magnetic resonance gas probes in the space unit by using the second nuclear magnetic resonance system to obtain a plurality of second nuclear magnetic signals at the acquisition time; determining a respective gas diffusion state at each of the acquisition times based on the respective first and second nuclear magnetic signals at each of the acquisition times, and And sequencing the gas diffusion states according to the acquisition time to obtain a diffusion weighted imaging sequence of the space unit.
4. The method of claim 1, wherein the performing, with the processor, the environmental state evaluation on the space to be evaluated based on the nmr spectrum sequence of each spatial unit in the space to be evaluated and the diffusion weighted imaging sequence of each spatial unit in the space to be evaluated to obtain an evaluation result, includes: Determining, with the processor, a sequence of chemical shifts of the nuclear magnetic resonance gas probe based on a sequence of nuclear magnetic resonance spectra of the respective spatial units, wherein the sequence of chemical shifts comprises a plurality of chemical shifts ordered by the acquisition time, each chemical shift at the acquisition time being determined from a shift between a nuclear magnetic resonance frequency shown by the nuclear magnetic resonance spectrum at the acquisition time and a reference nuclear magnetic resonance frequency of the nuclear magnetic resonance gas probe, and And obtaining the evaluation result based on the chemical shift sequence and the diffusion weighted imaging sequence.
5. The method of claim 4, wherein said determining a chemical shift sequence of said nuclear magnetic resonance gas probe based on a nuclear magnetic resonance spectrum sequence of each of said spatial units comprises: for each of said acquisition instants, According to the nuclear magnetic resonance spectrum sequence, determining nuclear magnetic resonance frequency at the acquisition moment; Determining the relative displacement between the nuclear magnetic resonance frequency and the reference nuclear magnetic resonance frequency as the chemical displacement, and And sequencing the chemical shifts according to the acquisition time to obtain the chemical shift sequence.
6. The method of claim 4, wherein the deriving the evaluation result based on the chemical shift sequence and the diffusion weighted imaging sequence comprises: For each of the spatial units in question, Determining a physical property of a constituent component in the spatial unit based on the chemical shift sequence; Determining geometric features of constituent components in the spatial unit based on the diffusion weighted imaging sequence; determining a sub-evaluation result of the spatial unit based on the physical property and the geometric feature; And obtaining an evaluation result based on the identification information of each of the plurality of space units, the mapping relation between the identification information and the sequence and the sub-evaluation result of each of the plurality of space units, wherein the mapping relation between the identification information and the sequence comprises the mapping relation between the identification information of each of the plurality of space units and the plurality of chemical shift sequences, and the mapping relation between the identification information of each of the plurality of space units and the plurality of diffusion weighted imaging sequences.
7. The method of claim 6, wherein the determining physical properties of the constituent components in the spatial unit based on the chemical shift sequence comprises: Respectively determining displacement conditions of nuclear magnetic resonance frequencies respectively represented by chemical displacements of the nuclear magnetic resonance gas probe at each acquisition time, wherein the displacement conditions comprise offset, peak number and peak value of nuclear magnetic resonance; Determining a chemical composition of the spatial unit based on the offset; determining a number of independent environments in the spatial unit based on the number of peaks; Determining the capacity of each of the independent environments for the nuclear magnetic resonance gas probe based on the peak value of each peak, and The physical properties of the constituent components in the space unit are determined based on the chemical composition, the number of independent environments, and the containment capacity of each independent environment for the nuclear magnetic resonance gas probe.
8. The method of claim 6, wherein the determining geometrical features of constituent components in the spatial unit based on the diffusion weighted imaging sequence comprises: determining a diffusion rate of the nuclear magnetic resonance gas probe within the spatial unit based on the diffusion weighted imaging sequence; determining the tortuosity degree and the communication condition of the space unit based on the standard diffusion rate and the diffusion rate of the nuclear magnetic resonance gas probe; The geometric feature is determined based on the tortuosity and connectivity.
9. The method of claim 1, wherein the injecting a nuclear magnetic resonance gas probe into the space to be evaluated to form an environmental disturbance of the nuclear magnetic resonance gas probe and the space to be evaluated comprises: Setting at least one injection point on the boundary of the space to be evaluated, and Injecting the nuclear magnetic resonance gas probe into the space to be evaluated from at least one injection point according to a preset injection mode; In the case that the boundary comprises one injection point, the preset injection mode comprises at least one of pulse injection and steady injection; And under the condition that the boundary comprises a plurality of injection points, the preset injection mode is multi-point synchronous injection.
10. A medical instrument department room acceptance system, wherein the system comprises a gas probe injector, a first nuclear magnetic resonance system, a second nuclear magnetic resonance system and a processor; The gas probe injector is configured to inject a nuclear magnetic resonance gas probe into a space to be assessed, so as to form environmental disturbance of the nuclear magnetic resonance gas probe and the space to be assessed, wherein the space to be assessed comprises a department room for storing medical instruments; the first nuclear magnetic resonance system is configured to acquire nuclear magnetic resonance data of the space to be evaluated to obtain a nuclear magnetic resonance spectrum sequence of each space unit in the space to be evaluated, wherein the space to be evaluated is divided into a plurality of space units, the nuclear magnetic resonance spectrum sequence of the space units comprises a plurality of nuclear magnetic resonance spectrum data ordered according to acquisition time, and the nuclear magnetic resonance spectrum data is used for representing interaction between the space units and environmental gas of the nuclear magnetic resonance gas probe; The second nuclear magnetic resonance system is configured to acquire nuclear magnetic resonance diffusion weighted data of the space to be evaluated, so as to obtain a diffusion weighted imaging sequence of each space unit in the space to be evaluated, wherein the diffusion weighted imaging sequence of each space unit comprises a plurality of diffusion weighted imaging ordered according to acquisition time, and the diffusion weighted imaging is used for representing the gas diffusion state of the nuclear magnetic resonance gas probe in the space unit; The processor is in communication connection with the first nuclear magnetic resonance system and the second nuclear magnetic resonance system, and is configured to receive the nuclear magnetic resonance spectrum sequence of each space unit in the space to be evaluated, which is sent by the first nuclear magnetic resonance system, and the diffusion weighted imaging sequence of each space unit in the space to be evaluated, which is sent by the second nuclear magnetic resonance system, and perform environmental state evaluation on the space to be evaluated based on the nuclear magnetic resonance spectrum sequence of each space unit in the space to be evaluated and the diffusion weighted imaging sequence of each space unit in the space to be evaluated, so as to obtain an evaluation result.

Description

Medical instrument department room acceptance method and system Technical Field The disclosure relates to the technical field of nuclear magnetic resonance and environmental monitoring, in particular to a room acceptance method and system for medical instruments. Background The air cleanliness and surface cleanliness levels of critical areas such as operating rooms, clean rooms, etc. of hospitals are directly related to medical quality, and thus environmental assessment of the critical areas is required. In the related art, environmental assessment is usually realized by using a sedimentation fungus method and the like, but the method depends on the sampling and the culture of strains, so that real-time assessment is difficult to realize, and the assessment efficiency is poor. Disclosure of Invention In view of the foregoing, the present disclosure provides a medical instrument department room acceptance method and system. According to a first aspect of the present disclosure, there is provided a medical instrument department room acceptance method, including injecting a nuclear magnetic resonance gas probe into a space to be evaluated using a gas probe injector to form an environmental disturbance of the nuclear magnetic resonance gas probe and the space to be evaluated, the space to be evaluated including a department room in which medical instruments are stored; the method comprises the steps of acquiring nuclear magnetic resonance data of a space to be evaluated by using a first nuclear magnetic resonance system arranged in the space to be evaluated, obtaining a nuclear magnetic resonance spectrum sequence of each space unit in the space to be evaluated, dividing the space to be evaluated into a plurality of space units, wherein the nuclear magnetic resonance spectrum sequence of each space unit comprises a plurality of nuclear magnetic resonance spectrum data ordered according to acquisition time, the nuclear magnetic resonance spectrum data are used for representing interaction between the space units and the environmental gas of a nuclear magnetic resonance gas probe, acquiring nuclear magnetic resonance diffusion weighted data of each space unit in the space to be evaluated by using a second nuclear magnetic resonance system arranged in the space to be evaluated, obtaining a diffusion weighted imaging sequence of each space unit in the space to be evaluated, the diffusion weighted imaging sequence of each space unit comprises a plurality of diffusion weighted imaging ordered according to acquisition time, the diffusion weighted imaging is used for representing gas diffusion states of the nuclear magnetic resonance gas probe in the space units, and evaluating the environmental states of each space unit in the space to be evaluated by using a processor, so as to obtain evaluation results. According to the embodiment of the disclosure, the space units are determined by dividing a space to be evaluated into a plurality of space units according to a preset resolution through a first nuclear magnetic resonance system or a second nuclear magnetic resonance system by utilizing a three-dimensional space coding technology, acquiring nuclear magnetic resonance data of the space to be evaluated through the first nuclear magnetic resonance system arranged in the space to be evaluated to obtain a nuclear magnetic resonance spectrum sequence of each space unit in the space to be evaluated, and the nuclear magnetic resonance spectrum sequence comprises the steps of operating the first nuclear magnetic resonance system, exciting a nuclear magnetic resonance gas probe to drive the nuclear magnetic resonance gas probe to interact with environmental gas, continuously acquiring interaction conditions among gases in each space unit in the space to be evaluated for each space unit to obtain nuclear magnetic resonance spectrum data of each of a plurality of acquisition moments, and sequencing the nuclear magnetic resonance spectrum data according to the acquisition moments to obtain the nuclear magnetic resonance spectrum sequence of the space unit. According to the embodiment of the disclosure, nuclear magnetic resonance diffusion weighted data acquisition is performed on a space to be evaluated by using a second nuclear magnetic resonance system arranged in the space to be evaluated to obtain a diffusion weighted imaging sequence of each space unit in the space to be evaluated, wherein the method comprises the steps of configuring the regulation parameters of the second nuclear magnetic resonance system according to first preset parameter values for each space unit, respectively exciting nuclear magnetic resonance gas probes in the space units by using the second nuclear magnetic resonance system to obtain first nuclear magnetic resonance signals of each acquisition time, configuring the regulation parameters of the second nuclear magnetic resonance system according to second preset parameter values, respectively excitin