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CN-121978330-A - Kit for joint inspection of multiple virus antigens

CN121978330ACN 121978330 ACN121978330 ACN 121978330ACN-121978330-A

Abstract

The invention belongs to the technical field of virus detection, and particularly discloses a multi-virus antigen joint inspection kit, which comprises a cylindrical kit, wherein a plurality of slots which are arranged in a circumferential array are arranged on the side wall of the kit, each slot extends towards the center of the kit along the radial direction of the kit, a detection strip is movably inserted into each slot, an observation port is formed in the top of each slot, corresponding to the detection area of the detection strip, a sample adding port is formed in the center of the kit, a downward-inclined flow guide channel is communicated between the bottom of the sample adding port and each slot, and a closure assembly is movably arranged at the communication position of the flow guide channel and the slot. According to the invention, samples can be accurately distributed to each detection strip, so that the sample introduction quantity of each detection strip is ensured to be uniform, the accuracy of detection results is improved, the efficiency of multi-virus combined screening is greatly improved, and after detection is finished, the outlet of a diversion channel is blocked by automatically falling down through a shutoff assembly, so that the residual samples are directly absorbed.

Inventors

  • DING XIAOHUI

Assignees

  • 上海基宣科技有限公司
  • 上海赫景医药科技有限公司

Dates

Publication Date
20260505
Application Date
20260212

Claims (10)

  1. 1. The kit is characterized by comprising a cylindrical kit (1), wherein a plurality of slots (2) arranged in a circumferential array are arranged on the side wall of the kit (1), each slot (2) extends towards the center of the kit (1) along the radial direction of the kit (1), and a detection strip (3) is movably inserted into each slot (2); An observation port (4) is formed in the top of each slot (2) and corresponds to the position of a detection area of the detection strip (3), a sample adding port (5) is formed in the center of the kit (1), and a downward-inclined flow guide channel (6) is communicated between the bottom of the sample adding port (5) and each slot (2); The flow guide channel (6) is movably provided with a shutoff component (7) at the communication position of the slot (2).
  2. 2. The kit for combined detection of multiple viral antigens according to claim 1, wherein the aperture of the inlet end of said slot (2) is gradually reduced from outside to inside.
  3. 3. The kit for combined detection of multiple viral antigens according to claim 1, wherein the caliber of said viewing port (4) gradually decreases from top to bottom.
  4. 4. The kit for combined detection of multiple virus antigens according to claim 1, wherein the bottom of one side of the observation port (4) close to the sample addition port (5) is a smooth transition curved surface (41).
  5. 5. The kit for combined detection of multiple viral antigens according to claim 1, wherein said sample inlet (5) is of funnel-shaped configuration.
  6. 6. The kit for combined detection of multiple virus antigens according to claim 1, wherein a cover body (8) is detachably embedded at the top of the sample adding port (5), and a handle (9) is fixedly connected to the center of the cover body (8).
  7. 7. The multi-virus antigen joint inspection kit according to claim 1, wherein a cover body (8) is fixedly embedded at the top of the sample adding port (5), the cover body (8) comprises a first fixed ring (81) and a second fixed ring (82) concentrically arranged inside the first fixed ring (81), the first fixed ring (81) is fixedly embedded at the top of the sample adding port (5), and a transparent observation window (83) is fixedly connected between the first fixed ring (81) and the second fixed ring (82); the sealing plug (84) is detachably embedded in the second fixing ring (82), the top of the sealing plug (84) is fixedly connected with the handle (9), and the bottom of the second fixing ring (82) is fixedly connected with the sample adding funnel.
  8. 8. The kit for combined detection of multiple virus antigens according to claim 7, wherein a conical protrusion (10) is arranged at the center of the bottom surface of the sample adding port (5), the inlets of the plurality of flow guiding channels (6) are arranged around the conical protrusion (10) in a circumferential array, and the outlet of the sample adding funnel is positioned right above the conical protrusion (10).
  9. 9. A multi-virus antigen joint detection kit according to claim 1, wherein the interception component (7) comprises a wedge-shaped interception block (71), and the top and bottom of the slot (2) are provided with first limit grooves (72) for moving the interception block (71); the device is characterized in that the intercepting block (71) is provided with a limiting hole (73) with an upward opening, a reset spring (74) is arranged in the limiting hole (73), and two ends of the reset spring (74) are fixedly connected to the intercepting block (71) and the kit (1) respectively.
  10. 10. The multi-virus antigen joint inspection kit according to claim 9, wherein the intercepting block (71) is fixedly connected with a water absorbing cotton (75) close to the diversion channel (6), and second limiting grooves (76) for moving the water absorbing cotton (75) are formed in the top and the bottom of the slot (2).

Description

Kit for joint inspection of multiple virus antigens Technical Field The invention belongs to the technical field of virus detection, and particularly relates to a kit for joint detection of multiple virus antigens. Background In clinical diagnosis and public health monitoring, it is important to identify pathogen infection quickly and accurately. Especially for respiratory, digestive or blood transmitted viruses, the initial symptoms of the infection are often similar, but the treatment and prevention strategies are quite different, such as influenza virus, respiratory syncytial virus, adenovirus, etc. Traditional etiology diagnosis mainly relies on methods such as virus isolation and culture, nucleic acid detection (e.g., PCR), single pathogen antigen detection, and the like. The method has the advantages of long time consumption of virus isolation and culture and severe requirements on experimental conditions, high sensitivity of nucleic acid detection, high cost and relatively long fruiting time, but needs precise instruments and professional operators, and is difficult to popularize in basic medical institutions or on-site rapid screening. The antigen detection based on the immunological principle, especially the colloidal gold or fluorescence immunochromatography, has become an important tool for bedside detection and early screening because of the advantages of simple and rapid operation (usually obtaining results within 15-30 minutes), no need of special equipment, low cost and the like. Patent CN220171052U discloses a multiple virus antigen joint inspection kit, including bottom plate, top cap and the test strip that many different virus antigens correspond, offered a plurality of standing grooves on the bottom plate, a plurality of standing grooves use the center of bottom plate to be the circumference and distribute as the centre of a circle, the test strip is arranged in the standing groove, the test strip includes the welt and sets up the application of sample pad, the colloidal gold pad on the welt according to the order, detects pad and the pad that absorbs water, is equipped with detection line and quality control line on the detection pad, and the top cap lid is established on the bottom plate, has offered the observation hole of the detection line and the quality control line of a plurality of cooperation test strips on the top cap, and the application of sample hole has been seted up at the middle part of top cap, and the application of sample pad of many test strips one end is arranged in application of sample hole department. The test strips corresponding to different viruses are assembled on the same kit, so that antigens of a plurality of different viruses can be detected on the same kit, rapid identification detection is realized, detection results are conveniently checked by detection personnel, and confusion is avoided. Although the antigen that detects multiple different viruses on this patent can realize same kit, its application of sample hole does not possess the reposition of redundant personnel function, and the sample relies on the advection to adsorb completely, can not accurately realize the effect to the equal application of sample of different test paper fast, standing groove and application of sample hole direct intercommunication moreover, the test paper strip is directly inlayed and is established on the standing groove, sample treatment inhales from the end of test paper strip, still can be immersed from the bottom surface of test paper strip, pollute whole test paper strip, and this device is after the detection is accomplished, remaining sample is inconvenient to handle. The patent CN222318961U discloses a multi-virus antigen joint inspection kit, which comprises a kit, wherein a plurality of detection strip mounting grooves are formed in the outer wall of the kit, detection strips are mounted in the detection strip mounting grooves, the upper surface of the kit is provided with a communication groove, the communication groove is communicated with the plurality of detection strip mounting grooves, a flow dividing assembly is arranged in the communication groove, the flow dividing assembly comprises a flow dividing cylinder, the flow dividing cylinder is fixed in the communication groove, each detection strip can be contacted with a detection sample in the flow dividing cylinder through a communication needle tube which is provided with a puncture rubber film, the phenomenon that the detection strips cannot be contacted is avoided, the detection stability of the kit is improved, a plurality of groups of detection strips can be mounted through the plurality of detection strip mounting grooves, and the detection strips can be contacted with the sample through the communication needle tube through the rubber film, so that the sample can be subjected to multiple detection, and the detection efficiency is improved. This patent shunts through needle tubing form, can equall