CN-121982163-A - Nuclear medicine image generation method, apparatus, computer device, readable storage medium and program product

CN121982163ACN 121982163 ACN121982163 ACN 121982163ACN-121982163-A

Abstract

The application relates to a nuclear medicine image generation method, a device, computer equipment, a readable storage medium and a program product, wherein the method comprises the steps of obtaining motion information and scanning raw data of a scanned object at each time point in a scanning period, determining motion corrected distributed centroid coordinates of the scanned object at each time point according to the motion information and the scanning raw data of each time point, determining reference centroid coordinates according to the motion corrected distributed centroid coordinates of each time point, screening the motion information of each time point according to the reference centroid coordinates to obtain processed motion information, and obtaining a nuclear medicine image of the scanned object according to the processed motion information and the scanning raw data. By adopting the method, unreliable motion information can be effectively identified and removed, and the accuracy and reliability of the obtained processed motion information are improved, so that the effect of generating images is ensured.

Inventors

LU YIHUAN
ZHAO YIZHANG

Assignees

上海联影医疗科技股份有限公司

Dates

Publication Date: 20260505
Application Date: 20241031

Claims (10)

1. A method of nuclear medicine image generation, the method comprising: Acquiring motion information and scan generation data of a scanned object at various time points during scanning; Determining the motion corrected distributed centroid coordinates of the scanned object at each time point according to the motion information of each time point and the scanning raw data; determining a reference centroid coordinate according to the motion corrected distributed centroid coordinates of each time point; Screening the motion information of each time point according to the reference centroid coordinates to obtain the processed motion information; And obtaining the nuclear medicine image of the scanned object according to the processed motion information and the scanning raw data.
2. The method of claim 1, wherein said determining reference centroid coordinates from motion corrected distributed centroid coordinates for each of said time points comprises: dividing each time point into a plurality of time periods; Respectively carrying out mean value processing on the motion corrected distributed centroid coordinates in each time period to obtain a coordinate mean value of each time period; And carrying out averaging treatment again on the coordinate mean value of each time period, and taking the obtained average value as the reference centroid coordinate.
3. The method of claim 2, wherein the dividing each of the time points into a plurality of time periods comprises: Determining a plurality of motion-free time periods according to the motion-corrected distributed centroid coordinates of each time point, wherein the distance between the motion-corrected distributed centroid coordinates of every two time points in each motion-free time period is smaller than a distance threshold value, and the distance between the motion-corrected distributed centroid coordinates of every two adjacent motion-free time periods is larger than the distance threshold value; the plurality of motionless time periods are taken as divided plurality of time periods.
4. The method according to claim 2, wherein said filtering the motion information at each of said time points according to said reference centroid coordinates to obtain processed motion information comprises: acquiring the deviation amount of the coordinate mean value of each time period relative to the reference centroid coordinate; screening abnormal time periods of which the corresponding deviation values do not meet preset conditions from the time periods; And removing the motion information contained in the abnormal time period from the motion information of each time period to obtain the processed motion information.
5. The method of claim 1, wherein the filtering the motion information at each of the time points according to the reference centroid coordinates to obtain processed motion information, further comprises: For each point in time, obtaining the deviation amount of the motion corrected distributed centroid coordinates of the point in time relative to the reference centroid coordinates; And removing the motion information of which the deviation does not meet a preset condition from the motion information of each time point to obtain the processed motion information.
6. The method of claim 5, wherein the motion information of each time point is acquired in a first manner, and the filtering the motion information of each time point according to the reference centroid coordinates, after obtaining the processed motion information, further comprises: Determining an abnormal time point corresponding to the removed motion information; determining new motion information corresponding to the abnormal time point in a second mode, and replacing the motion information corresponding to the abnormal time point with the new motion information to obtain adjusted motion information of the scanned object; and obtaining the nuclear medicine image of the scanned object according to the adjusted motion information, the processed motion information and the scanning raw data.
7. A nuclear medicine image generating apparatus, the apparatus comprising: a data acquisition module for acquiring motion information and scan generation data of the scanned object at various time points during the scan; The coordinate determining module is used for determining the distribution centroid coordinates of the motion correction of the scanned object at each time point according to the motion information of each time point and the scanning raw data; The reference determining module is used for determining reference centroid coordinates according to the motion corrected distributed centroid coordinates of each time point; The information screening module is used for screening the motion information of each time point according to the reference centroid coordinates to obtain the processed motion information; And the image generation module is used for obtaining the nuclear medicine image of the scanned object according to the processed motion information and the scanning raw data.
8. A computer device comprising a memory and a processor, the memory storing a computer program, characterized in that the processor implements the steps of the nuclear medicine image generation method of any one of claims 1 to 6 when the computer program is executed.
9. A computer-readable storage medium, on which a computer program is stored, characterized in that the computer program, when being executed by a processor, implements the steps of the nuclear medicine image generating method of any one of claims 1 to 6.
10. A computer program product comprising a computer program, characterized in that the computer program, when being executed by a processor, implements the steps of the nuclear medicine image generating method of any one of claims 1 to 6.

Description

Nuclear medicine image generation method, apparatus, computer device, readable storage medium and program product Technical Field The present application relates to the field of nuclear medicine imaging technology, and in particular, to a nuclear medicine image generation method, a device, a computer apparatus, a computer readable storage medium and a computer program product. Background Radionuclide emission computed tomography (Emission Computed Tomography, ECT) includes PET (Positron Emission Computed Tomography ) and SPECT (Single Photon Emission Computed Tomography, single photon emission computed tomography), and in the nuclear medicine imaging study based on the above method, since the scanning time of the nuclear medicine imaging device is long, the scanned object easily moves during the scanning process, and the movement can cause image artifacts, inaccurate quantification and other problems, which affect the subsequent diagnosis. Thus, motion information is typically acquired during a nuclear medicine scan to perform motion correction. In the related art, motion correction is generally achieved by acquiring a set of motion information describing the motion condition of a scanned object in an acquisition period, and reconstructing a nuclear medicine image in combination with the motion information. However, the motion information of a part of the time slices is not reliable due to the influence of the motion information acquisition mode, so that the effect of reconstructing the image is affected. Disclosure of Invention Based on this, it is necessary to provide a nuclear medicine image generating method, apparatus, computer device, computer readable storage medium and computer program product for the technical problem that the effect of reconstructing an image is affected because the motion information of a part of the time slices is unreliable. In a first aspect, the present application provides a nuclear medicine image generation method. The method comprises the following steps: Acquiring motion information and scan generation data of a scanned object at various time points during scanning; Determining the motion corrected distributed centroid coordinates of the scanned object at each time point according to the motion information of each time point and the scanning raw data; determining a reference centroid coordinate according to the motion corrected distributed centroid coordinates of each time point; Screening the motion information of each time point according to the reference centroid coordinates to obtain the processed motion information; And obtaining the nuclear medicine image of the scanned object according to the processed motion information and the scanning raw data. In one embodiment, the determining the reference centroid coordinates according to the motion corrected distributed centroid coordinates of each of the time points includes: dividing each time point into a plurality of time periods; Respectively carrying out mean value processing on the motion corrected distributed centroid coordinates in each time period to obtain a coordinate mean value of each time period; And carrying out averaging treatment again on the coordinate mean value of each time period, and taking the obtained average value as the reference centroid coordinate. In one embodiment, the dividing each of the time points into a plurality of time periods includes: Determining a plurality of motion-free time periods according to the motion-corrected distributed centroid coordinates of each time point, wherein the distance between the motion-corrected distributed centroid coordinates of every two time points in each motion-free time period is smaller than a distance threshold value, and the distance between the motion-corrected distributed centroid coordinates of every two adjacent motion-free time periods is larger than the distance threshold value; the plurality of motionless time periods are taken as divided plurality of time periods. In one embodiment, the filtering the motion information of each time point according to the reference centroid coordinates to obtain processed motion information includes: acquiring the deviation amount of the coordinate mean value of each time period relative to the reference centroid coordinate; screening abnormal time periods of which the corresponding deviation values do not meet preset conditions from the time periods; And removing the motion information contained in the abnormal time period from the motion information of each time period to obtain the processed motion information. In one embodiment, the filtering processing is performed on the motion information of each time point according to the reference centroid coordinates to obtain processed motion information, and the method further includes: For each point in time, obtaining the deviation amount of the motion corrected distributed centroid coordinates of the point in time relative to the reference centroid coordinates;