CN-121983498-A - Mass spectrometer and sealing and transferring integrated device thereof

CN121983498ACN 121983498 ACN121983498 ACN 121983498ACN-121983498-A

Abstract

The invention discloses a mass spectrometer and a sealing and transferring integrated device thereof, wherein the device comprises a lifting mechanism corresponding to a sample inlet of a sample inlet chamber, a separable chip carrier for containing a detection chip is borne on the lifting mechanism, and a translation device borne in a main vacuum chamber, wherein the translation device comprises a material carrying platform assembled in the main vacuum chamber in a sliding manner, a supporting column group fixed on one side of the material carrying platform, and a sample inlet driving mechanism for driving the material carrying platform to reciprocate between an analysis position and the lifting mechanism, and a locking position for being in butt joint with the supporting column group is arranged at the bottom of the chip carrier. The whole sample injection process is simpler and more convenient, the sample injection and the sealing withdrawal actions are synchronously carried out, the sample injection efficiency is greatly improved, meanwhile, the lifting action of the lifting mechanism is directly pushed by the driving part, the independent driving control of the lifting mechanism is omitted, and the control complexity is reduced.

Inventors

WANG WENZHONG
ZENG WEIJUN
HU JUN
QIAN JUN
CAO JINGYU
SUN HAIXUAN

Assignees

中科质鑫(常州)医疗科技有限公司

Dates

Publication Date: 20260505
Application Date: 20251229

Claims (10)

1. A seal transfer integrated device for a mass spectrometer, comprising: The lifting mechanism is corresponding to the sample inlet of the sample chamber and is provided with a separable chip carrier for containing the detection chip, and The translation device is loaded in the main vacuum chamber and comprises a material loading platform assembled in the main vacuum chamber in a sliding manner, a supporting column group fixed on one side of the material loading platform, and a sample injection driving mechanism for driving the material loading platform to reciprocate between an analysis position and a lifting mechanism, wherein the bottom of the chip carrier is provided with a locking position for being in butt joint with the supporting column group; One side of the material carrying platform is also provided with a driving part, when the material carrying platform is driven by the sample injection driving mechanism to move forwards to be close to the lifting mechanism, the driving part can prop against the lifting mechanism to generate lifting driving force, the lifting mechanism is driven to lift by the lifting driving force to prop up the chip carrier to press the sample injection chamber to seal the sample injection port, and when the material carrying platform is driven by the sample injection driving mechanism to move backwards to be far away from the lifting mechanism, the lifting mechanism descends and enables the supporting upright post group to butt against the locking position to drive the chip carrier to move to an analysis position.
2. The integrated seal transfer device for a mass spectrometer of claim 1, wherein the lifting mechanism is a scissor lift platform and the lift control end has a driving roller for abutting against the driving portion.
3. The seal transfer integrated device for a mass spectrometer of claim 2, wherein the scissor lift platform comprises: A load-bearing base fixed to the main vacuum chamber; Two groups of first connecting rods and second connecting rods which are oppositely arranged at two sides of the bearing base and are in scissor-fork type mutual hinging, the lower end of the first connection is hinged with the bearing base, the lower end of the second connecting rod is assembled with the bearing base in a sliding way, the driving roller is connected with the lower end of the second connecting rod, and The support plate is used for supporting the chip carrier, the upper end of the first connecting rod is assembled on the support plate in a sliding mode, and the upper end of the second connecting rod is hinged to the support plate.
4. The integrated device for sealing and transferring a mass spectrometer according to claim 3, wherein a reset elastic member is further provided between the support base and the pallet, and is configured to form an elastic tension for driving the pallet to descend and reset when the pallet is lifted.
5. The integrated device for sealing and transferring a mass spectrometer according to claim 3 or 4, wherein the two sides of the supporting plate are provided with limit side pins, and the bottom of the chip carrier is provided with limit guide grooves matched with the limit side pins.
6. The integrated device for sealing and transferring a mass spectrometer of claim 5, wherein the support plate is further provided with a positioning pin for limiting a placement position of a chip carrier, and the chip carrier is located under the sample inlet when contacting with the positioning pin.
7. The integrated seal transfer device for a mass spectrometer of claim 5, wherein a side upper surface of the support plate facing the translation device is provided with a first guide slope, and a side lower surface of the chip carrier facing away from the translation device is provided with a second guide slope.
8. The seal transfer integrated device for a mass spectrometer according to claim 3 or 4, wherein the loading platform comprises: the first carrier seat is slidably assembled in the main vacuum chamber along a first direction approaching to or separating from the lifting mechanism, and the sample injection driving mechanism is in driving connection with the first carrier seat; The second carrying seat is assembled on the first carrying seat in a sliding manner along a second direction perpendicular to the first direction, one side of the second carrying seat is provided with a U-shaped opening with the width larger than that of the lifting mechanism, the supporting upright post group is positioned at two sides of the U-shaped opening, and The adjusting driving mechanism is carried on the first carrying seat and used for driving the second carrying seat to reciprocate along the second direction.
9. The integrated device for sealing and transferring a mass spectrometer of claim 8, wherein the support column group comprises at least four support columns fixed on the second carrier, the top ends of the support columns are provided with insertion bayonet locks, and the locking positions are positioning pin holes matched with the insertion bayonet locks.
10. A mass spectrometer, comprising: The main vacuum chamber is also connected with a backing pump for vacuumizing, the main vacuum chamber is also connected with a vacuum pump for vacuumizing, and the sample inlet for placing the detection chip is arranged on the sample chamber The seal transfer integrated device according to any one of claims 1 to 9.

Description

Mass spectrometer and sealing and transferring integrated device thereof Technical Field The invention relates to the technical field of mass spectrum detection, in particular to a mass spectrometer and a sealing and transferring integrated device thereof. Background A mass spectrometer is a high-precision scientific instrument that performs qualitative and quantitative analysis of a sample by generating, separating, and detecting gaseous ions. The core components of the ion source, the mass analyzer, the detector and the like must work in high vacuum or even ultra-high vacuum environment to avoid the collision of ions and residual gas molecules to scatter or unnecessary reaction, thereby ensuring the resolution, the sensitivity and the accuracy of analysis. In order to achieve that the sample is fed into the analysis zone without damaging the high vacuum environment of the main vacuum system, modern mass spectrometers generally employ a buffer sample-feeding chamber structure, which is typically a separate, smaller-volume pre-processing vacuum chamber. The standard working flow is that firstly, loading the sample-bearing target into the sampling chamber under normal pressure, closing the sealing valve at the outer side of the sampling chamber, then, pre-vacuumizing the sampling chamber by utilizing the backing pump to reduce the pressure of the sampling chamber to a level similar to that of the main vacuum chamber, and finally, opening the sealing valve at the inner side of the main vacuum chamber, and sending the sample into the analysis position. The process effectively avoids the direct exposure of the main vacuum cavity to the atmosphere, greatly improves the sampling efficiency and protects high vacuum pumps such as expensive turbomolecular pumps. The sealing structure is a key link in the design of the sample injection chamber, and the performance of the sealing structure directly determines the maintenance capability of the vacuum degree in the main vacuum chamber, the sample injection efficiency and the reliability of long-term operation of the system. At present, the common sealing mode of the sample injection chamber of the mass spectrometer mainly relies on a pressing mechanism positioned in a main vacuum cavity, wherein the pressing mechanism presses a sealing flat plate upwards to the bottom of the sample injection chamber, and sealing is realized by compressing an O-shaped ring between the sealing flat plate and the sample injection chamber. And when sample injection is performed, the sealing action of the pressing mechanism is firstly canceled, and then the detection chip is sent to the analysis position through the sample feeding mechanism, so that the overall sample injection efficiency is greatly restricted, and the overall sample injection action is complex. Disclosure of Invention In order to overcome the defects of the prior art, the invention aims to provide a mass spectrometer and a sealing and transferring integrated device thereof, which have the advantages of simplifying the sample injection process and improving the sample injection efficiency. The invention adopts the following technical scheme: According to a first aspect of embodiments of the present disclosure, there is provided a seal transfer integrated device for a mass spectrometer, comprising: The lifting mechanism is corresponding to the sample inlet of the sample chamber and is provided with a separable chip carrier for containing the detection chip, and The translation device is loaded in the main vacuum chamber and comprises a material loading platform assembled in the main vacuum chamber in a sliding manner, a supporting column group fixed on one side of the material loading platform, and a sample injection driving mechanism for driving the material loading platform to reciprocate between an analysis position and a lifting mechanism, wherein the bottom of the chip carrier is provided with a locking position for being in butt joint with the supporting column group; One side of the material carrying platform is also provided with a driving part, when the material carrying platform is driven by the sample injection driving mechanism to move forwards to be close to the lifting mechanism, the driving part can prop against the lifting mechanism to generate lifting driving force, the lifting mechanism is driven to lift by the lifting driving force to prop up the chip carrier to press the sample injection chamber to seal the sample injection port, and when the material carrying platform is driven by the sample injection driving mechanism to move backwards to be far away from the lifting mechanism, the lifting mechanism descends and enables the supporting upright post group to butt against the locking position to drive the chip carrier to move to an analysis position. According to the technical scheme, when detection analysis sample injection is carried out, the sample injection driving mechanism is used for controlling the