CN-121985932-A - Composition suitable for skin care

Abstract

The present invention relates to a composition for skin care. In particular, the present invention relates to skin care compositions comprising myrrh resin extract and retinoids. The invention also relates to a method for treating skin using said composition, and to a method for enhancing the anti-ageing effect of retinoids in the skin layers.

Inventors

• PARSA RAMINE
• R. PATEL
• W-H.T.Li

Assignees

• 科赴品牌有限责任公司

Dates

Publication Date

20260505

Application Date

20241003

Priority Date

20231005

Claims (18)

1. 1. A skin care composition is provided, which comprises a skin care composition, the skin care composition comprises: a. Myrrh resin extract, and B. Retinoids.
2. 2. The skin care composition of claim 1 wherein the myrrh resin extract is produced from a resin of a plant of the genus myrrh.
3. 3. The skin care composition according to claim 2, wherein the myrrh resin extract is obtained by extraction with an organic solvent.
4. 4. The skin care composition of claim 1, wherein the myrrh resin extract is present in an amount ranging from about 0.000001% to about 10% by total weight of the composition.
5. 5. The skin care composition of claim 1 wherein the retinoid is selected from the group consisting of retinol, retinal, retinol esters, retinoic acid, derivatives thereof, and combinations thereof.
6. 6. The skin care composition according to claim 1, wherein the retinoid is present in an amount ranging from about 0.001% to about 10% by total weight of the composition.
7. 7. The skin care composition of claim 1, wherein the ratio of myrrh resin to retinoid is from about 100:1 to about 1:10.
8. 8. The skin care composition of claim 1 further comprising an ingredient selected from the group consisting of surfactants, chelating agents, emollients, humectants, conditioning agents, preservatives, sunscreens, fragrances, and combinations of two or more thereof.
9. 9. The skin care composition of claim 1, wherein the composition is in the form of a solution, suspension, emulsion, lotion, cream, slurry, gel, stick, spray, ointment, liquid lotion, soap bar, shampoo, conditioner, paste, foam, powder, mousse, shaving cream, hydrogel, or film-forming product.
10. 10. The skin care composition according to claim 1 comprising: a. From about 0.01% to about 2.0% by weight of a myrrh resin extract, based on the total weight of the composition, and B. from about 0.01% to about 1.0% by weight of retinol based on the total weight of the composition.
11. 11. A method of skin treatment comprising topically applying to the skin the composition of claim 1.
12. 12. A method of treating signs of skin aging comprising topically applying the skin care composition of claim 1 to skin in need of treatment for skin aging.
13. 13. A method for enhancing the anti-aging effect of retinoids in a skin layer of skin in need thereof, the method comprising topically applying to the skin care composition of claim 1.
14. 14. A method for increasing CRABP2 or AQP3 expression in skin cells, the method comprising topically applying to the skin care composition of claim 1.
15. 15. The method of claim 14, wherein the retinoid is selected from the group consisting of retinol, retinal, retinol esters, retinoic acid, derivatives thereof, and combinations thereof.
16. 16. The method of claim 14, wherein the retinol is present in an amount in the range of about 0.001% to about 10% by total weight of the composition.
17. 17. The method of claim 14, wherein the myrrh resin extract is present in an amount ranging from about 0.001% to about 10% by total weight of the composition.
18. 18. The method of claim 14, wherein the skin care composition topically applied to the skin comprises: a. From about 0.01% to about 2.0% by weight of a myrrh resin extract, based on the total weight of the composition, and B. from about 0.01% to about 1.0% by weight of retinol based on the total weight of the composition.

Description

Composition suitable for skin care Cross Reference to Related Applications The present application claims the benefit of U.S. provisional application 63/588,030 filed on 5/10/2023, the complete disclosure of which is hereby incorporated by reference for all purposes. Technical Field The present invention relates generally to compositions for skin care. In particular, the present invention relates to skin care compositions comprising myrrh resin extract and retinoids. The invention also relates to a method of treating skin using said composition. Background Human skin undergoes certain aging processes, partly attributable to intrinsic processes (e.g., time aging) and partly attributable to external factors (e.g., photoaging). In addition, the skin may undergo transient or even sustained changes such as acne, oily or dry skin, keratosis, rosacea, light sensitivity, inflammation, erythema nodosum and allergic or autoimmune reactions such as dermatological and photo-inflammatory skin diseases. The consequences of the aging process described above may include thinning of the skin, weakening of the interweaving of epidermis and dermis, and a reduction in the number of cells and blood supply vessels. These consequences are generally undesirable and individuals suffering from these problems will seek topical treatment to address them. Retinoids have been used to treat skin disorders caused by intrinsic aging, extrinsic factors, acne or skin disorders. However, retinoids can be difficult to formulate because many retinoids are prone to photodegradation and retinoids can be irritating to the skin of some individuals. Myrrh resin is a natural extract from a tree species of the genus myrrh (Commiphora). Since ancient times, myrrh resins are known for use in fragrances and pharmaceuticals, for example as preservatives. Topical application of myrrh resin to the skin may cause skin irritation. One option to avoid skin irritation caused by retinoids is to propose alternative compounds that activate the same or similar biological pathways as retinoids. However, this is a complex task, as such alternative compounds are difficult to identify. Another option would be to enhance or potentiate the beneficial effects of the retinoid, thereby limiting the amount of retinoid that is topically applied. Also, this task is complicated by the difficulty in identifying these compounds. There is a continuing need and interest to identify compounds or products that can enhance or potentiate the activation of retinoids on beneficial biological pathways without increasing the undesirable side effects of retinoids, such as skin irritation. It is particularly desirable to increase the potency of retinoids with known and authentic natural ingredients. Disclosure of Invention One aspect of the present invention relates to a skin care composition comprising a myrrh resin extract and a retinoid. This aspect may be combined with the various embodiments in any combination. Thus, in some embodiments, the myrrh resin extract is produced from a resin of a plant of the genus myrrh. In one or more embodiments, the myrrh resin extract is obtained by extraction using an organic solvent. In some embodiments, the myrrh resin extract is present in an amount ranging from about 0.000001% to about 10% by total weight of the composition. In one or more embodiments, the retinoid is selected from the group consisting of retinol, retinal, retinol esters, retinoic acid, derivatives thereof, and combinations thereof. In one or more embodiments, the retinoid is present in an amount ranging from about 0.001% to about 10% by total weight of the composition. In one or more embodiments, the ratio of myrrh resin to retinoid is from about 100:1 to about 1:10. In some embodiments, the skin care composition further comprises an ingredient selected from the group consisting of surfactants, chelating agents, emollients, moisturizers, conditioners, preservatives, sunscreens, fragrances, and combinations of two or more thereof. In one or more embodiments, the skin care composition is in the form of a solution, suspension, emulsion, lotion, cream, slurry, gel, stick, spray, ointment, liquid lotion, soap bar, shampoo, conditioner, paste, foam, powder, mousse, shave cream, hydrogel, or film-forming product. Another aspect of the invention relates to a skin care composition comprising from about 0.01% to about 2.0% by weight of myrrh resin extract, based on the total weight of the composition, and from about 0.01% to about 1.0% by weight of retinol, based on the total weight of the composition. Another aspect of the invention relates to a method of skin treatment comprising topically applying to the skin a composition of any of the embodiments described above. Another aspect of the present invention relates to a method of treating signs of skin aging comprising topically applying to skin in need of treatment for skin aging a skin care composition according to any of the embodiments d