CN-121985936-A - Composition comprising myrrh resin extract and processed oat ingredient for skin care

Abstract

The present invention relates to a composition for skin care. In particular, the present invention relates to skin care compositions comprising myrrh resin extract and processed oat ingredients. The invention also relates to a method for treating skin using said composition, and to a method for activating lipid production in a skin layer.

Inventors

• PARSA RAMINE
• P. WRIGHT
• W-H.T.Li

Assignees

• 科赴品牌有限责任公司

Dates

Publication Date

20260505

Application Date

20241003

Priority Date

20231005

Claims (20)

1. 1. A skin care composition is provided, which comprises a skin care composition, the skin care composition comprises: a. Myrrh resin extract, and B. A processed oat component.
2. 2. The skin care composition of claim 1 wherein the myrrh resin extract is produced from a resin of the genus myrrh.
3. 3. The skin care composition according to claim 2, wherein the myrrh resin extract is obtained by extraction using an organic solvent.
4. 4. The skin care composition of claim 1, wherein the myrrh resin extract is present in an amount ranging from about 0.000001% to about 10% by total weight of the composition.
5. 5. The skin care composition of claim 1, wherein the processed oat component is selected from the group consisting of fermented oats, colloidal oats, oat extracts, oat oils, and combinations thereof.
6. 6. The skin care composition according to claim 1, wherein the processed oat ingredient is present in an amount ranging from about 0.001% to about 10% by total weight of the composition.
7. 7. The skin care composition of claim 1, wherein the weight ratio of myrrh resin extract to processed oat ingredient is from about 10:1 to about 1:1000.
8. 8. The skin care composition of claim 1 further comprising an ingredient selected from the group consisting of surfactants, chelating agents, emollients, humectants, conditioning agents, preservatives, sunscreens, fragrances, and combinations of two or more thereof.
9. 9. The skin care composition of claim 1, wherein the composition is in the form of a solution, suspension, emulsion, lotion, cream, essence, gel, stick, spray, ointment, liquid lotion, soap bar, shampoo, conditioner, paste, foam, powder, mousse, shave cream, hydrogel, or film-forming product.
10. 10. The skin care composition according to claim 1 comprising: a. From about 0.005% to about 1.5% by weight of the total weight of the composition of myrrh resin extract, and B. A processed oat ingredient selected from the group consisting of oat oil, from about 0.1% to about 2.5% by weight based on the total weight of the composition.
11. 11. A method of skin treatment comprising topically applying to the skin the composition of claim 1.
12. 12. A method of treating signs of skin aging comprising topically applying the skin care composition of claim 1 to skin in need of treatment for skin aging.
13. 13. A method for activating lipid production in a skin layer of skin in need thereof, the method comprising topically applying to the skin care composition of claim 1.
14. 14. A method for activating ceramide production in a skin layer of skin in need thereof, the method comprising topically applying to the skin care composition of claim 1.
15. 15. The method of claim 14, wherein the processed oat component is selected from the group consisting of fermented oats, colloidal oats, oat extracts, oat oil, and combinations thereof.
16. 16. The method of claim 14, wherein the processed oat ingredient is present in an amount ranging from about 0.001% to about 10% by total weight of the skin care composition.
17. 17. The method of claim 14, wherein the myrrh resin extract is present in an amount ranging from about 0.000001% to about 10% by total weight of the composition.
18. 18. The method of claim 14, wherein the skin care composition topically applied to the skin comprises: a. From about 0.005% to about 1.5% by weight of the total weight of the composition of myrrh resin extract, and B. A processed oat ingredient selected from the group consisting of oat oil, from about 0.1% to about 2.5% by weight based on the total weight of the composition.
19. 19. A method for enhancing skin barrier by stimulating skin barrier gene expression, such as endo-chaperonin, filaggrin and paphiopediin expression, in a skin layer of skin in need thereof, the method comprising topically applying to the skin care composition of claim 1.
20. 20. A method for enhancing the anti-aging effect of processed oats in a skin layer of skin in need thereof, the method comprising topically applying to the skin care composition of claim 1.

Description

Composition comprising myrrh resin extract and processed oat ingredient for skin care Cross Reference to Related Applications The application claims the benefit of U.S. provisional application 63/588,036 filed on 5, 10, 2023, the entire disclosure of which is hereby incorporated by reference for all purposes. Technical Field The present invention relates generally to compositions for skin care. In particular, the present invention relates to skin care compositions comprising myrrh resin extract and processed oat ingredients. The invention also relates to a method of treating skin using said composition. Background Human skin undergoes certain aging processes, partly attributable to intrinsic processes (e.g., time aging) and partly attributable to external factors (e.g., photoaging). In addition, the skin may undergo transient or even sustained changes such as acne, oily or dry skin, keratosis, rosacea, light sensitivity, inflammation, erythema nodosum and allergic or autoimmune reactions such as dermatological and photo-inflammatory skin diseases. The consequences of the aging process described above may include thinning of the skin, weakening of the interweaving of epidermis and dermis, and a reduction in the number of cells and blood supply vessels. These consequences are generally undesirable and individuals suffering from these problems will seek topical treatment to address them. Oat lipids are known to have anti-inflammatory effects and dual PPARa and PPARb/d agonist activity, and also induce keratinocyte differentiation and ceramide synthesis in primary human keratinocytes, which may provide skin barrier improvement (Su-Hyoun Chon et al, experimental Dermatology, 2015, 24, 290-295). Colloidal oats have a high lipid content (3% -18%) compared to other grains, and the lipid fraction, oat oil, is rich in unsaturated fatty acids (Banas A et al, J Exp Bot 2007:58:2463-2470). Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear receptors that regulate lipid homeostasis in our body. In the skin, PPAR receptor activation is known to improve epidermal barrier function, exert anti-inflammatory effects, and accelerate the wound healing process (Schmuth M et al, J Lipid Res 2008:49:499-509). The myrrh resin is a natural extract from a seed of the genus myrrh (Commiphora) tree. Myrrh resins have been known from ancient times for their use in perfumes and pharmaceuticals, for example as preservatives. Topical application of myrrh resin to the skin may result in skin irritation. It is challenging to treat skin conditions associated with aging, such as skin atrophy, acne, photoaging, and to reduce the appearance of wrinkles, fine lines, stretch marks, or cellulite. Consumers are cautious about products they use locally and are increasingly interested in active ingredients of natural origin. Accordingly, there is a need to provide natural extracts that can improve the epidermal barrier function and provide anti-inflammatory effects. It is particularly desirable to increase the potential of known and trustworthy natural ingredients that are both effective and gentle enough to the skin to be well tolerated. Disclosure of Invention One aspect of the present invention relates to a skin care composition comprising a myrrh resin extract and a processed oat ingredient. This aspect may be combined with the various embodiments in any combination. Thus, in some embodiments, the myrrh resin extract is produced from a resin of the myrrh genus plant. In one or more embodiments, the myrrh resin extract is obtained by extraction using an organic solvent. In some embodiments, the myrrh resin extract is present in an amount ranging from about 0.000001% to about 10% by total weight of the composition. In one or more embodiments, the processed oat component is selected from the group consisting of fermented oats, colloidal oats, oat extracts, oat oil, and combinations thereof. In one or more embodiments, the processed oat ingredient is present in an amount ranging from about 0.001% to about 10% by total weight of the composition. In one or more embodiments, the weight ratio of myrrh resin extract to processed oat ingredient is about 10:1 to about 1:1000. In some embodiments, the skin care composition further comprises an ingredient selected from the group consisting of surfactants, chelating agents, emollients, moisturizers, conditioners, preservatives, sunscreens, fragrances, and combinations of two or more thereof. In one or more embodiments, the skin care composition is in the form of a solution, suspension, emulsion, lotion, cream, essence, gel, stick, spray, ointment, liquid lotion, soap bar, shampoo, conditioner, paste, foam, powder, mousse, shave cream, hydrogel, or film-forming product. Another aspect of the present invention relates to a skin care composition comprising from about 0.005 wt% to about 1.5 wt% of a myrrh resin extract, based on the total weight of the composition, and from about 0.1 wt