CN-121986941-A - Cardiovascular and cerebrovascular maintenance nutritional supplement

Abstract

The invention discloses a full-peptide compound preparation for cardiovascular and cerebrovascular maintenance, which comprises a core layer and an outer coating, wherein the core layer comprises small molecular peptides derived from Buyang Huanwu decoction and modern bioactive components, and the outer coating is moisture-proof, slow-release or enteric coating. The preparation has stable structure and good absorption and utilization effects, is suitable for the fields of functional foods, health-care foods, special diets and the like, and has good industrialization prospect.

Inventors

• LIU DEYUAN

Assignees

• 刘德沅

Dates

Publication Date

20260508

Application Date

20260228

Claims (8)

1. 1. A peptide compound composition for cardiovascular and cerebrovascular maintenance, which is characterized by comprising: (1) The small molecule active peptide is selected from at least one of radix astragali peptide, radix Angelicae sinensis peptide, rhizoma Ligustici Chuanxiong peptide, radix Paeoniae Rubra peptide, carthami flos peptide, semen Persicae peptide and Lumbricus peptide; (2) At least one selected from hirudin, nattokinase, coenzyme Q10, PQQ, spermidine and nominoline.
2. 2. The composition of claim 1, wherein the yang-tonifying five-soup-source peptide comprises two or more.
3. 3. The composition of claim 1, wherein the yang-tonifying five-soup source peptide is all seven peptides selected from the group consisting of astragalus peptide, angelica peptide, ligusticum wallichii peptide, red paeony root peptide, safflower peptide, peach kernel peptide and earthworm peptide.
4. 4. The composition of claim 1, further comprising at least one of a sea cucumber peptide, a collagen peptide, a ginkgo peptide, a red sage peptide, and a red yeast rice peptide.
5. 5. The composition of claim 1, wherein the total content of peptides derived from the Buyang Huanwu decoction is 10% -100% by mass, and the content of the astragalus peptides is 30% -80%.
6. 6. The composition according to claim 1, wherein the total content of component (2) is 0.01% -10%.
7. 7. The preparation method of the composition according to any one of claims 1 to 6, which is characterized by comprising one or more of traditional Chinese medicine extraction, composite enzymolysis, membrane separation and purification, low-temperature concentration, nano dispersion, microcapsule embedding, liposome encapsulation and drying, and optionally comprises a three-layer coating process.
8. 8. The application of the composition in any one of claims 1-6 in preparing functional foods, health foods, special diets and medicines comprises the steps of assisting in regulating blood fat, improving blood rheological properties, maintaining vascular endothelial functions, improving microcirculation, protecting heart muscle, cerebral infarction and apoplexy sequela, and delaying vascular aging.

Description

Cardiovascular and cerebrovascular maintenance nutritional supplement Technical Field The invention belongs to the technical fields of health-care food, functional food, special diet food and related medicines, and in particular relates to a cardiovascular and cerebrovascular maintenance composition based on the compounding of traditional Chinese medicine small molecular peptide and modern bioactive components. Background Cardiovascular and cerebrovascular related health problems have become an important factor affecting the health of people. At present, related products sold on the market mainly comprise single components or are simply compounded, traditional Chinese medicine raw materials are mainly applied in the form of traditional extracts, and the problems of limited absorption and utilization rate, unobtrusive synergistic effect and the like exist. In order to further improve the stability and bioavailability of the product and enrich the choices of cardiovascular and cerebrovascular related health products, it is necessary to provide a compound composition with scientific formula, high absorption efficiency and wider applicability. Disclosure of Invention The invention aims to provide a full-peptide Chinese and western compound composition for cardiovascular and cerebrovascular maintenance, which has the characteristics of synergistic components, high absorption efficiency, good stability and the like, and can meet the application requirements of the fields of functional foods, health-care foods and the like. The invention adopts the following technical scheme: a peptide compound composition for cardiovascular and cerebrovascular maintenance comprises: (1) The small molecule active peptide is selected from at least one of radix astragali peptide, radix Angelicae sinensis peptide, rhizoma Ligustici Chuanxiong peptide, radix Paeoniae Rubra peptide, carthami flos peptide, semen Persicae peptide and Lumbricus peptide; (2) At least one selected from hirudin, nattokinase, coenzyme Q10, PQQ, spermidine and nominoline. In some embodiments, the yang-tonifying five-soup-source peptide comprises two or more. In some schemes, the yang-tonifying five-returning decoction source peptide is all seven peptides of astragalus peptide, angelica peptide, ligusticum wallichii peptide, red paeony root peptide, safflower peptide, peach kernel peptide and earthworm peptide. In some embodiments, the composition further comprises at least one of sea cucumber peptide, collagen peptide, ginkgo peptide, red sage peptide, and monascus peptide. The weight percentage is as follows: The total content of peptide source of the yang-tonifying five-returning decoction is 10% -100%, wherein the content of astragalus peptide is 30% -80%; the total content of the components (2) is 0.01% -10%. The invention also provides a preparation method of the composition, which comprises one or more of traditional Chinese medicine extraction, composite enzymolysis, membrane separation and purification, low-temperature concentration, nano dispersion, microcapsule embedding and drying, and can adopt a three-layer coating process. The invention also provides application of the composition in preparing functional foods, health-care foods, special diets and medicines, and can be used for assisting in regulating blood fat, improving blood rheological property, maintaining vascular endothelial function, improving microcirculation, protecting cardiac muscle, promoting rehabilitation after cerebral infarction and stroke, delaying vascular aging and the like. The beneficial effects are that: the full peptide technology of the traditional Chinese medicine is adopted, so that the absorption and utilization efficiency of the active ingredients is obviously improved; the traditional Chinese medicine peptide and modern bioactive components are scientifically compounded, and the multi-target synergistic effect is achieved; The formula has good stability, the preparation process is mature and controllable, and the preparation method is suitable for industrial production; The application range is wide, and the product can be applied to the fields of functional foods, health-care foods, special diets and related medicines. The specific embodiment is as follows: Example 1 50% Of astragalus peptide, 5% of angelica peptide, 5% of earthworm peptide, 10% of coenzyme Q and 100% of auxiliary materials. Example 2 Astragalus peptide 40%, angelica peptide 4%, ligusticum wallichii peptide 4%, red peony root peptide 3%, safflower peptide 3%, peach kernel peptide 3%, earthworm peptide 5%, PQQ 0.2%, spermidine 0.3%, nominoline 0.5%, and adjuvant to 100%. Example 3 45% Of astragalus peptide, 6% of earthworm peptide, 3% of hirudin, 10% of coenzyme Q, 0.2% of PQQ and 100% of auxiliary materials.