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CN-121986957-A - Electronic cigarette liquid containing traditional Chinese medicine extract and preparation method thereof

CN121986957ACN 121986957 ACN121986957 ACN 121986957ACN-121986957-A

Abstract

The invention relates to an electronic cigarette liquid containing a traditional Chinese medicine extract and a preparation method thereof. The electronic cigarette liquid comprises, by weight, 3-5 parts of a traditional Chinese medicine active component, 10-20 parts of an animal egg white protein hydrolysate, 100 parts of an alkaline carrier, wherein the alkaline carrier is a high-purity liquid alkali solution with a pH value of 10-14, the high-purity liquid alkali solution is prepared by mixing high-purity sodium hydroxide and distilled water according to a mass ratio of 1:5-10, an atomization matrix is 15-25 parts of glycerol, 450-550 parts of a solvent is a glucose aqueous solution, the traditional Chinese medicine active component is obtained by mixing ⑴ of ganoderma lucidum baking powder, animal egg white and the high-purity liquid alkali aqueous solution, standing and fermenting for 3-5 days at 25-30 ℃ to generate a small molecular active component with a molecular weight of <500Da, and ⑵ is subjected to fractional filtration by adopting a sand core funnel with a pore diameter of 16-30 mu m to remove macromolecular impurities and retain the small molecular active component with a molecular weight of less than 500 Da.

Inventors

  • ZHANG QINGZHU

Assignees

  • 中国中医药发展研究院有限公司

Dates

Publication Date
20260508
Application Date
20250617

Claims (7)

  1. 1. An electronic cigarette liquid containing traditional Chinese medicine extract is characterized by comprising the following raw materials in parts by weight: The traditional Chinese medicine active components comprise 3-5 parts of lucid ganoderma fermentation extract and 10-20 parts of animal egg white protein hydrolysate; the alkaline carrier comprises 100 parts of high-purity liquid alkali solution with the pH value of 10-12, wherein the high-purity liquid alkali solution is prepared from high-purity sodium hydroxide and distilled water according to the mass ratio of 1:5-10; 15-25 parts of atomization matrix, namely glycerin; 450-550 parts of solvent, namely glucose aqueous solution.
  2. 2. The electronic cigarette liquid containing the traditional Chinese medicine extract according to claim 1, wherein the traditional Chinese medicine active components are obtained through the following processes: ⑴ Mixing lucid ganoderma baking powder, animal egg white and high-purity aqueous alkali, standing and fermenting for 3-5 days at 25-30 ℃ to generate a micromolecule active ingredient with the molecular weight of less than 500 Da; ⑵ And (3) carrying out graded filtration by adopting a sand core funnel with the aperture of 16-30 mu m, removing macromolecular impurities, and retaining micromolecular active ingredients with the molecular weight smaller than 500 Da.
  3. 3. The electronic cigarette liquid containing traditional Chinese medicine extract according to claim 1, wherein the atomized substrate further comprises 5-15 parts of nicotine and/or 3-5 parts of tobacco extract.
  4. 4. The electronic cigarette liquid containing the traditional Chinese medicine extracting solution according to claim 1, wherein the animal egg white is egg white or duck egg white, the fermentation temperature is 28+/-1 ℃ for 4 days, the aperture of a sand core funnel is 20 mu m, the concentration of the glucose aqueous solution is 5-10wt% and the molecular weight of the ganoderma lucidum fermentation extracting solution is less than or equal to 300Da, and the pH value of the electronic cigarette liquid is 8.0-10.
  5. 5. A method for preparing the electronic cigarette liquid containing the traditional Chinese medicine extracting solution according to claim 1, which is characterized by comprising the following steps: ⑴ Preparing high-purity aqueous alkali, namely mixing high-purity sodium hydroxide with distilled water according to a mass ratio of 1 (5-10); ⑵ Fermentation and extraction, namely adding 3-5 parts of ganoderma lucidum powder and 10-20 parts of animal egg white into 100 parts of high-purity aqueous alkali with the pH value of 10-12, and standing and fermenting for 3-5 days at the temperature of 25-30 ℃, wherein the fermentation is carried out under a light-shielding condition; ⑶ Step of fractional filtration, which is to filter fermentation liquor by a G1-G6-grade sand core funnel, control the aperture to be 16-30 mu m and collect filtrate with the molecular weight of less than 500 Da; ⑷ Compounding, namely taking 20 parts of filtrate and 500 parts of glucose aqueous solution, adding 20 parts of glycerin, 5 parts of tobacco extract and 10 parts of nicotine, and homogenizing.
  6. 6. An electronic cigarette liquid containing traditional Chinese medicine extract is characterized by comprising the following raw materials in parts by weight: The traditional Chinese medicine active components comprise 3-5 parts of lucid ganoderma fermentation extract and 10-20 parts of animal egg white protein hydrolysate; the alkaline carrier comprises 100 parts of high-purity liquid alkali solution with the pH value of 10-12, wherein the high-purity liquid alkali solution is prepared from high-purity sodium hydroxide and distilled water according to the mass ratio of 1:5-10; Atomizing the substrate; 450-550 parts of solvent, namely glucose aqueous solution.
  7. 7. The electronic cigarette liquid containing traditional Chinese medicine extract according to claim 6, wherein the atomization substrate further comprises 15-25 parts of glycerin and/or 5-15 parts of nicotine and/or 3-5 parts of tobacco extract.

Description

Electronic cigarette liquid containing traditional Chinese medicine extract and preparation method thereof Technical Field The invention belongs to the technical field of electronic cigarette liquid compositions, and particularly relates to an electronic cigarette liquid atomization preparation with a health care function and containing traditional Chinese medicine extract and a preparation method thereof. Background The traditional electronic cigarette lacks a health care function, can not relieve respiratory tract inflammation and cardiovascular injury caused by smoking, is difficult to absorb by human bodies, atomizes Yi Shihuo at high temperature, has poor stability of alkaline components of tobacco tar, and can not effectively act on mucous membrane tissues. Disclosure of Invention The invention aims to provide a method for solving the problem of low bioavailability of electronic cigarette liquid of traditional Chinese medicine active ingredients, The technical scheme of the invention is that the electronic cigarette liquid containing the traditional Chinese medicine extracting solution is characterized by comprising the following raw materials in parts by weight: The traditional Chinese medicine active components comprise 3-5 parts of lucid ganoderma fermentation extract and 10-20 parts of animal egg white protein hydrolysate; the alkaline carrier comprises 100 parts of high-purity liquid alkali solution with the pH value of 10-12, wherein the high-purity liquid alkali solution is prepared from high-purity sodium hydroxide and distilled water according to the mass ratio of 1:5-10; 15-25 parts of atomization matrix, namely glycerin; 450-550 parts of solvent, namely glucose aqueous solution. The preparation method of the electronic cigarette liquid containing the traditional Chinese medicine extracting solution is characterized by comprising the following steps of: ⑴ Preparing high-purity aqueous alkali, namely mixing high-purity sodium hydroxide with distilled water according to a mass ratio of 1:5-10; ⑵ Fermentation and extraction, namely adding 3-5 parts of ganoderma lucidum powder and 10-20 parts of animal egg white into 100 parts of high-purity aqueous alkali with the pH value of 10-14, and standing and fermenting for 3-5 days at the temperature of 25-30 ℃, wherein the fermentation is carried out under a light-proof condition; ⑶ Step of fractional filtration, which is to filter fermentation liquor by a G1-G6-level sand core funnel, control the aperture to be 16-30 mu m and collect filtrate with the molecular weight less than 500 Da; ⑷ Compounding, namely taking 20 parts of filtrate and 500 parts of glucose aqueous solution, adding 20 parts of glycerin, 5 parts of tobacco extract and 10 parts of nicotine, and homogenizing. Preferably, the active components of the traditional Chinese medicine are obtained by the following processes: ⑴ Mixing lucid ganoderma baking powder, animal egg white and high-purity aqueous alkali, standing and fermenting for 3-5 days at 25-30 ℃ to generate a micromolecule active ingredient with the molecular weight of less than 500 Da; ⑵ And (3) carrying out graded filtration by adopting a sand core funnel with the aperture of 16-30 mu m, removing macromolecular impurities, and retaining micromolecular active ingredients with the molecular weight smaller than 500 Da. Preferably, the atomization substrate further comprises 5-15 parts of nicotine and/or 3-5 parts of tobacco extract. The method is characterized in that the animal egg white is egg white or duck egg white, the fermentation temperature is 28+/-1 ℃ for 4 days, the aperture of the sand core funnel is 20 mu m, the concentration of the glucose aqueous solution is 5-10wt% and the molecular weight of the ganoderma lucidum fermentation extract is less than or equal to 300Da, and the pH value of the electronic cigarette liquid is 8.0-10. The other technical proposal of the invention is that the preparation method of the electronic cigarette liquid containing the traditional Chinese medicine extracting solution is characterized by comprising the following steps: ⑴ Preparing high-purity aqueous alkali, namely mixing high-purity sodium hydroxide with distilled water according to a mass ratio of 1:5-10; ⑵ Fermentation and extraction, namely adding 3-5 parts of ganoderma lucidum powder and 10-20 parts of animal egg white into 100 parts of high-purity aqueous alkali with the pH value of 10-14, and standing and fermenting for 3-5 days at 25-30 ℃, wherein the fermentation is carried out under a light-proof condition; ⑶ Step of fractional filtration, which is to filter fermentation liquor by a G1-G6-level sand core funnel, control the aperture to be 16-30 mu m and collect filtrate with the molecular weight less than 500 Da; ⑷ Compounding, namely taking 20 parts of filtrate and 500 parts of glucose aqueous solution, adding 20 parts of glycerin, 5 parts of tobacco extract and 10 parts of nicotine, and homogenizing. The electronic cigar