CN-121987194-A - Treatment devices, methods, and systems including a piston detector

Abstract

A pen cap for a medication delivery pen includes a piston detector mechanism. The piston detector mechanism includes at least one inner housing having a first open end through which the drug delivery pen is insertable, a second end opposite the first end, a sidewall defined by an outer surface and an opposite inner surface, and a channel extending from the outer surface to the inner surface. The sidewall extends between the first end and the second end, thereby defining a pen receiving chamber therebetween. The piston detector mechanism further includes at least one switch and a translatable shaft disposed at least partially in the channel. The translatable shaft includes a body extending from at least a pen engagement portion in the pen receiving chamber to a switch engagement portion in the pen receiving chamber. The translatable shaft is oriented to travel from a first position to at least a second position to toggle the at least one switch during capping of a medication delivery pen into the inner housing.

Inventors

• J. Lefu
• A.J. Livingston
• G. Crossell
• J. JOHNSON

Assignees

• 比格福特生物医学有限公司

Dates

Publication Date

20260508

Application Date

20190505

Priority Date

20180504

Claims (20)

1. 1. A cover for a medication delivery pen, comprising: a detector mechanism, comprising: an outer housing; an inner shell comprising A first open end configured to receive a medication delivery pen, A second end opposite to the first end, and A sidewall having an outer surface and an inner surface, the sidewall extending between the first and second ends, and A passageway extending through the inner housing, At least one switch in an electronic circuit, and A translatable shaft disposed at least partially in the channel and comprising a body extending at least from a pen engagement portion in the pen receiving chamber to a switch engagement portion thereof, wherein the translatable shaft is oriented to travel from a first position to at least a second position to toggle the at least one switch.
2. 2. The case of claim 1, further comprising a first NFC antenna configured to receive at least one signal generated by an analyte sensor and located between the outer housing and a first side of the inner housing, a second NFC antenna configured to receive at least one signal generated by the analyte sensor and located between the outer housing and a second side of the inner housing, and an NFC reader in communication with the first NFC antenna and the second NFC antenna.
3. 3. The cover sleeve of claim 1, further comprising: A display; A memory; And A processor in communication with the memory.
4. 4. The cover sleeve of claim 1 wherein said second end of said inner housing defines a needle receiving chamber.
5. 5. The cover sleeve of claim 4 further comprising a limiter that limits the travel of the translatable shaft.
6. 6. The cover sleeve of claim 4 further comprising a spring positioned concentric with the shaft and disposed between the first opening and the switch engagement portion.
7. 7. The cover sleeve of claim 4 wherein said translatable shaft is offset from and travels in a direction parallel to a central axis of said inner shell.
8. 8. The cover sleeve of claim 4 wherein said at least one switch is a normally open switch.
9. 9. The cover sleeve of claim 4 further comprising a seal.
10. 10. The cover sleeve of claim 9 wherein the seal comprises a boot seal extending around a portion of the translatable shaft extending into the pen receiving chamber.
11. 11. The cover sleeve of claim 9 or 10, wherein the seal comprises a hydrophobic lubricant in the channel along the translatable shaft.
12. 12. The cover sleeve of one of the preceding claims, further comprising a proximity sensor, wherein the proximity sensor is configured to sense a distance of travel of the translatable shaft.
13. 13. A method for detecting a time of use of a medication delivery pen, the method comprising: Receiving a medication delivery pen into a receiving chamber, the receiving chamber being defined by a side wall of a cover sleeve; engaging a translatable shaft within the channel to travel from a first position to at least a second position to toggle a switch in the electronic circuit; Storing the time of the last toggle switch; And The time elapsed since the last toggle switch is calculated.
14. 14. The method of claim 13, wherein the electronic circuit transmits an electronic signal to a processor after the translatable shaft toggles the switch.
15. 15. The method of claim 13, wherein the method comprises: transmitting the time of the last toggle switch to a remote user interface; the time of the last toggle switch is displayed.
16. 16. A system, comprising: A cap for a medication delivery pen, the cap comprising a piston detector mechanism, wherein the piston detector mechanism comprises: A channel extending from the outer surface to the inner surface, At least one switch; A translatable shaft disposed at least partially in the channel, wherein the translatable shaft is oriented to travel from a first position to at least a second position to toggle the at least one switch; an analyte sensor system in wireless communication with the cap sleeve, and A remote user interface in wireless communication with the cover sleeve.
17. 17. The system of claim 16, wherein the remote user interface is in wireless communication with a cloud.
18. 18. The system of claim 16, wherein the wireless communication between the remote user interface and the cover comprises communicating a time when the switch was recently toggled and at least one reading from the analyte sensor system to the remote user interface, and setting or updating a treatment parameter.
19. 19. The system of claim 17, wherein the wireless communication between the remote user interface and the cloud comprises reporting a time when the switch was last toggled and at least one reading from the analyte sensor system to the cloud for at least one analysis, updating treatment parameters.
20. 20. A system, comprising: A cap for a medication delivery pen, the cap comprising a piston detector mechanism, wherein the piston detector mechanism comprises: A channel extending from the outer surface to the inner surface, At least one switch; A translatable shaft disposed at least partially in the channel, wherein the translatable shaft is oriented to travel from a first position to at least a second position to toggle the at least one switch, and A remote user interface in wireless communication with the cover sleeve.

Description

Treatment devices, methods, and systems including a piston detector The application is filed 5/2019 and is named as a treatment device, a treatment method and a treatment system comprising a piston type detector, and is a divisional application of China patent application with the application number 201910368706.6. Technical Field The invention relates to a device, a method and a system comprising a piston detector. In certain embodiments, the piston detector may be located within a cap sleeve of a dosing device, such as a drug delivery pen. The devices, methods and systems provided herein may collect time data regarding the removal and/or replacement of a cap from a dosing device, which may thereby be used to determine treatment settings and/or treatment recommendations. Background Diabetes is a chronic metabolic disorder disease in which the human body cannot normally absorb sugar due to insufficient insulin secretion. This insulin hyposecretion leads to hyperglycemia, i.e. the presence of excess glucose in the plasma. Long-term hyperglycemia can lead to a variety of severe symptoms as well as life threatening long-term complications such as dehydration, ketoacidosis, diabetic coma, cardiovascular disease, chronic renal failure, retinal damage, and nerve damage and its attendant amputation risk. Typical methods of treating diabetes are blood glucose self-monitoring and insulin self-administration. However, the "correct" dose of insulin varies with the glucose content in the blood. Insufficient insulin doses can lead to hyperglycemia, while excessive insulin doses can lead to hypoglycemia. Hypoglycemia can lead to clumsiness, difficulty speaking, confusion, loss of consciousness, seizures, or death. Thus, diabetics (PWD) face a considerable cognitive burden in determining whether insulin dosage is appropriate. Collecting treatment data for PWDs can be used to improve treatment decisions, so reliable and powerful data collection tools are needed. Disclosure of Invention In one embodiment, a cover for a medication delivery pen includes a piston detector mechanism. The piston detector mechanism includes at least one inner housing having a first open end through which the drug delivery pen is insertable, a second end opposite the first end, a sidewall defined by an outer surface and an opposite inner surface, and a channel extending from the outer surface to the inner surface. The sidewall extends between the first end and the second end, thereby defining a pen receiving chamber therebetween. The piston detector mechanism further includes at least one switch and a translatable shaft disposed at least partially in the channel. The translatable shaft includes a body extending from at least a pen engagement portion in the pen receiving chamber to a switch engagement portion in the pen receiving chamber. The translatable shaft is oriented to travel from a first position to at least a second position to toggle the at least one switch during capping of a medication delivery pen into the inner housing. In one embodiment, a capping method for detecting a drug delivery pen includes capping a drug delivery pen into the cap sleeve containing the piston detector mechanism, and during capping, imparting movement of the drug delivery pen to the translatable shaft of the piston detector mechanism such that the switch engagement portion interacts with the switch to cause toggling of the switch. In one embodiment, a system includes the cap housing containing the piston detector mechanism, an analyte sensor system in communication with the cap housing, wherein the analyte sensor includes a blood glucose meter, a dynamic glucose monitor, or a continuous glucose monitor, and a mobile computing device capable of wireless communication with the cap housing. Additional advantages of embodiments will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the embodiments. The advantages of the invention may be realized and attained by means of the elements in the instrumentalities indicated in the appended claims. The foregoing discussion and the following detailed description are merely examples and are thus not intended to limit the scope of the claims, as claimed. Drawings The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description, serve to explain the principles of the disclosure of the patent application. FIG. 1A illustrates a diabetes management system that may include embodiments described herein including a cap, an insulin injection pen, a glucose sensor, and a mobile device. FIG. 1B shows how a PWD uses a glucose sensor on an arm to detect the blood glucose content of the PWD, and how a user obtains data from the glucose sensor using a cap that has been secured to a fast acting insulin pen, including embodiments of caps as described