CN-121987199-A - Near infrared brain function detection method, device, equipment and medium

CN121987199ACN 121987199 ACN121987199 ACN 121987199ACN-121987199-A

Abstract

A near infrared detection method, device, equipment and medium for brain function relates to the field of brain information acquisition. The method comprises the steps of generating an initial phase control parameter set based on target detection depth, driving a target annular array to emit near infrared light to reach a target detection point, generating an actual signal quality value based on phase delay data of a first return light signal, determining the initial phase control parameter set as a final phase control parameter set if the actual signal quality value is larger than or equal to a preset signal quality threshold value, correcting the initial phase control parameter set if the actual signal quality value is smaller than the preset signal quality threshold value, driving the target annular array until the actual signal quality value is larger than or equal to the preset signal quality threshold value, determining the current phase control parameter set as a final phase control parameter set, receiving a second return light signal of the target detection point, and calculating brain tissue blood oxygen parameters. By implementing the technical scheme provided by the application, the accuracy of detecting the deep brain function activities can be improved.

Inventors

GAO TIECHENG
DUAN HONGFENG
LIN JINXUAN

Assignees

北京心灵方舟科技发展有限公司

Dates

Publication Date: 20260508
Application Date: 20260410

Claims (10)

1. A near infrared brain function detection method, comprising: Generating an initial phase control parameter set based on the target detection depth; Driving a target annular array to emit near infrared light to a target detection point of the target detection depth based on the initial phase control parameter set, wherein the target annular array comprises an annular array or a plurality of annular arrays, and the annular arrays comprise a plurality of VCSEL light source units; receiving and analyzing a first return light signal of the target detection point; Generating an actual signal quality value corresponding to the first return optical signal based on the phase delay data of the first return optical signal; If the actual signal quality value is greater than or equal to a preset signal quality threshold, determining the initial phase control parameter set as a final phase control parameter set; If the actual signal quality value is smaller than the preset signal quality threshold value, calculating a difference value between the preset signal quality threshold value and the actual signal quality value; Correcting the initial phase control parameter set based on the difference value to obtain a corrected phase control parameter set; Driving the target annular array to emit near infrared light based on the corrected phase control parameter set and generating a corresponding actual signal quality value until the actual signal quality value is greater than or equal to the preset signal quality threshold value, and determining a current phase control parameter set as the final phase control parameter set; Receiving a second return light signal for the target detection point based on the final phase control set parameter; And calculating the brain tissue blood oxygen parameter of the target detection depth based on the amplitude attenuation data and the phase delay data of the second return light signal.
2. The method of claim 1, wherein generating an initial set of phase control parameters based on a target detection depth comprises: acquiring the space position coordinates of each VCSEL light source unit; Calculating a plurality of geometric propagation paths from each VCSEL light source unit to the target detection point based on the space position coordinates and the target detection depth; And extracting standard phase delay values corresponding to the geometric propagation paths based on a preset data corresponding table to obtain the initial phase control parameter set.
3. The method of claim 2, wherein driving a target annular array to emit near infrared light to a target detection point of the target detection depth based on the initial set of phase control parameters comprises: Converting each standard phase delay value in the initial phase control parameter set into a corresponding phase modulation current value according to a preset current value conversion table; Adding each phase modulation current value with a preset standard bias current value to obtain a total current value corresponding to each VCSEL light source unit; Based on each of the total current values, each of the VCSEL light source units is driven to emit near infrared light so that the near infrared light reaches the target detection point at the same time.
4. A method according to claim 3, wherein said converting each of said standard phase delay values in said initial phase control parameter set into a corresponding phase modulation current value according to a preset current value conversion table, comprises: Determining a lower limit phase point and an upper limit phase point surrounding the standard phase delay value based on the preset current value conversion table; extracting a lower limit current value corresponding to the lower limit phase point and an upper limit current value corresponding to the upper limit phase point; and obtaining the phase modulation current value by adopting a linear interpolation algorithm based on the relative position of the standard phase delay value between the lower limit phase point and the upper limit phase point.
5. The method of claim 1, wherein the generating an actual signal quality value of the phase delay in the first return optical signal based on the phase delay data of the first return optical signal comprises: continuously collecting phase delay data of the first return optical signal in a preset time window to obtain a phase delay data sequence; And calculating the variance of the phase delay data sequence, and taking the reciprocal of the variance as the actual signal quality value.
6. The method of claim 1, wherein after receiving the second return light signal for the target detection point based on the final phase control set parameter, the method further comprises: adding preset adjustment parameters into the final phase control set parameters, wherein the preset adjustment parameters are used for driving the target annular array to detect a longitudinal region of a preset depth range taking the target detection depth as a median value; receiving return light signals corresponding to all target detection points in the preset depth range; based on each of the return optical signals, a longitudinal brain tissue blood oxygen parameter profile is generated, the longitudinal brain tissue blood oxygen parameter profile being used to analyze the structure of blood oxygen changes.
7. The method of claim 1, wherein the near-infrared light comprises a plurality of near-infrared light of different wavelengths, and wherein calculating the brain tissue blood oxygen parameter for the target detection depth based on the amplitude attenuation data and the phase delay data of the second return light signal comprises: determining an average path length for the near infrared light to propagate within brain tissue based on the phase delay data; Extracting light absorption indexes corresponding to near infrared light with a plurality of wavelengths in the amplitude attenuation data based on the average optical path length; decomposing each light absorption index to obtain the concentration of oxyhemoglobin and the concentration of deoxyhemoglobin at the target detection depth; and using the oxyhemoglobin concentration and the deoxyhemoglobin concentration as blood oxygen parameters of the brain tissue.
8. A near infrared brain function detection device, comprising: The parameter generation module is used for generating an initial phase control parameter set based on the target detection depth; The near infrared light emitting module is used for driving a target annular array to emit near infrared light to a target detection point of the target detection depth based on the initial phase control parameter set, wherein the target annular array comprises an annular array or a plurality of annular arrays, and the annular arrays comprise a plurality of VCSEL light source units; The first receiving signal module is used for receiving and analyzing a first return light signal of the target detection point; The signal quality calculation module is used for generating an actual signal quality value corresponding to the first return optical signal based on the phase delay data of the first return optical signal; the first judging module is used for determining the initial phase control parameter set as a final phase control parameter set if the actual signal quality value is greater than or equal to a preset signal quality threshold value; The second judging module is used for calculating the difference value between the preset signal quality threshold value and the actual signal quality value if the actual signal quality value is smaller than the preset signal quality threshold value, correcting the initial phase control parameter set based on the difference value to obtain a corrected phase control parameter set, driving the target annular array to emit near infrared light based on the corrected phase control parameter set and generating a corresponding actual signal quality value until the actual signal quality value is larger than or equal to the preset signal quality threshold value, and determining the current phase control parameter set as the final phase control parameter set; A second receiving signal module for receiving a second return light signal of the target detection point based on the final phase control set parameter; and the detection result calculation module is used for calculating and obtaining the brain tissue blood oxygen parameter of the target detection depth based on the amplitude attenuation data and the phase delay data of the second return light signal.
9. An electronic device comprising a memory for storing instructions, a processor for executing the instructions stored in the memory to cause the electronic device to perform the method of any one of claims 1 to 7, a user interface, and a network interface, both for communicating with other devices.
10. A computer readable storage medium storing instructions which, when executed, perform the method of any one of claims 1 to 7.

Description

Near infrared brain function detection method, device, equipment and medium Technical Field The application relates to the field of brain information acquisition, in particular to a near infrared detection method, device, equipment and medium for brain functions. Background Near infrared spectroscopy (NIRS) technology, as a noninvasive, portable and high time resolution brain function monitoring tool, indirectly reflects the state of activity of neurons by measuring changes in hemoglobin concentration in local brain tissue caused by brain activity. The technology has great application potential in the fields of cognitive science research, clinical medical diagnosis, brain-computer interfaces and the like. The existing near-infrared brain function detection technology is mainly a continuous wave technology, is the most popular because of simple equipment and low cost, emits near-infrared light with constant intensity, and can only measure the total attenuation of light, so that the attenuation of light in tissues caused by absorption effect and scattering effect cannot be quantitatively separated, the measurement accuracy is limited, the optical characteristics of deep brain tissues are difficult to accurately obtain, and the accuracy of detecting deep brain function activities is limited. Disclosure of Invention The embodiment of the application provides a near infrared brain function detection method, device, equipment and medium, which are used for solving the technical problem of how to improve the accuracy of detecting deep brain function activities. The technical scheme of the embodiment of the application is realized as follows: in a first aspect, an embodiment of the present application provides a near infrared detection method for brain functions, including: Generating an initial phase control parameter set based on the target detection depth; Driving a target annular array to emit near infrared light to a target detection point of the target detection depth based on the initial phase control parameter set, wherein the target annular array comprises an annular array or a plurality of annular arrays, and the annular arrays comprise a plurality of VCSEL light source units; receiving and analyzing a first return light signal of the target detection point; Generating an actual signal quality value corresponding to the first return optical signal based on the phase delay data of the first return optical signal; If the actual signal quality value is greater than or equal to a preset signal quality threshold, determining the initial phase control parameter set as a final phase control parameter set; If the actual signal quality value is smaller than the preset signal quality threshold value, calculating a difference value between the preset signal quality threshold value and the actual signal quality value; Correcting the initial phase control parameter set based on the difference value to obtain a corrected phase control parameter set; Driving the target annular array to emit near infrared light based on the corrected phase control parameter set and generating a corresponding actual signal quality value until the actual signal quality value is greater than or equal to the preset signal quality threshold value, and determining a current phase control parameter set as the final phase control parameter set; Receiving a second return light signal for the target detection point based on the final phase control set parameter; And calculating the brain tissue blood oxygen parameter of the target detection depth based on the amplitude attenuation data and the phase delay data of the second return light signal. Optionally, the generating an initial phase control parameter set based on the target detection depth includes obtaining a spatial position coordinate of each VCSEL light source unit, calculating a plurality of geometric propagation paths from each VCSEL light source unit to the target detection point based on the spatial position coordinate and the target detection depth, and extracting a standard phase delay value corresponding to each geometric propagation path based on a preset data correspondence table to obtain the initial phase control parameter set. The method comprises the steps of converting each standard phase delay value in an initial phase control parameter set into a corresponding phase modulation current value according to a preset current value conversion table, adding each phase modulation current value and a preset standard bias current value to obtain a total current value corresponding to each VCSEL light source unit, and driving each VCSEL light source unit to emit near infrared light based on each total current value so that the near infrared light reaches the target detection point simultaneously. Optionally, the converting each standard phase delay value in the initial phase control parameter set into a corresponding phase modulation current value according to a preset current value