CN-121987230-A - Sensitivity determination method and device for imaging system, imaging system and storage medium

CN121987230ACN 121987230 ACN121987230 ACN 121987230ACN-121987230-A

Abstract

The application is applicable to the technical field of computers and provides a sensitivity determination method, a device, an imaging system and a storage medium of an imaging system, wherein the method comprises the steps of performing simulation processing on a plurality of different first setting combinations when detecting that the scattering effect of a scanning object of the imaging system meets a setting condition to obtain respective simulation sensitivity of each first setting combination; and obtaining a target sensitivity function of the imaging system based on each simulation sensitivity and each measured sensitivity. Compared with the prior art, the method can combine each simulation sensitivity and actual measurement sensitivity to obtain an accurate sensitivity function of the imaging system, so that the system sensitivity of each combination of different nuclides and collimators can be accurately determined according to the function, namely, the combination of all nuclides and collimators can be covered, and the accuracy of the determination of the sensitivity of the SPECT system under the combination of various nuclides and collimators is improved.

Inventors

TANG SONGSONG
Wang Beien
LIU ZHONGZHI
DONG JUN

Assignees

上海联影医疗科技股份有限公司

Dates

Publication Date: 20260508
Application Date: 20241108

Claims (10)

1. A method of determining sensitivity of an imaging system, the method comprising: When detecting that the scattering effect of a scanning object of an imaging system meets a set condition, performing simulation processing on a plurality of first set combinations to obtain respective simulation sensitivity of each first set combination, wherein each first set combination comprises a set formed by different sets of set collimators and set nuclides; acquiring the respective measured sensitivity of a plurality of second setting combinations, wherein each second setting combination is one of the plurality of first setting combinations; And obtaining a target sensitivity function of the imaging system based on each simulation sensitivity and each measured sensitivity.
2. The method of determining sensitivity of an imaging system according to claim 1, wherein said obtaining a target sensitivity function of said imaging system based on each of said simulated sensitivities and each of said measured sensitivities comprises: Obtaining an initial sensitivity function based on each simulation sensitivity; And adjusting the initial sensitivity function based on each measured sensitivity to obtain the target sensitivity function.
3. The method of determining sensitivity of an imaging system according to claim 2, wherein said deriving an initial sensitivity function based on each of said simulated sensitivities comprises: Performing curve fitting treatment on each simulation sensitivity to obtain a sensitivity curve; the initial sensitivity function is determined based on the sensitivity curve.
4. The method of determining sensitivity of an imaging system according to claim 2, wherein said deriving an initial sensitivity function based on each of said simulated sensitivities comprises: And inputting each simulation sensitivity to a trained sensitivity function construction model for processing to obtain the initial sensitivity function.
5. The method of determining sensitivity of an imaging system according to claim 2, wherein said adjusting said initial sensitivity function based on each of said measured sensitivities to obtain said target sensitivity function comprises: acquiring parameter information corresponding to each module in a simulation system corresponding to the imaging system in a simulation environment; Determining an adjustment mode of the initial sensitivity function based on each measured sensitivity and difference information between parameter information of each module and equipment parameters of each module in the imaging system; and adjusting the initial sensitivity function based on the adjustment mode to obtain the target sensitivity function.
6. The method of determining sensitivity of an imaging system according to claim 2, wherein said adjusting said initial sensitivity function based on each of said measured sensitivities to obtain said target sensitivity function comprises: Determining the target simulation sensitivity corresponding to each target combination which is the same as the second set combination of the measured sensitivity according to the initial sensitivity function; calculating an adjustment factor according to each target simulation sensitivity and each measured sensitivity; and adjusting the initial sensitivity function based on the adjustment factor to obtain the target sensitivity function.
7. The method of sensitivity determination of an imaging system according to any one of claims 1 to 6, wherein the method further comprises: when the scattering effect is detected to be not in accordance with the set condition, acquiring a collimator sensitivity formula, a sensitivity formula of a detector in the imaging system and a nuclide branch ratio; And constructing and obtaining the target sensitivity function based on the collimator sensitivity formula, the detector sensitivity formula and the nuclide branch ratio.
8. A sensitivity determining apparatus of an imaging system, comprising The simulation unit is used for performing simulation processing on a plurality of first setting combinations when detecting that the scattering effect of a scanning object of the imaging system meets a setting condition to obtain respective simulation sensitivity of each first setting combination, wherein each first setting combination comprises a set formed by different groups of setting collimators and setting nuclides; a first acquisition unit configured to acquire respective measured sensitivities of a plurality of second setting combinations, each of the second setting combinations being one of the plurality of first setting combinations; And the first function determining unit is used for obtaining a target sensitivity function of the imaging system based on each simulation sensitivity and each measured sensitivity.
9. An imaging system comprising a memory, a processor and a computer program stored in the memory and executable on the processor, wherein the processor implements the sensitivity determination method of the imaging system according to any one of claims 1 to 7 when executing the computer program.
10. A computer-readable storage medium storing a computer program, characterized in that the computer program, when executed by a processor, implements the sensitivity determination method of the imaging system according to any one of claims 1 to 7.

Description

Sensitivity determination method and device for imaging system, imaging system and storage medium Technical Field The application belongs to the technical field of computers, and particularly relates to a sensitivity determination method and device of an imaging system, the imaging system and a storage medium. Background In a common Single Photon Emission Computed Tomography (SPECT) system, for a particular clinical application, a particular nuclear species, drug, and corresponding collimator are used. In practice, if accurate quantitative SPECT image is required, the sensitivity of the SPECT system at various combinations of nuclides and collimators must be accurately determined. However, in the prior art, the system sensitivity of the SPECT system is generally estimated by an empirical formula, and since the empirical formula is generally implemented under ideal conditions, it is difficult to satisfy the actual requirements, and all combinations of nuclides and collimators cannot be covered, so that the accuracy of determining the sensitivity of the SPECT system under the combinations of the various nuclides and collimators is reduced. Disclosure of Invention The embodiment of the application provides a sensitivity determining method and device of an imaging system, the imaging system and a storage medium, which are used for solving the problem that the combination of all nuclides and collimators cannot be covered in the prior art, so that the accuracy of determining the sensitivity of a SPECT system under the combination of various nuclides and collimators is reduced. In a first aspect, an embodiment of the present application provides a method for determining sensitivity of an imaging system, including: When detecting that the scattering effect of a scanning object of an imaging system meets a set condition, performing simulation processing on a plurality of first set combinations to obtain respective simulation sensitivity of each first set combination, wherein each first set combination comprises a set formed by different sets of set collimators and set nuclides; acquiring the respective measured sensitivity of a plurality of second setting combinations, wherein each second setting combination is one of the plurality of first setting combinations; And obtaining a target sensitivity function of the imaging system based on each simulation sensitivity and each measured sensitivity. According to the sensitivity determination method of the imaging system, when the scattering effect of the scanning object of the imaging system is detected to meet the set condition, simulation processing is conducted on the plurality of first set combinations to obtain simulation sensitivity corresponding to each first set combination, actual measurement sensitivity of the plurality of second set combinations is obtained, and the target sensitivity function of the imaging system is obtained based on the simulation sensitivity and the actual measurement sensitivity. Compared with the prior art that the system sensitivity of the combination of partial nuclides and collimators can only be determined according to an empirical formula under ideal conditions, the method considers the influence of scattering effect on the system sensitivity, and under the condition that the scattering effect meets set conditions, the method can combine each simulation sensitivity and actual measurement sensitivity to obtain an accurate sensitivity function of an imaging system, so that the system sensitivity of the combination of different nuclides and collimators can be accurately determined according to the function, namely the combination of all nuclides and collimators can be covered, and the determination accuracy of the sensitivity of the SPECT system under the combination of various nuclides and collimators is improved. Meanwhile, because some nuclides are difficult to obtain in practical application, the method of experimental actual measurement is difficult to fully use, and the combination of nuclides and collimators is too many, so that the actual measurement cost is too high. In a possible implementation manner of the first aspect, obtaining the target sensitivity function of the imaging system based on each of the simulated sensitivities and each of the measured sensitivities includes: Obtaining an initial sensitivity function based on each simulation sensitivity; And adjusting the initial sensitivity function based on each measured sensitivity to obtain the target sensitivity function. In the above embodiment, the imaging system may adjust the sensitivity function determined by the simulation sensitivity based on the actually measured sensitivity, so as to obtain a more accurate target sensitivity function, thereby improving the accuracy of the subsequently determined system sensitivity. In an implementation manner of the first aspect, obtaining an initial sensitivity function based on each of the simulation sensitivities includes: Pe