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CN-121987483-A - Constant-temperature self-heating traditional Chinese medicine acupoint application and preparation method thereof

CN121987483ACN 121987483 ACN121987483 ACN 121987483ACN-121987483-A

Abstract

The invention discloses a constant-temperature self-heating traditional Chinese medicine acupoint application and a preparation method thereof, and belongs to the technical field of medical supplies. The traditional Chinese medicine acupoint application comprises an outermost layer, a heating layer, an adhesive layer, a medicine layer and release paper, wherein the heating layer is formed by uniformly coating constant-temperature self-heating materials, the medicine layer comprises an anti-seepage ring arranged on the adhesive layer, a positioning ring matched with the anti-seepage ring and a traditional Chinese medicine preparation, the traditional Chinese medicine preparation is traditional Chinese medicine gel or traditional Chinese medicine ointment, and the constant-temperature self-heating materials comprise, by mass, 10-20 parts of reduced iron powder, 0.5-3 parts of vermiculite, 1-5 parts of activated carbon, 0.5-3 parts of sodium chloride, 0.1-2 parts of poly-N-isopropyl acrylamide, 0.1-2 parts of carboxypropyl methyl cellulose and 5-10 parts of water. The traditional Chinese medicine acupoint application provided by the invention can stably maintain a proper temperature for a long time, promote transdermal absorption of traditional Chinese medicine components, enhance the stimulation effect on the acupoints and improve the treatment effect.

Inventors

  • JIN YONGMEI
  • SONG LIFANG

Assignees

  • 上海市第七人民医院(上海中医药大学附属第七人民医院)

Dates

Publication Date
20260508
Application Date
20260120

Claims (7)

  1. 1. The constant-temperature self-heating material is characterized by comprising, by mass, 10-20 parts of reduced iron powder, 0.5-3 parts of vermiculite, 1-5 parts of activated carbon, 0.5-3 parts of sodium chloride, 0.1-2 parts of poly-N-isopropyl acrylamide, 0.1-2 parts of carboxypropyl methyl cellulose and 5-10 parts of water.
  2. 2. The constant temperature self-heating material according to claim 1, wherein the constant temperature self-heating material comprises, by mass, 12 parts of reduced iron powder, 2.5 parts of vermiculite, 2 parts of activated carbon, 1 part of sodium chloride, 0.3 part of poly-N-isopropyl acrylamide, 0.2 part of hydroxypropyl methylcellulose and 6.5 parts of water.
  3. 3. A method for preparing a constant temperature self-heating material according to claim 1 or 2, comprising the steps of: Firstly, raw materials of reduced iron powder, vermiculite, activated carbon, sodium chloride, poly-N-isopropyl acrylamide, carboxypropyl methyl cellulose and water are weighed according to the proportion; step two, putting reduced iron powder, poly-N-isopropyl acrylamide and carboxypropyl methyl cellulose into a stirrer, uniformly mixing at the rotating speed of 10-50 rpm for 30-50 minutes to obtain a mixture 1; Stirring and mixing sodium chloride and water uniformly at the rotating speed of 10-50 rpm for 20 minutes to obtain a mixture 2; adding vermiculite and activated carbon into the mixture 1, and uniformly mixing to obtain a mixture 3; And fifthly, adding the mixture 2 into the mixture 3, and rapidly and uniformly stirring.
  4. 4. A constant temperature self-heating traditional Chinese medicine acupoint application is characterized by sequentially comprising an outermost layer, a heating layer, an adhesive layer, a medicine layer and release paper from outside to inside, wherein: the heating layer is formed by uniformly coating and curing the constant-temperature self-heating material according to claim 1 or 2; The medicine layer comprises an anti-seepage ring arranged on the adhesive layer, a positioning ring matched with the anti-seepage ring and a traditional Chinese medicine preparation, wherein the traditional Chinese medicine preparation is arranged in an area surrounded by the anti-seepage ring, the positioning ring and the release paper; the Chinese medicinal preparation is a Chinese medicinal gel or Chinese medicinal ointment.
  5. 5. The constant temperature self-heating traditional Chinese medicine acupoint application according to claim 4, wherein the traditional Chinese medicine preparation is traditional Chinese medicine gel, and the preparation step comprises the following steps of: (I) Extracting the traditional Chinese medicine with ethanol, and sequentially carrying out suction filtration, rotary evaporation, concentration and vacuum drying to obtain traditional Chinese medicine extract powder; (II) adding the traditional Chinese medicine extract powder into CMC-Na solution according to the mass concentration of 1% -10%, and uniformly stirring to obtain mixed solution; And (III) placing the mixed gel in a vacuum drying oven, standing at room temperature under vacuum to perform defoaming treatment, uniformly coating the mixed gel on medical non-woven fabrics, standing at room temperature, standing until the gel is primarily solidified and shaped, and performing ultraviolet sterilization to obtain the medical gel.
  6. 6. The constant temperature self-heating traditional Chinese medicine acupoint application according to claim 4, wherein the traditional Chinese medicine preparation is a traditional Chinese medicine ointment, and the preparation method comprises the steps of heating vaseline to be molten with small fire, adding the traditional Chinese medicine powder, rapidly stirring to enable the traditional Chinese medicine powder to be fully and uniformly mixed with the vaseline, adding honey after the mixed liquid is cooled, stirring again uniformly, naturally cooling and solidifying to obtain the application ointment, smearing on medical gauze or medical non-woven fabric, fixing with an adhesive tape, and sterilizing with ultraviolet to obtain the traditional Chinese medicine ointment.
  7. 7. The method for preparing the constant temperature self-heating traditional Chinese medicine acupoint application according to any one of claims 4-6, which is characterized by comprising the following steps: (1) Placing the constant temperature self-heating material on the inner side of the fixing belt, and fixing an adhesive layer on the constant temperature self-heating material; (2) And placing the traditional Chinese medicine preparation in an area surrounded by the anti-seepage ring and the positioning ring, covering release paper on the anti-seepage ring and the positioning ring, and then integrally fixing the anti-seepage ring and the positioning ring on the adhesive layer.

Description

Constant-temperature self-heating traditional Chinese medicine acupoint application and preparation method thereof Technical Field The invention belongs to the technical field of medical products, and particularly relates to a constant-temperature self-heating traditional Chinese medicine acupoint application and a preparation method thereof. Background In the theory of traditional Chinese medicine, the acupoint application therapy is an important external therapy, and the purposes of treating diseases, preventing and protecting health are achieved by applying the medicine to specific acupoints. At present, various acupoint plaster products exist on the market, but some problems generally exist. For example, some acupoint patches have no heating effect, the medicine has poor diffusion effect as the effect after heating, the medicine effect lasts for a short time, the medicine effect cannot be fully exerted, and some products are not ideal in temperature control, or the skin is scalded due to the fact that the heating temperature is too high, or the acupoint cannot be continuously stimulated due to the fact that the heating time is too short. In addition, the traditional acupoint plaster is mainly prepared by mixing traditional Chinese medicines with hot melt adhesive, and in the process of heating the hot melt adhesive to a melting point, the high temperature can decompose or lose activity of part of heat-sensitive traditional Chinese medicine components, so that the efficacy is affected. Meanwhile, the hot melt adhesive has relatively tight texture after solidification, the diffusion speed of the medicine in the hot melt adhesive can be slow, the release amount of the medicine at different positions can be different, so that the medicine is released unevenly, part of the hot melt adhesive material can also stimulate the skin, especially sensitive skin crowds, and allergic reactions such as redness, itching and the like can occur after the hot melt adhesive is used. Therefore, the existing drug layer has to be improved in terms of retention rate of drug effect, affinity of components to skin, transdermal absorption efficiency, etc. For the acupoint plaster containing traditional Chinese medicine components, how to better exert the efficacy of the traditional Chinese medicine and combine with stable temperature control so as to improve the overall curative effect of the acupoint plaster is a problem which needs to be solved at present. Disclosure of Invention Aiming at the defects existing in the prior art, the main purpose of the invention is to provide a constant-temperature self-heating traditional Chinese medicine acupoint application, which can stably maintain proper temperature for a long time, promote transdermal absorption of traditional Chinese medicine components, enhance the stimulation effect on acupoints, improve the treatment effect, simultaneously have good skin affinity and reduce the stimulation on skin. The invention further aims at providing a preparation method of the constant-temperature self-heating traditional Chinese medicine acupoint application, which is simple in process and easy for large-scale production. In order to achieve the above purpose, the invention adopts the following technical scheme: The invention provides a constant-temperature self-heating material which comprises, by mass, 10-20 parts of reduced iron powder, 0.5-3 parts of vermiculite, 1-5 parts of activated carbon, 0.5-3 parts of sodium chloride, 0.1-2 parts of poly-N-isopropyl acrylamide, 0.1-2 parts of carboxypropyl methyl cellulose and 5-10 parts of water. Preferably, the constant temperature self-heating material further comprises water absorbing resin, and one or more of sodium polyacrylate, polyacrylamide and polyvinyl alcohol are selected. Preferably, the constant temperature self-heating material comprises 12 parts of reduced iron powder, 2.5 parts of vermiculite, 2 parts of activated carbon, 1 part of sodium chloride, 0.3 part of poly N-isopropyl acrylamide, 0.2 part of hydroxypropyl methyl cellulose and 6.5 parts of water in parts by weight. In a second aspect of the present invention, there is provided a method for preparing the constant temperature self-heating material comprising the steps of: Firstly, raw materials of reduced iron powder, vermiculite, activated carbon, sodium chloride, poly-N-isopropyl acrylamide, carboxypropyl methyl cellulose and water are weighed according to the proportion; step two, putting reduced iron powder, poly-N-isopropyl acrylamide and carboxypropyl methyl cellulose into a stirrer, uniformly mixing at the rotating speed of 10-50 rpm for 30-50 minutes to obtain a mixture 1; Stirring and mixing sodium chloride and water uniformly at the rotating speed of 10-50 rpm for 20 minutes to obtain a mixture 2; adding vermiculite and active carbon into the mixture 1, and uniformly mixing to obtain a mixture 3; and fifthly, adding the mixture 2 into the mixture 3, and rapidly and unif