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CN-121987504-A - Plant starch soft capsule and preparation method thereof

CN121987504ACN 121987504 ACN121987504 ACN 121987504ACN-121987504-A

Abstract

The invention belongs to the technical field of capsule preparations, and relates to a plant starch soft capsule and a preparation method thereof. The plant starch soft capsule consists of hydroxypropyl starch, carrageenan, plantain seed gum, sodium alginate, sodium hyaluronate and meglumine. The preparation method comprises the steps of raw material pretreatment, mixing and glue making, vacuum degassing, soft capsule molding and drying. The soft capsule has excellent weather resistance through innovative raw material proportion and preparation process, can adapt to transportation and storage at extreme temperature, and meanwhile, the product takes plant source raw materials as a main material, eliminates fishy smell brought by gelatin, and improves use comfort and market acceptance. The plant starch soft capsule can be applied to the field of cosmetics and used as a carrier of an active ingredient.

Inventors

  • ZHU XIAOLONG
  • Wei Shisong

Assignees

  • 广州东智盟化妆品有限公司

Dates

Publication Date
20260508
Application Date
20260403

Claims (10)

  1. 1. The plant starch soft capsule is characterized by comprising, by weight, 55-75 parts of hydroxypropyl starch, 20-35 parts of carrageenan, 2-8 parts of psyllium seed gum, 1-5 parts of sodium alginate, 0.5-2 parts of sodium hyaluronate and 0.5-2 parts of meglumine.
  2. 2. The plant starch soft capsule of claim 1, wherein the plant starch soft capsule comprises the following components in parts by weight: 65 parts of hydroxypropyl starch, 30 parts of carrageenan, 5 parts of plantain seed gum, 3 parts of sodium alginate, 1.5 parts of sodium hyaluronate and 1 part of meglumine.
  3. 3. A method for preparing the plant starch soft capsule according to claim 1, which is characterized by comprising the following steps: (1) Raw material pretreatment, namely respectively crushing and sieving hydroxypropyl starch and carrageenan for standby, standing and swelling the psyllium seed gum in warm water, adding sodium hyaluronate and meglumine, and hydrating in stages to obtain a psyllium seed gum mixed solution for standby; (2) Mixing, namely heating purified water, respectively adding hydroxypropyl starch, a mixed solution of semen plantaginis gum, carrageenan and sodium alginate, and stirring and mixing uniformly; (3) Vacuum degassing treatment; (4) Molding the soft capsule; (5) And (5) drying.
  4. 4. The method for preparing a plant starch soft capsule according to claim 3, wherein the stepwise hydration is performed at a speed of 50 to 60 rpm for 20 to 40 minutes, at a speed of 80 to 100 rpm for 1 to 1.5 hours, and at a speed of 50 to 60 rpm for 1 to 2 hours.
  5. 5. The method for preparing a plant starch soft capsule according to claim 3, wherein the psyllium seed gum mixed solution is prepared by placing the psyllium seed gum in warm water at 30-40 ℃ which is 8-12 times the weight of the psyllium seed gum, standing for 1-1.5 hours, performing swelling treatment, adding sodium hyaluronate and meglumine for hydration in stages, stirring at 50-60 rpm for 20-40 minutes, then stirring at 80-100 rpm for 1-1.5 hours, and finally stirring at 50-60 rpm for 1-2 hours to obtain a uniform psyllium seed gum mixed solution.
  6. 6. The method for preparing a plant starch soft capsule according to claim 3, wherein the mixing and gel-making step comprises the steps of taking purified water which is 6-8 times the weight of hydroxypropyl starch, heating to 60-70 ℃ and maintaining, adding hydroxypropyl starch, stirring at a speed of 100-150 rpm for 15-20 minutes, adding the mixed solution of plantain seed gel, stirring at a speed of 100-150 rpm for 15-20 minutes, adding carrageenan, increasing the stirring speed to 150-200 rpm, stirring for 25-35 minutes, adding sodium alginate, and stirring at a speed of 150-200 rpm for 15-20 minutes to form a uniform colloidal solution.
  7. 7. The method for preparing a plant starch soft capsule according to claim 3, wherein the vacuum degassing step is to transfer the colloidal solution into a vacuum degassing apparatus and degas for 20-25 minutes under the condition that the vacuum degree is-0.08 to-0.09 MPa.
  8. 8. The method for preparing a plant starch soft capsule according to claim 3, wherein the soft capsule molding step is performed by using a rotary soft capsule press at a temperature of 40-50 ℃, a pressure of 0.5-1.5MPa, and a mold rotation speed of 2-4 rpm.
  9. 9. The method for preparing a plant starch soft capsule according to claim 3, wherein the drying temperature is controlled to be 25-30 ℃ and the relative humidity is controlled to be 30-40% in the drying step, and the plant starch soft capsule is dried to have a water content of 8-12%.
  10. 10. Use of the plant starch soft capsule of claim 1 in the cosmetic field.

Description

Plant starch soft capsule and preparation method thereof Technical Field The invention belongs to the technical field of capsule preparations, and particularly relates to a plant starch soft capsule and a preparation method thereof. Background The disclosure of this background section is only intended to increase the understanding of the general background of the invention and is not necessarily to be construed as an admission or any form of suggestion that this information forms the prior art already known to those of ordinary skill in the art. In the fields of medicines, foods, cosmetics and the like, soft capsules are widely used as an important packaging form, and the main function of the soft capsules is to cover various active ingredients. At present, the commercial soft capsule products still take gelatin as the main choice in terms of raw material preparation. However, gelatin, which is a material of animal origin, has many problems that are difficult to ignore. From the weather resistance point of view, soft capsules made of gelatin are inferior in weather resistance. In the transportation process, soft capsules can be softened, deformed and even adhered when being subjected to a high-temperature environment, and can become brittle and easily break under a low-temperature condition. For example, in hot summer days, when the temperature in the transport vehicle exceeds 40 ℃, the physical form of the gelatin soft capsule may change, severely affecting product quality. In addition, in cold winter, especially in northern areas, the outdoor temperature is often as low as-10 ℃, at this time, the brittleness of the gelatin soft capsules is significantly increased, the gelatin soft capsules are broken by a little careless in the process of carrying, great challenges are brought to the transportation and storage of products, and high transportation risks exist. In terms of odor, gelatin itself has a certain fishy smell, which makes soft capsules prepared from gelatin as a raw material also have an unpleasant fishy smell of gelatin. This smell can be emitted after the product is opened, greatly affecting the consumer's use experience. Especially for people with relatively sensitive smell, such as children, pregnant women and the like, the fishy smell of the gelatin can cause discomfort and even cause nausea and other adverse reactions, thereby reducing the market acceptance of the product. Chinese patent publication No. CN113121889a discloses a starch film-forming composition and its application in plant soft capsules. Specifically, the starch film-forming composition comprises 10-35wt% of hydroxypropyl starch, 8-25wt% of crosslinked starch, 10-30wt% of plasticizer and 20-50wt% of water, and can be combined with common auxiliary materials of soft capsules to prepare plant starch soft capsules according to the traditional soft capsule preparation process (batching-gelatin-pelleting-drying). The Chinese patent publication No. CN119632945A discloses a method for preparing composite soft capsule skin containing plant starch, wherein the composite soft capsule skin comprises, by mass, 15-30% of gelatin, 5-20% of modified plant starch, 1-15% of composite vegetable gum, 1-10% of dopamine grafted pullulan, 10-30% of plasticizer and 25-45% of solvent. In order to solve the above problems of the gelatin soft capsules, researches on the plant starch soft capsules related to the above patents are available, but the prior art still has obvious defects in improving weather resistance, and is difficult to meet the market demand for high quality soft capsule products. Disclosure of Invention The invention aims to solve the problems of poor weather resistance and the like of the existing gelatin soft capsule and provides a plant starch soft capsule and a preparation method thereof. The plant starch soft capsule disclosed by the invention is based on plant source raw materials, and the weather resistance of the soft capsule is obviously improved through innovative formula composition and preparation process, so that the market demand for high-quality soft capsule products is met. The plant starch soft capsule comprises the following components in parts by weight: 55-75 parts of hydroxypropyl starch, 20-35 parts of carrageenan, 2-8 parts of semen plantaginis gum, 1-5 parts of sodium alginate, 0.5-2 parts of sodium hyaluronate and 0.5-2 parts of meglumine. Wherein the preferable formula comprises 65 parts of hydroxypropyl starch, 30 parts of carrageenan, 5 parts of semen plantaginis gum, 3 parts of sodium alginate, 1.5 parts of sodium hyaluronate and 1 part of meglumine. The formula can construct a stable colloid network structure through the synergistic effect of the components, and improves the weather resistance and physical properties of the soft capsule. The preparation method of the plant starch soft capsule comprises the following steps: (1) The preparation method comprises the steps of raw material pretreatment, respect