CN-121987517-A - Composition with synergistic anti-saccharification effect and application thereof

Abstract

The invention relates to the technical field of cosmetics, in particular to a composition with synergistic anti-saccharification effect and application thereof. The composition comprises an A component, a B component and a C component, wherein the A component comprises adenosine, the B component comprises elmendocin and bisabolol, and the C component comprises decarboxylated carnosine hydrochloride. The composition of the invention contains adenosine + ectoine + bisabolol + decarboxylated carnosine hydrochloride, can solve the problems of single anti-saccharification component, single action mechanism of single repairing component and poor effect, realizes anti-saccharification and skin repairing synergy, and can systematically solve multiple problems of skin aging through a time sequence synergistic mechanism of 'internal energization-external defense-targeted removal', thereby realizing the three-in-one comprehensive skin care effect.

Inventors

• YANG ZHEN
• DING ZHIQIANG
• ZHU YIRUI
• SONG YANG

Assignees

• 上海中翊日化有限公司

Dates

Publication Date

20260508

Application Date

20260316

Claims (10)

1. 1. A composition with synergistic anti-glycation effect is characterized by comprising an A component, a B component and a C component, wherein the A component comprises adenosine, the B component comprises ectoin and bisabolol, and the C component comprises decarboxylated carnosine hydrochloride.
2. 2. The composition according to claim 1, wherein the composition comprises 0.001-0.5 parts by weight of adenosine, 0.001-2.0 parts by weight of ectoine, 0.001-0.2 parts by weight of bisabolol, and 0.001-1.0 parts by weight of decarboxylated carnosine hydrochloride.
3. 3. The composition of claim 2, wherein the C component further comprises carnosine, the carnosine being present in an amount of 0.001 to 1.0 parts by weight.
4. 4. A composition according to claim 3, wherein the adenosine is present in an amount of 0.01 to 0.2 parts by weight.
5. 5. A composition according to claim 3, wherein the elkedoxine is 0.01-0.5 parts by weight and the bisabolol is 0.01-0.5 parts by weight.
6. 6. A composition according to claim 3, wherein the decarboxylated carnosine hydrochloride is 0.5-1.0 parts by weight and carnosine is 0.01-0.5 parts by weight.
7. 7. The composition of claim 1, further comprising a D component comprising caffeine and nicotinamide, wherein the caffeine is present in an amount of 0.01-2 parts by weight and the nicotinamide is present in an amount of 0.01-2 parts by weight.
8. 8. The composition of any of claims 2-5, wherein the weight ratio of the a, B and C components is (0.01-0.2): 0.02-0.5): 0.1-1.
9. 9. The composition of claim 8 wherein the weight ratio of the A, B and C components is (0.01-0.1): 0.02-0.5): 0.1-1.
10. 10. Use of a composition according to claim 1, for the preparation of a cosmetic product, said composition being present in an amount of 0.1-10% by weight of the cosmetic product.

Description

Composition with synergistic anti-saccharification effect and application thereof Technical Field The invention relates to the technical field of cosmetics, in particular to a composition with synergistic anti-saccharification effect and application thereof. Background Along with the aging and external stimulation such as ultraviolet rays and pollution, the skin of a human body is easy to generate advanced glycation end products (AGEs) by glycation reaction, the problems of yellowing, looseness, wrinkling and the like of the skin are caused, meanwhile, the external stimulation can induce skin inflammation, promote the release of pro-inflammatory factors, exacerbate oxidative stress and further destroy skin barriers, and form malignant circulation of 'inflammation-glycation-barrier damage', so that the skin color is dark, rough and dull. Currently, the anti-glycation skin care products in the market are mainly divided into two types, one type uses single components such as carnosine and the like to competitively combine with glycosyl groups to inhibit the generation of AGEs, the other type uses antioxidant to neutralize free radicals to indirectly reduce glycation risks, and part of the products are added with anti-inflammatory components such as bisabolol, exendin and the like, but are only used as auxiliary components for adaptation of sensitive muscles and are not deeply fused with an anti-glycation system. The prior art has the defects of single action mechanism and lack of systematicness, only focuses on single link intervention of saccharification, does not combine cell energy metabolism, barrier defense and AGEs targeted elimination, ignores acceleration of inflammatory aging on saccharification, and has extremely poor synergistic effect. Chinese patent application CN113876610a discloses a skin care composition containing adenosine and ectoin, which focuses on improving cell energy and skin external defenses, and can enhance skin resistance to some extent. However, the patent only focuses on cell energization and basic barrier protection, does not construct a complete anti-inflammatory defense system, cannot realize targeted cleavage and elimination of formed AGEs, has key defects in defense and repair links, and cannot form a complete anti-saccharification closed loop. In conclusion, the prior art cannot realize the omnibearing anti-saccharification of 'prevention + repair + reversion', and is difficult to systematically solve the problems of skin saccharification, inflammation and metabolic disorder. Therefore, there is a need to develop a multi-dimensional synergistic anti-glycation composition to construct a complete anti-glycation system, so as to radically improve the aging problems such as skin dullness, yellowing and the like. Disclosure of Invention The invention provides a composition with synergistic anti-glycation effect, which comprises an A component, a B component and a C component, wherein the A component comprises adenosine, the B component comprises ectoin and bisabolol, and the C component comprises decarboxylated carnosine hydrochloride. The decarboxylated carnosine hydrochloride is 5-20wt% of decarboxylated carnosine hydrochloride water solution. The invention researches find that the composition formed by compounding adenosine, ectoin, bisabolol and decarboxylated carnosine hydrochloride can solve the problems of single anti-saccharification component, single action mechanism of single repairing component and poor effect, and realize anti-saccharification and skin repairing synergy. The invention further researches that the carnosine is further added on the basis, and can form double-targeting anti-sugar synergy with the decarboxylated carnosine hydrochloride, and the time sequence synergy mechanism of 'internal energization-external defense-targeted elimination' is constructed, so that multiple aging problems of skin saccharification, inflammation, relaxation, darkness and the like are systematically solved, and finally the comprehensive skin care effect of anti-sugar, anti-wrinkle and repair is realized. Optionally, the composition comprises 0.001-0.5 part of adenosine, 0.001-2.0 parts of ectoin, 0.001-0.2 parts of bisabolol and 0.001-1.0 part of decarboxylated carnosine hydrochloride in parts by weight. The component C also comprises carnosine, wherein the weight part of the carnosine is 0.001-1.0 part. Optionally, the composition further comprises a D component comprising caffeine and nicotinamide. Optionally, the adenosine is 0.01-0.2 parts by weight. Optionally, the weight parts of the ectoin are 0.01-0.5 part and the weight parts of the bisabolol are 0.01-0.5 part. Optionally, the decarboxylated carnosine hydrochloride is 0.5-1.0 parts by weight, and the carnosine is 0.01-0.5 parts by weight. Optionally, the caffeine is 0.01-2 parts by weight and the nicotinamide is 0.01-2 parts by weight. The weight ratio of the component A to the component B to the component C is (0.01-0