CN-121987524-A - Composition containing succinoglycan and application of succinoglycan in regulating and controlling liquid crystal lamellar phase repetition distance

Abstract

The invention relates to the technical field of cosmetic preparations, and discloses a composition containing succinoglycan and an application thereof in regulating and controlling the lamellar phase repetition distance of liquid crystals, wherein the composition contains a liquid crystal component and an effective amount of succinoglycan, the addition of the succinoglycan can effectively regulate the lamellar phase repetition distance of the liquid crystals in the composition and improve the thermal stability of the composition, the addition of the succinoglycan can cause the lamellar phase repetition distance of the liquid crystals to change by 6.2 to 19.4 percent through small angle X-ray scattering (SAXS), and the invention provides a novel method for accurately regulating and controlling the lamellar phase repetition distance of the liquid crystals of the cosmetic from a nanometer scale, and the obtained composition has better stability, moisture retention and skin feel during use.

Inventors

• ZHOU KANGFU
• SHANG YAZHUO
• YE CHUANJUN
• Qi Chaoling
• WANG FEIFEI
• MA XIAO
• GUO ZHENYU

Assignees

• 云南特色植物提取实验室有限公司
• 华东理工大学
• 云南贝泰妮生物科技集团股份有限公司

Dates

Publication Date

20260508

Application Date

20260212

Claims (10)

1. 1. A composition comprising a succinoglycan is characterized by comprising a liquid crystal component and a succinoglycan, wherein the addition of the succinoglycan is effective to adjust the lamellar phase repeat distance of the liquid crystal in the composition and to increase its thermal stability.
2. 2. A composition comprising succinoglycan as defined in claim 1, wherein said succinoglycan is added in an amount of 0.02% -0.5% by weight of the total mass of said composition, and the average molecular weight of said succinoglycan is not less than 1000000 daltons.
3. 3. A composition comprising succinoglycan as claimed in claim 1, wherein the liquid crystal component comprises an aqueous phase and an oil phase, the oil phase comprising 1% to 6% of an emulsifier and 5% to 60% of a lipid, the balance being the aqueous phase, based on the total mass of the composition.
4. 4. A composition comprising succinoglycan as defined in claim 3, wherein said emulsifier is an emulsifier capable of forming a layer-like liquid crystal phase.
5. 5. A composition comprising succinoglycan as defined in claim 1, wherein said composition is a cosmetic composition and said succinoglycan has an average molecular weight of 6000000 daltons.
6. 6. An application of succinoglycan in regulating the repetition distance of lamellar phase of liquid crystal is disclosed.
7. 7. The method of claim 6, wherein the succinoglycan is added to a liquid crystal composition comprising an emulsifier, a lipid and water.
8. 8. The method of claim 6, wherein the layer-like phase repeat distance d of the liquid crystal in the liquid crystal composition is changed by 6.2% to 19.4% as compared to before the application.
9. 9. The method of claim 6, wherein the thermal stability of the layered liquid crystal structure in the liquid crystal composition is improved by the application.
10. 10. Use of succinoglycan as a liquid crystal lamellar phase repeat distance modifier and/or a liquid crystal heat stabilizer.

Description

Composition containing succinoglycan and application of succinoglycan in regulating and controlling liquid crystal lamellar phase repetition distance Technical Field The invention relates to the technical field of cosmetic preparations, in particular to a composition containing succinyl glycan and application of the succinyl glycan in regulating and controlling the repetition distance of a liquid crystal lamellar phase. Background The liquid crystal structure can significantly improve the stability, moisture retention and active delivery efficiency of the product in cosmetics (such as emulsion and cream). At present, the liquid crystal phase is mainly constructed by screening specific types and proportions of emulsifying agents and grease. However, the ability of the prior art to precisely manipulate liquid crystal nanostructures is limited, and particularly to orient, predictably alter their periodic parameters (e.g., lamellar phase repeat distance of the liquid crystal), and to simultaneously promote their thermal stability remains a challenge. Commonly used thickening stabilizers (e.g., xanthan gum, carbomers, various synthetic polymers) primarily affect the macroscopic rheology of the system, often fail to specifically interact with the nano-periodic structure of the liquid crystal and may even interfere with the formation of the liquid crystal. Therefore, there is an urgent need for a composition containing succinoglycan and an application of succinoglycan in controlling the layered phase repetition distance of liquid crystal, which can intelligently adjust the nanostructure of the composition without damaging the basic phase state of the liquid crystal, thereby obtaining better product performance. Disclosure of Invention In view of the shortcomings of the prior art, the invention aims to provide a composition containing succinoglycan and application of the succinoglycan in regulating and controlling the layered phase repetition distance of liquid crystal. The invention aims to solve the technical problems that the nano periodic structure of the cosmetic liquid crystal composition is difficult to accurately regulate and control and the thermal stability of a liquid crystal phase is insufficient in the prior art. The scheme of the invention is as follows: A composition comprising a succinoglycan comprising a liquid crystal component and a succinoglycan, wherein the addition of said succinoglycan is effective to adjust the lamellar phase repeat distance of the liquid crystal in said composition and to increase its thermal stability. As a preferable technical scheme, the addition amount of the succinoglycan is 0.02% -0.5% of the total mass of the composition, and the average molecular weight of the succinoglycan is not less than 1000000 daltons. According to the preferable technical scheme, the liquid crystal component comprises an aqueous phase and an oil phase, wherein the oil phase comprises 1% -6% of emulsifying agent, 5% -60% of grease and the balance of the aqueous phase by the total mass of the composition. As a preferable technical scheme, the emulsifier is an emulsifier capable of forming a layer-shaped liquid crystal phase. As a preferred embodiment, the composition is a cosmetic composition and the succinoglycan has an average molecular weight of 6000000 daltons. The cosmetic composition is a moisturizing lotion, cream, essence or sunscreen product. The invention also discloses an application of succinoglycan in regulating and controlling the repetition distance of the lamellar phase of the liquid crystal. As a preferred embodiment, the succinoglycan is added to a liquid crystal composition comprising an emulsifier, a fat and water. As a preferable technical scheme, the application enables the lamellar phase repetition distance d value of the liquid crystal in the liquid crystal composition to change by 6.2% -19.4% compared with the value before application. According to SAXS assay data of the present invention, in example 1, the addition of 0.1% succinoglycan changes the lamellar phase repeat distance from about 26.8nm to about 25.1nm by about 6.2%. As a preferable technical scheme, the application improves the thermal stability of the layered liquid crystal structure in the liquid crystal composition. The invention also discloses application of the succinoglycan as a regulator of the layered phase repetition distance of the liquid crystal and/or a liquid crystal heat stabilizer. Compared with the prior art, the invention has the advantages that: Precise structural control, succinoglycan was found and demonstrated to be able to act as a "nanostructure regulator" predictably altering the lamellar phase repeat distance of the liquid crystal. This effect is not possessed by conventional thickening/stabilizing agents, and represents the uniqueness and nonobvious nature of their effect. The addition of succinyl glycan can effectively delay the damage of high temperature to ordered structure of liq