CN-121987537-A - Composition for synergistically inhibiting skin saccharification, application and cosmetic

Abstract

The invention belongs to the field of new daily chemical materials, and discloses a composition for synergistically inhibiting skin saccharification, which comprises, by weight, 4-6 parts of pagodatree flower ferment, 2-4 parts of albizia julibrissin bark extract and 1-3 parts of acetylhydroxyproline. The composition takes the pagodatree flower ferment, the albizia bark extract and the acetylhydroxyproline as active ingredients, has good anti-saccharification effect and has specific application potential in the aspects of whitening and anti-aging. Meanwhile, the invention also provides application and cosmetics of the composition.

Inventors

• XU ZHIWEN
• WANG PU
• MA XIUYAN

Assignees

• 上海友仁生物科技有限公司

Dates

Publication Date

20260508

Application Date

20251231

Claims (4)

1. 1. A composition for synergistically inhibiting skin glycation, which is characterized by comprising the following components in parts by weight: 4-6 parts of pagodatree flower fermented product; 2-4 parts of albizia julibrissin bark extract; 1-3 parts of acetylhydroxyproline.
2. 2. The synergistic skin glycation inhibiting composition of claim 1, wherein the composition is comprised of the following components in parts by weight: 5 parts of pagodatree flower ferment; 3 parts of albizia julibrissin bark extract; 2 parts of acetylhydroxyproline.
3. 3. Use of a composition for synergistically inhibiting skin glycation according to claim 1 or 2 for the preparation of a hair cosmetic.
4. 4. A cosmetic comprising 1 to 5wt% of the composition for synergistically inhibiting skin glycation according to claim 1 or 2.

Description

Composition for synergistically inhibiting skin saccharification, application and cosmetic Technical Field The invention relates to the field of new daily chemical materials, in particular to a composition, application and cosmetics for synergistically inhibiting skin saccharification. Background ‌ Synergistically inhibit skin glycation ‌ is used for delaying skin aging, dullness and elasticity decrease by reducing harmful Substances (AGEs) ‌ generated by binding of ‌ sugar and protein in vivo. Saccharification reactions destroy collagen and elastic fibers, leading to skin sagging, yellowing and increased wrinkles. The anti-glycation function of pagodatree flower is mentioned by the following documents: The publication number is CN106420539A, the subject is a patent application of a composition containing black tea fermentation products and application thereof, which suggests that the bud extract of pagodatree flower, namely the pagodatree flower bud extract, can beautify and nourish the face and delay aging, but the document does not explicitly suggest that the composition has anti-saccharification function. There are many reports on the anti-glycation function of cortex Albiziae, such as publication number CN118975941A, the subject is a moisturizing cosmetic composition and application thereof, and the anti-glycation ingredients include one or more of water, nicotinamide, glycerin, caprylic glycol, mixture of xanthan gum and radix salviae miltiorrhizae extract, acetyl tetrapeptide-5, carnosine, nicotinamide, resveratrol, tea polyphenol, vitamin C, tocopherol, and cortex Albiziae extract are well described in the specification. However, the use of Albizia julibrissin bark extract and Sophora japonica flower extract for anti-glycation is not mentioned in the literature. The inventors found that the raw materials have an anti-glycation effect when they are subjected to material analysis, and further proposed the present application. Disclosure of Invention The invention aims to provide a synergistic composition for inhibiting skin saccharification, which takes pagodatree flower fermented product, albizia bark extract and acetylhydroxyproline as active ingredients, has a particularly good anti-saccharification effect, and has a particularly application potential in the aspects of whitening and anti-aging. Meanwhile, the invention also provides application and cosmetics of the composition. In order to achieve the above purpose, the present invention provides the following technical solutions: A synergistic skin glycation inhibition composition comprises the following components in parts by weight: 4-6 parts of pagodatree flower fermented product; 2-4 parts of albizia julibrissin bark extract; 1-3 parts of acetylhydroxyproline. The composition is obtained by combining the three components, and the anti-saccharification mechanism is as follows: the fermentation product of flos Sophorae Immaturus has good effect in inhibiting dicarbonyl compound, and further affecting formation of glycosylation end product Interception and repair end Albizia julibrissin bark extract can simultaneously protect and repair damage of protein structure caused by saccharification by promoting specific detoxification system (glyoxalase and protease). Reconstruction end acetylhydroxyproline is followed by on one hand relieving skin inflammatory reaction by promoting ceramide synthesis and regulating skin barrier function, and on the other hand providing "building materials" required for repair for damaged collagen network, accelerating skin recovery tightening and elasticity. The skin repair is realized through the triple functions of the prevention end, the interception and repair end and the reconstruction end. Meanwhile, through the anti-saccharification test, after the three components are diluted to a certain concentration, compared with a negative control group, the cell CML content of the three components is reduced to about 80%, which indicates that the three components are combined and used, and the anti-saccharification effect is stronger. In the composition for synergistically inhibiting skin saccharification, the composition comprises the following components in parts by weight: 5 parts of pagodatree flower ferment; 3 parts of albizia julibrissin bark extract; 2 parts of acetylhydroxyproline. Meanwhile, the invention also discloses application of the composition for synergistically inhibiting skin saccharification to preparation of hair cosmetics. Finally, the invention also discloses a cosmetic, which contains 1-5wt% of the composition for synergistically inhibiting skin saccharification. Compared with the prior art, the invention has the beneficial effects that: The invention takes the pagodatree flower ferment, the albizia bark extract and the acetylhydroxyproline as active ingredients, has particularly good anti-saccharification effect and has particularly application potential in the aspects of whitening and anti-aging.