CN-121987682-A - Traditional Chinese medicine composition for treating gout and preparation method and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating gout and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition for treating gout comprises, by weight, 1-20 parts of eucommia ulmoides, 1-20 parts of achyranthes bidentata, 1-20 parts of radix angelicae pubescentis, 1-20 parts of rhizoma corydalis and 1-20 parts of notopterygium root. The traditional Chinese medicine composition takes eucommia ulmoides and achyranthes bidentata as monarch drugs, radix angelicae pubescentis and rhizoma corydalis as ministerial drugs, and notopterygium root as adjuvant drugs, and the traditional Chinese medicine composition has the effects of tonifying liver and kidney, strengthening tendons and bones, dispelling wind and removing dampness, promoting blood circulation and relieving pain, achieves the effects of reducing uric acid, eliminating swelling and relieving pain, has good treatment effect on gout, can prevent gout recurrence, and is safe and free of side effects.

Inventors

• YIN CHANGTING
• Luo Foquan
• TU WEIFENG
• CHEN YIN
• CHEN TONGXIANG

Assignees

• 宁康科技(江苏)有限公司

Dates

Publication Date

20260508

Application Date

20241106

Claims (10)

1. 1. The traditional Chinese medicine composition for treating gout is characterized by comprising, by weight, 1-20 parts of eucommia ulmoides, 1-20 parts of achyranthes bidentata, 1-20 parts of radix angelicae pubescentis, 1-20 parts of rhizoma corydalis and 1-20 parts of notopterygium root.
2. 2. The traditional Chinese medicine composition according to claim 1, wherein the composition comprises the following raw materials, by weight, 2-15 parts of eucommia ulmoides, 3-16 parts of achyranthes bidentata, 2-14 parts of radix angelicae pubescentis, 2-14 parts of rhizoma corydalis and 1.5-10 parts of notopterygium root.
3. 3. The preparation method of the traditional Chinese medicine composition according to any one of claims 1-2, which is characterized by comprising the steps of weighing the raw materials respectively, drying, crushing, sieving and mixing uniformly to obtain the traditional Chinese medicine composition.
4. 4. The method according to claim 3, wherein the mesh number of the screen is 80 to 150 mesh.
5. 5. The use of the traditional Chinese medicine composition according to any one of claims 1-2 in preparing a medicament for treating gout.
6. 6. The use according to claim 5, wherein the gout is primary gout.
7. 7. A medicament for treating gout, which is characterized by comprising the traditional Chinese medicine composition according to any one of claims 1-2 and pharmaceutically acceptable auxiliary materials.
8. 8. The medicine according to claim 7, wherein the content of the Chinese medicinal composition in the medicine is 0.01% -100%.
9. 9. The medicament of claim 7, wherein the pharmaceutical dosage form comprises a decoction, a pill, a powder, a paste, a granule, an oral liquid, a capsule, or a tablet.
10. 10. The medicament according to claim 7, wherein the auxiliary materials comprise one or more of stabilizers, binders, regulators, cosolvents, preservatives, surfactants, colorants or sweeteners.

Description

Traditional Chinese medicine composition for treating gout and preparation method and application thereof Technical Field The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating gout, and a preparation method and application thereof. Background Gout is acute and chronic inflammation and tissue injury caused by deposition of monosodium urate on parts such as bone joints, kidneys and subcutaneous parts, and is directly related to hyperuricemia caused by purine metabolic disorder and uric acid excretion reduction. Clinically, hyperuricemia and urate crystal deposition are shown, gouty arthritis can be formed if the deposition is carried out on joints, urinary tract calculus or kidney calculus can be formed if the deposition is carried out on kidneys, renal function is reduced in serious cases, and gouty nephropathy is finally formed. The conventional medicines for treating gout in Western medicine at present comprise non-steroidal anti-inflammatory drugs, colchicine, glucocorticoid and the like, and can effectively resist inflammation and relieve pain, and the common medicines comprise allopurinol, febuxostat, tribromone, probenecid and the like when uric acid lowering treatment is carried out. Although the medicines have certain curative effect on gout, the side effects are more, and the disease is easy to repeat after stopping taking the medicines. The traditional Chinese medicine is regarded as an important treatment means due to the characteristics of wide sources of raw materials, safety, no side effect and the like. Therefore, the traditional Chinese medicine composition which is safe and has no side effect, can reduce uric acid, effectively relieve gout symptoms and prevent gout recurrence is particularly important. Disclosure of Invention Therefore, the invention aims to provide the traditional Chinese medicine composition for treating gout, which can effectively reduce uric acid, eliminate swelling and relieve pain, has good treatment effect on gout, can prevent gout recurrence, and is safe and free of side effects. The invention also aims at providing a preparation method of the traditional Chinese medicine composition. The invention also aims at providing an application of the traditional Chinese medicine composition in preparing a medicine for treating gout. Another object of the present invention is to provide a medicament for treating gout. In order to achieve the above object, the present invention provides the following technical solutions: The invention provides a traditional Chinese medicine composition for treating gout, which comprises the following raw materials, by weight, 1-20 parts of eucommia ulmoides, 1-20 parts of achyranthes root, 1-20 parts of radix angelicae pubescentis, 1-20 parts of rhizoma corydalis and 1-20 parts of notopterygium root. Preferably, the composition comprises the following raw materials, by weight, 2-15 parts of eucommia ulmoides, 3-16 parts of achyranthes bidentata, 2-14 parts of radix angelicae pubescentis, 2-14 parts of rhizoma corydalis and 1.5-10 parts of notopterygium root. The invention also provides a preparation method of the traditional Chinese medicine composition, which comprises the following steps of respectively weighing the raw materials, drying, crushing, sieving and uniformly mixing. Preferably, the mesh number of the sieving is 80-150 mesh. The invention also provides application of the traditional Chinese medicine composition in preparing a medicine for treating gout. Preferably, the gout is primary gout. The invention also provides a medicine for treating gout, which comprises the traditional Chinese medicine composition and pharmaceutically acceptable auxiliary materials. Preferably, in the medicine, the content of the traditional Chinese medicine composition is 0.01% -100%. Preferably, the pharmaceutical dosage form comprises decoction, pill, powder, paste, granule, oral liquid, capsule or tablet. Preferably, the auxiliary materials comprise one or more of a stabilizer, a binder, a regulator, a cosolvent, a preservative, a surfactant, a colorant or a sweetener. The invention has the beneficial effects that: The invention provides a traditional Chinese medicine composition for treating gout, a preparation method and application thereof, the traditional Chinese medicine composition takes eucommia ulmoides and achyranthes bidentata as principal drugs, radix angelicae pubescentis and rhizoma corydalis as ministerial drugs, and notopterygium root as adjuvant drugs. The eucommia ulmoides and the achyranthes have the effects of tonifying liver and kidney and strengthening tendons and bones, and can be used together to tonify liver and kidney, strengthen tendons and bones, remove stasis and promote menstruation, induce blood to flow downwards, reduce uric acid generation and promote uric acid excretion, and can be used together wit