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CN-121987716-A - Ancient prescription innovation and promotion medicine feature combined long-acting fragrance composition capable of retaining fragrance, resolving depression, soothing nerves and aiding sleep and preparation method thereof

CN121987716ACN 121987716 ACN121987716 ACN 121987716ACN-121987716-A

Abstract

The invention relates to the technical field of fragrance, in particular to a long-acting fragrance composition for retaining fragrance, resolving depression, soothing nerves and aiding sleep, which is innovatively combined with the characteristics of a Jinzhi medicine, and a preparation method thereof. The traditional Chinese medicine composition is based on a basic tranquillizing traditional Chinese medicine composition, is matched with a synergistic composition, is matched with an aromatic sleep-aiding composition, has synergistic and complementary effects, effectively improves and treats anxiety-type insomnia, improves the problems of low emotion, difficulty in falling asleep, shallow sleep, easiness in waking and the like, has the effects of nourishing blood, tranquillizing, clearing heat and relieving restlessness by virtue of compatibility of fried wild jujube kernels, poria cocos, rhizoma anemarrhenae, ligusticum wallichii, liquorice and the like, has the effects of nourishing blood, tranquillizing, clearing heat and relieving restlessness, is matched with astragalus membranaceus, polygala tenuifolia, platycladi seeds, cortex albiziae and the like, strengthens the effects of the monarch drugs of tonifying qi, nourishing heart, relieving depression and tranquilizing, is matched with albizia flower and albizia bark flower leaves, relieves the emotion multiply, relieves depression and is matched with the aromatic sleep-aiding composition of roses, lavender, fingered citron, dried orange peel and the like, so that the fragrance is soft, rich in level, bitter and astringent taste and pungent feeling of the traditional Chinese medicine are optimized, and the fragrance is kept for a long time.

Inventors

  • TONG LING
  • WANG HONGDAN
  • HOU WENJING
  • CHEN YUXUAN
  • LIU WENYUE
  • WANG HUIZI

Assignees

  • 山西医科大学

Dates

Publication Date
20260508
Application Date
20260401

Claims (9)

  1. 1. The long-acting fragrance composition for keeping fragrance, resolving depression, soothing nerves and aiding sleep, which is innovatively combined with the feature of a jin medicine, is characterized by comprising a basic nerve soothing traditional Chinese medicine composition, a synergistic composition and an aromatic sleep aiding composition in a weight ratio of (1-2); the basic tranquillizing Chinese medicinal composition comprises the following raw materials in parts by weight: 10-30 parts of fried spina date seed, 5-15 parts of poria cocos, 5-15 parts of rhizoma anemarrhenae, 3-10 parts of ligusticum wallichii and 2-6 parts of liquorice; The synergistic composition comprises the following raw materials in parts by weight: 5-15 parts of astragalus membranaceus, 3-10 parts of polygala tenuifolia, 5-15 parts of platycladi seed and 3-10 parts of cortex albiziae; the aromatic sleep-aiding composition comprises the following raw materials in parts by weight: 3-10 parts of albizia flower, 3-10 parts of rose, 3-10 parts of lavender, 2-6 parts of dried orange peel, 2-6 parts of fingered citron and 1-5 parts of sandalwood.
  2. 2. The long-acting fragrance composition for retaining fragrance, resolving depression, soothing nerves and aiding sleep, which is innovatively integrated with the characteristics of a jin medicine according to claim 1, wherein the places where astragalus membranaceus, polygala tenuifolia, platycladi seed and cortex albiziae are produced are all Shanxi.
  3. 3. The use of an ancient prescription innovative and advanced drug feature-integrated long-acting fragrance-retaining, depression-relieving, nerve-soothing and sleep-aiding fragrance composition as claimed in claim 1 or 2 in the preparation of products for treating and/or assisting in treating insomnia.
  4. 4. The use according to claim 3, wherein the insomnia comprises anxiety insomnia.
  5. 5. Use according to claim 3, wherein the product comprises a sleep aid perfume, a sleep spray, a pillow fragrance spray, a fragrance, a balm or a sachet.
  6. 6. A sleep-aiding spray, which is characterized by being prepared from the long-acting fragrance-retaining, depression-relieving, nerve-soothing and sleep-aiding fragrance composition according to claim 1 or 2 and pharmaceutically acceptable auxiliary materials.
  7. 7. A sleep-aiding spray according to claim 6, characterized in that the preparation comprises the steps of: ① Preparing essential oil from the raw materials of the basic tranquilization traditional Chinese medicine composition and the aromatic sleep-aiding composition by steam distillation or supercritical extraction; Extracting the synergistic composition with an extraction solvent to obtain an extract; ② Adding the essential oils prepared in the step ① into a solvent, adding vanillyl butyl ether, and stirring to dissolve each other; ③ Adding the extract into the solution obtained in the step ② after mutual dissolution, and stirring until no delamination exists; ④ Slowly pouring deionized water, stirring while adding, sealing the container after stirring uniformly, and standing at shade place for 24-72 hr.
  8. 8. A sleep-aid spray according to claim 7, wherein the solvent in step ② is a mixed solvent prepared by adding β -cyclodextrin to an ethanol solution.
  9. 9. A sleep-aid spray according to claim 7, wherein the extraction solvent in step ① is selected from water, alcohol or an aqueous alcohol solution.

Description

Ancient prescription innovation and promotion medicine feature combined long-acting fragrance composition capable of retaining fragrance, resolving depression, soothing nerves and aiding sleep and preparation method thereof Technical Field The invention relates to the technical field of fragrance, in particular to a long-acting fragrance composition for retaining fragrance, resolving depression, soothing nerves and aiding sleep, which is innovatively combined with the characteristics of a Jinzhi medicine, and a preparation method thereof. Background Insomnia has become a high sub-health problem in modern society, and most people have difficulty in falling asleep, shallow sleep, easy awakening and early awakening caused by liver depression, qi stagnation, heart blood deficiency, internal disturbance of deficiency heat and anxiety. Traditional methods of treating insomnia mainly include drug therapy and behavioral therapy. However, long-term use of hypnotics may produce dependency and a series of side effects such as the existence of dependency, a feeling of hangover in the morning, daytime sleepiness, inattention, memory decline, etc. Therefore, people gradually turn to a safer and natural therapy to improve sleep quality, such as fragrance products like sleep-aiding aromatherapy or perfume, but most of the fragrance products like sleep-aiding aromatherapy and perfume sold in the market at present are chemically synthesized and calm components, single essential oil or floral fragrance are blended, so that the problems of unstable efficacy, short sleep-aiding effect and the like exist, and the defects of undefined components, single fragrance level, insufficient long-term use safety and the like exist. The traditional Chinese medicine is mainly in an oral dosage form, is inconvenient to take, and is difficult to integrate into daily chemical scenes. The fragrance product is convenient to use, but the traditional Chinese medicine is rarely prepared into a fragrance dosage form, and even if the fragrance dosage form is used, the fragrance dosage form has the problems of short fragrance retention time, heavy bitter and harsh taste of the traditional Chinese medicine, separation of depression relieving and sleep aiding effects and the like. Therefore, it is necessary to develop a fragrance product which is prepared from traditional Chinese medicines, has high-grade soft fragrance, no bitter taste of the medicines, and has remarkable depression relieving and sleep aiding effects for a long time. Disclosure of Invention Therefore, aiming at the defects of the prior art, the invention provides a long-acting fragrance composition for retaining fragrance, resolving depression, soothing nerves and aiding sleep and a preparation method thereof, which is based on a basic traditional Chinese medicine composition for soothing nerves, the synergistic composition and the aromatic sleep-aiding composition are used for cooperation to prepare the traditional Chinese medicine with rich fragrance, no bitter and harsh taste of the traditional Chinese medicine, and the effects of soothing liver, relieving depression, nourishing heart, soothing nerves and the like can be realized, so that the problems of weak effect, short fragrance and poor safety of the traditional sleep-aiding fragrance are solved. The technical scheme provided by the invention is as follows: The long-acting fragrance composition for keeping fragrance, resolving depression, soothing nerves and aiding sleep, which is innovatively combined with the feature of a jin medicine, is composed of a basic nerve-soothing traditional Chinese medicine composition, a synergistic composition and an aromatic sleep-aiding composition in a weight ratio of (1-2); the basic tranquillizing Chinese medicinal composition comprises the following raw materials in parts by weight: 10-30 parts of fried spina date seed, 5-15 parts of poria cocos, 5-15 parts of rhizoma anemarrhenae, 3-10 parts of ligusticum wallichii and 2-6 parts of liquorice; The synergistic composition comprises the following raw materials in parts by weight: 5-15 parts of astragalus membranaceus, 3-10 parts of polygala tenuifolia, 5-15 parts of platycladi seed and 3-10 parts of cortex albiziae; the aromatic sleep-aiding composition comprises the following raw materials in parts by weight: 3-10 parts of albizia flower, 3-10 parts of rose, 3-10 parts of lavender, 2-6 parts of dried orange peel, 2-6 parts of fingered citron and 1-5 parts of sandalwood. Preferably, the places of production of the astragalus, the polygala tenuifolia, the platycladi seed and the cortex albiziae are Shanxi. Based on the same inventive concept, the invention also provides application of the long-acting fragrance composition with the ancient prescription innovation and promotion of the characteristics of the Jinzhi medicine in preparing products for treating and/or assisting in treating insomnia. Preferably, the insomnia comprises anxiety insomni