CN-121987722-A - Traditional Chinese and Tibetan medicine composition for improving oestrus rate of yaks

Abstract

The invention belongs to the field of animal breeding, and particularly relates to a traditional Chinese and Tibetan medicine composition for improving oestrus rate of yaks. Solves the technical problems of low oestrus rate, difficult regulation and control and great side effect caused by using hormone. The specific technical scheme includes that the pharmaceutical composition comprises ginseng, epimedium, angelica, motherwort, hucho taimen, medlar, prepared rehmannia root, ligusticum wallichii, bighead atractylodes rhizome, mango seed, myrobalan and acorus calamus. The prescription provided by the invention regulates the reproductive system of the yaks in multiple aspects through reasonable compatibility of monarch, minister, assistant and guide, enhances the kidney function, improves the blood circulation of reproductive organs, promotes nutrient absorption and enhances the overall health state, thereby achieving the purpose of promoting the oestrus and the hybridization of the yaks.

Inventors

• WANG LI
• WEI YONG
• MA BO
• Suo Langda
• BAN DAN
• Gesang Draga
• Tsdanzhuoga
• PING CUO

Assignees

• 西南民族大学

Dates

Publication Date

20260508

Application Date

20260210

Claims (4)

1. 1. A pharmaceutical composition is characterized by comprising ginseng, epimedium, angelica, motherwort, hucho taimen, medlar, prepared rehmannia root, szechuan lovage rhizome, bighead atractylodes rhizome, mango seed, myrobalan and sweelflag rhizome.
2. 2. The pharmaceutical composition of claim 1, wherein the pharmaceutical composition comprises, by mass, 10-15 parts of ginseng, 20-30 parts of epimedium, 15-25 parts of angelica sinensis, 15-25 parts of motherwort, 6-12 parts of hucho taimen, 10-15 parts of wolfberry fruit, 10-15 parts of prepared rehmannia root, 8-12 parts of ligusticum wallichii, 8-12 parts of bighead atractylodes rhizome, 6-12 parts of mangiferin fruit core, 10-15 parts of lithocarpus fruit and 8-12 parts of rhizoma acori graminei.
3. 3. A pharmaceutical preparation comprising the pharmaceutical composition according to claim 1 or 2.
4. 4. The pharmaceutical preparation according to claim 3, wherein the pharmaceutical preparation is any one of decoction, powder, pill, paste, medicated wine, pellet, tablet, capsule, granule, injection or aerosol.

Description

Traditional Chinese and Tibetan medicine composition for improving oestrus rate of yaks Technical Field The invention belongs to the field of animal breeding, and particularly relates to a traditional Chinese and Tibetan medicine composition for improving oestrus rate of yaks. Background The natural breeding period of the yaks is one embryo of two years, and the period of the postpartum anemic period is as long as 3-4 months. And part of cows have corpus luteum cyst or insufficient functions, which results in hormone regulation failure. Moreover, the yak oestrus time is short (12-18 h), external symptoms are not obvious, and the breeding time is easy to miss. Therefore, the oestrus of the yaks is difficult to regulate and control, and becomes one of important factors for limiting the breeding of the yaks. At present, the oestrus regulation of yak cows is mainly hormone regulation, and although the methods are various, obvious limitations exist, and mainly comprise (1) a progestin implantation method, namely, regulating oestrus cycle by implantation of a progestin-containing silica gel plug (such as CIDR) or a plastic tube and injection of progestin serum gonadotropin (PMSG). The oestrus rate of the method can reach more than 90%, the pregnancy rate is 70% -80%, but surgical operation is needed, and infection can be caused. (2) Prostaglandin injection method comprises intramuscular injection of chlorprostaenol (PG) to dissolve corpus luteum and induce estrus. The oestrus rate of the secondary injection can reach 100%, but the luteal phase needs to be accurately judged, and the secondary injection is ineffective for cows without functional luteal phase. (3) Gonadotrophin releasing hormone (GnRH), which is used in combination with PG (e.g., gnrh+pg+gnrh regimen), induces estrus by modulating the hypothalamic-pituitary-gonadal axis. The scheme has the best effect on the postpartum anemic cows, and the oestrus rate is obviously improved. However, these methods have the problems of complex operation, high cost and large side effects (long-term use may cause ovarian cyst, high early embryo mortality rate and the like), and are difficult to popularize and apply on a large scale in production. In contrast, the traditional Chinese medicine composition is natural and safe, multi-target-point-adjustable, low in cost, easy in raw material acquisition, simple in preparation process and suitable for large-scale popularization. Although the traditional Chinese medicine composition has obvious advantages in the aspect of yak oestrus regulation, in the current public report, the application research of the traditional Chinese medicine composition in the aspect of yak oestrus regulation is less, and no clinical test proves the effectiveness of the traditional Chinese medicine composition in yaks. Therefore, the traditional Chinese medicine composition capable of effectively regulating and controlling the oestrus of yaks has important application value. Disclosure of Invention The invention aims to provide a traditional Chinese and Tibetan medicine composition for improving oestrus rate of yaks. The technical scheme adopted by the invention is that the medicine composition comprises ginseng, epimedium herb, chinese angelica, motherwort herb, hucho taimen, medlar, prepared rehmannia root, szechuan lovage rhizome, largehead atractylodes rhizome, mango seed, myrobalan and Tibetan calamus. Preferably, the pharmaceutical composition comprises, by mass, 10-15 parts of ginseng, 20-30 parts of epimedium, 15-25 parts of angelica sinensis, 15-25 parts of motherwort, 6-12 parts of hucho taimen, 10-15 parts of medlar, 10-15 parts of prepared rehmannia root, 8-12 parts of ligusticum wallichii, 8-12 parts of bighead atractylodes rhizome, 6-12 parts of mangiferous fruit seeds, 10-15 parts of lithocarpus fruit and 8-12 parts of sweelflag rhizome. Accordingly, a pharmaceutical formulation comprising the pharmaceutical composition. The medicinal preparation is any one of decoction, powder, pill, paste, medicated wine, pill, tablet, capsule, granule, injection or aerosol. The pharmaceutical composition or the pharmaceutical preparation can improve the oestrus rate of the yaks, improve the constitution of the yaks, increase the concentration of the yak reproductive hormones (LH, FSH and E2), improve the microbial community structure of the genital tract of the yaks (promote the proliferation of beneficial flora represented by the phylum Thick-walled bacteria), and strengthen the regulation of the HPGA axis of gonadotropin releasing hormone (GnRH), gonadotropin and estrogen. The invention has the beneficial effects that the invention discloses a traditional Chinese and Tibetan medicine composition capable of improving oestrus rate of yak cows, which consists of pure herbaceous plants, can greatly stimulate oestrus of cows, reduce hormone residues and meet the requirements of green products. The effects and the meaning analysis of each drug compone