CN-121987733-A - Noon tea tablet and preparation method thereof

Abstract

The invention provides a noon tea tablet and a preparation method thereof. The invention successfully prepares the noon tea tablet by using a wet granulation process, solves the problem of inconvenient use of the original noon tea preparation (granules and hard capsules), and meets the market demands more. The preparation method of the tablet composition has simple process, reduces the cost of the pharmaceutical preparation, saves economy and is suitable for large-scale industrial production.

Inventors

• LIU YUHAN
• Song Meitong
• YIN YONGMEI

Assignees

• 南开大学

Dates

Publication Date

20260508

Application Date

20241101

Claims (5)

1. 1. A noon tea tablet is characterized in that the tablet is prepared from noon tea extract, microcrystalline cellulose, sodium carboxymethyl starch and magnesium stearate.
2. 2. The noon tea tablet of claim 1, characterized in that it comprises the following ingredients in weight percent: Adding 35-38% of noon tea extract (after drying), 53-60% of microcrystalline cellulose; the additive comprises 5 to 7 percent of sodium carboxymethyl starch and 0.8 to 1.2 percent of magnesium stearate.
3. 3. The noon tea tablet of claim 1, wherein the noon tea extract is prepared from rhizoma Atractylodis, radix bupleuri, rhizoma Et radix Notopterygii, radix Saposhnikoviae, radix Angelicae Dahuricae, rhizoma Chuanxiong, herba Pogostemonis, radix Peucedani, fructus forsythiae, pericarpium Citri Reticulatae, fructus crataegi, fructus Aurantii Immaturus, fructus Hordei Germinatus (parched), radix Glycyrrhizae, massa Medicata Fermentata (parched), radix Platycodonis, folium Perillae, and cortex Magnoliae officinalis.
4. 4. The noon tea tablet of claim 1, characterized in that the noon tea extract is prepared by soaking each herb in distilled water which has been used for the herb for 64min at normal temperature, decocting for 2 times at about 60 ℃ each time for 1 hour, filtering with gauze, mixing the filtrates, evaporating to thick paste, and cooling at room temperature.
5. 5. The noon tea tablet according to claim 1, characterized in that the tablet is prepared by adding microcrystalline cellulose to the extract to prepare a suitable soft material, adding a small amount of absolute ethyl alcohol, granulating with a 10 mesh sieve, drying, and granulating with a 16 mesh sieve and a 80 mesh sieve to obtain granules. Adding magnesium stearate and sodium carboxymethyl starch, and tabletting.

Description

Noon tea tablet and preparation method thereof Technical Field The invention relates to the technical field of pharmaceutical preparations, in particular to a noon tea tablet and a preparation method thereof. Background The noon tea prescription is derived from Tianzhong tea in Qing dynasty "Shuxiaojie Liang Fang", is prepared by adding, modifying and cutting the Tianzhong tea, and is a teabag preparation, and the prescription comprises rhizoma atractylodis, radix bupleuri, notopterygium root, radix sileris, radix angelicae, rhizoma ligustici wallichii, pogostemon cablin, radix peucedani, fructus forsythiae, dried orange peel, hawthorn, immature bitter orange, malt (stir-fried), liquorice, medicated leaven (stir-fried), platycodon grandiflorum, perilla leaf, magnolia officinalis and black tea. The prescription has sweet and bitter taste, has tea fragrance, has the functions of dispelling wind and cold, dispelling exterior and relieving stagnation, and resolving turbidity and harmonizing stomach, and is mainly used for treating exogenous wind-cold, headache and cough, general ache, aversion to cold or accompanied with mild fever, internal injury diet, damp stagnation and food retention, abdominal distention and fullness, anorexia or accompanied with aversion to cold, vomiting and diarrhea, lassitude and hypodynamia, seasickness and seasickness, and water-soil inataking. Modern clinical noon tea is often used for treating symptoms of food retention, vomiting and diarrhea, chill and fever caused by exogenous wind-cold and spleen-stomach dysfunction or improper diet caused by water and soil deficiency. Many families are used to apply the noon tea in cold and diarrhea, but the noon tea particles and hard capsules in the market cannot completely meet the market demands of the modern society, and the granule has higher cost, deliquescence, poor palatability, inconvenient use, slower onset of action and higher cost. Therefore, we hope to explore the preparation of the noon tea tablets to solve the problems of inconvenient use and high cost of noon tea. Disclosure of Invention In view of the above, the present invention provides a noon tea tablet and a preparation method thereof, which solve the above problems. The technology of the invention is realized in that the noon tea tablet is prepared from the following raw materials of noon tea extract, microcrystalline cellulose, sodium carboxymethyl starch and magnesium stearate. The further proposal is that the tablet is prepared by the raw materials with the weight percentage of 35 to 38 percent of noon tea extract (after drying), 53 to 60 percent of microcrystalline cellulose, 5 to 7 percent of carboxymethyl starch sodium and 0.8 to 1.2 percent of magnesium stearate. The further scheme is that the tablet comprises the following components of 5g of noon tea extract (weight after drying), 7.5g of microcrystalline cellulose, 0.8g of carboxymethyl starch sodium and 0.13g of magnesium stearate. The further proposal is that the noon tea extract is prepared from the following medicinal materials of rhizoma atractylodis, radix bupleuri, notopterygium root, radix sileris, radix angelicae, rhizoma ligustici wallichii, patchouli, radix peucedani, fructus forsythiae, dried orange peel, hawthorn, fructus aurantii immaturus, malt (stir-fried), liquorice, medicated leaven (stir-fried), platycodon grandiflorum, perilla leaf and magnolia officinalis. The further scheme is that the noon tea extract is prepared by soaking the medicinal materials in distilled water without medicinal materials at normal temperature for 64min, decocting for 2 times, each time for 1 hour, filtering with gauze, mixing filtrates, evaporating to thick paste, and cooling at room temperature. The preparation method of the noon tea tablet comprises the following steps: Adding microcrystalline cellulose into the extract to prepare a proper soft material, Adding a small amount of absolute ethyl alcohol, quickly granulating by a 10-mesh sieve, Drying, sieving with 16 mesh sieve and 80 mesh sieve, granulating to obtain granule, Adding magnesium stearate and sodium carboxymethyl starch, and tabletting. The noon tea tablet prepared by the invention has good disintegration and simple process, and is beneficial to solving the problem of inconvenient use of other formulations of noon tea. Drawings FIG. 1 preparation of a soft mass from raw materials. FIG. 2A is a graph prepared from a soft material and tested. Detailed Description In order to better understand the technical content of the present invention, the following provides specific examples to further explain the present invention. The experimental methods used in the embodiment of the invention are conventional methods unless otherwise specified. Materials, reagents, and the like used in the examples of the present invention are commercially available unless otherwise specified. The noon tea tablet prescription comprises 5g of noon tea extract (weight after drying