CN-121987874-A - Dialysate supply system of hemodialysis machine

CN121987874ACN 121987874 ACN121987874 ACN 121987874ACN-121987874-A

Abstract

The invention relates to the technical field of hemodialysis machines, in particular to a dialysate supply system of a hemodialysis machine, which comprises a concentrated solution supply module, a dialysate mixing module, a concentration detection module, a data storage module, an intelligent control module and a centralized control module, wherein the concentrated solution supply module dynamically analyzes real-time states of patients through deep learning, automatically adjusts dialysate components, realizes spanning from fixed formulas to individual dynamic supply, remarkably improves treatment effects, can foreseeably forecast risks such as hypotension, hyperkalemia and the like, actively intervenes in advance, reduces incidence rate of acute complications related to dialysis, and automatically and intelligently controls the automatic intelligent control, so that the workload of frequent manual parameter adjustment of medical staff is greatly reduced, the clinical decision is more focused, and medical resource allocation is optimized.

Inventors

CHEN YI
Zhang Yaner
LUO HUIQIN

Assignees

舟山医院

Dates

Publication Date: 20260508
Application Date: 20260116

Claims (10)

1. A dialysate supply system for a hemodialysis machine is characterized by comprising: the concentrated solution supply module is used for storing and conveying a plurality of dialysis concentrated solutions and monitoring the residual quantity of the concentrated solutions in real time; The dialysate mixing module is connected with the concentrated solution supply module and the reverse osmosis water supply system and is used for mixing the concentrated solution and the reverse osmosis water according to an accurate proportion to prepare dialysate meeting the treatment requirement; The concentration detection module is connected with the dialysate mixing module and is used for continuously detecting the concentration of potassium ions, sodium ions, calcium ions, magnesium ions and bicarbonate ions in the dialysate in real time; The data storage module is used for storing the whole running flow record of the system, the detection result of the concentration detection module, the analysis result of the intelligent control module and the training data of the intelligent control module; The intelligent control module is respectively in communication connection with the concentration detection module, the dialysate mixing module, the patient physiological signal monitoring equipment and the medical information system and is used for carrying out comprehensive analysis and risk assessment according to the multisource data acquired in real time to generate personalized dialysate parameter adjustment instructions; And the centralized control module is used for checking the identity information of the patient and the identity information of medical staff, performing centralized control management on the concentrated solution supply module, the dialysate mixing module, the concentration detection module, the data storage module and the intelligent control module, and recording the operation flow of the system.
2. The dialysate supply system of a hemodialysis machine of claim 1, wherein the concentrate supply module includes: A liquid storage container for storing the acidic concentrated liquid; A liquid B storage container for storing the alkaline concentrated liquid; the weight sensor is used for detecting the weight of the liquid storage container A and the weight of the liquid storage container B in real time, and sending an alarm prompt to the centralized control module when the weight of the liquid storage container A or the weight of the liquid storage container B exceeds the change of a threshold value; A conveying pump for conveying the acidic concentrated solution and the alkaline concentrated solution; And the flow sensor is used for detecting the liquid discharge amount of the conveying pump and sending a prompt to the centralized control module when the liquid discharge amount of the conveying pump changes beyond a threshold value.
3. The dialysate supply system of a hemodialysis machine of claim 1, wherein the dialysate mixing module comprises: A mixing container for storing the acidic concentrated solution, the alkaline concentrated solution and the reverse osmosis water; a stirrer for stirring the liquid in the mixing container to form a dialysis liquid; a heater for heating the liquid in the mixing container; And the temperature sensor monitors the temperature of the dialysate, ensures that the temperature of the dialysate is in a required range, and sends a prompt to the centralized control module when the temperature of the dialysate changes beyond a threshold value.
4. The dialysis fluid supply system of a hemodialysis machine of claim 1, wherein the concentration detection module employs an integrated ion-selective electrode array capable of simultaneously detecting a plurality of ion concentrations of potassium, sodium, calcium, magnesium, chlorine and bicarbonate, and each electrode channel specifically detects a specific ion, and is equipped with an automatic calibration and temperature compensation function to ensure a measurement accuracy within + -2%.
5. The dialysate supply system of a hemodialysis machine of claim 1, wherein the intelligent control module comprises: The data fusion unit is respectively in communication connection with the concentration detection module, the dialysate mixing module, the patient physiological signal monitoring equipment and the medical information system, acquires diagnosis and treatment data of the patient and data during dialysis of the patient, adopts a dynamic time warping algorithm to solve the problem that data acquisition frequencies of different equipment are inconsistent, establishes a uniform time reference, and simultaneously recognizes and eliminates abnormal data in the data through a built-in abnormal detection algorithm to ensure the reliability of the input data; The multi-mode deep learning analysis unit is used for simultaneously processing the time sequence signals and the static data through the mixed deep learning model and predicting risks in a plurality of hours in the future; The intelligent decision unit is used for receiving the analysis result of the multi-mode deep learning analysis unit and the clinical guideline and the expert knowledge base embedded in the analysis result, making a proportioning scheme of the patient dialysate or carrying out fine adjustment on the dialysis scheme of the patient in the dialysis process of the patient; And the control signal output unit is used for converting the scheme into a specific and executable control instruction after the scheme of the medical staff is confirmed and transmitting the specific and executable control instruction to the concentrated solution supply module, the dialysate mixing module and the concentration detection module.
6. The dialysis fluid supply system of a hemodialysis machine of claim 5, wherein the multi-modal deep learning analysis unit employs a hybrid model architecture including a graph neural network and a time series convolution network for mining complex nonlinear relationships between physiological data and dialysis fluid parameters and performing multi-task learning while predicting risk of hypotension, hyperkalemia and insufficient dialysis.
7. The dialysate supply system of a hemodialysis machine of claim 1, wherein the data storage module comprises: the data classifying unit classifies the received data; The data management unit is used for setting the storage period of the data and deleting the data exceeding the storage period so as to ensure that the data storage unit has enough space for use; And the data storage unit is used for storing the classified data.
8. The dialysis fluid supply system of a hemodialysis machine of claim 1, wherein said centralized control unit comprises: An identity checking unit for checking the identity information of the patient and the identity information of the medical staff; the control management unit is used for carrying out centralized control management on the concentrated solution supply module, the dialysate mixing module, the concentration detection module, the data storage module and the intelligent control module; and the flow recording unit is used for recording the running flow of the system.
9. The dialysis fluid supply system of a hemodialysis machine of claim 8, wherein the centralized control unit is further provided with: and the remote monitoring unit is convenient for medical staff to remotely monitor the operation of the system and receive the high-level information sent by the system.
10. The dialysate supply system of a hemodialysis machine of claim 9, wherein the control method includes the steps of: S1, identifying the identity of a patient through a centralized control module, automatically retrieving historical data, evaluating the state of the patient through an intelligent control module, generating an initial dialysate prescription, monitoring the residual quantity of concentrated solution in real time, and guaranteeing the safety of the patient; S2, according to the generated dialysis prescription, the concentrated solution supply module and the dialysis solution mixing module are used for preparing the dialysis solution, and are connected with the dialysis solution mixing module through the concentration detection module, so that the concentrations of potassium ions, sodium ions, calcium ions, magnesium ions and bicarbonate ions in the dialysis solution are continuously detected in real time, the safety of a patient is ensured, and then the patient carries out dialysis according to the prepared dialysis solution; S3, continuously collecting multi-source data in the dialysis process of the patient, performing real-time risk assessment through an intelligent control module, and dynamically adjusting parameters of the dialysate; s4, after the dialysis is finished, a treatment report is generated, deep learning model parameters are optimized based on treatment effect feedback, and the dialysis condition of the patient is archived; s5, the data storage module stores the whole running flow record of the system, the detection result of the concentration detection module, the analysis result of the intelligent control module and the training data of the intelligent control module, so that when the system has problems, the problems can be traced.

Description

Dialysate supply system of hemodialysis machine Technical Field The invention relates to the technical field of hemodialysis machines, in particular to a dialysate supply system of a hemodialysis machine. Background The dialysate supply system of the hemodialysis machine is a core component of hemodialysis treatment and is responsible for preparing, conveying and monitoring the dialysate meeting the treatment requirements, ensuring accurate and controllable parameters such as components, temperature, flow rate and the like, and the proportion and supply of the dialysate can be realized by the conventional dialysate supply system such as the dialysate supply system disclosed in the patent with the publication number of CN107427620B, the method and equipment for supplying the dialysate to the dialysis equipment disclosed in the patent with the publication number of CN107073189B and the like. However, during use, it has been found that existing dialysate supply systems are mainly based on a fixed formulation or a limited and adjustable design concept, and such systems typically include a concentrate storage device, a proportional mixing system, a heating device and a concentration monitoring system, and although modern hemodialysis machines have achieved a high degree of mechanical precision and automation, most use a fixed electrolyte formulation, or only allow for manual adjustment by a medical staff in a limited range according to experience, which is inconvenient to fine-tune according to individual conditions of a patient, and parameters such as blood pressure, heart rate, blood volume, electrolyte level and the like are continuously changed along with ultrafiltration, solute removal and organism compensation reaction during dialysis, existing dialysate supply systems lack real-time sensing and response capabilities for these physiological parameter changes, often only when complications have occurred or are imminent, which is difficult for medical staff to intervene in adjusting, and consequently affects the dialysis effect, resulting in poor practicality, so that improvement of existing dialysate supply systems is needed. Disclosure of Invention In order to solve the technical problems, the invention provides the dialysate supply system of the hemodialysis machine, which can dynamically analyze the real-time state of a patient through deep learning, automatically adjust the dialysate components, realize the spanning from a fixed formula to individual dynamic supply, remarkably improve the treatment effect, and can predict risks such as hypotension, hyperkalemia and the like in advance, actively intervene in advance, reduce the incidence rate of acute complications related to dialysis, greatly reduce the workload of medical staff for frequently and manually adjusting parameters through automatic intelligent control, so that the dialysate supply system can be more focused on clinical decisions and optimize the distribution of medical resources. The dialysate supply system of the hemodialysis machine of the present invention includes: the concentrated solution supply module is used for storing and conveying a plurality of dialysis concentrated solutions and monitoring the residual quantity of the concentrated solutions in real time; The dialysate mixing module is connected with the concentrated solution supply module and the reverse osmosis water supply system and is used for mixing the concentrated solution and the reverse osmosis water according to an accurate proportion to prepare dialysate meeting the treatment requirement; The concentration detection module is connected with the dialysate mixing module and is used for continuously detecting the concentration of potassium ions, sodium ions, calcium ions, magnesium ions and bicarbonate ions in the dialysate in real time; The data storage module is used for storing the whole running flow record of the system, the detection result of the concentration detection module, the analysis result of the intelligent control module and the training data of the intelligent control module; The intelligent control module is respectively in communication connection with the concentration detection module, the dialysate mixing module, the patient physiological signal monitoring equipment and the medical information system and is used for carrying out comprehensive analysis and risk assessment according to the multisource data acquired in real time to generate personalized dialysate parameter adjustment instructions; The centralized control module is used for checking the identity information of the patient and the identity information of medical staff, performing centralized control management on the concentrated solution supply module, the dialysate mixing module, the concentration detection module, the data storage module and the intelligent control module, and recording the operation flow of the system; The system can predict risks such as hypotension, hyperkalemia a