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CN-121987902-A - Inhalation drug administration device

CN121987902ACN 121987902 ACN121987902 ACN 121987902ACN-121987902-A

Abstract

The invention discloses an inhalation drug administration device, and relates to the technical field of medical auxiliary instruments. Aiming at the problems that the existing inhalation administration device cannot monitor the real-time breathing state of a patient, medicine waste is easy to cause and necessary safety is lacking, the inhalation administration device comprises a mask, an atomizer and a breathing monitoring component, wherein the atomizer is connected with the mask through an administration pipeline, the breathing monitoring component is connected with the mask through a breathing pipeline, and a control valve component is further arranged between the breathing monitoring component and the atomizer and used for blocking the connection of the atomizer and the mask when the patient exhales; the respiratory monitoring assembly is capable of adaptively adjusting according to the patient's expiratory strength to allow the expired gases to be expelled at different rates. The invention can dynamically monitor the respiration of the patient, can avoid the waste of medicines, and improves the use safety of the device by self-using exhaust.

Inventors

  • GU YAN
  • HAN RUI
  • WANG JIAXING
  • GU JUN
  • LIU JINGTAO
  • SONG YICHANG
  • ZHANG YUXIANG
  • LIU XIANGDI
  • LI RONG
  • YU JINGGANG

Assignees

  • 中国人民解放军总医院第八医学中心

Dates

Publication Date
20260508
Application Date
20260227

Claims (10)

  1. 1. Inhalation delivery device comprising a mask (1) and a nebulizer (2), the mask (1) and the nebulizer (2) being connected by a delivery conduit (4), characterized in that the device further comprises: The respiratory monitoring assembly (3) is connected with the mask (1) through a respiratory pipeline (5) and is used for dynamically monitoring the expiratory intensity of a patient in real time and discharging the gas exhaled by the patient; and the control valve assembly (6) is connected with the respiration monitoring assembly (3) and the atomizer (2) and is used for sealing the atomizer (2) from the drug administration pipeline (4) when a patient exhales gas.
  2. 2. An inhalation-administration device according to claim 1, wherein the breath monitoring assembly (3) comprises: One end of the connecting seat (301) is connected with the mask (1) through a breathing pipeline (5), and the other end of the connecting seat is movably connected with a sealing plate (304) for adjusting the exhaust gas quantity; an expiration sleeve (302) connected with the control valve assembly (6) and provided with an air outlet hole (3021); an identification sleeve (303) connected with one end of the connection seat (301) far away from the atomizer (2); And an airflow control and monitoring unit penetrating through the exhalation sleeve (302) and the identification sleeve (303).
  3. 3. An inhalation-drug delivery device according to claim 2, wherein the airflow control monitoring unit comprises: a first piston (3022) slidably mounted in the exhalation sleeve (302) for sealing and opening the outlet aperture (3021); The control rod (305) is connected with the first piston (3022), penetrates through the expiration sleeve (302) and the identification sleeve (303), and is arranged at one end outside the identification sleeve (303) and provided with an identification section of a bar body.
  4. 4. An inhalation-drug delivery device according to claim 3 wherein the airflow control monitoring unit further comprises: The limiting plate (3031) is sleeved on the control rod (305) and is positioned in the identification sleeve (303); And a first reset piece (3032) which is connected with the control rod (305) and the connecting seat (301).
  5. 5. An inhalation-administration device according to claim 2, wherein the breath monitoring assembly (3) further comprises: the two connecting lugs (3011) are symmetrically arranged on the connecting seat (301); the two pressure regulating rods (3012) respectively penetrate through the two connecting lugs (3011) correspondingly and are connected with the sealing plate (304); And a fourth reset piece (3013) connected with the connecting lug (3011) and contacted with one end of the pressure regulating rod (3012) positioned outside the connecting lug (3011).
  6. 6. An inhalation delivery device according to claim 5 characterised in that the centre of the closure plate (304) is provided with a pressure relief mesh (3041).
  7. 7. An inhalation-device according to claim 2, characterised in that the atomiser (2) is provided with an air inlet (201), a compressed gas inlet (202), a liquid drug inlet (203) and a drug outlet (204).
  8. 8. The inhalation delivery device of claim 7, wherein said control valve assembly comprises: A transmission tube (601) having one end connected to the exhalation sleeve (302); A first drive leg (602) in communication with an end of the drive tube (601) remote from the exhalation sleeve (302) and in communication with the air inlet port (201) through an air inlet valve assembly (604); the second transmission branch pipe (603) is communicated with the middle part of the first transmission branch pipe (602) and is communicated with the medicine outlet (204) through a breather valve assembly (605).
  9. 9. The inhalation delivery device according to claim 8, wherein the air inlet valve assembly (604) comprises: an air inlet valve body (6041), two ends of which are respectively communicated with the first transmission branch pipe (602) and the air inlet port (201); A second piston member (6042) slidably sealed within the air inlet valve body (6041); And the two ends of the second reset piece (6043) are respectively connected with the plug body of the second piston piece (6042) and the air inlet valve body (6041).
  10. 10. The inhalation delivery device according to claim 8, wherein the air inlet valve assembly (604) comprises: The two ends of the breather valve component (605) are respectively communicated with the second transmission branch pipe (603) and the medicine outlet (204); A third piston member (6052) slidably disposed within the breather valve assembly (605); And two ends of the third reset piece (6053) are respectively connected with the plug body of the third piston piece (6052) and the breather valve assembly (605).

Description

Inhalation drug administration device Technical Field The invention relates to the technical field of medical auxiliary instruments, in particular to an inhalation administration device. Background In clinical treatment of respiratory and critical medical departments, the inhaled administration has the advantages of quick effect, small systemic side effect, accurate dosage and the like because the medicament can directly act on respiratory tract and lung target organs, and has become one of core treatment means of diseases such as asthma, chronic Obstructive Pulmonary Disease (COPD), respiratory failure and the like. The patients often have the problems of weakened respiratory function, disordered respiratory rhythm, reduced respiratory control capacity and the like, and the stability of the respiratory state of the patients directly influences the curative effect of inhalation administration. Inhalation drug delivery devices (e.g., metered dose aerosols, dry powder inhalers, nebulizers, etc.) currently in clinical use operate based on a fixed drug release profile, lacking the ability to dynamically respond to the patient's real-time respiratory state. The drug absorption efficiency is closely related to the synchronism of the respiratory rhythm of a patient, the ideal drug administration effect requires that the drug is accurately delivered to the respiratory tract in the inspiration phase, and the drug is prevented from being carried out excessively in the expiration phase. The traditional inhalation administration device has no effective respiratory induction and airflow regulation mechanism, when a patient exhales immediately after inhaling, a large amount of atomized liquid medicine just entering the respiratory tract can be directly taken away by the exhaled airflow and cannot be fully deposited on target parts such as alveoli, and clinical data show that the actual utilization rate of the medicine of part of the device is even lower than 20%. Furthermore, existing inhalation drug delivery devices are often in a "passive drug delivery" mode, where the drug may be released continuously or at a non-optimal time, whether the patient is inhaling or exhaling. The medicine released during expiration can not be absorbed, and the medicine particles can be dispersed due to the impact of air flow, so that the effective medicine concentration is further reduced, and the medicine is low in coordination degree, and the administration rhythm and the breathing state are more difficult to coordinate for critical patients. And the gas exhaled by the patient can also reversely enter the atomizer to damage the pressure balance and the drug concentration stability in the atomizer, and influence the quality and the conveying effect of the subsequent atomized drugs. On the other hand, critical patients may suffer from dyspnea or choking risk due to disease fluctuation, and traditional inhalation drug administration devices, especially atomizers, cannot quickly adjust an airflow channel under abnormal conditions in the wearing process of patients, and lack a convenient manual emergency operation mode, which may cause patients to feel suffocation, so that clinical safety requirements are difficult to be met. Disclosure of Invention The invention aims to solve the problems, and provides an inhalation administration device which integrally comprises an atomizer, a mask and a respiration monitoring component, wherein the atomizer is connected with the mask through an administration pipeline, the respiration monitoring component is connected with the mask through a respiration pipeline, a control valve component is further arranged between the respiration monitoring component and the atomizer and used for blocking the connection of the atomizer and the mask when a patient exhales so as to prevent the gas exhaled by the patient from reversely entering the atomizer, and the respiration monitoring component can carry out self-adaptive adjustment according to the expiration intensity of the patient, so that the exhaled gas is exhausted at different speeds, and the expiration intensity can be dynamically monitored in real time. In order to achieve the above purpose, the technical scheme adopted by the invention is as follows: An inhalation delivery device comprising a mask and a nebulizer, the mask and the nebulizer being connected by a delivery conduit, the device further comprising: the respiratory monitoring assembly is connected with the mask through a respiratory pipeline and is used for dynamically monitoring the expiratory strength of a patient in real time and discharging the gas exhaled by the patient; and the control valve assembly is connected with the respiration monitoring assembly and the atomizer and is used for sealing the atomizer from the drug delivery pipeline when a patient exhales gas. Further, the respiration monitoring assembly includes: One end of the connecting seat is connected with the mask through a breath