CN-121987974-A - Bite tissue compensation device for radiotherapy and preparation method thereof

Abstract

The bite tissue compensation device for radiotherapy comprises a bite support and a compensation structure, wherein the bite support comprises a bite part and an inner extension support, the bite part comprises a bite area positioned at the end part, the bite area is used for being matched with teeth in an oral cavity, the inner extension support extends from the bite part to the interior of the oral cavity, the inner extension support comprises a rotating plate, the compensation structure comprises a compensation area used for being attached to a tumor area in the oral cavity, and the compensation structure further comprises a switching cavity used for accommodating the rotating plate so as to fix the compensation structure and the inner extension support. Also provides a preparation method of the bite tissue compensation device for radiotherapy. The device and the method can ensure the consistency and the accuracy of each radiotherapy treatment process, rapidly realize the personalized treatment requirement of patients and achieve better treatment effect.

Inventors

• DU CHENGRUN
• LU YIDONG
• PENG ZAILI

Assignees

• 复旦大学附属肿瘤医院
• 上海黑焰医疗科技有限公司

Dates

Publication Date

20260508

Application Date

20260205

Claims (10)

1. 1. A bite tissue compensation device for radiation therapy, comprising: A bite support comprising a bite portion including a bite region at an end portion for engaging teeth in an oral cavity and an inner extension support extending from the bite portion toward an interior of the oral cavity, the inner extension support comprising a swivel plate, and The compensating structure comprises a compensating area for being attached to a tumor area in the oral cavity, and further comprises an adapter cavity for accommodating the adapter plate so as to fix the compensating structure and the inner extension bracket.
2. 2. The bite tissue compensation device for radiation therapy of claim 1, wherein said compensation structure is of elastomeric material, said compensation structure further comprising a communication port communicating between said adapter cavity and an exterior of the compensation structure.
3. 3. The bite tissue compensation device for radiation therapy of claim 2, wherein said compensation structure is silica gel.
4. 4. The bite tissue compensation device for radiation therapy of claim 1, wherein said compensation structure further comprises a tongue depressor region.
5. 5. The bite tissue compensation device for radiation therapy of claim 1, wherein said bite region comprises upper and lower bites for mating with upper and lower teeth, respectively, in said oral cavity.
6. 6. The bite tissue compensation device for radiation therapy according to claim 1, wherein said bite support further comprises an outer extension support extending from said bite portion to an outside of the mouth as a grip portion, said outer extension support being disposed non-parallel to said bite region.
7. 7. A method for producing a bite tissue compensation device for radiation therapy according to any one of claims 1 to 6, characterized by comprising a bite stent production step and a compensation structure production step, The preparation steps of the compensation structure comprise: Acquiring CT scanning data of a patient in a mouth opening state; Establishing a die opening internal structure according to the CT scanning data, determining the form of a compensation area of the compensation structure, and obtaining a compensation structure model; Manufacturing a compensation structure according to the compensation structure model; After the form of the compensation area is determined, the seaming bracket is prepared, and the method comprises the following steps: obtaining a bite bracket model according to the tooth shape of a patient; Preparing the seaming bracket according to the seaming bracket model; the adapter plate of the seaming bracket extends into the adapter cavity of the compensation structure to connect the seaming bracket and the compensation structure.
8. 8. A method of preparing a bite tissue compensation device for radiation therapy as defined in claim 7, Preparing a silica gel pouring mold according to the compensation structure model and the seaming bracket; the compensation structure is prepared by using a silica gel pouring mould through a silica gel pouring production mode.
9. 9. The method of preparing a bite tissue compensation device for radiation therapy according to claim 7, wherein said bite structure is prepared according to said bite stent model using 3D printing.
10. 10. The method of preparing a bite tissue compensation device for radiation therapy according to claim 7, wherein an angle between an external stent and a bite portion is determined based on said open state, and a shape of said bite region is determined based on said tooth shape.

Description

Bite tissue compensation device for radiotherapy and preparation method thereof Technical Field The invention relates to the technical field of medical instruments, in particular to the field of tissue compensation instruments for radiotherapy. Background Radiation therapy is widely used in the treatment of oral maxillofacial malignancies, but the radiation Effect is affected by the Build-up Effect. The build-up effect refers in particular to the phenomenon that after high-energy rays (such as X-rays, electron beams) enter the human body, the dose gradually increases with increasing depth, forming a build-up region, but after reaching a certain depth, the dose reaches a maximum value and then gradually decays. Based on the effect, the target irradiation object can absorb better radiation dose when being positioned in an ideal distribution area, so as to obtain better radiation treatment effect. However, the tumor outside the skin or in the superficial area is difficult to be positioned at the depth required by the ideal distribution area due to the shallower self-position, so that the tumor in the superficial oral cavity cannot be effectively irradiated, and the radiotherapy effect is poor. For this reason, tissue compensators (Bolus) are often used, which cover the surface of the target area of the superficial tumor, to adjust the depth and thus the dose of radiation to which the superficial tumor is subjected. However, if the tissue compensator does not fit well to the surface of the superficial tumor target, additional empty areas are created, air bubbles and gaps appear, which can significantly affect the effectiveness of the radiation treatment. Chinese patent CN110575625A provides a method for producing a tissue equivalent compensator for radiotherapy, which comprises obtaining a three-dimensional data model of a portion of a patient to be radiotherapy, reversely calculating a three-dimensional data model of a tissue equivalent compensator complementary to the portion of the patient to be radiotherapy according to the three-dimensional data model of the portion of the patient to be radiotherapy, and 3D printing the tissue equivalent compensator according to the three-dimensional data model. But the placement position of the equivalent compensator also affects the contact tightness between the compensator and the radiotherapy site, thereby affecting the radiotherapy effect. For tumors in the oral cavity, such as tumor areas near the tongue, it is desirable to fit the compensator into the patient's mouth and require the patient to be in an open state for a long period of time. The structure in the oral cavity is complex, so that the compensator cannot be perfectly attached, the position for placing the compensator each time and the angle of the opening of the patient are not fixed for different patients, the oral cavity is stable during treatment, and the oral cavity comprises organs such as teeth, tongues and the like which are easy to move, and the irradiation of radiation treatment to a target area is unstable, so that the treatment effect is affected. Korean patent KR102776565B1 provides an oral device for radiation therapy, which includes a plate portion, a handle portion, a preset plate, and a fixing plate. The oral device for radiation therapy is inserted into the mouth of a user, the preset plate is shaped so that upper and lower front teeth of the user can be placed thereon, the fixing plate is used for fixing the tongue of the user during radiation therapy, and the gap forming body is positioned between the incisors and lips of the user to form a gap. The device can separate the normal tissue from the radiation irradiation area during the radiotherapy process, and minimize the problems caused by unnecessary radiation irradiation to the normal tissue. Although this device can effectively press the tongue to separate the normal tissue from the irradiation region, a further placement of the compensator is required. Disclosure of Invention It is an object of the present invention to provide a bite tissue compensation device for radiation therapy. It is another object of the present invention to provide a method of making a bite tissue compensation device for radiation therapy. The bite tissue compensation device for radiotherapy comprises a bite support and a compensation structure, wherein the bite support comprises a bite part and an inner extension support, the bite part comprises a bite area positioned at the end part and used for being matched with teeth in an oral cavity, the inner extension support extends from the bite part to the interior of the oral cavity, the inner extension support comprises an adapter plate, the compensation structure comprises a compensation area used for being attached to a tumor area in the oral cavity, and the compensation structure further comprises an adapter cavity used for accommodating the adapter plate so as to fix the compensation structure and the inner e