CN-121988220-A - Aseptic adding system and aseptic adding method

CN121988220ACN 121988220 ACN121988220 ACN 121988220ACN-121988220-A

Abstract

The invention discloses a sterile adding system and a sterile adding method, wherein the system comprises a first hose, a peristaltic pump, a static mixer, a peristaltic pump, a puncture needle and a material main pipeline, wherein the input end of the first hose is connected with the filled sterile bag and a sterile tank, the output end of the first hose is connected with one side of the peristaltic pump, the input end of the second hose is connected with the other side of the peristaltic pump, the output end of the second hose is connected with one side of the peristaltic pump, material liquid in the peristaltic pump is conveyed to the ultra-clean workbench through the second hose to be subjected to sterile treatment, the puncture needle is arranged in the ultra-clean workbench and is used for conveying the material liquid to the material main pipeline, the static mixer is arranged in the material main pipeline and is used for adding a fixed amount of preset substances into the material liquid to be mixed, and the mixed material liquid flows into a subsequent process. The invention can meet the requirement of aseptic addition compatible with material batch of large size under the working condition of large material batch size difference, and reduce the consumable cost.

Inventors

DONG YANBIN
BA GENNA
GAO WENJUN
HAO HAIJUN
LI HENG
LI YUNFENG
WU JIALI
ZHANG KAISHUAI

Assignees

内蒙古伊利实业集团股份有限公司

Dates

Publication Date: 20260508
Application Date: 20241101

Claims (12)

1. A sterile adding system is characterized by comprising a sterile bag, a sterile tank, a first hose, a second hose, a peristaltic pump, an ultra-clean workbench and a material main pipeline, wherein, The input end of the first hose is connected with the filled sterile bag and the filled sterile tank, and the output end of the first hose is connected with one side of the peristaltic pump; The input end of the second hose is connected with the other side of the peristaltic pump, and the output end of the second hose is connected with one side of the ultra-clean workbench and is used for conveying material liquid in the peristaltic pump to the ultra-clean workbench; The peristaltic pump is used for conveying the material liquid into the ultra-clean workbench through the second hose for aseptic treatment; A puncture needle is arranged in the ultra-clean workbench and connected with the input end of the main material pipeline, and the puncture needle is used for conveying the material liquid to the main material pipeline; The material main pipeline is internally provided with a static mixer, the static mixer is used for adding quantitative preset substances into the material liquid for mixing, and the mixed material liquid flows into the subsequent process.
2. The system of claim 1, wherein the main material line further comprises a first flow meter: The first flowmeter is used for monitoring the flow of the material liquid.
3. The system as recited in claim 2, further comprising: And the PLC controller of the peristaltic pump is used for receiving the flow monitoring result of the material liquid and controlling the driving frequency of the peristaltic pump according to the flow monitoring result, wherein the flow monitoring result of the material liquid is measured according to the first flow meter.
4. The system as recited in claim 2, further comprising: and the second flowmeter is positioned on the second hose and is used for monitoring the flow of the material liquid in the second hose and transmitting the monitoring result to the PLC of the peristaltic pump.
5. The system of claim 1, wherein the peristaltic pump is configured to: and inputting the material liquid in the sterile bag and the sterile tank into a second hose to finish filling of the second hose, wherein no bubbles are ensured in the second hose in the filling process.
6. A method of aseptic adding, characterized in that the method is applied to the aseptic adding system according to any one of claims 1 to 5, the method comprising: filling a first preset batch of material liquid into an aseptic bag to obtain a filled aseptic bag in the aseptic adding process of the material liquid; Connecting the filled sterile bag and the sterile tank with a peristaltic pump through a first hose, starting the peristaltic pump to enable the material liquid in the sterile bag and the sterile tank to flow into a second hose, and conveying the material liquid to an ultra-clean workbench through the second hose to enable the material liquid to flow out into a material main pipeline through a puncture needle head arranged on the ultra-clean workbench; The flow of the material liquid is monitored by adopting a first flow meter in a material main pipeline, the content of a preset substance to be added in the material liquid is determined according to the monitoring result, other quantitative substances are added into the material liquid by adopting a static mixer for mixing, and the mixed material liquid flows into a subsequent process.
7. The method of claim 6, comprising, prior to delivering the material liquid to the ultra clean bench via the second hose: And monitoring the flow of the material liquid in the second hose by adopting a second flowmeter, adjusting the driving frequency of the peristaltic pump according to the monitoring result, and re-monitoring the flow of the adjusted material liquid to obtain a second monitoring result.
8. The method of claim 7, wherein the monitoring of the flow rate of the material liquid by using the first flow meter in the main material pipeline, and determining the content of other substances to be added in the material liquid according to the monitoring result, comprises: monitoring the flow of the material liquid in the material main pipeline by adopting a first flow meter to obtain a first monitoring result; And determining the content of other substances to be added in the material liquid according to the first monitoring result and the second monitoring result.
9. A method of aseptic adding, characterized in that the method is applied to the aseptic adding system according to any one of claims 1 to 5, the method comprising: After filling the material liquid into the sterile bag and the sterile tank, sending a control instruction to the peristaltic pump to start the peristaltic pump, enabling the material liquid in the sterile bag and the sterile tank to flow into a second hose, and conveying the material liquid to the ultra-clean workbench through the second hose so that the material liquid flows out into a material main pipeline through a puncture needle head arranged on the ultra-clean workbench; And acquiring a monitoring result of the first flowmeter on the flow of the material liquid in the material main pipeline, determining the content of a preset substance to be added in the material liquid according to the monitoring result, controlling the static mixer to add quantitative other substances into the material liquid for mixing, and flowing the mixed material liquid into a subsequent process.
10. A computer device comprising a memory, a processor and a computer program stored on the memory and executable on the processor, characterized in that the processor implements the method of claim 9 when executing the computer program.
11. A computer readable storage medium, characterized in that the computer readable storage medium stores a computer program which, when executed by a processor, implements the method of claim 9.
12. A computer program product, characterized in that the computer program product comprises a computer program which, when being executed by a processor, implements the method of claim 9.

Description

Aseptic adding system and aseptic adding method Technical Field The invention relates to the technical field of food material preparation, in particular to a sterile adding system and a sterile adding method. Background This section is intended to provide a background or context to the embodiments of the invention that are recited in the claims. The description herein is not admitted to be prior art by inclusion in this section. The current aseptic mode of adding mostly uses aseptic bag now, when needs big batch of interpolation material, the aseptic form of adding of aseptic bag needs frequent change, has uncontrollable risk such as pollution, and corresponding consumptive material expense cost can continuously increase, and the batch size of material is often unfixed in the practical application occasion, and prior art can't realize the aseptic interpolation that big material batch all is compatible under the great operating mode of batch material batch size difference of same batch. Disclosure of Invention The embodiment of the invention provides a sterile adding system which is used for meeting the requirement of sterile adding compatible with material batches of different sizes under the working condition that the material batches are large in size, and reducing the consumable cost, and comprises a sterile bag, a sterile tank, a first hose, a second hose, a peristaltic pump, an ultra-clean workbench and a material main pipeline; the input end of the first hose is connected with the filled sterile bag and the sterile tank, and the output end of the first hose is connected with one side of the peristaltic pump; The input end of the second hose is connected with the other side of the peristaltic pump, and the output end of the second hose is used for being connected with one side of the ultra-clean workbench and conveying material liquid in the peristaltic pump to the ultra-clean workbench; The peristaltic pump is used for conveying the material liquid into the ultra-clean workbench through the second hose for aseptic treatment; A puncture needle is arranged in the ultra-clean workbench and connected with the input end of the main material pipeline, and the puncture needle is used for conveying the material liquid to the main material pipeline; The material main pipeline is internally provided with a static mixer, the static mixer is used for adding quantitative preset substances into the material liquid for mixing, and the mixed material liquid flows into the subsequent process. The embodiment of the invention also provides a sterile adding method which is applied to the sterile adding system and is used for meeting the requirement of compatible sterile adding of large and small material batches under the working condition of large material batch size difference and reducing the consumable cost, and the method comprises the following steps: filling a first preset batch of material liquid into an aseptic bag to obtain a filled aseptic bag in the aseptic adding process of the material liquid; Connecting the filled sterile bag and the sterile tank with a peristaltic pump through a first hose, starting the peristaltic pump to enable the material liquid in the sterile bag and the sterile tank to flow into a second hose, and conveying the material liquid to an ultra-clean workbench through the second hose to enable the material liquid to flow out into a material main pipeline through a puncture needle head arranged on the ultra-clean workbench; The flow of the material liquid is monitored by adopting a first flow meter in a material main pipeline, the content of a preset substance to be added in the material liquid is determined according to the monitoring result, other quantitative substances are added into the material liquid by adopting a static mixer for mixing, and the mixed material liquid flows into a subsequent process. The embodiment of the invention also provides a sterile adding method which is applied to the sterile adding system and is used for meeting the requirement of compatible sterile adding of large and small material batches under the working condition of large material batch size difference and reducing the consumable cost, and the method comprises the following steps: After filling the material liquid into the sterile bag and the sterile tank, sending a control instruction to the peristaltic pump to start the peristaltic pump, enabling the material liquid in the sterile bag and the sterile tank to flow into a second hose, and conveying the material liquid to the ultra-clean workbench through the second hose so that the material liquid flows out into a material main pipeline through a puncture needle head arranged on the ultra-clean workbench; And acquiring a monitoring result of the first flowmeter on the flow of the material liquid in the material main pipeline, determining the content of a preset substance to be added in the material liquid according to the monitoring result, controllin