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CN-121988417-A - Partition independent cold precipitation preparation instrument

CN121988417ACN 121988417 ACN121988417 ACN 121988417ACN-121988417-A

Abstract

The application relates to the technical field of plasma preparation equipment, and discloses a partition independent cryoprecipitation preparation instrument which comprises a plurality of preparation modules, a water supply system and a control system. The preparation module comprises a water tank for accommodating single frozen plasma bags, wherein the water tank is provided with a water inlet, water bodies among the water tanks of the preparation modules are physically isolated through structures such as partition plates, the water supply system is respectively communicated with the water inlets of the water tanks of the preparation modules, the control system is respectively electrically connected with the water supply system and the preparation modules, and the control system is used for controlling the water supply system to supply water with preset temperature to the water tank of any preparation module so as to melt the plasma in the corresponding frozen plasma bag. The preparation modules are mutually isolated, so that cross contamination can be physically eliminated, and each unit is supported to independently operate.

Inventors

  • LI HAIMIN
  • GAO XIA
  • SHI JIABIN
  • LI CHAOBO
  • LIU KUN
  • YUAN HAO

Assignees

  • 青岛海尔生物医疗科技有限公司
  • 青岛海尔生物医疗股份有限公司

Dates

Publication Date
20260508
Application Date
20260130

Claims (10)

  1. 1.A cold precipitation preparation instrument with independent partition, characterized by comprising the following steps: A plurality of preparation modules (30), wherein the preparation modules (30) comprise water tanks (31) for containing single-bag frozen plasma bags (21), the water tanks (31) are provided with water inlets, and water bodies among the water tanks (31) of the plurality of preparation modules (30) are physically isolated through partition plates (34); a water supply system (40) respectively communicated with water inlets of the water tanks (31) of the plurality of preparation modules (30), and, The control system is electrically connected with the water supply system (40) and the preparation modules (30) respectively; the control system is used for controlling the water supply system (40) to supply water with preset temperature to the water tank (31) of any preparation module (30) so as to melt the blood plasma in the corresponding frozen blood plasma bag (21).
  2. 2. The cryoprecipitation preparation apparatus according to claim 1, wherein the water supply system (40) includes: A refrigerating water tank (411) for supplying water of a preset temperature, and, The pressure equalizing water tank (413) is communicated with the refrigerating water tank (411) through a water supply pipeline (424), and is respectively communicated with the water tanks (31) of the preparation modules (30) through a plurality of water diversion pipelines (421).
  3. 3. The cryoprecipitation preparation apparatus as recited in claim 2, further comprising: The temperature sensors are respectively arranged in the water tanks (31) to obtain the water temperature in the corresponding water tanks (31); The water supply system (40) further comprises: A plurality of water supply solenoid valves (433) provided to the plurality of water diversion pipelines (421), respectively; The control system is further used for independently adjusting the start and stop or the opening of the water supply electromagnetic valve (433) corresponding to the water diversion pipeline (421) according to the water temperature signal fed back by any one of the temperature sensors so as to maintain the water temperature in the corresponding water tank (31) within a preset temperature range.
  4. 4. A cryoprecipitation preparation apparatus as claimed in claim 3, further comprising: a plurality of liquid leakage sensors respectively arranged in the water tanks (31) of the plurality of preparation modules (30); the control device is also electrically connected with the plurality of liquid leakage sensors respectively, and when the liquid leakage sensor of any preparation module (30) is triggered, the preparation module (30) is judged to have liquid leakage, and an isolation program is executed; The isolation procedure includes closing the corresponding water supply solenoid valve (433).
  5. 5. The cryoprecipitation preparation apparatus as recited in claim 4, wherein the water supply system (40) further includes: a collecting tank (412) communicated with the first water outlet of the water tank (31) for receiving water discharged from the water tank (31), and, A water outlet electromagnetic valve (432) arranged at a first water outlet of the water tank (31); The isolation program further comprises the step of controlling the water outlet electromagnetic valve (432) to be fully opened.
  6. 6. The cryoprecipitation preparation apparatus as recited in claim 1, further comprising: A plurality of weighing assemblies (60) respectively arranged corresponding to a plurality of the preparation modules (30), wherein the weighing assemblies (60) are used for acquiring the weight of the frozen plasma bags (21) and the transfer bags (22) contained in the corresponding preparation modules (30); The control system is also electrically connected to a plurality of weighing assemblies (60) respectively, for controlling the cryoprecipitation preparation apparatus to run a preset preparation program according to the weights of the frozen plasma bag (21) and the transfer bag (22).
  7. 7. The cryoprecipitation preparation apparatus as recited in claim 6, wherein the preset preparation program includes: according to the weight of any frozen plasma bag (21), controlling a corresponding preparation module (30) to prepare plasma with preset weight; Wherein the weight of the prepared plasma is directly proportional to the weight of the frozen plasma bag (21).
  8. 8. The cryoprecipitation preparation apparatus as recited in claim 7, further comprising: A plurality of peristaltic modules (50) arranged in correspondence of a plurality of preparation modules (30), and the duct (23) being at least partially fixed to the peristaltic modules (50); Wherein the control system is also electrically connected with a plurality of peristaltic modules (50) respectively; After the drainage preset condition is met, any peristaltic module (50) is controlled to act on the corresponding conduit (23) so as to transfer the blood plasma in the corresponding frozen blood plasma bag (21) to the transfer bag (22) through the conduit (23).
  9. 9. The apparatus according to claim 8, wherein, Controlling the peristaltic module (50) to block the duct (23) in case the weight of the plasma reaches a preset weight.
  10. 10. The apparatus according to any one of claims 1 to 9, wherein, The plurality of preparation modules (30) are divided into two groups, and the two groups of preparation modules (30) are symmetrically arranged at the left half and the right half of the cryoprecipitation preparation apparatus.

Description

Partition independent cold precipitation preparation instrument Technical Field The application relates to the technical field of plasma preparation equipment, in particular to a partition independent cryoprecipitation preparation instrument. Background Cryoprecipitation is a key component in clinical blood transfusion and blood product production, and the preparation process is carried out in a strict low-temperature water bath environment. In order to improve the treatment efficiency, modern blood stations and blood centers usually use multichannel full-automatic preparation equipment to realize parallel treatment of multiple frozen plasma. In the related art, a multi-channel cryoprecipitation preparation apparatus is often designed with one large common water bath or a plurality of simple parallel water tanks. These flume structures typically share the same water circulation system or are physically adjacent but lack an effective isolation barrier between the bodies of water. Each tank is used for containing a bag of frozen plasma, and the cryoprecipitated components are melted and separated by injecting and maintaining a constant temperature of water into the tank. In the process of implementing the embodiments of the present disclosure, it is found that at least the following problems exist in the related art: In the related art, due to the lack of a reliable isolation structure between the plurality of preparation tanks, when a blood bag is broken or leaked, blood components may enter a public water body or spread among different tanks through water body exchange, and there is a serious risk of cross contamination. In addition, the structure is difficult to realize independent and accurate control on the melting environment of each blood bag in a real sense, and the abnormality (such as temperature fluctuation) of one water tank easily affects adjacent units, so that the consistency and the reliability of the preparation process are restricted. Thus, there is a need for a cryoprecipitation apparatus that physically eliminates cross-contamination and supports independent operation of each unit. It should be noted that the information disclosed in the above background section is only for enhancing understanding of the background of the application and thus may include information that does not form the prior art that is already known to those of ordinary skill in the art. Disclosure of Invention The following presents a simplified summary in order to provide a basic understanding of some aspects of the disclosed embodiments. This summary is not an extensive overview, and is intended to neither identify key/critical elements nor delineate the scope of such embodiments, but is intended as a prelude to the more detailed description that follows. The embodiment of the disclosure provides a cold precipitation preparation instrument with independent partitions, a plurality of preparation modules are mutually isolated, cross contamination can be physically eliminated, and independent operation of each unit is supported. The embodiment of the disclosure provides a partition independent cryoprecipitation preparation instrument which comprises a plurality of preparation modules, a water supply system and a control system. The preparation module comprises a water tank for accommodating single frozen plasma bags, wherein the water tank is provided with a water inlet, water bodies among the water tanks of the preparation modules are physically isolated through structures such as partition plates, the water supply system is respectively communicated with the water inlets of the water tanks of the preparation modules, the control system is respectively electrically connected with the water supply system and the preparation modules, and the control system is used for controlling the water supply system to supply water with preset temperature to the water tank of any preparation module so as to melt the plasma in the corresponding frozen plasma bag. In some embodiments, the water supply system includes a refrigeration tank and a pressure equalization tank. The pressure equalizing water tank is communicated with the refrigeration water tank through a water supply pipeline and is respectively communicated with the water tanks of the preparation modules through a plurality of diversion pipelines. In some embodiments, the cryoprecipitation apparatus further includes a plurality of temperature sensors. The temperature sensors are respectively arranged in the water tanks to obtain the water temperature in the corresponding water tanks. The water supply system also comprises a plurality of water supply electromagnetic valves. The control system is also used for independently adjusting the start and stop or opening of the water supply solenoid valve on the corresponding water diversion pipeline according to the water temperature signal fed back by any temperature sensor so as to maintain the water temperature in the correspondi