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CN-121990257-A - Integrated reagent tray

CN121990257ACN 121990257 ACN121990257 ACN 121990257ACN-121990257-A

Abstract

The invention discloses an integrated reagent tray, and relates to the technical field of biochemical inspection equipment. The self-locking mechanism comprises a tray body, reagent hole sites, a semiconductor refrigeration module, a planetary gear self-locking mechanism, a planetary gear, an RFID composite identification base and a honeycomb micro-texture, wherein the graphene heat-conducting silicone grease layers with the thickness of 1.2mm-1.5mm are filled at the cold end and the bottom of the hole sites, the planetary gear self-locking mechanism is arranged at two sides of the tray, the modulus of a sun gear is 0.5, the planetary gear is connected with a titanium alloy reset spring with the rigidity of 2.5N/mm, the RFID composite identification base is arranged at the bottom of the hole and wraps a waterproof layer containing 3.5% -4.2% of nano silicon dioxide, and the honeycomb micro-texture with the side length of 0.1mm is etched at the inner wall of the hole. According to the invention, through multidimensional collaborative design of extreme parameters, the centrifugal resonance error of the instrument is eliminated, micron-sized dynamic locking and extreme temperature control are realized, reagent wall hanging and corrosion-resistant pain points are thoroughly solved, and the automatic sample adding precision is greatly improved.

Inventors

  • WANG XINYUAN
  • Yin Yujiang
  • LIU YOUPENG
  • SHEN KEKE

Assignees

  • 杭州天涅检测技术有限公司

Dates

Publication Date
20260508
Application Date
20260331

Claims (9)

  1. 1. An integrated reagent tray comprises a rectangular tray body (1) and a plurality of reagent hole sites (2) arranged on the top surface of the tray body (1) in an array manner, The reagent tray is characterized by further comprising a semiconductor refrigeration module (3) embedded in the inner bottom surface of the tray body (1), wherein the semiconductor refrigeration module (3) comprises a Peltier element made of bismuth telluride, and a graphene heat-conducting silicone grease layer (4) with the thickness of 1.2-1.5 mm is filled between the cold end of the Peltier element and the bottom of the reagent hole site (2); The planetary gear self-locking mechanism (5) is arranged on two sides of the tray body (1) and is used for being fixed with an external biochemical analyzer, the planetary gear self-locking mechanism (5) comprises a central sun gear (51), three evenly distributed planetary gears (52) and an outer gear (53), wherein the modulus of the central sun gear (51) is 0.5, the number of teeth is 12, the pressure angle is 20 degrees, and a central shaft of the planetary gear (52) is connected with a titanium alloy reset spring (54) with the rigidity coefficient of 2.5N/mm; The RFID composite identification base (6) is integrally formed at the bottommost part of each reagent hole site (2), a polyurethane waterproof layer is wrapped outside the RFID composite identification base (6), and nano silicon dioxide particles with mass fraction of 3.5% -4.2% and a silane coupling agent KH-550 with mass fraction of 0.5% -0.8% are doped in the waterproof layer; The surface wall hanging prevention structure is characterized in that each reagent hole site (2) is provided with a honeycomb micro-texture (7) in an etching mode on the inner side wall, the single side length of the honeycomb micro-texture (7) is 0.1mm, the depth is 0.05mm, and the micro-protrusion distance between two adjacent honeycomb units is 0.02mm.
  2. 2. The integrated reagent tray according to claim 1, wherein the tray body (1) is made of a blend of polycarbonate and glass fiber, wherein the mass ratio of the glass fiber is 18% -20%, and an antioxidant 1010 accounting for 1.5% of the total mass is added into the blend.
  3. 3. The integrated reagent tray of claim 1, wherein a miniature radiator fan is connected below the hot end of the semiconductor refrigeration module (3), the miniature radiator fan is provided with 5 sickle-shaped blades which are asymmetrically distributed, the windward inclination angle of each blade is 16.5 degrees, and the air exhaust inclination angle is 22.3 degrees.
  4. 4. An integrated reagent tray according to claim 1, characterized in that the four top corners of the tray body (1) are provided with an anti-collision chamfer, the radius R of the chamfer is 4.5mm, and the chamfer surface is coated with a polytetrafluoroethylene wear-resistant coating with the thickness of 0.02mm-0.03 mm.
  5. 5. The integrated reagent tray according to claim 1, wherein four groups of wavy shock pads (9) distributed in an array are arranged on the bottom surface of the tray body (1), the wavy shock pads (9) are made of foaming polyurethane, the foaming multiplying power is 15-20 times, and the height difference between the wave crest and the wave trough is 1.2mm.
  6. 6. The integrated reagent tray according to claim 1, wherein the front end face of the tray body (1) is embedded with an RGB status indicator light band, the outside of the light band is covered with an epoxy resin light-scattering cover with 85% -88% light transmittance, and the surface of the light-scattering cover is provided with a V-shaped light guide groove with an included angle of 60 degrees.
  7. 7. An integrated reagent tray according to claim 1, wherein the top edge of the reagent well site (2) is provided with a ring-shaped bead (11), the cross section of the ring-shaped bead (11) is semicircular, the radius of the bead is 0.8mm, and the bead is used for forming interference fit with a sealing gasket of an external reagent bottle.
  8. 8. The integrated reagent tray as set forth in claim 1, wherein the top surface of the tray body (1) is further provided with grid-shaped liquid draining guide grooves (12), the bottom of each liquid draining guide groove (12) is provided with a drain slope inclined to the rear of the tray body (1), and the drain slope is 3.5-4.0 degrees.
  9. 9. An integrated reagent tray as claimed in claim 8, wherein the inner surface of the drainage channel (12) is coated with a hydrophilic coating of titanium dioxide such that the contact angle of water drops on the surface is less than 15 degrees.

Description

Integrated reagent tray Technical Field The invention relates to the technical field of medical and biochemical inspection equipment, in particular to an integrated reagent tray. Background In the field of In Vitro Diagnostics (IVD) such as biochemical analysis, immunoluminescence, nucleic acid detection, etc., a reagent tray is a core component for carrying containers such as reagent bottles, test tubes, etc. In the operation process of an automatic analysis instrument, the reagent tray not only needs to provide physical support, but also often needs to be matched with the instrument to finish multiple functions such as refrigeration and fresh-keeping, reagent allowance monitoring, information reading and the like. The conventional reagent tray has the technical defects that firstly, in the aspect of temperature control, the conventional refrigeration base is generally conducted by adopting common silicone grease, the heat conduction is limited by a smearing process, the heat resistance is large, the silicone grease is easy to dry and shift under long-term high-frequency vibration, so that the refrigeration efficiency is attenuated, secondly, the conventional reagent tray and a locking mechanism of a biochemical instrument are generally simple buckles or bolts, tiny displacement resonance is easy to generate when the instrument performs high-speed centrifugation or sample needle puncture, so that the sample injection precision is influenced, thirdly, in the use process, a reagent is occasionally dropped into a reagent hole, a highly corrosive biochemical reagent is extremely easy to damage an RFID chip reading module at the bottom, residual reagent on the hole wall is difficult to clean, and fourthly, the hole wall is smooth, and a 'cylinder effect' is often generated because gas cannot be discharged when the reagent bottle is inserted, so that the reagent bottle cannot be inserted into the bottom. Therefore, there is a need in the art for a reagent tray that solves the above-described multiple technical problems, and has extremely high integration and stability. Disclosure of Invention In order to overcome the defects of the prior art, the invention provides the integrated reagent tray which is highly integrated, has extremely strong structural stability, accurate temperature control and excellent corrosion and wall hanging resistance. The technical scheme is that the integrated reagent tray comprises a rectangular tray body and a plurality of reagent hole sites arranged on the top surface of the tray body in an array mode, and is characterized by further comprising: The semiconductor refrigeration module is embedded into the inner bottom surface of the tray body and comprises a Peltier element made of bismuth telluride, and a graphene heat-conducting silicone grease layer with the thickness of 1.2-1.5 mm is filled between the cold end of the Peltier element and the bottom of the reagent hole site; the planetary gear self-locking mechanism is arranged on two sides of the tray body and used for being fixed with an external biochemical analyzer and comprises a central sun gear, three evenly distributed planetary gears and an external gear ring, wherein the modulus of the central sun gear is 0.5, the number of teeth is 12, the pressure angle is 20 degrees, and a central shaft of the planetary gear is connected with a titanium alloy reset spring with the rigidity coefficient of 2.5N/mm; The RFID composite identification base is integrally formed at the bottommost part of each reagent hole site, a polyurethane waterproof layer is wrapped outside the RFID composite identification base, and nano silicon dioxide particles with mass fraction of 3.5% -4.2% and a silane coupling agent KH-550 with mass fraction of 0.5% -0.8% are doped in the waterproof layer; The surface wall hanging prevention structure is characterized in that each reagent hole site is etched with a honeycomb micro-texture on the inner side wall, the single side length of the honeycomb micro-texture is 0.1mm, the depth is 0.05mm, and the micro-protrusion distance between two adjacent honeycomb units is 0.02mm. Preferably, the tray body is made of a blend of polycarbonate and glass fiber, wherein the mass ratio of the glass fiber is 18% -20%, and the antioxidant 1010 accounting for 1.5% of the total mass is added. Preferably, a micro cooling fan is connected below the hot end of the semiconductor refrigeration module, the micro cooling fan is provided with 5 sickle-shaped fan blades which are asymmetrically distributed, the windward inclination angle is 16.5 degrees, and the exhaust inclination angle is 22.3 degrees. Compared with the prior art, the invention has the following beneficial effects: 1. the invention breaks through the bottleneck of the conventional heat conduction material by limiting the graphene heat conduction silicone grease layer with the thickness of 1.2mm-1.5 mm. The specific thickness not only ensures the continuity of the phon