CN-121992475-A - Photo-thermal system containing chiral multilevel structure and application thereof

CN121992475ACN 121992475 ACN121992475 ACN 121992475ACN-121992475-A

Abstract

The invention relates to the technical field of biological nano materials, in particular to a polarized light-controlled chiral multilevel structure photo-thermal system and application thereof. The chiral material can selectively absorb, scatter or rotate light with a specific polarization direction, so that the chiral material can be used as a polarized light modulation device, and a chiral multilevel structure photo-thermal system is further constructed. Because the hydrothermal reaction is adopted to form a chiral multilevel structure photo-thermal system, the obtained product has controllable size and uniform surface morphology, and is easy to be amplified and applied to mass production. In addition, the obtained product has large specific surface area and chiral multilevel structure.

Inventors

ZHOU CHAO
XU BINBIN
FAN CUNYI
LI MENGRU
JI YONGFENG
YANG AI
OUYANG YUANMING
YU SHIYANG
LIU SHEN
CHEN SHUAI

Assignees

上海市第六人民医院

Dates

Publication Date: 20260508
Application Date: 20241101

Claims (10)

1. The chiral multistage structure photo-thermal platform comprises a precursor, a chiral inducer, a second component, a substrate and/or a nucleation control agent, wherein the precursor is a raw material of a photo-thermal material and is selected from one or more of a soluble molybdenum source, a soluble iron source, a soluble barium source, a soluble bismuth source, a soluble copper source, a soluble zinc source, a soluble antimony source, a soluble gold source, a soluble strontium source, a soluble titanium source, a soluble magnesium source, a soluble silver source, a soluble sulfur source and/or carbon, the second component is selected from one or more of a soluble phosphorus source, a soluble sulfur source, a soluble carbon source, a soluble titanium source and/or a soluble bromine source, and the chiral multistage structure photo-thermal platform is further constructed by adopting a chiral molecule induced coordination in-situ self-assembly method by selecting the raw material of a synthetic photo-thermal material as the precursor.
2. The chiral multi-stage structure photo-thermal platform according to claim 1 is one or more selected from the group consisting of a chiral multi-stage structure molybdenum disulfide photo-thermal platform, a chiral multi-stage structure iron sulfide photo-thermal platform, a chiral multi-stage structure copper sulfide photo-thermal platform, a chiral multi-stage structure zinc sulfide photo-thermal platform, a chiral multi-stage structure magnesium sulfide photo-thermal platform, a chiral multi-stage structure silver sulfide photo-thermal platform, a chiral multi-stage structure antimony sulfide photo-thermal platform, a chiral multi-stage structure manganese sulfide photo-thermal platform, a chiral multi-stage structure strontium sulfide photo-thermal platform, a chiral multi-stage structure barium sulfide photo-thermal platform, a chiral multi-stage structure silver metal photo-thermal platform, a chiral multi-stage structure metal gold photo-thermal platform, a chiral multi-stage structure platinum photo-thermal platform, a chiral multi-stage structure metal palladium photo-thermal platform, and a chiral multi-stage structure carbon photo-thermal platform, wherein the chiral multi-stage structure photo-thermal platform comprises D-COHPs, L-COHPs and Racemic micro-structure photo-thermal platforms, and the micro-structure micro-thermal platforms of the chiral multi-stage structure photo-thermal platforms are assembled to form a spiral stack to form a spiral photo-stack.
3. A method for preparing the chiral multilevel structured photothermal platform according to claim 1, the method comprising the steps of: s1, dissolving a precursor, namely a raw material of a photo-thermal material, in water to form a solution A; S2, dissolving a chiral inducer in water to form a solution B; S3, dissolving the second component and the nucleation control agent in water to form a solution C; s4, rapidly adding the solution B into the solution A to form a mixed solution, and continuously stirring for 5-70 minutes to obtain an AB mixed solution; S5, slowly dripping the solution C into the AB mixed solution to form a mixed reaction solution, and continuously stirring for 5-50 minutes; S6, transferring the mixed reaction liquid into a reaction kettle, adding the pretreated substrate, reacting for 2-24 hours at 80-180 ℃, cooling, taking out the substrate, washing and drying to obtain the chiral multilevel structure photo-thermal platform.
4. A chiral multilevel structured photothermal platform as recited in claims 1-3, the soluble gallium source being selected from one or more of gallium chloride, gallium bromide, gallium iodide, gallium fluoride, gallium nitride, gallium sulfate, gallium phosphide, gallium oxide, and/or gallium selenide; the soluble molybdenum source is selected from one or more of ammonium molybdate, sodium molybdate, magnesium molybdate, zinc molybdate, ammonium dimolybdate, iron molybdate, lead molybdate, copper molybdate, sodium paramolybdate, ammonium tetramolybdate and/or ammonium dimolybdate; the soluble iron source is selected from one or more of ferrous sulfate heptahydrate, ferric chloride, ferric nitrate, ferric oxalate and/or ferric phosphate, the soluble barium source is selected from one or more of barium sulfate, barium chloride, barium nitrate, barium carbonate, barium oxalate, barium acetate, barium phosphate, barium tungstate and/or barium titanate, the soluble bismuth source is selected from one or more of bismuth nitrate pentahydrate, bismuth sulfate, bismuth chloride, bismuth oxalate and/or bismuth acetate, the soluble copper source is selected from one or more of copper chloride, copper sulfate, copper nitrate, copper oxalate, copper tungstate, copper acetate and/or copper phosphate, the soluble strontium source is selected from one or more of strontium nitrate, strontium chloride, strontium oxalate, strontium titanate, strontium sulfate and/or strontium carbonate, the soluble titanium source is selected from one or more of tetra-n-butyl titanate, titanium acetylacetonate, tetraisopropyl titanate, titanium chloride, titanium sulfate, sodium carbonate, potassium titanate and/or ammonium carbonate, the soluble silver source is selected from silver nitrate, silver sulfate, silver bromide, silver iodide, magnesium iodide and/or magnesium nitrate, the soluble silver nitrate, magnesium nitrate and/or magnesium nitrate, the soluble silver nitrate and/or magnesium nitrate is selected from one or magnesium nitrate, oxalate The soluble phosphorus source is selected from one or more of diammonium hydrogen phosphate, dipotassium hydrogen phosphate and/or disodium hydrogen phosphate, the soluble sulfur source is selected from one or more of thioacetamide, sodium sulfide, sulfuric acid, sodium sulfate, potassium sulfate, ammonium sulfate, thiourea, mercaptan, thioether and/or sulfate, the soluble carbon source is selected from one or more of ammonium carbonate, sodium carbonate, potassium carbonate, sodium bicarbonate, potassium bicarbonate and/or ammonium bicarbonate, and the soluble bromine source is selected from one or more of sodium bromide, potassium bromide, hydrogen bromide, ammonium bromide, zinc bromide, copper bromide and/or ferrous bromide.
5. A photo-thermal platform with a chiral multilevel structure according to claim 1-3, wherein the chiral inducer is one or more of chiral amino acid, chiral organic acid, chiral saccharide, chiral alcohol and the like, the chiral amino acid is one or more of histidine, arginine, lysine, isoleucine, phenylalanine, leucine, tryptophan, alanine, methionine, proline, cysteine, aspartic acid, valine, serine, glutamine, tyrosine, aspartic acid, glutamic acid and threonine, the chiral organic acid is one or more of tartaric acid, malic acid and lactic acid, the chiral saccharide is one or more of glucose, fructose, galactose, ribose, deoxyribose, furanose, pyranose, maltose, sucrose and lactose, the chiral alcohol comprises one or more of mannitol, xylitol, sorbitol, paclitaxel, resveratrol, phyllopyranol, (R) - (+) -1-phenyl-1-propanol, (S) - (-) -1-phenyl-1-propanol and/or phenylpropenol, and/or ginkgo-amine, and/or the chiral alcohol is one or more of mannitol, xylitol, sorbitol, paclitaxel and paclitaxel.
6. A chiral multi-stage photothermal platform according to claims 1-3, said nucleation control agent being selected from one or more of urea, sodium dodecyl benzene sulfonate, sodium dodecyl sulfate and/or sodium dodecyl benzene sulfonate.
7. The chiral multistage structured photo-thermal platform according to claim 1-3, wherein the supporting substrate is selected from any one of an activated mica sheet, an iron sheet, a titanium alloy sheet, a magnesium alloy sheet, a glass sheet, a quartz sheet, an FTO sheet, an ITO sheet, a silicon sheet, a copper sheet or a nickel sheet, and the thickness of the supporting substrate is 0.1-1 mm.
8. The photo-thermal system with the chiral multilevel structure comprises a light source and the photo-thermal platform with the chiral multilevel structure as claimed in claim 1, wherein the light source is a polarized light luminous device and comprises a laser and a circular polarized light regulator, the photo-thermal system with the chiral multilevel structure realizes heat generation intelligent regulation and control through polarized light, the polarized light comprises circular polarized light and linear polarized light, and the circular polarized light comprises left circular polarized light and right circular polarized light.
9. The photothermal system comprising a chiral multistage structure as claimed in claim 8, said light source comprising a laser having a wavelength selected from 656-2000nm, preferably 808nm, preferably 915nm, preferably 1064nm, preferably 1550nm.
10. The photo-thermal system with the chiral multi-level structure according to claim 8, wherein the photo-thermal system with the chiral multi-level structure is selected from one or more of a molybdenum disulfide photo-thermal system with the chiral multi-level structure, a ferric sulfide photo-thermal system with the chiral multi-level structure, a copper sulfide photo-thermal system with the chiral multi-level structure, a zinc sulfide photo-thermal system with the chiral multi-level structure, a magnesium sulfide photo-thermal system with the chiral multi-level structure, a silver sulfide photo-thermal system with the chiral multi-level structure, an antimony sulfide photo-thermal system with the chiral multi-level structure, a manganese sulfide photo-thermal system with the chiral multi-level structure, a strontium sulfide photo-thermal system with the chiral multi-level structure, a barium sulfide photo-thermal system with the chiral multi-level structure, a silver metal photo-thermal system with the chiral multi-level structure, a platinum photo-thermal system with the chiral multi-level structure, a palladium photo-thermal system with the chiral multi-level structure and a carbon photo-thermal system with the chiral multi-level structure, wherein the photo-thermal system with the chiral multi-level structure comprises D-COHPs, L-COHPs and Racemic.

Description

Photo-thermal system containing chiral multilevel structure and application thereof Technical Field The invention relates to the technical field of biological nano materials, in particular to a polarized light-controlled chiral multilevel structure photo-thermal system and application thereof. Background The photo-thermal micro-nano glucoside compound, composition and intermediate have excellent photo-thermal conversion capability based on photo-thermal effect, and through years of development, the photo-thermal micro-nano material is more and more in variety and mainly comprises metal nano material, carbon nano material, conjugated polymer nano material and the like (Yang Hao, zhang Zhijiang, liu Cong and the like; photo-thermal micro-nano material research progress [ J ]. Laser journal, 2022,43 (12): 1-7.), and has been widely applied to the fields of medicine, environment, energy and the like. The application principle of the photo-thermal micro-nano materials is photo-thermal effect, and researches show that the materials realize photo-thermal conversion through different mechanisms, such as plasmon resonance, non-radiative relaxation and the like (Lu,Qichen and Xun Wang."Recent Progress of Sub-Nanometric Materials in Photothermal Energy Conversion."Advanced Science 9(2021):n.pag.)., wherein the photo-thermal micro-nano materials have surface plasmon resonance and have high-efficiency optical coupling characteristics, the heat generated by the photo-thermal micro-nano materials under the same light condition is tens to thousands times that of macroscopic materials, extremely high temperature can be generated, and in addition, the surface plasmon resonance can be regulated and controlled by regulating and controlling the material components, the size and the structure of the photo-thermal micro-nano materials, so that different experimental requirements can be matched. These materials achieve heating of the surrounding environment or therapeutic action on a specific target by absorbing light of a specific wavelength, converting their energy into thermal energy. The research hot spot of the current photo-thermal micro-nano material is the research and development of novel photo-thermal materials and the application in the new field. Chiral materials refer to materials having a chiral structure, that is, their molecular or crystal structures have a non-coincident mirror image relationship in space. This chiral structure gives chiral materials many special properties and applications. In particular, the interaction relationship between chiral materials and light, such as optical applications, galvanometers, optical filters, optical devices, etc., makes chiral materials widely used in the optical field. Since the molecular or crystal structures of chiral materials have non-coincident mirror image relationships, their interactions with light exhibit some unique properties such as optical rotation, cyclic dichroism, chiral optical effects, optical signal processing, and the like. Among them, optical rotation, that is, optical rotation effect, which rotates the polarization direction of light passing through them, is one of important manifestations of interaction between chiral materials and light. Circular dichroism, meaning that chiral materials exhibit circular dichroism when absorbing, scattering or transmitting light, i.e. exhibit different absorption or scattering properties for light of different polarization directions, can be used to study the structure and properties of chiral materials and is also widely used in chemical and biological fields. Chiral optical effects refer to some special optical effects that occur when chiral materials interact with chiral light, such as circular dichroism, cross-sectional optical rotation effects, and the like. These effects not only help to understand the structure and properties of chiral materials, but also can be used to develop new optics and sensors. Optical signal processing, referring to the optical properties of chiral materials, may also be used for optical signal processing and information storage, such as the construction of optical memory devices or optical logic gates using chiral materials. In summary, these properties and effects provide a basis and potential for their use in the optical field. The photo-thermal micro-nano material has wide research and application prospects, but also has some challenges, such as improving photo-thermal conversion efficiency, enhancing stability and biocompatibility of the material, realizing large-scale production and the like. Future research needs to be deeply explored in the aspects of material design, synthesis, application and the like so as to realize the wide application of the photo-thermal micro-nano material in various fields. The chiral material can intelligently regulate and control the light in the aspects of light absorption, transmission, scattering, polarization and the like. The polarized light regu