Search

CN-121994793-A - High-throughput digital scanning and intelligent analysis device for lymphopoiesis pathological section

CN121994793ACN 121994793 ACN121994793 ACN 121994793ACN-121994793-A

Abstract

The invention relates to the technical field of pathological section scanning, and particularly discloses a high-throughput digital scanning and intelligent analysis device for lymphopoiesis pathological sections, which comprises a lower shell, wherein a base is arranged on the lower shell, a collecting bin and an upper bin are respectively arranged on two sides of the top of the base, sliding guide rail grooves and material openings are respectively formed in the collecting bin and the upper bin, a plurality of groups of screw rod assemblies are arranged on the base, a scanning assembly is arranged in the middle of each group of screw rod assemblies, a camera is arranged at the bottom of the scanning assembly, a control assembly and a central fixed disc are arranged at the bottom of the camera on the base, and a plurality of clamping blocks are arranged on the central fixed disc.

Inventors

  • CHEN JIANRONG

Assignees

  • 诸暨市人民医院

Dates

Publication Date
20260508
Application Date
20260316

Claims (10)

  1. 1. A high-throughput digital scanning and intelligent analyzing device for lymphopoiesis pathological sections comprises a lower shell (1) and is characterized in that the lower shell (1) comprises a base (101), a collecting bin (102) and an upper bin (103) are respectively arranged on two sides of the top of the base (101), sliding guide rail grooves (104) and a material opening (105) are formed in the collecting bin (102) and the upper bin (103), a plurality of groups of screw components (5) are mounted on the base (101), a scanning component (6) is mounted in the middle of each of the plurality of groups of screw components (5), a control component (4) and a central fixing disc (11) are mounted below the scanning component (6) on the base (101), a plurality of clamping blocks are arranged on the central fixing disc (11), a driving motor is mounted at the bottom of the control component (4), and a second push rod (10) is mounted at the top of the control component (4).
  2. 2. The high-throughput digital scanning and intelligent analyzing device for lymphopoiesis pathological sections according to claim 1, wherein the control assembly (4) consists of a rotating disc (401) and a control arc plate (403), the control arc plate (403) is arranged on the rotating disc (401) through a connecting plate, a toothed plate (404) is arranged on the outer side of the rotating disc (401), two groups of sliding material grooves (402) are formed in the top of the rotating disc (401), the two groups of sliding material grooves (402) are distributed in an obtuse angle, and the sliding material grooves are respectively communicated with a material opening (105) of an upper material bin (103) or a collecting material bin (102) before and after rotation.
  3. 3. The high-throughput digital scanning and intelligent analyzing device for lymphopoiesis pathological sections, which is disclosed in claim 2, is characterized in that a plurality of functional stations are arranged inside the rotating disc (401), each functional station comprises a cleaning station, a thickness measuring station and a scanning station, a miniature rotating brush is arranged at the cleaning station, the surface is cleaned when a glass slide enters, a laser displacement sensor is arranged at the thickness measuring station, and a miniature dip angle motor is arranged at the scanning station.
  4. 4. The high-throughput digital scanning and intelligent analysis device for lymphopoiesis pathological section according to claim 1, wherein the front surfaces of the collecting bin (102) and the feeding bin (103) are provided with control contacts (8), and when the control arc plate (403) rotates to be aligned with the collecting bin (102) or the feeding bin (103), the end part of the control arc plate (403) contacts with the control contacts (8) to trigger corresponding feeding, scanning or discharging procedures.
  5. 5. The high-throughput digital scanning and intelligent analysis device for lymphopoiesis pathological section according to claim 4, wherein the control contact (8) is a multifunctional electrical interface, and is integrated with a power supply contact and a data contact for supplying power to and transmitting data from an active device in the rotating disk (401).
  6. 6. The high-throughput digital scanning and intelligent analysis device for lymphopoiesis pathological sections according to claim 1, wherein the screw assembly (5) comprises a threaded rod (501), a first gear (502) is fixedly connected to the threaded rod (501), the first gear (502) is meshed with a toothed plate (404), a stabilizing plate (503) is mounted on the threaded rod (501), and a plurality of stabilizing plates (503) are jointly mounted on the side face of the scanning assembly (6).
  7. 7. The high-throughput digital scanning and intelligent analyzing device for lymphopoiesis pathological sections according to claim 1, further comprising a storage tray (7), wherein the storage tray (7) comprises a movable main frame (701), a plurality of feeding helical teeth (702) are arranged on the movable main frame (701), a glass slide groove (705) is arranged in the middle of the movable main frame (701), and a first fulcrum (703) and a second fulcrum (704) are fixedly connected to the side face of the movable main frame (701).
  8. 8. The high-throughput digital scanning and intelligent analyzing device for lymphopoiesis pathological sections according to claim 1, further comprising a commodity shelf (3), wherein the commodity shelf (3) comprises a retractable main board (301), a plurality of groups of movable supporting rods (302) are arranged on the retractable main board (301), each group of movable supporting rods (302) is arranged on the retractable main board (301) through a hinge, and each movable supporting rod (302) is provided with a movable clamping groove (303).
  9. 9. The high-throughput digital scanning and intelligent analyzing device for lymphopoiesis pathological section of claim 1, wherein the collecting bin (102) is internally provided with a lifting push rod for driving the object placing tray (7) to collect and store in a classified manner in a multi-layer stack inside the collecting bin (102).
  10. 10. The high-throughput digital scanning and intelligent analysis device for lymphopoiesis pathological section according to claim 1, wherein the scanning assembly (6) is internally provided with an analysis module for automatically completing cell detection, classification and counting.

Description

High-throughput digital scanning and intelligent analysis device for lymphopoiesis pathological section Technical Field The invention relates to the technical field of pathological section scanning, in particular to a high-throughput digital scanning and intelligent analysis device for lymphopoiesis pathological sections. Background Diagnosis of lymphohematopoietic disorders (e.g., lymphomas, leukemias) is highly dependent on morphological observation and immunohistochemical analysis of pathological sections. The lymphoid tissue has the characteristics of extremely dense cells, fragile texture, easy occurrence of wrinkles and dyeing difference, and the like, and has extremely high requirements on slice quality and scanning accuracy. With the development of digital pathology, high throughput slice scanners have been gradually applied to the clinic, but the following problems exist in practical use: Firstly, the existing scanning equipment is insufficient in automation degree, mostly needs to complete operations such as slide feeding, cleaning, bar code inputting and the like manually in single-machine operation, and is difficult to realize whole-course unmanned from slicing to digital image. The pathological technicians need to intervene frequently, so that the efficiency is low, and human errors are easy to introduce; Secondly, the scanning quality is limited by the sample state, the problems of wrinkling, folding, local defocusing and the like of the lymphoid tissue section often exist, the traditional vertical scanning mode is difficult to obtain a complete and clear full-view image, the re-scanning rate is high, and the diagnosis efficiency is influenced; moreover, the existing scanner has single function, lacks preprocessing capability, cannot complete functions of cleaning a slide, measuring thickness, pre-focusing and the like before scanning, and frequently causes the problem of defocusing caused by slide stains or thickness differences in the scanning process; In addition, the existing equipment is disjointed from the follow-up intelligent analysis system, the images are manually exported after scanning is completed and then imported into the analysis system, the process is split, and real-time diagnosis feedback and automatic classification storage are difficult to realize. Disclosure of Invention In order to overcome the defects in the prior art, the invention provides a high-throughput digital scanning and intelligent analysis device for lymphopoiesis pathological sections, which solves the problems in the background art. The invention provides a high-throughput digital scanning and intelligent analyzing device for lymphopoiesis pathological sections, which comprises a lower shell, wherein a base is arranged on the lower shell, a collecting bin and an upper bin are respectively arranged on two sides of the top of the base, sliding guide rail grooves and material openings are respectively formed in the collecting bin and the upper bin, a plurality of groups of screw rod assemblies are arranged on the base, a scanning assembly is arranged in the middle of each of the plurality of groups of screw rod assemblies, a camera is arranged at the bottom of the scanning assembly, a control assembly and a central fixed disc are arranged at the bottom of the camera on the base, a plurality of clamping blocks are arranged on the central fixed disc, a driving motor is arranged at the bottom of the control assembly, and a second push rod is arranged at the top of the control assembly. Further, the inside of the collection bin is provided with a lifting push rod for driving the storage tray to integrally ascend in the collection bin, so that multi-layer stacking collection is realized. The control assembly is further composed of a rotating disc and a control arc plate, the control arc plate is arranged on the rotating disc through a connecting plate, a toothed plate is arranged on the outer side of the rotating disc, two groups of sliding material grooves are formed in the top of the rotating disc and distributed at an obtuse angle, the two groups of sliding material grooves are respectively communicated with a material inlet of a feeding bin or a material inlet of a collecting bin before and after rotation, the second push rod is composed of a hydraulic rod and a push plate, and the height of the push plate is the same as that of the storage disc. Further, the object placing tray comprises a movable main frame, a plurality of feeding helical teeth are arranged on the movable main frame, a slide glass groove is formed in the middle of the movable main frame, slide glass is arranged in the slide glass groove, and a first supporting point and a second supporting point are fixedly connected to the side face of the movable main frame. Further, the screw assembly comprises a threaded rod, a first gear is fixedly connected to the threaded rod, the first gear is connected with the toothed plate in a meshed mode, a stabi