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CN-121995073-A - Sample analyzer

CN121995073ACN 121995073 ACN121995073 ACN 121995073ACN-121995073-A

Abstract

The embodiment of the application provides a sample analyzer, which comprises a shell component, a sample injection mechanism, a reaction device and a detection device, wherein the shell component comprises a surface shell provided with an opening, the sample injection mechanism comprises a sample seat and one or more baffles, the one or more baffles open the opening when the sample seat enters the interior of the shell component from the exterior of the shell component or protrudes from the interior of the shell component to the exterior of the shell component through the opening, the one or more baffles cover the opening when the sample seat is positioned at a sample position to be sucked in the interior of the shell component or a loading position of the sample seat outside the shell component, and the sample seat is positioned at the sample position to be used for placing a sample container to be scheduled to the sample suction position for sucking samples. By arranging one or more baffles to shield the opening of the face shell, the occurrence of the problem that the polluted gas inside the instrument leaks into the external environment and the polluted gas in the external environment enters into the instrument can be effectively reduced.

Inventors

  • GAO ZAIXING
  • WANG TONGYANG
  • WANG CHANGXING

Assignees

  • 深圳迈瑞生物医疗电子股份有限公司

Dates

Publication Date
20260508
Application Date
20251105
Priority Date
20241106

Claims (20)

  1. 1. A sample analyzer, comprising: A housing assembly comprising a face shell provided with an opening; the sample feeding mechanism comprises a sample seat and one or more baffles, wherein the sample seat is used for bearing a sample container, and the sample container is used for containing a sample to be tested; the reaction device is used for providing a reaction place for the mixed solution containing the sample to be tested and the reagent in the reaction container and forming a reaction solution; The detection device is used for detecting the reaction liquid to obtain a detection result of a sample to be detected; Wherein the one or more baffles open the opening when the sample holder enters the interior of the housing assembly from the exterior of the housing assembly through the opening or protrudes from the interior of the housing assembly to the exterior of the housing assembly through the opening; The one or more baffles conceal the opening when the sample holder is positioned at a sample-to-be-aspirated position inside the housing assembly or at a loading position outside the housing assembly, the sample holder being positioned at the sample-to-be-aspirated position to place a sample container to be dispatched to a sample-aspirating position for aspirating a sample, the sample holder being positioned at the loading position to receive a sample container loaded to the sample holder.
  2. 2. The sample analyzer of claim 1, wherein the sample introduction mechanism comprises an unloaded state; In the unloaded state, the sample holder carries a sample container to be recovered, protruding from the interior of the housing assembly to the exterior of the housing assembly through the opening to transport the sample container to be recovered from the interior of the housing assembly to a recovery location external to the housing assembly; The one or more baffles conceal the opening when the sample holder is in a recovery position external to the housing assembly.
  3. 3. The sample analyzer of claim 1, wherein the interior of the housing assembly has a sample compartment having a gas pressure that is less than a gas pressure of the exterior of the housing assembly.
  4. 4. The sample analyzer of claim 1, further comprising a sample dispensing member and a pipetting member disposed on the sample dispensing member, the sample dispensing member for moving the pipetting member between different positions of operation to aspirate or discharge a sample to be measured; The sample analyzer further comprises a pressure detection mechanism and a processor, wherein the pressure detection mechanism is used for detecting the pressure in the pipetting component, and the processor is used for receiving a pressure signal output by the pressure detection mechanism and determining whether the pipetting component leaks according to the pressure signal.
  5. 5. The sample analyzer of claim 1, further comprising a sample dispensing member and a pipetting member disposed on the sample dispensing member, the sample dispensing member for moving the pipetting member between different operational positions to aspirate or discharge a sample to be measured; the sample analyzer further comprises a drip tray which is positioned below the pipetting component and moves along with the pipetting component for holding a sample to be measured which is dripped from the pipetting component.
  6. 6. The sample analyzer of claim 1, further comprising a dispatching mechanism, a clamping mechanism, an open-close cover mechanism, and a suction device; the scheduling mechanism is used for scheduling the sample container to be subjected to sample suction on the sample seat to a cover opening position; The clamping mechanism is used for clamping or loosening the main body of the sample container positioned at the cover opening position; The cover opening and closing mechanism is used for clamping the cover of the sample container at the cover opening position so as to open or close the cover of the sample container; the suction device includes a suction port that is directed toward an opening of a main body of the sample container in the open-cover position.
  7. 7. The sample analyzer of any of claims 1-6, wherein the one or more baffles comprise a first baffle and a second baffle; When the sample seat is positioned at a sample to be sucked in the shell component, the first baffle shields the opening, and the second baffle shields the opening; The second baffle shields the opening and the first baffle shields the opening when the sample holder is in a loading position outside the housing assembly.
  8. 8. The sample analyzer of claim 7, wherein the second baffle is coupled to and moves synchronously with the sample holder; During the process that the sample injection mechanism moves from the inside of the shell assembly to the outside of the shell assembly, the second baffle and the sample seat synchronously move from the inside of the shell assembly to the opening, and the first baffle moves to avoid the opening, so that the sample seat extends out of the shell assembly and the second baffle shields the opening; During the process that the sample injection mechanism moves from the outside of the shell component to the inside of the shell component, the second baffle and the sample seat synchronously move from the opening to the inside of the shell component, so that the sample seat and the second baffle enter the inside of the shell component, and the first baffle moves to cover the opening.
  9. 9. The sample analyzer of claim 7, wherein an inner surface of the face housing has a sealing engagement surface surrounding the opening, the sealing engagement surface for sealing engagement with the first baffle or the second baffle; the first baffle rotates relative to the face shell, and the rotation center line of the first baffle is parallel to the sealing matching surface so as to shield or avoid the opening.
  10. 10. The sample analyzer of claim 9, wherein the rotational travel of the first baffle is greater than 0 ° and no more than 90 °.
  11. 11. The sample analyzer of claim 7, wherein an inner surface of the face housing has a sealing engagement surface surrounding the opening, the sealing engagement surface for sealing engagement with the first baffle or the second baffle; The sample injection mechanism comprises a driving mechanism, wherein the driving mechanism is used for driving the first baffle plate to translate, and translational displacement of the first baffle plate comprises a displacement component in a first direction and a displacement component in a second direction, wherein the first direction is perpendicular to the sealing matching surface, and the second direction is parallel to the sealing matching surface.
  12. 12. The sample analyzer of claim 7, wherein an inner surface of the face housing has a sealing engagement surface surrounding the opening, the sealing engagement surface for sealing engagement with the first baffle or the second baffle; The sample seat and the second baffle move linearly along a first direction, and the first direction is perpendicular to the sealing matching surface; The sample feeding mechanism further comprises a power mechanism, and the power mechanism is used for driving the sample seat and the second baffle to linearly move along a first direction.
  13. 13. The sample analyzer of claim 7, wherein the sample introduction mechanism further comprises a linkage mechanism for linking the first shutter and the second shutter to move the first shutter to avoid the opening during movement of the second shutter from the interior of the housing assembly to the opening or to move the first shutter to shield the opening during movement of the second shutter from the opening to the interior of the housing assembly.
  14. 14. The sample analyzer of claim 13, wherein the sample holder and the second barrier move linearly in a first direction, the sample introduction mechanism further comprising a shaft portion coupled to the first barrier; the linkage mechanism comprises a limiting part and a first reversing assembly, the second baffle and the sample seat are moved to drive the limiting part to linearly move along the first direction, and the first reversing assembly is connected with the limiting part and the shaft part and used for converting the linear movement of the limiting part along the first direction into the rotation of the shaft part and further driving the first baffle to rotate through the shaft part.
  15. 15. The sample analyzer of claim 14, further comprising a carrier and a pedestal; the first baffle, the second baffle and the sample seat are all arranged on the top side of the bearing table; The shaft holder is connected to the carrying table, the shaft holder has at least two shaft holes coaxially arranged in a height direction of the sample analyzer, and the shaft portion rotatably passes through the at least two shaft holes.
  16. 16. The sample analyzer of claim 12 or 14, further comprising a carrier and a rail; the first baffle, the second baffle and the sample seat are all arranged on the top side of the bearing table; The rail extends linearly along a first direction on the top surface of the bearing table, and the rail is used for guiding the linear motion of the sample seat and/or the second baffle along the first direction.
  17. 17. The sample analyzer of claim 14, wherein the sample analyzer comprises a sample cell, The movement stroke of the second baffle plate and the sample seat in the first direction comprises a first stroke section and a second stroke section, wherein the first stroke section is positioned at one side close to the inside of the shell assembly, and the second stroke section is positioned at one side close to the opening; In the first travel section, the elastic piece applies elastic force to the limiting piece in the direction close to the opening, and at least one of the sample seat and the second baffle is abutted against the limiting piece in the first direction under the action of the elastic force so as to enable the second baffle, the sample seat and the limiting piece to be linked; in the second stroke section, the elastic piece is in a natural state, and the sample seat and the second baffle are separated from the limiting piece, so that the linkage mechanism keeps static while the sample seat and the second baffle move.
  18. 18. The sample analyzer of claim 14, wherein the first reversing assembly comprises an annular first flexible drive member, the sample analyzer further comprising a wheel; The two ends of the first flexible transmission piece are wound on the shaft part and the wheel part, the limiting piece is connected with the first flexible transmission piece, and the limiting piece drives the first flexible transmission piece to move so as to drive the shaft part to rotate through the first flexible transmission piece.
  19. 19. The sample analyzer of claim 12, wherein the power mechanism comprises a motor, a second reversing assembly and a connecting structure, the motor has a power output shaft, at least one of the sample holder and the second baffle is connected with the second reversing assembly through the connecting structure, and the second reversing assembly is used for converting rotation of the power output shaft into linear motion of the connecting structure along a first direction, so that the connecting structure drives the sample holder and the second baffle to linearly move along the first direction.
  20. 20. The sample analyzer of claim 19, wherein the second reversing assembly comprises an annular second flexible drive member, a guide wheel; the two ends of the second flexible transmission piece are wound on the guide wheel and the power output shaft, the connecting structure is connected with the second flexible transmission piece, the power output shaft drives the second flexible transmission piece to move in the rotating process, and the second flexible transmission piece drives the connecting structure to linearly move along the first direction in the moving process.

Description

Sample analyzer Cross Reference to Related Applications The present application is based on and claims priority from chinese patent application number 202411582011.5, application day 2024, 11/06, entitled "a sample analyzer", the entire contents of which are incorporated herein by reference. Technical Field The application relates to the technical field of in-vitro diagnosis, in particular to a sample analyzer. Background In the related art, some sample analyzers have strict pollution prevention standards, so that the structural design thereof adopts a partition layout. The sample area is one of areas with most frequent interaction between the instrument and the external environment, and needs to be kept in an open state during sample injection. However, this openness may cause problems in both aspects of the sample injection process, that is, on the one hand, the pressure difference between the inside of the sample analyzer and the external environment may fluctuate, which may interfere with the stability of the environmental conditions inside the instrument during the sample detection process, and on the other hand, the contaminated gas inside the instrument may leak to the external environment, causing an exposure risk to the operator of the instrument, or the contaminated gas in the external environment enters the inside of the instrument, affecting the accuracy of the sample detection. Disclosure of Invention Embodiments of the present application desirably provide a sample analyzer to reduce the occurrence of leakage of contaminated gas inside the instrument to the external environment and entry of contaminated gas in the external environment into the instrument. The embodiment of the application provides a sample analyzer, which comprises a shell component, a sample introduction mechanism, a reaction device, a detection device and a shielding seat, wherein the shell component comprises a shell, the shell component is provided with an opening, the sample introduction mechanism comprises a sample seat and one or more baffles, the sample seat is used for carrying a sample to be tested, the sample container is used for containing a sample to be tested, the reaction device is used for providing a reaction place for a mixed solution containing the sample to be tested and a reagent in the reaction container and forming a reaction liquid, the detection device is used for detecting the reaction liquid to obtain a detection result of the sample to be tested, when the sample seat enters the interior of the shell component from the exterior of the shell component through the opening or protrudes from the interior of the shell component to the exterior of the shell component through the opening, the one or more baffles open the opening, and when the sample seat is located at a sample to be sucked position in the interior of the shell component or the sample seat is located at a loading position of the shell component, the one or more baffles are used for shielding the opening, and the sample seat to be placed at the sample seat to be sucked to the sample seat to be sucked by the sample seat to be placed at the sample position. In some embodiments, the sample introduction mechanism includes an unloaded state in which the sample holder carries a sample container to be retrieved, extending from an interior of the housing assembly to an exterior of the housing assembly through the opening to transport the sample container to be retrieved from the interior of the housing assembly to a retrieval location external to the housing assembly, the one or more baffles shielding the opening when the sample holder is in the retrieval location external to the housing assembly. In some embodiments, the interior of the housing assembly has a sample compartment having a gas pressure that is less than the gas pressure of the exterior of the housing assembly. In some embodiments, the sample analyzer further comprises a sample dispensing component and a pipetting component arranged on the sample dispensing component, wherein the sample dispensing component is used for driving the pipetting component to move between different operation positions so as to suck or discharge a sample to be measured, the sample analyzer further comprises a pressure detection mechanism and a processor, the pressure detection mechanism is used for detecting the pressure in the pipetting component, and the processor is used for receiving a pressure signal output by the pressure detection mechanism and determining whether the pipetting component leaks according to the pressure signal. In some embodiments, the sample analyzer further comprises a sample dispensing component and a pipetting component arranged on the sample dispensing component, wherein the sample dispensing component is used for driving the pipetting component to move between different operation positions so as to suck or discharge a sample to be measured, and the sample analyzer further comprise