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CN-122003170-A - Pest control composition

CN122003170ACN 122003170 ACN122003170 ACN 122003170ACN-122003170-A

Abstract

The present invention relates to a pest control composition comprising any one or more of phenol (e.g., thymol), aldehyde (e.g., vanillin), free fatty acids, fatty acid salts and lipopeptides, and a carrier and/or solvent. The present invention further relates to a pest control composition comprising thymol, an oil selected from the group consisting of rapeseed oil, soybean oil and diesel oil, a stabilizer and a solvent. The invention further relates to methods of preparing these pest control compositions and to the use of these compositions.

Inventors

  • S. YOUNIS
  • D. Avad
  • E. Kasab

Assignees

  • 地球母亲皮肤护理有限责任公司

Dates

Publication Date
20260508
Application Date
20241004
Priority Date
20231006

Claims (16)

  1. 1. A pest control composition comprising: a) Phenol (P), B) Aldehyde (A), C) Any one or more of free fatty acid (F), fatty acid salt (FS) and lipopeptide (L), and D) A carrier and/or a solvent.
  2. 2. The pest control composition of claim 1, wherein the phenol (P) is selected from the group consisting of thymol, thymol acetate, thymol dichloroacetate, thymol trichloroacetate, thymol diethyl ether, thymol propionate, thymol benzoate, and thymol glucoside.
  3. 3. The pest control composition according to claim 1 or 2, wherein the aldehyde (a) is selected from the group consisting of vanillin, vanillin acetate, o-vanillin, isovanillin, and 2-hydroxy-4-methoxybenzaldehyde.
  4. 4. A pest control composition according to any one of claims 1 to 3, wherein The free fatty acids (F) are selected from the group consisting of saturated and unsaturated C8-C20 fatty acids, in particular from the group consisting of octanoic acid, nonanoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid and eicosanoic acid, and/or The fatty acid salts (FS) are selected from the group consisting of potassium and sodium salts of saturated and unsaturated C8-C20 fatty acids, in particular from the group consisting of potassium salts of saturated and unsaturated C8-C18 fatty acids.
  5. 5. The pest control composition according to any one of claims 1 to 4, wherein the lipopeptide (L) is selected from the group consisting of a non-ribosomal lipopeptide, a synthetic lipopeptide, a hybrid thereof, and a combination thereof, The non-ribosomal lipopeptide is preferably selected from the group consisting of Bacillus thuringiensis (Bt) lipopeptides, surfactants, cyclomarin and isopentenyl diketopiperazine, and The ribosomal lipopeptides are preferably selected from the group consisting of lipolantibiotics, goadvionins, albopeptin, selidamides and cyanobacteria.
  6. 6. The pest control composition according to any one of claims 1 to 5, wherein the carrier and/or solvent is selected from one or more of the group consisting of oil, glycol and alcohol, The oil is preferably selected from the group consisting of petroleum, diesel, biodiesel, waste oil, waste edible oil, vegetable oil, polyunsaturated vegetable oil, olive oil, canola oil, sunflower seed oil, rapeseed oil, sesame oil, palm oil, soybean oil, castor oil, sulfonated castor oil, peanut oil, avocado oil, polyglycerol, safflower oil, sunflower oil, cinnamon oil, jojoba oil, seed oil, citronella oil, coconut oil, neem oil, thyme oil, lavender oil, eucalyptus oil, orange oil, peppermint oil, rosemary oil, basil oil, lemon oil, geranium oil, clove oil, patchouli oil, catmint oil, fennel oil, sage oil, rosewood oil, cedar wood oil, microbial oil, bacterial oil, yeast oil and algae oil; The diol is preferably an alkane diol, more preferably selected from the group consisting of 1, 3-propanediol, 1, 4-butanediol, 1, 5-pentanediol, 1, 6-hexanediol, 1, 8-octanediol, methylpropanediol and isopentanediol, and The alcohol is preferably selected from the group consisting of ethanol, isopropanol, butanol, methanol and hexanol.
  7. 7. The pest control composition according to any one of claims 1 to 6, wherein, The concentration of phenol (P) is about 2 to 40% (w/w), preferably about 5 to 20% (w/w), The concentration of aldehyde (A) is about 5-40% (w/w), preferably about 10-30% (w/w), If fatty acid (F) is present, its concentration is about 0.1 to 80% (w/w), preferably about 2 to 40% (w/w), If a fatty acid salt (FS) is present, its concentration is about 2-80% (w/w), preferably about 5-40% (w/w), If lipopeptides (L) are present, their concentration is about 0.1-10% (w/w), preferably about 1-5% (w/w), and/or The concentration of carrier and/or solvent is about 5-90% (w/w).
  8. 8. A method of preparing the pest control composition of any one of claims 1 to 7, wherein the components are mixed together A) Phenol (P), B) Aldehyde (A), and C) Any one or more of free fatty acid (F), fatty acid salt (FS) and lipopeptide (L) Mix and dissolve or dilute in d) carrier and/or solvent.
  9. 9. A pest control composition comprising thymol, an oil selected from the group consisting of rapeseed oil, soybean oil, and diesel, a stabilizer, and a solvent.
  10. 10. The pest control composition according to claim 9, wherein the stabilizer is selected from the group consisting of vanillin, alginate, agar, carrageenan, cellulose derivatives, gelatin, guar gum, gum arabic, locust bean gum, pectin, starch, xanthan gum, coconut oil, PPG-20 methyl glucose ether and acetyl hexamethylindane, in particular vanillin.
  11. 11. The pest control composition of claim 9 or 10, wherein the solvent is selected from the group consisting of alpha-omega alkyl glycol, jojoba oil, sulfonated castor oil, ethanol, isopropanol, hexadecane, propylene glycol n-butyl ether, propylene glycol methyl ether acetate, propylene glycol methyl ether, dipropylene glycol n-propyl ether, ethylene glycol methyl ether, and hexylene glycol.
  12. 12. The pest control composition according to any one of claims 9 to 11, wherein, Thymol concentration of about 2-60% (w/w), preferably about 10-40% (w/w), more preferably about 15-20% (w/w), The concentration of the oil is about 10-60% (w/w), preferably about 20-50% (w/w), more preferably about 30-40% (w/w), The concentration of stabilizer is about 10-60% (w/w), preferably about 15-40% (w/w), more preferably about 20-30% (w/w), and/or The concentration of the solvent is about 20-60% (w/w), preferably about 30-50% (w/w), more preferably about 35-45% (w/w).
  13. 13. A method of preparing a composition comprising thymol, an oil selected from the group consisting of rapeseed oil, soybean oil, and diesel, a stabilizer, and a solvent, the method comprising: Mixing said thymol, said oil, said stabilizer and said solvent, and Dissolving the thymol, the oil and the stabilizer in the solvent by incubating the mixture at a temperature and for a period of time sufficient to dissolve the thymol, the oil and the stabilizer in the solvent.
  14. 14. A composition prepared by the method of claim 8 or 13.
  15. 15. The pest control composition of any one of claims 1 to 7 or 9 to 12, wherein the pest belongs to the group consisting of: Arthropods, including the classes insect and arachnids, Bacteria, fungi and viruses, and Birds.
  16. 16. Use of the pest control composition according to any one of claims 1 to 7, 9 to 12 or 15 or the composition according to claim 14 for increasing milk and/or meat yield of livestock or for increasing agricultural yield.

Description

Pest control composition Technical Field The present invention relates to pest control compositions comprising, inter alia, (i.a.) a phenol (e.g., thymol) and an aldehyde (e.g., vanillin). The invention further relates to a process for preparing the above-described composition as well as to compositions prepared by such a process or compositions preparable by such a process. The invention further relates to the use of the above composition. The pest control composition of the present invention can be safely applied to animals (including livestock and humans) or agricultural products. Background Insect bites are not simply the inconvenience of causing irritation and pain, but can also constitute a serious health risk. The ability of insects and other pests to transmit bacteria, viruses and other vectors is well documented. For example, mosquitoes may transmit pathogens and viral particles into the blood stream when sucking the blood of a human host. Conditions such as malaria, yellow fever, lyme disease (LYME DISEASE) and dengue fever (Dengue fever) are due to mosquito bites. Each year, these diseases cause thousands of deaths worldwide. Aedes aegypti (AEDES AEGYPTI), also known as yellow fever mosquitoes as it is a vector for yellow fever viruses, is mainly found in tropical and subtropical regions around the world. However, recent studies have shown that they exist in continental areas such as germany and france. Aedes aegypti is diurnal and human-philic. It is also a vector for dengue and Zika virus. To date, there is no universally available immunization against this species. Topical mosquito repellents effective against this species ensure protection against viral transmission. It is also well known that ticks are the carrier responsible for the transmission of lyme disease and that fleas can transmit plague to humans. Synthetic compounds such as N, N-diethyl-m-toluamide (DEET) have been used as insect repellents for many years. DEET is considered an industry standard for topical insect repellents and is highly effective for a long period of time. However, in some cases, it may cause irritation of the skin, eyes and mucous membranes. In north america, insect repellents containing DEET have been under regulatory reevaluation. Such re-evaluation results in label changes and dose recommendations to minimize unnecessary exposure to sensitive populations (e.g., young children and pregnant women or lactating women). Other pest repellant compounds include 1- (1-methylpropoxycarbonyl) -2- (2-hydroxyethyl) piperidine (alternatively known as ecarin (icaridin), pecabain (picaridin) and KBR 3032) and ethyl 3- [ N-butyl-N-acetyl ] -aminopropionate (alternatively known as EBAAP, ethyl butylacetylaminopropionate (ethyl butylacetylaminopropionate) and insect repellant 3535), which raise similar concerns. Natural essential oils such as citronella, eucalyptus, lavender and limonene have also been used as insect repellents. Their repellency is generally initially strong, but due to their high volatility, these repellents lack long-term efficacy and the protection time is only in the range of 30 minutes to 2 hours. Furthermore, unrefined essential oils contain a blend of compounds, some of which, although present in minor concentrations, can pose health risks to sensitive populations (e.g., infants, pregnant women, and lactating women). These compounds are considered allergens, and therefore doctors recommend that infants as well as pregnant or lactating women avoid the use of natural essential oils. In addition, synthetic pesticides (pesticide) and insecticides (insecticide), such as organophosphates (organophosphates), pyrethroids (pyrethroids), carbamates (carbamates) and neonicotinoids (neonicotinoids), are widely used in agriculture and farming (i.e., for crops and livestock). In addition to health and environmental problems, the widespread use of synthetic pesticides and insecticides has also led to the rapid emergence of resistance in pest populations. All of these factors, except for the increasing regulatory restrictions on some pesticides, necessitate the provision of alternative solutions. Accordingly, there is a need for pest repellants that are effective for extended periods of time without posing health risks to animals, including livestock and humans. The object of the present invention is to address such a need. Object of the Invention In particular, it is an object of the present invention to provide a pest control composition, for example a pest control composition for topical application, which can be advantageously and safely applied to animals (including domestic animals and humans) or agricultural products. It is another object of the present invention to provide a safe pest control composition that can be applied to animals or agricultural products in large amounts. It is a further object of the present invention to provide a pest control composition that can be safely and continuously applied and re