CN-122003225-A - Compositions and methods of use thereof

Abstract

Provided herein is a composition comprising (i) at least one collagen, (ii) palmitoyl tripeptide-1, (iii) palmitoyl tetrapeptide-7, and (iv) palmitoyl tetrapeptide-10. Also provided herein is a non-therapeutic method for treating keratin materials, comprising applying the composition to keratin materials.

Inventors

• MA YUAN
• LI NINGZI
• ZANG SHANSHAN

Assignees

• 莱雅公司

Dates

Publication Date

20260508

Application Date

20231013

Claims (14)

1. 1. A composition comprising: (i) At least one collagen; (ii) Palmitoyl tripeptide-1; (iii) Palmitoyl tetrapeptide-7, and (Iv) Palmitoyl tetrapeptide-10.
2. 2. Composition according to claim 1, wherein the collagen is selected from type I collagen, type III collagen or type V collagen, preferably the collagen is water-soluble.
3. 3. The composition according to claim 1 or 2, wherein the collagen is present in an amount ranging from 0.005 ppm to 1000 ppm, preferably from 0.01 ppm to 500 ppm, more preferably from 0.05 ppm to 100 ppm, most preferably from 0.05 ppm to 4 ppm dry matter, relative to the total weight of the composition.
4. 4. A composition according to any one of claims 1-3, wherein palmitoyl tripeptide-1 is present in an amount ranging from 0.0002 ppm to 200 ppm, preferably from 0.001 ppm to 100 ppm, more preferably from 0.005 ppm to 50 ppm, most preferably from 0.01 ppm to 1 ppm, relative to the total weight of the composition.
5. 5. The composition according to any one of claims 1-4, wherein palmitoyl tetrapeptide-7 is present in an amount ranging from 0.0001 ppm to 100 ppm, preferably from 0.0005 ppm to 50 ppm, more preferably from 0.001 ppm to 25 ppm, most preferably from 0.005 ppm to 0.5 ppm, relative to the total weight of the composition.
6. 6. The composition according to any one of claims 1-5, wherein palmitoyl tetrapeptide-10 is present in an amount ranging from 0.0001 ppm to 10 ppm, preferably from 0.0005 ppm to 5 ppm, more preferably from 0.001 ppm to 1 ppm, most preferably from 0.002 ppm to 0.02 ppm, relative to the total weight of the composition.
7. 7. The composition of any one of claims 1-6, further comprising acetyl hexapeptide-8.
8. 8. The composition according to claim 7, wherein acetyl hexapeptide-8 is present in an amount ranging from 0.001 ppm to 30 ppm, preferably from 0.005 ppm to 10 ppm, more preferably from 0.01 ppm to 5 ppm, relative to the total weight of the composition.
9. 9. The composition of any one of claims 1-8, further comprising an aqueous phase.
10. 10. The composition of claim 9, wherein the aqueous phase comprises water.
11. 11. The composition according to claim 10, wherein water is present in an amount ranging from 50 to 99.99 wt%, preferably from 70 to 99.99 wt%, more preferably from 80 to 99.6 wt%, relative to the total weight of the composition.
12. 12. The composition of claim 1, comprising, relative to the total weight of the composition: (i) 0.05 ppm to 100 ppm of at least one collagen selected from the group consisting of type I collagen, type III collagen and type V collagen; (ii) 0.005 ppm to 50 ppm of palmitoyl tripeptide-1; (iii) 0.001 ppm to 25 ppm of palmitoyl tetrapeptide-7; (iv) 0.001 ppm to 1 ppm, and (V) Optionally 0.01 ppm to 5 ppm.
13. 13. A non-therapeutic method for caring for keratin materials, comprising applying to the keratin materials a composition according to any one of claims 1 to 12.
14. 14. Use of a composition according to any one of claims 1 to 12 for providing an anti-ageing effect on keratin materials.

Description

Compositions and methods of use thereof Technical Field The present invention relates to a composition. In particular, the present invention relates to a composition for caring for keratin materials. The invention also relates to a non-therapeutic method for caring for keratin materials. Background Human skin is composed of three compartments, namely the superficial compartment (which is the epidermis), the dermis and the deep compartment (which is the subcutaneous tissue). The dermis is composed mainly of fibroblasts and extracellular matrix (ECM). Such extracellular matrices are composed of various macromolecules responsible for the mechanical strength of the skin, its flexibility, its tonicity and its elasticity, and also for physiologically important functions (hydration, thermoregulation and regulation of skin permeability). These macromolecules include, in particular, collagen, elastin and glycocomplexes (glycoproteins and proteoglycans). Collagen accounts for 70% of the proteins of ECM. Of course, collagen is continually updated, but this update decreases with age, which results in thinning of the dermis. A wide variety of cosmetics have been used to care for the skin, for example to counteract skin ageing by promoting collagen production. However, some cosmetics on the market are not satisfactory in resisting skin aging. Thus, there remains a need to formulate compositions for treating skin that are effective against skin aging. Summary of The Invention The object of the present invention is thus to develop a composition for caring skin which is effective against skin ageing. It is another object of the present invention to provide a cosmetic method for caring for the skin. The inventors have now found that the compositions of the present invention are effective against skin ageing. Accordingly, in a first aspect, the present invention provides a composition comprising: (i) At least one collagen; (ii) Palmitoyl tripeptide-1; (iii) Palmitoyl tetrapeptide-7, and (Iv) Palmitoyl tetrapeptide-10. The inventors have found that the composition of the present invention can be effective against skin aging by promoting the production of type III collagen and type IV collagen. In a second aspect, the present invention provides a non-therapeutic method for treating keratin materials, comprising applying to the keratin materials a composition according to the first aspect of the invention. In a third aspect, the present invention provides the use of a composition according to the first aspect of the invention for providing an anti-ageing effect on a keratin material. Other subjects and features, aspects and advantages of the present invention will become even more apparent from a reading of the following description and examples. Detailed Description Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The definitions set forth herein should be applicable when the definitions of terms in this specification conflict with the meaning commonly understood by those skilled in the art to which this invention pertains. Hereinafter, and unless otherwise indicated, the limits of the numerical ranges are included in this range, in particular in the expression "between the term" and "is used herein. The" and "ranges are in the" to "ranges. Furthermore, the expression "at least one" as used in the present specification is equivalent to the expression "one or more". Throughout this disclosure, the term "comprising" should be interpreted to cover all the specifically mentioned features as well as optional, additional, unspecified features. As used herein, use of the term "comprising" also discloses embodiments in which no feature other than the specifically mentioned feature is present (i.e. "consisting of). Unless otherwise indicated, all numbers expressing quantities of ingredients and so forth used in the specification and claims are to be understood as being modified by the term "about". Accordingly, unless indicated to the contrary, the numerical values and parameters set forth herein are approximations that can vary depending upon the desired purposes. For the purposes of the present invention, the term "keratin materials" is intended to cover the skin, mucous membranes of the human body, such as the lips. Facial skin is most particularly contemplated in accordance with the present invention. All percentages in this invention refer to weight percentages unless otherwise indicated. According to a first aspect, the composition of the invention comprises: (i) At least one collagen; (ii) Palmitoyl tripeptide-1; (iii) Palmitoyl tetrapeptide-7, and (Iv) Palmitoyl tetrapeptide-10. Collagen protein According to a first aspect, the composition of the invention comprises at least one collagen. For the purposes of the present invention, collagen may be any type of collagen from any source. In this r