Search

CN-122004460-A - Anti-hypoxia composition containing saussurea involucrata culture and preparation method thereof

CN122004460ACN 122004460 ACN122004460 ACN 122004460ACN-122004460-A

Abstract

The invention discloses an anti-hypoxia composition containing saussurea involucrata culture and a preparation method thereof, belongs to the technical field of food, and relates to functional food. An anti-hypoxia composition containing saussurea involucrata culture comprises, by weight, 150-250 parts of saussurea involucrata culture, 0-25 parts of a magnesium element reagent, 0-1.5 parts of a zinc element reagent, 0-4 parts of an iron element reagent, 400-500 parts of isomalt, 2-6 parts of hydroxypropyl methyl cellulose, 0.1-2 parts of sucralose, 0.1-2 parts of sodium carboxymethyl cellulose, 2-6 parts of magnesium stearate and 4-10 parts of food-grade coating powder. The composition disclosed by the invention not only can help to improve altitude stress symptoms and reduce adverse effects of hypoxia on heart and lung tissues, but also has the advantages of safety, portability, stability and compliance, and is suitable for various people exposed to altitude environments.

Inventors

  • ZHOU MANXIANG
  • GAO ZHONGGAO
  • WANG SHUANGQING
  • ZHAO JINYU
  • Jia Kangjie
  • WU FUGUAN
  • LU XUE

Assignees

  • 山西康宝生物科技有限公司

Dates

Publication Date
20260512
Application Date
20260312

Claims (10)

  1. 1. An anti-hypoxia composition containing a saussurea involucrata culture, which is characterized by comprising the following components in parts by weight: 150-250 parts of saussurea involucrata culture, 0-25 parts of magnesium element reagent, 0-1.5 parts of zinc element reagent, 0-4 Parts of iron element reagent, 400-500 parts of isomaltulose alcohol, 2-6 parts of hydroxypropyl methyl cellulose, 0.1 To 2 parts of sucralose, 0.1 to 2 parts of sodium carboxymethylcellulose, 2 to 6 parts of magnesium stearate, 4-10 Parts of food-grade coating powder.
  2. 2. The anti-hypoxia composition of claim 1, wherein the anti-hypoxia composition of the culture comprises the following components in parts by weight: 175-220 parts of saussurea involucrata culture, 15-25 parts of magnesium element reagent, 0.2-1.5 parts of zinc element reagent, 1-4 Parts of iron element reagent.
  3. 3. The anti-hypoxia composition of claim 1, wherein the anti-hypoxia composition of the culture comprises the following components in parts by weight: 175-200 parts of saussurea involucrata culture, 17-22 parts of magnesium element reagent, 0.5-1 part of zinc element reagent, 1.5-3 Parts of iron element reagent.
  4. 4. The anti-hypoxia composition of claim 1, wherein the elemental magnesium agent is one or more of magnesium citrate, magnesium gluconate, magnesium L-threonate, magnesium ascorbyl phosphate, magnesium sulfate, magnesium chloride, magnesium oxide, magnesium carbonate, magnesium hydrogen phosphate.
  5. 5. The anti-hypoxia composition of claim 1, wherein the elemental zinc agent is one or more of zinc sulfate, zinc gluconate, zinc glycinate, zinc oxide, zinc lactate, zinc citrate, zinc chloride, zinc acetate, zinc carbonate, zinc carnosine, zinc picolinate, and zinc-rich yeast.
  6. 6. The anti-hypoxia composition of claim 1, wherein the elemental iron agent is one or more of ferrous sulfate, ferrous gluconate, ferric ammonium citrate, ferrous fumarate, ferric citrate, ferrous lactate, methemoglobin chloride, ferric pyrophosphate, ferriporphyrin, ferrous glycinate, reduced iron, sodium ferric ethylenediamine tetraacetate, carbonyl iron powder, ferrous carbonate, ferrous citrate, ferrous fumarate, ferrous succinate, ferric heme, and electrolytic iron.
  7. 7. The anti-hypoxia composition of claim 1, wherein the food grade coating powder is one or more of hydroxypropyl methylcellulose, povidone, talc, and polyethylene glycol.
  8. 8. The method for preparing the anti-hypoxia composition containing the saussurea involucrata culture of claim 1, wherein the preparation process comprises the following steps: (1) Pretreating, namely crushing the saussurea involucrata culture to be more than or equal to 100 meshes; (2) Mixing and granulating: firstly, mixing a zinc element reagent and an equivalent isomaltulose alcohol to obtain mixed powder A; mixing the mixed powder A with equivalent isomaltulose alcohol to obtain mixed powder B; mixing the mixed powder B with an iron element reagent to obtain mixed powder C; mixing the mixed powder C with equivalent isomaltulose alcohol to obtain mixed powder D; Sequentially adding the crushed saussurea involucrata culture, hydroxypropyl methylcellulose, mixed powder D, a magnesium element reagent, sucralose and the rest isomaltulose alcohol into a mixing granulator, and stirring for 15-20 minutes to obtain a mixed material; Then preparing sodium carboxymethyl cellulose into an aqueous solution with the mass concentration of 1% -2% as an adhesive, adding the aqueous solution into the mixed material, and granulating to obtain wet granules; (3) Drying, namely spreading the wet particles in a boiling dryer for drying to obtain particles; (4) And (3) mixing, namely adding the particles and magnesium stearate into a mixer, uniformly mixing, tabletting and coating to obtain the finished product.
  9. 9. The method for preparing the anti-hypoxia composition containing the saussurea involucrata culture according to claim 8, wherein the stirring paddle of the mixer-granulator has a rotating speed of 15-25 HZ, a fly cutter has a rotating speed of 40-50 HZ and stirring time of 15-20 minutes.
  10. 10. The preparation method of the hypoxia resistant composition containing the saussurea involucrata culture according to claim 8, wherein the motor frequency of the dryer is 30-40 HZ, the air inlet temperature is 50-70 ℃, the air outlet temperature is 45-50 ℃, and the temperature is dried until the moisture content of particles is 2% -4%.

Description

Anti-hypoxia composition containing saussurea involucrata culture and preparation method thereof Technical Field The invention belongs to the technical field of foods, relates to functional foods, and in particular relates to an anti-hypoxia composition containing a saussurea involucrata culture and a preparation method thereof. Background With the increasing number of plateau tourism, plateau region construction and scientific investigation activities, the influence of the plateau environment on human health is increasingly concerned. The plateau area has special geographical and climatic characteristics of low pressure, hypoxia, large day and night temperature difference, strong ultraviolet rays and the like, wherein the low pressure hypoxia is a core cause for causing the human body to generate altitude reaction. The altitude reaction is also called altitude sickness and mountain sickness, is a series of physiological dysfunction symptoms caused by the lack of adaptability of a human body to an anoxic environment after the human body enters the altitude environment with the altitude of more than 3000 meters, is commonly manifested by dizziness, headache, shortness of breath, hypodynamia, nausea, vomit, sleep disorder and the like, and can also induce critical diseases such as altitude pulmonary edema, cerebral edema and the like when serious, thereby not only affecting the travel experience of altitude travelers, but also forming a potential threat to the physical health and the working efficiency of groups such as long-term altitude workers, frontier and the like. At present, the coping modes aiming at altitude reaction mainly comprise three types of advanced adaptation, physical protection and taking auxiliary products. The method has the advantages that the method is long in adaptation period in advance, the requirements of short-term altitude travel people are difficult to meet, physical protection (such as oxygen inhalation) is limited by equipment, portability is poor, continuous protection cannot be realized, most of the existing auxiliary products are medicinal preparations or single-component foods, side effects can exist in the medicinal preparations, and the single-component products have single action mechanism, so that the altitude reaction symptoms are difficult to fully relieve and the organism tissues are difficult to protect. Therefore, developing a safe, portable, and fully functional, plateau-environment-adapting food composition is an urgent need in the current industry. Saussurea involucrata is used as a special rare medicinal plant on the plateau and is rich in nutrient components such as flavonoid compounds, polysaccharide, alkaloid and the like. However, natural saussurea involucrata belongs to a national second-level protection wild plant, is forbidden to be illegally picked by legal protection, has scarce natural resources, and cannot meet the requirement of large-scale application. Patent CN 121058558A discloses a technical scheme for obtaining a saussurea involucrata culture by an artificial tissue culture technology, the types and the content of active ingredients are similar to those of natural saussurea involucrata, and the ingredients are rich in selenium and chromium, and have the advantages of legal source, controllable quality and mass production. In the prior art, although attempts are made to prepare health foods by combining medicinal plants with other nutrient substances, researches on special demands of organisms in a plateau environment are few, the effects of reducing adverse effects of hypoxia on heart and lung tissues are low, the stability of a preparation process is poor, and market blank is large. In order to solve the above problems in the prior art, an anti-hypoxia composition containing a saussurea involucrata culture and a preparation method thereof are developed. Disclosure of Invention The invention aims to provide an anti-hypoxia composition containing a saussurea involucrata culture. Another object of the invention is a method for preparing an anti-hypoxia composition by a culture comprising saussurea involucrata. In order to achieve the above purpose, the present invention discloses the following technical solutions: An anti-hypoxia composition containing a saussurea involucrata culture comprises the following components in parts by weight: 150-250 parts of saussurea involucrata culture, 0-25 parts of magnesium element reagent, 0-1.5 parts of zinc element reagent, 0-4 Parts of iron element reagent, 400-500 parts of isomaltulose alcohol, 2-6 parts of hydroxypropyl methyl cellulose, 0.1 To 2 parts of sucralose, 0.1 to 2 parts of sodium carboxymethylcellulose, 2 to 6 parts of magnesium stearate, 4-10 Parts of food-grade coating powder. Further, the anti-hypoxia composition containing the saussurea involucrata culture comprises the following components in parts by weight: 175-220 parts of saussurea involucrata culture, 15-25 parts of magnesium element r