CN-122004871-A - Bioelectric interface system with interface function partition and application thereof

Abstract

The invention discloses a bioelectric interface system with interface function partition and application thereof, the system constructs a target tissue signal coupling area and a non-target tissue interference suppression area in a flexible bioelectric interface, the functional partitioning of interface contact behavior is realized, and mechanical disturbance and electric noise interference caused by simultaneous contact of multiple groups are reduced from the system level, so that the stability and fidelity of bioelectric signal acquisition are improved. The bioelectric interface system comprises a flexible interface layer, a stretchable conductive path and a packaging structure, wherein the target tissue signal coupling region is used for forming a stable and low-impedance electric coupling interface with biological tissues, and the non-target tissue interference suppression region is used for reducing the influence of excessive interface contact and multi-source mechanical coupling on signal acquisition.

Inventors

• LI FENGYU
• HE ZILONG
• LIN HAOWEN
• WU SHAOXIONG

Assignees

• 暨南大学
• 广东比派科技有限公司

Dates

Publication Date

20260512

Application Date

20260121

Claims (3)

1. 1. A bioelectric interface system with partitioned interface functions, wherein the bioelectric interface system preparation method comprises the following steps: Mixing liquid metal with a high polymer stabilizer, performing probe ultrasonic treatment under a water bath condition to obtain conductive ink with good dispersibility, adopting a direct-writing printing mode to pattern and deposit the conductive ink on the surface of a flexible Polyurethane (PU) film, and after the solvent volatilizes, forming a continuous conductive network inside the conductive path through mechanical treatment to obtain a stretchable and bendable flexible conductive path; Attaching or covering the conductive path obtained in the first step with a flexible packaging layer to enable the conductive path to be packaged in the flexible structure, and improving the mechanical stability and the electrical stability of the conductive path in stretching, bending and wetting environments; Constructing a flexible interface layer at one side of the conductive path, and forming at least two interface areas with different functions in the interface layer, wherein the interface areas comprise a target tissue signal coupling area and a non-target tissue interference suppression area, the target tissue signal coupling area is used for forming a stable and low-impedance electrode-tissue coupling interface with target biological tissues, and the non-target tissue interference suppression area is used for reducing the influence of adhesion, friction and mechanical disturbance generated in the contact process of the non-target tissues on signal acquisition; And step four, integrating the structure constructed in the step two and the step three integrally to form an integrated bioelectric interface system by the flexible interface layer, the conductive path and the packaging structure, thereby realizing the functions of acquiring, transmitting and stabilizing the interface of bioelectric signals.
2. 2. The bioelectric interface system of claim 1, wherein in the first step, the liquid metal is gallium-based or gallium-indium alloy, the molar ratio of gallium to indium is 1:1-1:5, and the ultrasonic power is 200-800W.
3. 3. The bioelectric interface system of claim 1, wherein the interface function partition is realized by interface layer composition differences, interface configuration differences or interface contact mode differences, instead of relying on uniform changes in the overall properties of a single interface material.

Description

Bioelectric interface system with interface function partition and application thereof Technical Field The invention relates to the technical field of bioelectronics and flexible electronic devices, in particular to a bioelectric interface system with an interface function partition and application thereof. Background Bioelectric signals (such as myoelectricity, electrocardio and the like) are important information carriers for reflecting the electric activity state of biological tissues, and have wide application value in the fields of sports health monitoring, rehabilitation evaluation, clinical auxiliary diagnosis and the like. The bioelectric interface is used as a key bridge between biological tissues and a signal acquisition circuit, and the performance of the bioelectric interface directly determines the stability, the signal-to-noise ratio and the long-term monitoring reliability in the signal acquisition process. In the prior art, surface electrode systems typically rely on a metal electrode to form a tissue-electrode coupling interface with a conductive gel or flexible interface layer (e.g., US 3998215A). However, there is a significant mechanical mismatch between the conventional rigid electrode and soft, physiologically dynamic tissue, which is prone to contact state fluctuations in the motion or body fluid environment, thereby causing motion artifacts, baseline drift, and signal attenuation (e.g., KR20140144173 a). In order to improve interface adhesion, flexible interface materials such as hydrogel are introduced in the prior art for acquiring bioelectric signals, but the schemes mostly take the overall uniform interface characteristic as a design premise, and when the interface contacts target tissues and surrounding non-target tissues at the same time, external disturbance still enters a signal acquisition area through interface coupling, so that signal stability is affected (as in US20140206976A 1). Aiming at the problems that a gel interface is easy to absorb water and expand and the adhesion performance is attenuated in a wet environment, the prior patent proposes to obtain differential adhesion behaviors through asymmetric interface regulation of a material layer, for example, an asymmetric adhesion hydrogel prepared through a reverse regulation strategy is disclosed, and the asymmetric adhesion hydrogel is applied to surface electromyographic signal acquisition. The technology takes a preparation method of a hydrogel material and interface chemical regulation as a core, and improves the moisture resistance and the adhesion stability (such as CN 118599052A) by regulating the surface compositions of two sides of the gel. However, the above prior art is mainly focused on improvement of the interface material body or its preparation process, and its technical starting point is still focused on "obtaining an asymmetric gel material with better properties". In practice, the bioelectric interface is often not composed of only a single interface material, but rather a multi-layered system structure including conductive vias, encapsulation layers, flexible support structures, and tissue contact interfaces. In the system, different interface areas bear different functions on mechanical response, wetting behavior and signal coupling paths, only depend on asymmetric design of a material body, and the problem that stable coupling of target tissue signals and interference suppression of non-target tissues coexist is difficult to solve from a system level. In addition, under dynamic motion conditions, traction, friction and body fluid disturbance generated by non-target tissues are often transmitted to a signal acquisition area through an interface integral structure, so that non-negligible background noise is formed. The existing technical scheme taking material preparation as a core does not systematically design the cooperative relationship of all functional interfaces in the bioelectric interface, and directional regulation and control of a signal transmission path and effective isolation of an interference source are difficult to realize. Therefore, the thinking of optimizing the interface performance purely from the material preparation angle is necessary to be jumped out, and a bioelectric interface scheme capable of realizing stable coupling of target tissue signals, disturbance suppression of non-target interfaces and high-fidelity transmission of electric signals in the same interface is constructed from the aspect of the bioelectric interface system structure and interface function partition design so as to meet the actual requirements of long-term and stable acquisition of bioelectric signals in a complex physiological environment. The information disclosed in this background section is only for enhancement of understanding of the general background of the invention and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already kno