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CN-122004976-A - Elastic implant for reducing lung volume and lung volume reduction container

CN122004976ACN 122004976 ACN122004976 ACN 122004976ACN-122004976-A

Abstract

The invention discloses a lung volume-reducing elastic implant and a lung volume-reducing instrument, which comprise a coiled elastic deformation section, a flexible guide section positioned at the far end of the implant, a flexible connecting section positioned at the near end of the implant, a far-end straight section and a near-end straight section, wherein the far-end straight section is arranged between the flexible guide section and the elastic deformation section, the far-end straight section extends straight along the tail end of the elastic deformation section connected with the flexible guide section, the near-end straight section extends straight along the tail end of the elastic deformation section connected with the flexible straight section, the deflection force required by the deflection of the flexible guide section relative to the far-end straight section is smaller than the deflection force required by the deflection of the flexible connecting section relative to the near-end straight section, and the deflection force required by the deflection of the flexible connecting section relative to the near-end straight section is smaller than the deflection force required by the deflection of the near-end straight section relative to the elastic deformation section. The invention aims to solve the technical problem that the existing implant is easy to shift after implantation.

Inventors

  • LI ANNING
  • ZHENG YUQIAN
  • Jia Zhenzhu

Assignees

  • 深圳市先健呼吸科技有限公司

Dates

Publication Date
20260512
Application Date
20241112

Claims (15)

  1. 1. A lung volume-reducing elastic implant body, which has shape memory property, at least partially takes a winding shape under the natural state, can be restrained to be long-strip shape under the action of preset external force and can be restored to the natural state after the external force is removed, and comprises an elastic deformation section taking the winding shape, a flexible guide section positioned at the far end of the implant body and a flexible connecting section positioned at the near end of the implant body, and is characterized in that the implant body also comprises a far-end straight section and a near-end straight section; The distal straight section is arranged between the flexible guide section and the elastic deformation section, the distal end of the distal straight section is connected with the proximal end of the flexible guide section, the proximal end of the distal straight section is connected with the distal end of the elastic deformation section, and the distal straight section extends straight along the tail end of the elastic deformation section connected with the distal straight section; the proximal straight section is arranged between the flexible connecting section and the elastic deformation section, the proximal end of the proximal straight section is connected with the distal end of the flexible connecting section, the distal end of the proximal straight section is connected with the proximal end of the elastic deformation section, the proximal straight section extends straight along the tail end of the elastic deformation section connected with the proximal straight section, The deflection force required by the deflection of the flexible guide section relative to the distal straight section is smaller than the deflection force required by the deflection of the distal straight section relative to the elastic deformation section; the deflection force required by the deflection of the flexible connection section relative to the proximal straight section is less than the deflection force required by the deflection of the proximal straight section relative to the elastically deformable section.
  2. 2. The lung volume reducing elastic implant of claim 1, wherein the elastically deformable section comprises 35% -80% of the total implant length, and the distal straight section and the proximal straight section each comprise 3% -20% of the total implant length.
  3. 3. The elastic lung volume reduction implant according to claim 1, wherein the elastically deformable section in a coil shape comprises a plurality of substantially C-shaped bent sections, the plurality of bent sections being connected in sequence, the connected bent sections being spirally wound at intervals between the distal straight section and the proximal straight section, free ends of the bent sections at both ends being connected to the distal straight section and the proximal straight section, respectively, wherein the bent section at one end faces the bent section at the other end after winding such that the distal straight section and the proximal straight section connected to the bent sections at both ends, respectively, have a tendency to approach each other with respect to the elastically deformable section.
  4. 4. The elastic implant according to claim 3, wherein the bending section is provided with an even number, the distal straight section and the proximal straight section are located on both sides of the elastic deformation section after the even number of bending sections are connected, the elastic deformation section is compressed in a spacing direction of the even number of bending sections, and an angle between projections of an extending direction of the distal straight section and an extending direction of the proximal straight section in a direction perpendicular to the compressing direction is not more than 180 °.
  5. 5. The elastic lung volume reduction implant of claim 4, wherein the elastically deformable section comprises at least a first curved section and a second curved section, a distal end of the first curved section being connected to a proximal end of the distal straight section, a proximal end of the second curved section being connected to a distal end of the proximal straight section, wherein the distal straight section is substantially coplanar with the first curved section connected thereto to form a first plane, the proximal straight section is substantially coplanar with the second curved section connected thereto to form a second plane, and an angle between the first plane and the second plane is between 40 ° and 90 °.
  6. 6. The lung volume reducing elastic implant according to claim 1, wherein the elastic deformation section has a bending resistance greater than the bending resistance of the flexible guiding section, the distal straight section has a bending resistance greater than or equal to the bending resistance of the elastic deformation section, and/or, The bending resistance of the elastic deformation section is larger than that of the flexible connection section, and the bending resistance of the proximal straight section is larger than or equal to that of the elastic deformation section.
  7. 7. The lung volume reducing elastic implant of claim 1, wherein the minimum bending radius of the elastically deformed segment is 12mm or less.
  8. 8. The elastic lung volume reduction implant according to any of claims 1-7, further comprising an anchor provided at least on the distal straight section of the implant, the anchor being adapted to contact tissue to prevent displacement of the implant relative to the tissue.
  9. 9. The lung volume reducing elastic implant according to claim 8, wherein said anchor comprises an anchor, wherein, The root of the anchor is connected with the far-end straight section, the free end of the anchor extends towards the proximal side of the implant, and the distance from the anchor to the far-end straight section is gradually increased from far to near; the root of the anchor is connected with the far-end straight section, the free end of the anchor extends towards the far-end side, and the distance between the anchor and the far-end straight section gradually increases from near to far, or, The root of the anchor is connected with the far-end straight section, and the free end of the anchor extends towards the far-end side for a preset distance and then rotates to extend towards the near-end side.
  10. 10. The elastic lung volume reduction implant according to claim 9, wherein the implant comprises a hollow tubular base body and an elastic membrane at least partially attached to the surface of the tubular base body, wherein a slit is provided in the distal flat section of the tubular base body, the anchor is provided in the position corresponding to the slit, and the free end of the anchor penetrates through the elastic membrane.
  11. 11. The elastic implant for reducing pulmonary volume according to claim 10, wherein the anchor is self-expandable and is deformable by an external force, a perforation is provided in the elastic membrane corresponding to the slot, and a free end of the anchor extends through the perforation and is placed in the slot through the perforation by the external force.
  12. 12. The lung volume reducing elastic implant according to claim 9, wherein said slit is provided on an inner side of said distal flat section of said tubular base body facing said elastically deforming section.
  13. 13. The elastic lung volume reducing implant of claim 8, wherein the implant comprises a hollow tubular base and an elastic membrane at least partially attached to a surface of the tubular base, wherein the anchor comprises an anchor structure formed on the elastic membrane of the distal straight section, wherein the anchor structure comprises one or more of a spiral structure, a convex structure, a concave structure.
  14. 14. The elastic lung volume reducing implant of claim 13, wherein said elastic membrane on said distal flat section comprises at least one non-contact section separate from said tubular base, said anchoring structure being provided on the membrane of said non-contact section.
  15. 15. A lung volume reduction device comprising an implant according to any one of claims 1 to 14 and a delivery means associated with the implant, the delivery means comprising a core wire and a hollow pushing member, the implant being detachably connected to the distal end of the pushing member by a proximal end of the implant, the core wire being removably threaded into the lumen of the implant and the lumen of the pushing member.

Description

Elastic implant for reducing lung volume and lung volume reduction container Technical Field The invention relates to the technical field of interventional medical instruments, in particular to a lung volume-reducing elastic implant and a lung volume-reducing instrument. Background Emphysema is a common chronic obstructive pulmonary disease with a high incidence especially in the elderly. It is counted that patients with end-stage emphysema have a survival rate of less than 50% for 5 years. Traditional treatment methods comprise oxygen inhalation, prevention of pulmonary infection, bronchospasmolysis and the like, but have limited curative effects. The surgical operation for treating the emphysema has the problems of severe surgical indication, more complications, high cost and the like, and part of patients cannot tolerate the operation due to poor lung function, so that the postoperative mortality rate is high. At present, a lung volume reduction implant is taken as a percutaneous interventional treatment means, enters the lung through a bronchoscope working channel, and is restored to be deformed to a natural shape after the restraint of a loading system is removed, an emphysema area is extruded, gas is discharged, and the lung tissue volume is reduced, so that the lung function is improved. Although existing lung volume reduction implants have shown some efficacy in clinical applications, during actual use, it is noted that existing implants are not designed to be adequate, particularly after implantation, and are subject to displacement. Such shifts not only affect the therapeutic effect, but may also pose additional complications risks to the patient, limiting the safety and effectiveness of their clinical application. Disclosure of Invention The invention provides an improved lung volume-reducing elastic implant and a lung volume-reducing instrument, and aims to solve the technical problem that the existing implant is easy to shift after implantation. In order to solve the above technical problems, the embodiments of the present invention provide the following technical solutions: The invention provides a lung volume-reducing elastic implant body, which has shape memory property, at least partially takes a winding shape in a natural state, can be restrained to be in a strip shape under the action of preset external force and can be restored to the natural state after the external force is removed, and comprises an elastic deformation section taking the winding shape, a flexible guide section positioned at the far end of the implant body and a flexible connecting section positioned at the near end of the implant body, and is characterized in that the implant body also comprises a far-end straight section and a near-end straight section; The distal straight section is arranged between the flexible guide section and the elastic deformation section, the distal end of the distal straight section is connected with the proximal end of the flexible guide section, the proximal end of the distal straight section is connected with the distal end of the elastic deformation section, and the distal straight section extends straight along the tail end of the elastic deformation section connected with the distal straight section; the proximal straight section is arranged between the flexible connecting section and the elastic deformation section, the proximal end of the proximal straight section is connected with the distal end of the flexible connecting section, the distal end of the proximal straight section is connected with the proximal end of the elastic deformation section, the proximal straight section extends straight along the tail end of the elastic deformation section connected with the proximal straight section, The deflection force required by the deflection of the flexible guide section relative to the distal straight section is smaller than the deflection force required by the deflection of the distal straight section relative to the elastic deformation section; the deflection force required by the deflection of the flexible connection section relative to the proximal straight section is less than the deflection force required by the deflection of the proximal straight section relative to the elastically deformable section. In one embodiment, the elastically deformable section comprises 35% -80% of the total length of the implant, and the distal straight section and the proximal straight section each comprise 3% -20% of the total length of the implant. In an embodiment, the coiled elastic deformation section comprises a plurality of approximately C-shaped bending sections, the bending sections are sequentially connected, the connected bending sections are spirally coiled at intervals between the distal straight section and the proximal straight section, the free ends of the bending sections at two ends are respectively connected with the distal straight section and the proximal straight section, the f