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CN-122005142-A - Beating device of spinal cord injury animal model and operation method

CN122005142ACN 122005142 ACN122005142 ACN 122005142ACN-122005142-A

Abstract

The invention provides a beating device of a spinal cord injury animal model, which belongs to the technical field of medicine, and is characterized in that a one-way mechanism is additionally arranged on a striker positioner connected with a striker, and an automatic restorer is arranged on the striker; when the device is used, the first positioning component in the striker positioner is connected with the striker, after the striker falls down to strike the experimental animal, the automatic restorer drives the striker to move upwards, meanwhile, the first positioning component connected with the striker is subjected to upward force, and the first positioning component rotates upwards along with the unidirectional mechanism, so that the unidirectional mechanism locks the first positioning component, the second positioning component is prevented from falling down, and the striker is prevented from striking the spinal cord of the experimental animal for the second time.

Inventors

  • WANG XIAOYU
  • ZHENG ZUNCHENG
  • SUN LIMIN
  • DU JIUBIN
  • CHEN HAOYUE

Assignees

  • 泰安市中心医院(青岛大学附属泰安市中心医院、泰山医养中心)

Dates

Publication Date
20260512
Application Date
20240415

Claims (10)

  1. 1. A striking device of a spinal cord injury animal model comprises a striker (4) and an animal model fixing table (7), and is characterized by further comprising: The firing pin positioner comprises a support frame (3), and a first positioning component (1) and a second positioning component (2) which are arranged on the support frame (3) up and down; The first positioning component (1) is arranged at the upper end of the firing pin (4) and is used for controlling the firing pin (4) to freely fall; The second positioning component (2) is arranged at the lower end of the firing pin (4) and is vertically arranged above the animal model fixing table (7) and used for adjusting the direction of the firing pin striking the spinal cord of the experimental animal; The automatic restorer (5) is arranged at the lower end of the firing pin (4), is connected with the second positioning component (2) and is used for driving the firing pin (4) to move upwards after the firing pin (4) falls down to strike the spinal cord of the animal; The one-way mechanism (6) is arranged between the first positioning component (1) and the supporting frame (3) and is used for fixing the first positioning component (1) when the striker (4) drives the first positioning component (1) to move upwards.
  2. 2. The beating device of the spinal cord injury animal model according to claim 1, wherein the unidirectional mechanism (6) comprises a unidirectional rotating rod (61) and a unidirectional clamping piece (62); one end of the unidirectional rotating rod (61) is connected with the first positioning component (1), and the other end of the unidirectional rotating rod is connected with the support frame (3) through the unidirectional clamping piece (62).
  3. 3. The beating device of the spinal cord injury animal model according to claim 2, wherein the striker (4) comprises a striker body (41), a rotary connector (42) and a connecting rod (43); One end of the connecting rod (43) is connected with the first positioning component (1), and the other end of the connecting rod is connected with the firing pin body (41) through the rotating connecting piece (42).
  4. 4. The beating device of the spinal cord injury animal model according to claim 2, wherein the positioning component II (2) comprises a double-layer cross slide bar (21), a transmission belt (22) and a lower limiting block (23): one end of the double-layer cross slide bar (21) is connected with the lower limiting block (23), and the other end of the double-layer cross slide bar is connected with the support frame (3); the transmission belt (22) is arranged on the double-layer cross slide bar (21) and is used for adjusting the position of the lower limiting block (23).
  5. 5. The beating device of the spinal cord injury animal model according to claim 4, wherein the double-layer cross slide bar (21) comprises a movable rod (21 a), a control rod (21 b) and two driving parts (21 c), wherein the movable rod (21 a) and the control rod (21 b) are mutually perpendicular and are arranged up and down through a sliding block (8); The movable rod (21 a) is connected with the lower limiting block (23); The two driving parts (21 c) are respectively arranged at two ends of the control rod (21 b) and are connected with the driving belt (22), and the position of the lower limiting block (23) is adjusted by controlling the driving direction of the driving belt (22).
  6. 6. The beating device of the spinal cord injury animal model according to claim 5, wherein the positioning assembly I (1) comprises a square slideway (11), and a transverse sliding rod (12) and a longitudinal sliding rod (13) which are arranged in the square slideway (11), wherein the transverse sliding rod (12) and the longitudinal sliding rod (13) are connected through an upper limiting block (14); the upper end of the firing pin (4) is arranged in the upper limiting block (14).
  7. 7. The beating device of the spinal cord injury animal model according to claim 6, wherein the lower side of the animal model fixing table (7) is also provided with an animal model limb fixing mechanism (9); The animal model limb fixing mechanism (9) comprises a binding belt (91), a stop block (92) and an automatic tightening assembly (93); The binding band (91) is connected with the automatic tightening assembly (93); One end of the automatic tightening component (93) is connected with the stop block (92), and the other end of the automatic tightening component is fixedly arranged at the lower end of the animal model fixing table (7).
  8. 8. The beating device of a spinal cord injury animal model according to claim 7, further comprising an automatic release mechanism (10) comprising a spring (101) and a release paddle (102); the release pulling piece (102) is arranged on one side of the animal model fixing table (7) close to the supporting frame (3); the spiral spring (101) is arranged on the bottom surface of the animal model fixing table (7) and is arranged with the same center line as the spiral spring (101).
  9. 9. The beating device of a spinal cord injury animal model according to claim 7, further comprising a release lever (103); the release rod (103) is arranged on one side of the supporting frame (3) and is fixedly connected with the firing pin (4).
  10. 10. A method of operating a striking device for an animal model of spinal cord injury as claimed in any one of claims 1-9, Fixing the limbs of an experimental animal on an animal model fixing table (7) through a binding belt (91); pushing the animal model fixing table (7) to the lower part of the firing pin (4), pressing the automatic tightening assembly (93) after the stop block (92) touches the side wall of the animal model fixing table (7), and further tightening the binding belt (91) by the automatic tightening assembly (93) to fix the experimental animal; setting the rotation direction and the rotation number of the driving parts (21 c) at the two ends of the control rod (21 b) to position the spinal cord position of the striker (4) striking the experimental animal; Releasing the first positioning component (1), and enabling a firing pin (4) connected with the first positioning component (1) to freely fall down to hit the spinal cord of the experimental animal; After the striker (4) strikes the spinal cord of the experimental animal once, the automatic restorer (5) drives the striker (4) and the positioning assembly I (1) connected with the striker (4) to move upwards; And step six, the unidirectional rotating rod (61) connected with the first positioning component (1) rotates after receiving the upward force, the unidirectional rotating rod (61) is locked with the unidirectional clamping piece (62), the first positioning component (1) and the firing pin (4) connected with the first positioning component (1) are fixed, the secondary firing pin is prevented from falling down to strike the spinal cord of the experimental animal, and at the moment, the animal model is successfully established.

Description

Beating device of spinal cord injury animal model and operation method Technical Field The invention belongs to the technical field of medicine, and particularly relates to a striking device of a spinal cord injury animal model and an operation method. Background Spinal cord injury is caused by the fact that spine shift or broken bone pieces protrude into vertebral canal after spine fracture to cause different degrees of injury to spinal cord or spinal nerves, is well generated at the junction of middle-lower cervical vertebra and thoracic and lumbar regions, has sensory and motor dysfunction, can generate quadriplegia in serious cases, can take medicines, operations and rehabilitation treatment, and is often researched by the animal model. The commonly used spinal cord injury animal model experiment is that the heavy object falls with acceleration and impacts on the spinal cord with certain elasticity, so that secondary impact is easily caused and accidental impact occurs. The patent with the publication number of CN107837124A discloses a striker for a spinal cord injury animal model and an operation method thereof, wherein the striker comprises a base, an XY slipway, a first handle, a second handle, a striking rod, a guide hole, a first striking rod clamping device, a second striking rod clamping device, a magnetostriction displacement sensor, a suspension block, a screw rod slipway, a connecting rod, an arc-shaped bracket and a control box. When the device is used, after the striking position of an experimental object is right below a striking rod, the control box controls the screw rod sliding table to drive the striking rod to rise to a set height, the control box controls the first striking rod clamping device to release the striking rod and the striking rod to fall freely, and finally, after the striking rod falls, the control box controls the second striking rod clamping device to clamp the rebound striking rod, the falling track of the striking rod is measured in real time through the magnetostriction displacement sensor, and according to the condition of the falling track, the control box controls the striking rod clamping device to clamp the striking rod before the second striking. However, the above-mentioned technical solution is provided with a suspension block at the upper end of the striking rod for obtaining the moving track of the striking rod, however, the suspension block may increase the weight of the striking rod, so that the result of striking the experimental object is inaccurate. Moreover, after the control box obtains displacement information of the suspension block, the second striking rod holding device is controlled to clamp the rebound striking rod, the structure is complex, the operation is complex, and if the information feedback of the suspension block is not timely enough, the secondary striking time of the striking rod is influenced. In the above technical scheme, if the secondary striking track of the striking rod is smaller, the sensor cannot accurately measure whether the animal model receives secondary striking, and an error is caused in judging whether the striking rod can strike secondarily, so that the animal model cannot be accurately prevented from being struck secondarily. Disclosure of Invention The invention aims to solve the problem that the traditional beating device of the spinal cord injury animal model can not accurately prevent experimental animals from being hit by a second time, and provides a beating device of the spinal cord injury animal model, which is characterized in that a one-way mechanism is additionally arranged on a striker positioner connected with a striker, and an automatic restorer is arranged on the striker; when the device is used, the first positioning component in the striker positioner is connected with the striker, after the striker falls down to strike the experimental animal, the automatic restorer drives the striker to move upwards, the first positioning component connected with the striker is also subjected to upward force, the first positioning component rotates upwards along with the unidirectional mechanism, and then the unidirectional mechanism locks the first positioning component, so that the second falling of the positioning component is prevented, and then the second striking of the striker connected with the first positioning component to the spinal cord of the experimental animal is prevented. Based on the technical thought, the technical scheme adopted by the invention is as follows: a striking device of a spinal cord injury animal model comprises a striker and an animal model fixing table, and further comprises: The firing pin positioner comprises a support frame, a first positioning assembly and a second positioning assembly, wherein the first positioning assembly and the second positioning assembly are arranged on the support frame up and down; the first positioning component is arranged at the upper end of the fir