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CN-122005323-A - Biological material with efficient peculiar smell removal function and preparation method and application thereof

CN122005323ACN 122005323 ACN122005323 ACN 122005323ACN-122005323-A

Abstract

The invention discloses a biological material with an efficient peculiar smell removal function, which comprises, by mass, 8-12 parts of a manganese precursor, 0.8-1.2 parts of a soluble metal salt, 4000-5000 parts of a dispersing agent and 90-100 parts of a regulator. The composite nano material taking small-particle-size thorn-convex manganese dioxide as a core and loading metal ions is prepared by simple processes of mixing, reacting, centrifuging and the like. The material can effectively remove bad breath through a double synergistic machine, namely, the manganese dioxide with small particle size captures odor-producing bacteria through physical adsorption, and simultaneously, released metal ions and hydrogen sulfide are subjected to chemical reaction to generate substances which are difficult to volatilize. The synergistic effect of the physical interception and the chemical conversion realizes the double effects of blocking the generation of peculiar smell from the source and eliminating the peculiar smell immediately. The product of the invention has the functions of biocompatibility and long-acting peculiar smell removal, can be widely applied to oral care products such as toothpaste, mouthwash and the like, and provides an innovative solution for the problem of oral peculiar smell.

Inventors

  • HUANG HAO
  • WU HAIBIN
  • ZHANG JIXIANG
  • GAO FANRU
  • YAN XIAOFEN
  • ZHENG ZHANHONG
  • YANG LI
  • WU WEIQI
  • CHEN QIAN

Assignees

  • 杭州医学院

Dates

Publication Date
20260512
Application Date
20260205

Claims (9)

  1. 1. The biological material with the efficient peculiar smell removal function is characterized by comprising, by mass, 8-12 parts of manganese precursor, 0.8-1.2 parts of soluble metal salt, 4000-5000 parts of dispersing agent and 90-100 parts of regulator.
  2. 2. The biological material with the efficient peculiar smell removing function according to claim 1, wherein the manganese precursor is at least one of potassium permanganate, manganese sulfate and manganese chloride, and the soluble metal salt is at least one of ferric salt, cupric salt, zinc salt and iridium salt.
  3. 3. The biomaterial with the efficient deodorizing function according to claim 2, wherein the manganese precursor is potassium permanganate and the soluble metal salt is copper salt.
  4. 4. The biological material with the efficient peculiar smell removing function according to claim 1, wherein the dispersing agent is at least one of deionized water, methanol water solution and ethanol water solution, and the regulator is at least one of oleic acid, stearic acid and palmitic acid.
  5. 5. The method for preparing the biological material with the efficient peculiar smell removal function according to any one of claims 1 to 4, which is characterized by comprising the following steps: (1) Dissolving a manganese precursor and soluble metal salt in a dispersing agent, and uniformly stirring; (2) And (3) adding a regulator into the step (1), and stirring and centrifugally washing the obtained mixture to obtain the biological material with the efficient peculiar smell removal function.
  6. 6. The method for preparing a biological material with efficient deodorizing function according to claim 5, wherein in the step (1), the stirring speed is 500-1000 rpm, and the stirring time is 0.4-0.6 h.
  7. 7. The method for preparing a biological material with efficient deodorizing function according to claim 5, wherein in the step (2), the stirring speed is 500-1000 rpm, and the stirring time is 4-6 hours.
  8. 8. The method for preparing a biological material with high-efficiency deodorizing function according to claim 5, wherein in the step (2), the centrifugal speed is 8000-12000 rpm, and the centrifugal time is 10-30 min.
  9. 9. The application of the biological material with the efficient deodorizing function in preparing an oral deodorizing antibacterial product according to any one of claims 1-4.

Description

Biological material with efficient peculiar smell removal function and preparation method and application thereof Technical Field The invention relates to the technical field of oral care materials, in particular to a biological material with an efficient peculiar smell removal function, and a preparation method and application thereof. Background The problem of bad breath affects social life and oral health of people for a long time, and one of the main causes is volatile sulfides such as hydrogen sulfide (H 2 S) generated by metabolism of bacteria in the oral cavity. The oral microbiota is complex, bacteria are propagated in a large quantity under a proper environment, and sulfur-containing amino acids are metabolized to produce H 2 S. Traditional oral care products depend on bacteriostats, aromatic agents and the like, the bacteriostats are easy to induce bacterial drug resistance due to a single action mechanism, the aromatic agents can only mask peculiar smell temporarily, and the problem of sulfide production by bacteria cannot be solved from the root. Chinese patent publication No. CN120267555A discloses a toothpaste added with a halitosis removing metaplasia removing composition and a preparation method thereof. The natural polyphenol bacteriostat and the plant source deodorant form a dual antibacterial deodorizing network, and the beta-cyclodextrin improves the drug loading rate of the bacteriostat through a molecular inclusion technology and is matched with the flora remodelling function of metaplasia. However, plant source components may cause allergy or irritation of oral mucosa, and the polyphenol bacteriostat may be absorbed and accumulated through mucosa after long-term use, and has some disadvantages. Chinese patent document with publication number CN119564518A discloses a toothpaste with bioactivity and freshness and a preparation method thereof. Wherein, the freshness-modifying material is triclosan which is an antibacterial agent modified on the surface of tourmaline powder, and endows the toothpaste with excellent antibacterial freshness performance. However, triclosan in the freshness-modified material is a broad-spectrum antibacterial agent, and long-term use of triclosan can damage the balance of oral flora and accelerate the generation of drug-resistant bacteria. In summary, the oral malodor-reducing materials of the prior art either have the risk of inducing resistance, disrupting the balance of the flora, or can only mask the malodor briefly, which can not radically solve the problem. Therefore, there is an urgent need in the art to develop a novel biomaterial that can avoid bacterial resistance, balance flora, and effectively and long-term remove oral malodor by dual routes of physical adsorption and chemical transformation. Disclosure of Invention In order to solve the technical problems, the invention provides a biological material with an efficient odor removal function, which can be used for efficiently removing the oral odor through a dual synergistic machine, wherein the small-particle-size manganese dioxide captures odor-producing bacteria through physical adsorption, and simultaneously released metal ions and hydrogen sulfide are subjected to chemical reaction to generate substances which are difficult to volatilize, so that the dual effects of blocking the generation of the odor from the source and immediately removing the odor are realized. The biological material with the efficient peculiar smell removal function comprises, by mass, 8-12 parts of manganese precursor, 0.8-1.2 parts of soluble metal salt, 4000-5000 parts of dispersing agent and 90-100 parts of regulator. In the invention, manganese precursor is reduced into manganese dioxide with extremely small molecular particle size, the manganese dioxide reacts with soluble metal salt to form the biological material with the high-efficiency peculiar smell removing function, after the biological material with the high-efficiency peculiar smell removing function is released, the small-particle-size manganese dioxide thorn convex structure increases the specific surface area of the material, and anchors the bacterial surface like a nano hook through physical adsorption, winding or embedding and the like to limit the movement and propagation of the material, so that the material has the capability of capturing bacteria and can effectively capture bacteria among teeth, and meanwhile, the soluble metal salt in the biological material with the high-efficiency peculiar smell removing function reacts with hydrogen sulfide in the oral cavity to consume the hydrogen sulfide in the oral cavity, thereby reducing the concentration of the hydrogen sulfide and removing the peculiar smell in the oral cavity. Preferably, the manganese precursor is at least one of potassium permanganate, manganese sulfate and manganese chloride. Preferably, the soluble metal salt is at least one of ferric salt, cupric salt, zinc salt and iridium salt. P