CN-122005383-A - Oily skin care composition and preparation method and application thereof

Abstract

The invention relates to the technical field of cosmetic efficacy raw materials, in particular to an oily skin care composition, a preparation method and application thereof. The invention provides an oily skin care composition which comprises, by mass, 95-99.75 parts of radix puerariae extract and 0.25-5 parts of carnosine. The invention adopts the combination of the pueraria extract and the carnosine in a specific proportion, has excellent effect of resisting squalene oxidation, can further realize excellent oil control effect, and remarkably enhances the nursing effect on oily skin. The preparation method of the oily skin care composition has simple process, is suitable for industrial production, and can have wide application prospect in cosmetics and/or medicines with oil control requirements.

Inventors

• ZHAO SIQI
• LIU YUEHENG
• WEI ZHENG
• QIU XIANRONG
• REN HANKUN
• ZHONG YURONG
• Xu Yongtou
• PAN MEIHONG

Assignees

• 北京东方淼森生物科技有限公司
• 广东袋鼠妈妈集团有限公司

Dates

Publication Date

20260512

Application Date

20260210

Claims (6)

1. 1. An oily skin care composition is characterized by comprising the following components in parts by mass: 95-99.75 parts of kudzuvine root extract and 0.25-5 parts of carnosine.
2. 2. The oily skin care composition of claim 1, wherein the method of preparing the kudzuvine root extract comprises: The preparation method comprises the steps of carrying out hot reflux extraction on a first mixed system of kudzuvine root, a solvent and active carbon, carrying out first solid-liquid separation, collecting a first liquid phase system, adopting an alkaline substance to adjust the pH value of the first liquid phase system to obtain a second mixed system, mixing the second mixed system with a first material, carrying out heat treatment on the first material, carrying out second solid-liquid separation on the first material, and collecting a second liquid phase system, wherein the first material is at least one selected from glycyrrhizic acid, glycyrrhetinic acid and glycyrrhetate.
3. 3. An oily skin care composition according to claim 2, wherein the kudzuvine root is subjected to a pulverization treatment in advance; Preferably, coarse powder with the particle size of 0.1-0.3 cm is adopted in the crushing treatment; preferably, the mass ratio of the kudzuvine root to the solvent to the activated carbon to the first material is 100 (1000-2000): (3.2-9.6): (8-64); Preferably, the glycyrrhetate comprises at least one of ammonium glycyrrhizate, sodium glycyrrhizate, monopotassium glycyrrhizate and dipotassium glycyrrhizate; preferably, the solvent includes at least one of water, monohydric alcohol and polyhydric alcohol; Preferably, the monohydric alcohol comprises at least one of methanol, ethanol, 1-propanol, 2-propanol, n-butanol, isobutanol, 1-pentanol, 2-pentanol, 3-pentanol, 1-hexanol, 2-hexanol, 3-hexanol, 1-heptanol, 2-heptanol, 3-heptanol, 4-heptanol, 1-octanol, 2-octanol, 3-octanol, 4-octanol, 1-nonanol, 2-nonanol, 3-nonanol, 4-nonanol, 5-nonanol, 1-decanol, 2-decanol, 3-decanol, 4-decanol, and 5-decanol; Preferably, the polyol comprises at least one of ethylene glycol, 1, 2-propylene glycol, 1, 3-propylene glycol, glycerol, 1, 2-butanediol, 1, 3-butanediol, 1, 4-butanediol, 1,2, 3-butanetriol, 1,2, 4-butanetriol, 1, 2-pentanediol, 1, 3-pentanediol, 1, 4-pentanediol, 1, 5-pentanediol, 2, 3-pentanediol, 2, 4-pentanediol, 1,2, 5-pentanediol, and 1, 2-hexanediol; Preferably, the solvent is at least one of monohydric alcohol and polyhydric alcohol and water, and the mass fraction of the monohydric alcohol and/or polyhydric alcohol is M, and M is more than or equal to 0.1% and less than or equal to 100%; Preferably, the temperature of the thermal reflux extraction is 75-85 ℃, and the time of the thermal reflux extraction is 110-130 min; Preferably, the first solid-liquid separation comprises coarse filtration and fine filtration which are sequentially carried out; Preferably, the coarse filtration adopts 200 mesh gauze, YB06 and F100 filter plates; preferably, the fine filtration adopts H70 cardboard; preferably, an alkaline substance is adopted to adjust the pH value of the first liquid phase system to 6.5-8; Preferably, the temperature of the heat treatment is 85-90 ℃; Preferably, the second solid-liquid separation adopts H70 filter paper board; preferably, the turbidity of the second liquid phase system is lower than 2FNU; preferably, the method further comprises the step of heating and sterilizing the second liquid phase system; preferably, the temperature of the heating sterilization is 80-85 ℃, and the time of the heating sterilization is 30-45 min.
4. 4. A method for preparing an oily skin care composition according to any one of claims 1 to 3, comprising uniformly mixing the extract of Pueraria lobata with carnosine.
5. 5. The method of preparing an oily skin care composition according to claim 4, wherein the pueraria extract is sterilized after being uniformly mixed with carnosine; Preferably, the sterilization temperature is 75-79 ℃, and the sterilization time is 20-40 min.
6. 6. Use of an oily skin care composition according to any one of claims 1 to 3 or prepared by the process of claim 4 or 5 for the preparation of cosmetics and/or pharmaceuticals.

Description

Oily skin care composition and preparation method and application thereof Technical Field The invention relates to the technical field of cosmetic efficacy raw materials, in particular to an oily skin care composition, a preparation method and application thereof. Background The combined effect of skin lipid metabolism abnormality, especially hypersecretion and squalene oxidation reaction is a key pathological basis for the occurrence and development of skin problems such as oily skin, acne and the like. Squalene is used as a main nonpolar lipid naturally existing in sebum, accounts for about 10% -14% of the total amount of skin surface lipid, has a chemical structure containing six double bonds, is extremely vulnerable to ultraviolet radiation, environmental pollutants and Reactive Oxygen Species (ROS) generated by microorganisms on the skin surface (such as propionibacterium acnes), and generates lipid peroxidation to generate squalene hydroperoxide (squalene monohydroperoxide, SQOOH) and other oxidation products. Research shows that the oxidosqualene has obvious inflammatory property and acne promotion property, can induce keratinocytes to produce inflammatory factors such as interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha) and the like, promote abnormal keratinization of hair follicles, block pores and further induce or aggravate acne lesions. The prior oil control skin care technology is mainly focused on physical oil absorption, sebum synthesis inhibition or sebaceous gland activity regulation, for example, zinc salt, nicotinamide, salicylic acid and other components are adopted to reduce sebum secretion or accelerate cutin exfoliation. However, these methods generally ignore the problem of secondary damage caused by squalene that has been secreted to the skin surface during subsequent oxidation. Even if the total sebum is controlled, residual squalene can continue to oxidize under external stimuli, resulting in elevated levels of oxidative stress and chronic low inflammatory states. In view of this, the present invention has been made. Disclosure of Invention An object of the present invention is to provide an oily skin care composition having an excellent effect of resisting squalene oxidation, which can further achieve an excellent oil control effect. Another object of the present invention is to provide a method for preparing the above oily skin care composition, which is simple in process and suitable for industrial production. A third object of the present invention is to provide an application of the above-mentioned oily skin care composition in the preparation of cosmetics and/or pharmaceuticals, which has a wide application prospect in cosmetics and/or pharmaceuticals having oil control requirements due to its excellent anti-squalene oxidation effect. In order to achieve the above purpose, the invention provides an oily skin care composition, which comprises the following components in parts by mass: 95-99.75 parts of kudzuvine root extract and 0.25-5 parts of carnosine. The oily skin care composition comprises the pueraria extract and the carnosine in a specific proportion, has an excellent squalene oxidation resistance effect, can further realize an excellent oil control effect, and remarkably enhances the care effect on oily skin. The invention also provides a preparation method of the oily skin care composition, which comprises the steps of uniformly mixing the pueraria extract and the carnosine. In another aspect, the invention provides the use of an oily skin care composition as described above in the preparation of a cosmetic and/or pharmaceutical product. The oily skin care composition has excellent effect of resisting squalene oxidation, and can be widely applied to cosmetics and/or medicines with oil control requirements. Compared with the prior art, the invention has the beneficial effects that: The invention adopts the combination of the pueraria extract and the carnosine in a specific proportion, has excellent effect of resisting squalene oxidation, can further realize excellent oil control effect, and remarkably enhances the nursing effect on oily skin. The preparation method of the composition has simple process, is suitable for industrial production, and can have wide application prospect in cosmetics and/or medicines with oil control requirements. Drawings In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are needed in the description of the embodiments or the prior art will be briefly described, and it is obvious that the drawings in the description below are some embodiments of the present invention, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art. FIG. 1 is a graph showing the results of an anti-squalene oxidation test according to an embodiment of the present invention. Detailed Description The technic