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CN-122005401-A - Refined extract for activating hair follicle and preventing hair loss and raising hair

CN122005401ACN 122005401 ACN122005401 ACN 122005401ACN-122005401-A

Abstract

The invention discloses a refined extract for activating hair follicles and preventing hair loss and hair growth, and relates to the technical field of hair care agents. The composition comprises the following components of echinacea purpurea extract, silybum marianum extract, polygonum multiflorum extract, pumpkin seed extract, ganoderan and sea buckthorn fruit extract. According to the invention, the echinacea purpurea extract, the silybum marianum extract, the polygonum multiflorum extract, the pumpkin seed extract, the ganoderan and the seabuckthorn fruit extract are scientifically compounded, and the components are synergistic, so that the technical effects of activating hair follicles and preventing hair loss and growing hair are achieved together.

Inventors

  • SUN KAIJUN

Assignees

  • 广州骅美医药生物科技有限公司

Dates

Publication Date
20260512
Application Date
20260323

Claims (10)

  1. 1. A composition for activating hair follicle, preventing hair loss and promoting hair growth is characterized by comprising the following components of echinacea purpurea extract, silybum marianum extract, polygonum multiflorum extract, pumpkin seed extract, ganoderan and seabuckthorn fruit extract.
  2. 2. The composition of claim 1, wherein the Echinacea extract is prepared by pulverizing Echinacea, mixing with ethanol aqueous solution, gradient extracting for 1-3 times, mixing the extracts, and concentrating.
  3. 3. The composition of claim 1, wherein the silybum marianum extract is prepared by pulverizing silybum marianum fruit, mixing with water, and adding laccase, bromelain and pectin lyase for enzymolysis.
  4. 4. The composition according to claim 1, which comprises the following raw materials, by mass, 2-10 parts of echinacea purpurea extract, 1-6 parts of silybum marianum extract, 10-20 parts of polygonum multiflorum extract, 2-10 parts of pumpkin seed extract, 3-8 parts of ganoderan and 8-15 parts of seabuckthorn fruit extract.
  5. 5. A process for preparing a composition according to any one of claims 1 to 4, comprising the step of mixing the raw materials.
  6. 6. A essence for activating hair follicles and preventing hair loss and development, characterized in that the raw materials of the essence comprise the composition of any one of claims 1-4 and auxiliary materials acceptable in the cosmetic field.
  7. 7. The essence according to claim 6, characterized in that the mass of the composition is 2% -5% of the total mass of the raw materials of the essence.
  8. 8. The essence according to claim 6, characterized in that the cosmetic field acceptable adjuvants comprise solvents, hair conditioning agents and cooling agents.
  9. 9. The essence according to claim 8, wherein the solvent is at least one selected from the group consisting of 1, 2-hexanediol, 1, 3-propanediol, butanediol, glycerol and water, the hair conditioner is at least one selected from the group consisting of niacinamide, panthenol, cyclodextrin, caffeine and allantoin, and the cooling agent is menthol.
  10. 10. Use of a composition according to any one of claims 1 to 4 or a essence according to any one of claims 6 to 9 for the preparation of a product for activating hair follicles, preventing hair loss and hair growth.

Description

Refined extract for activating hair follicle and preventing hair loss and raising hair Technical Field The invention relates to the technical field of hair care agents, and relates to a hair follicle activating and hair loss preventing extract, in particular to a hair follicle activating and hair loss preventing composition, a hair loss preventing extract and application. Background In terms of the pathogenesis of hair loss, hair loss is not a single disorder, but is the result of a multi-factor interlacing action, where hair follicle dysfunction is a core cause. The most common androgenetic alopecia accounts for more than 90% of all alopecia cases, is closely related to genetic genes, hair follicles of patients are abnormally sensitive to androgens, hair follicles are gradually miniaturized, hair is degenerated from coarse and hard final hair to fine and soft vellus hair, alopecia areata is caused by immune system disorder, T lymphocyte mistakes attack hair follicles to cause inflammation, and then local alopecia is caused, telogen alopecia is mostly induced by factors such as postpartum hormone fluctuation, mental high pressure, rapid weight loss and the like, and the hair loss is obviously increased. In addition, imbalance in scalp microenvironment, insufficient nutrition supply to hair follicles, dormancy of hair follicle stem cells, apoptosis of hair papilla cells, etc., may also lead to decreased hair follicle activity, eventually leading to hair loss or hair rarefaction. Research shows that hair follicle stem cells in the bald scalp do not disappear, but only the metabolic mode is locked in a dormant state, a growth program cannot be started, and how to effectively wake dormant hair follicles and reverse hair follicle micromation becomes a core break of the anti-hair loss and hair growing technology. At present, the anti-hair-loss and hair-growing technology is mainly divided into four directions of chemical drug intervention, surgical operation, physical therapy and natural component application, but obvious limitations exist in all directions. In the field of chemical medicines, minoxidil and finasteride are main therapeutic medicines, wherein minoxidil needs to be used for a long time or even for a whole life, alopecia is easy to rebound rapidly after stopping the medicine, and side effects such as scalp irritation and folliculitis are possibly caused, scalp barrier injury is further aggravated by solvents such as propylene glycol and ethanol which are commonly used in a formula, and finasteride is mainly used for male androgenetic alopecia, has side effects such as sexual dysfunction and the like, and is completely forbidden for females. Although the surgical hair implantation operation can quickly improve the appearance, the surgical hair implantation operation has the problems of high cost, dependence on donor hair follicle resources, long postoperative recovery period, possible scar left or infection risk and the like, and the problem of continuous atrophy of the primary hair follicle cannot be solved. The physical therapy such as low-energy laser has high safety but weak single use effect, is effective only on early alopecia, and needs to be matched with medicines for use. The natural component classification anti-drop products become research hot spots in recent years due to higher safety, but the natural component classification anti-drop products still have a plurality of technical defects. For example, chinese patent application CN118662418a discloses a natural plant extract composition for preventing alopecia and fixing hair, which has high-efficient inhibition effect on 5A-reductase and main microorganisms such as malassezia furfur, propionibacterium acnes and staphylococcus aureus, which are used for inducing seborrheic alopecia, through reasonable proportioning synergistic effect of hypericum perforatum extract, guaiacum extract, mangiferin peel extract, polygonum multiflorum extract, biota orientalis extract and ginger extract seven plant extract, thereby reducing the occurrence probability of seborrheic alopecia. Chinese patent application CN101098677a discloses the use of plant extracts from ajuga plants in the manufacture of a composition for preventing or treating hair loss. Chinese patent application CN118477021A is a shampoo containing plant extract for preventing alopecia and relieving itching and its preparation method, and contains the following components of plant extract, surfactant, humectant, conditioner, anti-dandruff antipruritic, ammonium hydroxide, citric acid, preservative, essence and purified water, in which the plant extract is formed from ginseng (PANAXGINSENG) root extract, alpinia zerumbet (ALPINIASPECIOSA) leaf extract and cyperus esculentus (CYPERUSESCULENTUS) root oil according to the mass ratio of 2-3:2-5:1, the conditioner includes chitosan, histidine and amino-terminal polydimethylsiloxane, and the anti-dandruff antipruritic is piroctone olamine. On the