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CN-122005402-A - Anti-glycation composition applicable to sensitive muscles and application thereof

CN122005402ACN 122005402 ACN122005402 ACN 122005402ACN-122005402-A

Abstract

The invention relates to an anti-glycation composition applicable to sensitive muscles and application thereof, and belongs to the technical field of cosmetics. The anti-glycation composition suitable for sensitive muscles comprises, by mass, 0.01-0.5 part of ascorbyl polypeptide, 0.5-2 parts of ginseng root extract, 0.1-2 parts of acetyl tetrapeptide-2, and 0.1-5 parts of andrographis paniculata leaf extract. The anti-glycation composition suitable for the sensitive muscles has remarkable anti-glycation effect, can remarkably improve skin elasticity, has a certain repairing effect, and is suitable for the sensitive muscles.

Inventors

  • ZHANG JIANHUA
  • GUO WENJIAO

Assignees

  • 溪木源生物科技集团有限公司

Dates

Publication Date
20260512
Application Date
20260327

Claims (10)

  1. 1. An anti-glycation composition suitable for sensitive muscles is characterized by comprising the following components in parts by mass: 0.01-0.5 part of ascorbyl polypeptide; 0.5-2 parts of ginseng root extract; 0.1-2 parts of acetyl tetrapeptide-2; 0.1-5 parts of andrographis paniculata leaf extract.
  2. 2. The composition of claim 1, comprising the following components in parts by mass: 0.05-0.2 part of ascorbyl polypeptide; 0.8-1.2 parts of ginseng root extract; 0.5-1 part of acetyl tetrapeptide-2; 0.5-2 parts of andrographis paniculata leaf extract.
  3. 3. Use of a composition according to claim 1 or 2 for the preparation of a cosmetic product with anti-ageing effect.
  4. 4. The use according to claim 3, wherein the cosmetic formulation comprises any one of an emulsion, a face cream, an eye cream, a face mask.
  5. 5. An emulsion having anti-aging effect comprising 2 to 5wt% of the composition of claim 1 or 2.
  6. 6. The emulsion of claim 5, further comprising a humectant, an emollient, an emulsifier, an antioxidant, a thickener, a pH adjustor, a chelating agent, deionized water.
  7. 7. The emulsion of claim 6, The humectant comprises at least one of allantoin, butanediol, hexanediol, glycerol and betaine; The emollient comprises at least one of di-PEG-15 methyl ether polydimethylsiloxane, caprylic/capric triglyceride, squalane, isohexadecane, begonia seed oil, C10-18 fatty acid triglyceride, butyrospermum parkii fruit lipid, hydrogenated polyisobutene.
  8. 8. The emulsion of claim 6, The emulsifier comprises at least one of hydrogenated lecithin, C14-22 alcohol/C12-20 alkyl glucoside, cetostearyl alcohol/cetostearyl glucoside, polyglycerol-6 distearate, sodium stearyl glutamate, arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, cetostearyl alcohol oliveate/sorbitan oliveate; the antioxidant comprises at least one of p-hydroxyacetophenone, tocopherol acetate, sodium sulfite, sodium metabisulfite and pentaerythritol tetra (di-tert-butyl hydroxy hydrocinnamate).
  9. 9. The emulsion of claim 6, The thickener comprises at least one of carbomer, xanthan gum, sodium polyacrylate, ammonium acryloyldimethyl taurate/VP copolymer, acrylic ester copolymer, sclerotium gum, carboxymethyl cellulose, ethyl cellulose, tara gum, guar gum, gellan gum and carrageenan.
  10. 10. The emulsion of claim 6, The pH regulator comprises at least one of arginine and tromethamine; the chelating agent includes EDTA-2Na.

Description

Anti-glycation composition applicable to sensitive muscles and application thereof Technical Field The invention relates to the technical field of cosmetics, in particular to an anti-glycation composition applicable to sensitive muscles and application thereof. Background Skin glycation refers to the combination of in vivo sugar with proteins in the skin to produce AGEs (advanced glycation end products) which in turn destroy collagen and elastic fibers of the skin, and protein denaturation accelerates skin aging. The mechanism of AGEs generation can be divided into three phases. In the primary stage, the carbonyl of the reducing sugar reacts with the N-terminal amino group of the protein to generate schiff base, and the schiff base is further rearranged due to instability to form a more stable Amadori product. This process is accompanied by the generation of a large number of free Radicals (ROS). Intermediate stage Amadori products are fragmented or modified to different dicarbonyl compounds (methylglyoxal, glyoxal, 3-deoxyglucosone, etc.). In the final stage, dicarbonyl compounds form isomers with arginine and lysine residues of proteins, and finally AGEs are generated. AGEs, after accumulating in vivo, can interact with their receptor RAGE, triggering a series of inflammatory and oxidative stress reactions. The invention provides a composition which can act at each stage of AGEs generation, and can more effectively inhibit the generation of the AGEs, play an anti-saccharification role and further relieve skin aging phenomenon caused by saccharification. Disclosure of Invention The invention aims to overcome the defects of the prior art and provide an anti-glycation composition applicable to sensitive muscles and application thereof. In order to achieve the above purpose, the technical scheme adopted by the invention is as follows: In a first aspect, the invention provides an anti-glycation composition suitable for sensitive muscles, which comprises the following components in parts by mass: 0.01-0.5 part of ascorbyl polypeptide; 0.5-2 parts of ginseng root extract; 0.1-2 parts of acetyl tetrapeptide-2; 0.1-5 parts of andrographis paniculata leaf extract. Preferably, the anti-glycation composition suitable for the sensitive muscle comprises the following components in parts by mass: 0.05-0.2 part of ascorbyl polypeptide; 0.8-1.2 parts of ginseng root extract; 0.5-1 part of acetyl tetrapeptide-2; 0.5-2 parts of andrographis paniculata leaf extract. According to the invention, specific components are selected for matching, so that the obtained anti-saccharification composition has a remarkable anti-saccharification effect, can remarkably improve skin elasticity, has a certain repairing effect, and is suitable for sensitive muscles. In a second aspect, the present invention provides the use of a composition according to the first aspect for the preparation of a cosmetic product having anti-ageing efficacy. Preferably, the formulation of the cosmetic comprises any one of emulsion, face cream, eye cream and facial mask. In a third aspect, the present invention provides an emulsion having anti-ageing efficacy comprising from 2% to 5% by weight of the composition of the first aspect. Preferably, the emulsion further comprises a humectant, an emollient, an emulsifier, an antioxidant, a thickener, a pH regulator, a chelating agent and deionized water. Preferably, the humectant comprises at least one of allantoin, butanediol, hexanediol, glycerol, betaine. Preferably, the emollient comprises at least one of bis-PEG-15 methyl ether polydimethylsiloxane, caprylic/capric triglyceride, squalane, isohexadecane, begonia seed oil, C10-18 fatty acid triglycerides, butyrospermum parkii fruit lipid, hydrogenated polyisobutene. Preferably, the emulsifier comprises at least one of hydrogenated lecithin, C14-22 alcohol/C12-20 alkyl glucoside, cetostearyl alcohol/cetostearyl glucoside, polyglycerol-6 distearate, sodium stearyl glutamate, arachidyl alcohol/behenyl alcohol/arachidyl glucoside, cetostearyl olive oleate/sorbitan olive oleate. Preferably, the antioxidant comprises at least one of p-hydroxyacetophenone, tocopherol acetate, sodium sulfite, sodium metabisulfite, pentaerythritol tetrakis (bis-tert-butylhydroxyhydrocinnamate). Preferably, the thickener comprises at least one of carbomer, xanthan gum, sodium polyacrylate, ammonium acryloyldimethyl taurate/VP copolymer, acrylic ester copolymer, small sclerotium gum, carboxymethyl cellulose, ethyl cellulose, tara gum, guar gum, gellan gum, and carrageenan; Preferably, the pH regulator comprises at least one of arginine and tromethamine; Preferably, the chelating agent comprises EDTA-2Na. Compared with the prior art, the invention has the beneficial effects that: The invention provides an anti-glycation composition applicable to sensitive muscles, which consists of ascorbyl polypeptide, ginseng root extract, acetyl tetrapeptide-2 and andrographis paniculata leaf extract. The a