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CN-122005440-A - Externally applied preparation for treating meniscus sports injury and preparation method thereof

CN122005440ACN 122005440 ACN122005440 ACN 122005440ACN-122005440-A

Abstract

The invention discloses an external application preparation for treating meniscus sports injury and a preparation method thereof, and relates to the technical field of meniscus external application preparations. The invention discloses a diclofenac sodium gel emulsifiable paste, a Chinese patent medicine patch, an auxiliary agent A and an auxiliary agent B, wherein the diclofenac sodium gel emulsifiable paste comprises the following raw materials of diclofenac sodium, propylene glycol, carbomer, triethanolamine, glycerin, absolute ethyl alcohol, menthol and water, the Chinese patent medicine patch comprises the following raw materials of frankincense, myrrh, angelica, szechuan lovage rhizome, borneol and menthol, the auxiliary agent A comprises the following raw materials of nutgrass galingale rhizome, dahurian angelica root, ground beetle and kudzuvine root, and the auxiliary agent B comprises the following raw materials of safflower and dried ginger. The invention realizes the Chinese-western combined treatment by preparing the western medicine plaster and the Chinese medicine plaster, and also realizes the use of different patients in different proportions according to the split packaging of the Chinese medicine components according to the medicine effect, thereby solving the problems that the medicine effect of the existing external application preparation is single, the composition matching application can not be carried out under the condition of adapting to different patients, the Chinese-western combined application can not be realized, and the like.

Inventors

  • GAO YI

Assignees

  • 高溢

Dates

Publication Date
20260512
Application Date
20260225

Claims (9)

  1. 1. An external application preparation for treating meniscus sports injury is characterized by comprising diclofenac sodium gel cream, a Chinese patent medicine patch, an auxiliary medicine A and an auxiliary medicine B; The diclofenac sodium gel latex comprises, by weight, 1-1.5 parts of diclofenac sodium, 12-18 parts of propylene glycol, 1-1.5 parts of carbomer, 1-1.5 parts of triethanolamine, 5-8 parts of glycerin, 1-2 parts of absolute ethyl alcohol, 0.5-1 part of menthol and 70-75 parts of water; the Chinese patent medicine patch comprises the following raw materials, by weight, 5-10 parts of frankincense, 5-10 parts of myrrh, 10-15 parts of Chinese angelica, 3-5 parts of szechuan lovage rhizome, 1-3 parts of borneol and 1-2 parts of menthol; The auxiliary medicine A comprises the following raw materials, by weight, 3-5 parts of nutgrass galingale rhizome, 3-5 parts of dahurian angelica root, 2-3 parts of ground beetle and 2-3 parts of kudzuvine root; the auxiliary drug B comprises the following raw materials, by weight, 4-8 parts of safflower and 5-10 parts of dried ginger.
  2. 2. The external preparation for treating meniscus injury according to claim 1, wherein the diclofenac sodium gel cream is firstly smeared on the lower surface of a backing substrate and uniformly smeared, the backing substrate is applied on the meniscus injury position, and after the application for 3-5h, the Chinese patent medicine patch is poured on the upper surface of the backing substrate and wets the backing substrate; Or mixing the auxiliary medicine A and/or the auxiliary medicine B into the Chinese patent medicine patch according to the proportion according to the illness state of the meniscus injury patient to form a new Chinese patent medicine, pouring the new Chinese patent medicine on the upper surface of the backing substrate and soaking the backing substrate after the diclofenac sodium gel cream is applied for 3-5 hours.
  3. 3. The external preparation for treating meniscus injury according to claim 2, wherein 1 part of the diclofenac sodium gel cream has a diclofenac sodium content of 1-1.5 g, and 1-3 parts of the diclofenac sodium gel cream is used according to the size of the meniscus injury surface of the patient and the age and weight of the patient; the usage amount of the Chinese patent medicine patch, the auxiliary medicine A and the auxiliary medicine B is matched with that of the diclofenac sodium gel cream, so that the backing substrate is ensured to be fully soaked.
  4. 4. A topical preparation for treating meniscal sports injury according to claim 2 or claim 3 wherein the upper surface of the backing substrate is provided with a removable medical mild heat application which releases heat at a temperature of from 35 to 45 ℃.
  5. 5. The external application preparation for treating meniscus injury according to claim 1, wherein the Chinese medicinal components in the Chinese medicinal patch, the auxiliary medicine A and the auxiliary medicine B are crushed and dissolved in sterile water or ethanol solution, and the solution is heated and dissolved to form corresponding medicinal liquid, and the medicinal liquid prepared by the Chinese medicinal patch, the auxiliary medicine A and the auxiliary medicine B is packaged in corresponding small packaging bags.
  6. 6. A preparation method of an external application preparation for treating meniscus sports injury, which is characterized by adopting the raw materials of claim 1 and comprising the following specific steps: 1, weighing 1-1.5 parts of diclofenac sodium, 12-18 parts of propylene glycol, 1-1.5 parts of carbomer, 1-1.5 parts of triethanolamine, 5-8 parts of glycerol, 1-2 parts of absolute ethyl alcohol and 0.5-1 part of menthol, injecting 70-75 parts of sterile water into a stirring and dissolving tank, adding the diclofenac sodium into the dissolving tank for stirring and dissolving, adding the propylene glycol, the triethanolamine, the glycerol, the absolute ethyl alcohol and menthol for stirring and dissolving, slowly adding the carbomer for stirring and dissolving, concentrating to form paste, and subpackaging the diclofenac sodium gel cream into quantitative bags; S2, weighing 5-10 parts of frankincense, 5-10 parts of myrrh, 10-15 parts of angelica, 3-5 parts of ligusticum wallichii, 1-3 parts of borneol and 1-2 parts of menthol, stir-frying the frankincense and the myrrh at a low temperature until the surfaces of the frankincense and the myrrh are slightly melted, generating white smoke, taking out and cooling, crushing, respectively crushing the angelica, the ligusticum wallichii, the borneol and the menthol, uniformly mixing all the crushed raw materials, dissolving in 100-120 parts of sterile water, stirring and dissolving at 35-40 ℃ to prepare a Chinese patent medicine patch solution, and subpackaging in a quantitative bag to prepare the Chinese patent medicine patch; S3, weighing 3-5 parts of nutgrass galingale rhizome, 3-5 parts of dahurian angelica root, 2-3 parts of ground beetle and 2-3 parts of kudzuvine root, respectively crushing, uniformly mixing, dissolving in 75% ethanol solution, soaking for 5-7 days, opening once a day, stirring for 5-10 minutes, covering with a seal, filtering, concentrating the supernatant, diluting with 50-60 parts of sterile water to obtain a liquid medicine, and subpackaging in quantitative bags to prepare an auxiliary medicine A; s4, weighing 4-8 parts of safflower and 5-10 parts of dried ginger, respectively crushing and uniformly mixing, dissolving in 30-50 parts of sterile water, heating and dissolving at 50-55 ℃ to prepare a liquid medicine, and subpackaging in quantitative bags to prepare an auxiliary medicine B; S5, mixing the Chinese patent medicine patch, the auxiliary medicine A and the auxiliary medicine B according to the proportion, wherein the bag mixing proportion of the Chinese patent medicine patch, the auxiliary medicine A and the auxiliary medicine B is (1-3): 0-2: (0-2).
  7. 7. The method for preparing the external preparation for treating the meniscus injury according to claim 6, wherein the diclofenac sodium gel cream prepared in the step S1 is uniformly smeared on the lower surface of a backing substrate before the external preparation is applied to the meniscus injury position of a patient, so that the lower surface of the backing substrate is completely smeared with the diclofenac sodium gel cream, the diclofenac sodium gel cream on the lower surface of the backing substrate is applied to the meniscus injury position, and after the application for 3-5 hours, the mixed liquid medicine of the Chinese patent medicine patch, the auxiliary medicine a and the auxiliary medicine B is dripped on the upper surface of the backing substrate, so that the mixed liquid medicine wets the residual diclofenac sodium gel cream, and the mixed liquid medicine is mixed with the diclofenac sodium gel cream when contacting skin.
  8. 8. The method of preparing an external preparation for treating meniscal sports injury as claimed in claim 7, wherein said Chinese patent medicine patch, adjuvant a and adjuvant B are used in combination in a male patient and said Chinese patent medicine patch and adjuvant a are used in combination in a female patient; if the meniscus injury of the patient is slight, the Chinese patent medicine patch is only required to be dripped on the backing substrate; If the meniscus injury of the patient needs to be treated slowly, an auxiliary drug A or/and an auxiliary drug B needs to be mixed into the Chinese patent medicine patch.
  9. 9. The method for preparing a topical preparation for treating meniscal sports injury according to claim 7, wherein a protective patch is adhered to the upper surface of the backing substrate during the application of the backing substrate, wherein the protective patch comprises a common protective patch and a medical mild hot compress patch, and the medical mild hot compress patch is adhered to the upper surface of the backing substrate when the ambient temperature is lower than 15 ℃.

Description

Externally applied preparation for treating meniscus sports injury and preparation method thereof Technical Field The invention belongs to the technical field of meniscus external application preparations, and particularly relates to an external application preparation for treating meniscus sports injury and a preparation method thereof. Background The meniscus is an auxiliary structure between the knee joint femur and tibia, is a pair of half-moon shaped cartilages, has thicker edges and thinner middle, and is filled on the tibia condyles on two sides. The medial meniscus is larger, the lateral margin of the tibia is tightly connected with the medial collateral ligament, so the movable range is small, and the lateral meniscus is not connected with the lateral collateral ligament, so the movable range is large. In knee extension Qu Shi, the meniscus moves between the joints, has the function of stabilizing the joints and reduces friction on the articular surfaces. When the meniscus is torn lightly, pain can be eliminated quickly, and the pain can be treated according to general traumas. If "cross-locking" occurs, the surgical removal should be performed immediately. If the pain is serious after injury, the bleeding phenomenon exists in the joints, namely, the knee joint is wrapped by a pressure bandage, so that the continued bleeding is prevented, and the knee joint is immediately sent to a hospital for treatment. If the joint is not painful after two weeks of injury, but there is still a cross-lock sound at the time of examination, the meniscus is surgically resected. After excision, a new half-moon cartilage can be regenerated at the residual cartilage bottom, and the half-moon can also function as a meniscus. Whether surgical or non-surgical, the patient can still participate in physical exercise as long as the patient is after the laceration heals. When the external preparation is applied, the preparation needs to be absorbed by the skin sufficiently and enter the meniscus for treatment. The purchased external application preparation formula is fixed and cannot be adjusted, only the sex, the age, the weight and the injury degree of different meniscus injury patients are different by purchasing other specifications or products, the requirements on the applied ointment or medicament are different, the external application preparation can be optimally adapted to the patients to treat the meniscus injury, but most of the external application preparations on the market do not adapt to the conditions of the drug preparation raw materials for the conditions of the patients, and only the forbidden or cautious use of the patients can be written. In addition, the traditional Chinese medicine plaster and the western medicine plaster cannot be directly mixed for plaster first, because the efficacy may be too violent, resulting in injury of meniscus. However, western medicines and traditional Chinese medicines can be applied to an affected part at intervals, the existing external application preparation is not written or a method and a formula for combining the two are provided, and only can be operated according to doctors, so that patients can be required to go to a hospital for diagnosis after meniscus injury, and basic treatment cannot be carried out by directly purchasing the external application preparation. Disclosure of Invention The invention aims to provide an external application preparation for treating meniscus sports injury and a preparation method thereof, wherein western medicine plaster and traditional Chinese medicine plaster are prepared to realize Chinese and western combined treatment, chinese medicine components are packaged according to medicine effects, different patients are used in different proportions, and the problems that the traditional external application preparation is single in medicine effect, cannot be matched with different patients to carry out component matching application, cannot realize Chinese and western combined application and the like are solved. In order to solve the technical problems, the invention is realized by the following technical scheme: The invention relates to an external application preparation for treating meniscus sports injury, which comprises diclofenac sodium gel cream, chinese patent medicine patches, an auxiliary agent A and an auxiliary agent B; The diclofenac sodium gel latex comprises, by weight, 1-1.5 parts of diclofenac sodium, 12-18 parts of propylene glycol, 1-1.5 parts of carbomer, 1-1.5 parts of triethanolamine, 5-8 parts of glycerin, 1-2 parts of absolute ethyl alcohol, 0.5-1 part of menthol and 70-75 parts of water; the Chinese patent medicine patch comprises the following raw materials, by weight, 5-10 parts of frankincense, 5-10 parts of myrrh, 10-15 parts of Chinese angelica, 3-5 parts of szechuan lovage rhizome, 1-3 parts of borneol and 1-2 parts of menthol; The auxiliary medicine A comprises the following raw materials, by weight, 3-