CN-122005519-A - Flushing fluid for sodium dipping treatment of emergency environment of sodium-related factory building and preparation method thereof

Abstract

The invention relates to a flushing fluid for sodium dipping treatment in an emergency environment of a sodium-related factory building and a preparation method thereof, wherein the flushing fluid comprises the following components, by concentration, 15-17 g/L of ethylenediamine tetraacetic acid, 4.5-5.5 g/L of N-acetyliminoethylenediamine triacetic acid, 52-56 g/L of amino acid and auxiliary components for bacteriostasis and anesthesia, the pH value of the flushing fluid is 6-7, and the osmotic pressure of the flushing fluid is 850-900mOsm/L. The flushing fluid disclosed by the invention can be applied to on-site emergency treatment and medical rescue after sodium contaminates human skin and eyes in a sodium-related factory environment, so that secondary damage (severe reaction of sodium and water) possibly caused by direct water flushing is reduced, the flushing effect is obviously improved, the damage caused by strong alkali burn and thermal burn caused by sodium contaminates is relieved, and the wound healing is obviously accelerated.

Inventors

• ZHANG TENG
• HAN FANGJIE
• LIU XINRAN
• JIANG SHEN
• GU XIAONA
• SU LIXIA
• XUE XIANGMING
• BAI XUFANG
• YANG KAI
• ZHAN JINGMING

Assignees

• 中国辐射防护研究院

Dates

Publication Date

20260512

Application Date

20251229

Claims (10)

1. 1. The flushing fluid for sodium dipping treatment in the emergency environment of the sodium-related factory building is characterized by comprising the following components in percentage by concentration: 15-17 g/L of ethylenediamine tetraacetic acid; 4.5-5.5 g/L of N-acetamido ethylenediamine triacetic acid; 52-56 g/L of amino acid; auxiliary components for bacteriostasis and anesthesia; The pH value of the flushing liquid is 6-7.
2. 2. The rinse solution of claim 1, wherein the amino acids include ergothioneine and glycine.
3. 3. The rinse solution of claim 2, wherein the glycine concentration is 46-48 g/L.
4. 4. The rinse solution of claim 2, wherein the concentration of ergothioneine is 6-8 g/L.
5. 5. The irrigation fluid of claim 1 wherein the adjunct ingredients include lidocaine and mupirocin.
6. 6. The rinse solution of claim 5, wherein the mupirocin concentration is 0.5-1.5 g/L.
7. 7. The rinse solution of claim 5, wherein the lidocaine concentration is 4-5 g/L.
8. 8. The irrigation fluid of claim 1, wherein the irrigation fluid has an osmolarity of 850-900mOsm/L.
9. 9. A method of preparing a rinse solution according to any one of claims 1 to 8, comprising the steps of: Weighing ethylenediamine tetraacetic acid, N-acetyliminoethylenediamine triacetic acid, glycine and ergothioneine in a beaker by an analytical balance according to the proportion, adding boiled and sterilized sterile purified water, fully stirring, and performing ultrasonic dissolution until all components are fully dissolved to obtain a uniformly mixed main solution; Transferring the main solution to a volumetric flask for constant volume; Weighing mupirocin and lidocaine into a beaker, adding absolute ethyl alcohol into the beaker, fully stirring, and carrying out ultrasonic dissolution until the mupirocin and the lidocaine are fully dissolved to obtain an auxiliary component solution; and adding the auxiliary component solution into the main solution, uniformly mixing, and adjusting the pH value of the solution to 6-7 to obtain the flushing liquid.
10. 10. The method of claim 9, wherein the temperature of the ultrasonic dissolution is 40 ℃.

Description

Flushing fluid for sodium dipping treatment of emergency environment of sodium-related factory building and preparation method thereof Technical Field The invention relates to the technical field of flushing liquid, in particular to a flushing liquid for sodium dipping treatment in an emergency environment of a sodium-related factory building and a preparation method thereof. Background In the prior art, aiming at different chemical contamination, there are various types of decontaminating agents, such as acid-base type decontaminating agents, including inorganic acids and organic acids of the acid decontaminating agents, alkaline solutions of the alkaline decontaminating agents which take water as a solvent, commonly known inorganic strong alkaline aqueous solutions of sodium hydroxide, potassium hydroxide and the like and inorganic weak alkaline aqueous solutions of sodium carbonate, sodium bicarbonate and the like, and alkaline nonaqueous disinfectants which take organic matters as solvents, such as alkali-alcohol-amine system disinfectants DS2 developed in the United states, 191 decontaminating agents developed in China and the like. The oxidative chlorination type decontaminating agents can be divided into active chlorine disinfectants and super (super) oxide disinfectants from the action mechanism of oxidative chlorination reaction. Such decontaminating agents produce low-or non-toxic redox products by undergoing redox reactions with the decontaminated product. The adsorption type decontaminating agent mainly comprises active clay, silica gel powder, high molecular adsorption resin and the like, and is mainly used for eliminating and disinfecting chemical poison liquid drops by removing chemical poison from the surface through physical adsorption. The adsorption type decontaminating agent has proper pore structure, surface structure and large specific surface area, and is generally free from chemical reaction with the adsorbate and the medium, and has strong selective adsorption capability. Catalytic type decontaminating agent, which can accelerate toxic chemical substances to generate nontoxic substances or low toxic substances under the action of catalyst by utilizing catalytic principle, can be divided into acid-base catalytic type decontaminating agent, biological (enzyme) catalytic type decontaminating agent and photocatalytic type decontaminating agent. The acid-base catalytic type decontaminating agent is a catalytic type decontaminating agent which is used in a large amount, such as metal oxides of alumina, titanium dioxide and the like, and can catalyze chemical poisons to undergo oxidation and disproportionation reactions so as to degrade the chemical poisons. The complex type decontaminating agent can be used for quickly combining various substances such as acid, alkali, reducing agent, oxidant, solvent and the like to generate chelation reaction, so that toxic substances are converted into non-toxic or low-toxic substances. The acid-base type decontaminating agent has strong corrosion and destruction effects and poor universality, can generate harmful byproducts when being used, has high storage and use requirements, has limited treatment capacity, has obvious difference on the treatment efficiency of different samples, and has severe reaction conditions and limitations. The complexing type decontaminating agent is paid attention to by virtue of the efficient complexing capability and the acid-base neutralization capability, and the efficient chemical burn site emergency rescue flushing liquid which is mainstream in the current market has the defects of high price, no domestic replacement of domestic like products and the like. Because of the active chemical nature of sodium, the sodium is easy to react with oxygen or water, and the factory building of the sodium-related process usually adopts a strict sealing design to prevent sodium leakage. At present, on-site emergency treatment for sodium contaminated personnel mainly uses clear water flushing under emergency conditions, but on-site clear water acquisition difficulty is high in a sodium-related workplace, and clear water flushing effect is limited. Therefore, development of a novel flushing fluid with the advantages of low toxicity, strong complexing force, large acid-base buffer capacity and low price is urgently needed, so that the novel flushing fluid is suitable for emergency decontamination treatment of people in a sodium-related factory environment. Disclosure of Invention Aiming at the defects of the prior art, the invention aims to provide a flushing fluid for sodium dipping treatment in an emergency environment of a sodium-related factory building and a preparation method thereof. The technical scheme adopted by the invention is as follows: The invention provides a flushing fluid for sodium dipping treatment in an emergency environment of a sodium-related factory building, which comprises the following components in percentag