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CN-122005653-A - Wine cistanche traditional Chinese medicine decoction piece and preparation method thereof

CN122005653ACN 122005653 ACN122005653 ACN 122005653ACN-122005653-A

Abstract

The application relates to the technical field of traditional Chinese medicine processing, and in particular discloses a cistanche deserticola traditional Chinese medicine decoction piece and a preparation method thereof. The preparation method of the cistanche deserticola traditional Chinese medicine decoction pieces comprises the following steps of pretreating cistanche deserticola, spreading, cooling to (-40) - (-30) DEG C at a cooling rate of 10-15 ℃ per minute, freezing for 7-9h, heating to (-6) - (-4) DEG C at a heating rate of 0.1-0.5 ℃ per minute, thawing for 7-9h, vacuumizing to a vacuum degree of (-0.07) - (-0.05) MPa, and under saturated steam pressure at a temperature of 60-80 ℃ for 10-20min, slicing, spreading for drying, moistening with yellow wine, spreading, steaming, spreading for drying, and obtaining the cistanche deserticola traditional Chinese medicine decoction pieces. The obtained cistanche deserticola traditional Chinese medicine decoction pieces have the total phenylethanoid glycoside content of more than 11mg/g, have higher medicine effect and meet market demands.

Inventors

  • Ding En
  • GUO YONGBIN
  • ZHAO HONGLEI
  • ZHANG XIAOCUI
  • LI WEI

Assignees

  • 河北睿济堂中药股份有限公司

Dates

Publication Date
20260512
Application Date
20260226

Claims (10)

  1. 1. A preparation method of a traditional Chinese medicine decoction piece of cistanche deserticola is characterized by comprising the following steps: s1, screening cistanche tubulosa, washing with water, and draining to obtain pretreated cistanche tubulosa; S2, spreading the pretreated cistanche salsa, cooling to (-40) - (-30) DEG C at a cooling rate of 10-15 ℃ per minute, freezing for 7-9h, heating to (-6) - (-4) DEG C at a heating rate of 0.1-0.5 ℃ per minute, thawing for 7-9h, vacuumizing to a vacuum degree of (-0.07) - (-0.05) MPa, and performing vacuum steam treatment under saturated steam pressure at a temperature of 60-80 ℃ for 10-20min to obtain softened cistanche salsa; S3, slicing the softened cistanche, spreading and drying to obtain cistanche slices; S4, mixing the cistanche deserticola slices with the yellow wine, moistening for 1-2 hours, spreading, steaming for 4-5 hours at the temperature of 100-110 ℃, spreading and drying to obtain the cistanche deserticola traditional Chinese medicine decoction pieces.
  2. 2. The method for preparing the cistanche tubulosa decoction pieces according to claim 1, wherein the water content of cistanche tubulosa is less than or equal to 10%.
  3. 3. The method for preparing the cistanche deserticola traditional Chinese medicine decoction pieces as claimed in claim 1, wherein in the step S2, the thickness of the spreading material is less than or equal to 6cm.
  4. 4. The method for preparing cistanche deserticola traditional Chinese medicine decoction pieces as claimed in claim 1, wherein in the step S3, the thickness of the cistanche deserticola tablet is 1-5mm.
  5. 5. The method for preparing the cistanche deserticola traditional Chinese medicine decoction pieces according to claim 1, wherein in the step S3, the thickness of the spreading material is less than or equal to 6cm in spreading material drying treatment, the temperature is 70-80 ℃, the time is 4-6h, and the spreading material is turned once every 0.5-1.5h in the spreading material drying process.
  6. 6. The preparation method of the cistanche deserticola traditional Chinese medicine decoction pieces as claimed in claim 1, wherein in the step S4, the weight ratio of cistanche deserticola slices to yellow wine is 100 (17-23).
  7. 7. The method for preparing the cistanche deserticola traditional Chinese medicine decoction pieces according to claim 1, wherein the alcoholic strength of the yellow wine is 12-20% vol.
  8. 8. The method for preparing the cistanche deserticola traditional Chinese medicine decoction pieces according to claim 1, wherein in the step S4, the thickness of the spreading material is less than or equal to 6cm in spreading material drying treatment, the temperature is 70-80 ℃, the time is 4-6h, and the spreading material is turned once every 0.5-1.5h in the spreading material drying process.
  9. 9. The method for preparing the cistanche deserticola traditional Chinese medicine decoction pieces as claimed in claim 1, wherein in the step S4, the thickness of the spreading material is less than or equal to 6cm.
  10. 10. The wine cistanche traditional Chinese medicine decoction piece is characterized in that the wine cistanche traditional Chinese medicine decoction piece is prepared by adopting the preparation method of the wine cistanche traditional Chinese medicine decoction piece according to any one of claims 1-9.

Description

Wine cistanche traditional Chinese medicine decoction piece and preparation method thereof Technical Field The application relates to the technical field of traditional Chinese medicine processing, in particular to a cistanche deserticola traditional Chinese medicine decoction piece and a preparation method thereof. Background Cistanche is a dry fleshy stem with scaly leaves of cistanche deserticola or cistanche tubulosa of Orobanchaceae, and has the effects of tonifying kidney yang, replenishing essence and blood, relaxing bowel and the like. In order to strengthen the actions of warming kidney and tonifying yang and alleviate the property of moistening intestines, wine-induced cistanche is used clinically. The preparation method of the cistanche deserticola traditional Chinese medicine decoction pieces mainly comprises the steps of screening cistanche deserticola, washing with water, draining, soaking in water, slicing, drying, moistening with yellow wine, steaming and drying. In actual processing, the applicant finds that the physical structure barrier of cistanche tubulosa is difficult to break effectively by adopting a water soaking mode, so that subsequent yellow wine is difficult to permeate fully, the dissolution and the thermal reaction are affected, the total phenylethanoid glycoside content of the cistanche tubulosa traditional Chinese medicine decoction pieces is about 9mg/g, the total phenylethanoid glycoside content is poor, and the cistanche tubulosa traditional Chinese medicine decoction pieces are required to be further improved. Disclosure of Invention The application provides a cistanche deserticola traditional Chinese medicine decoction piece and a preparation method thereof in order to improve the content of total phenylethanoid glycosides in the cistanche deserticola traditional Chinese medicine decoction piece. In a first aspect, the application provides a preparation method of a cistanche deserticola traditional Chinese medicine decoction piece, which adopts the following technical scheme: a preparation method of a traditional Chinese medicine decoction piece of cistanche deserticola comprises the following steps: s1, screening cistanche tubulosa, washing with water, and draining to obtain pretreated cistanche tubulosa; S2, spreading the pretreated cistanche salsa, cooling to (-40) - (-30) DEG C at a cooling rate of 10-15 ℃ per minute, freezing for 7-9h, heating to (-6) - (-4) DEG C at a heating rate of 0.1-0.5 ℃ per minute, thawing for 7-9h, vacuumizing to a vacuum degree of (-0.07) - (-0.05) MPa, and performing vacuum steam treatment under saturated steam pressure at a temperature of 60-80 ℃ for 10-20min to obtain softened cistanche salsa; S3, slicing the softened cistanche, spreading and drying to obtain cistanche slices; S4, mixing the cistanche deserticola slices with the yellow wine, moistening for 1-2 hours, spreading, steaming for 4-5 hours at the temperature of 100-110 ℃, spreading and drying to obtain the cistanche deserticola traditional Chinese medicine decoction pieces. The preparation method of the cistanche deserticola traditional Chinese medicine decoction pieces comprises the steps of firstly pretreating cistanche deserticola, then carrying out rapid cooling and freezing, slowly heating and thawing, vacuum steam softening, slicing, spreading and drying, moistening with yellow wine, steaming, spreading and drying to obtain the cistanche deserticola traditional Chinese medicine decoction pieces. Through the mutual coordination of rapid cooling and freezing, slow heating and thawing and vacuum steam softening, the total phenylethanoid glycoside content is more than 11mg/g, the color uniformity is (L value standard deviation) is more than 2, the higher drug effect and the color uniformity are shown, and the market demand is met. In rapid cryogenic freezing, a large number of fine ice crystals are instantaneously formed in the cell to pierce the cell membrane and the inner membrane. In slow temperature rise thawing, tiny and unstable intracellular ice crystals will melt first, and then the melted water recondenses on the still remaining larger ice crystals, which process is accompanied by increased ice crystal volume and morphological changes, generating continuous extrusion and expansion stresses from inside to the damaged cell walls, realizing inside-out deconstruction, wall breaking, and enhanced porosity and permeability. When the temperature is (-6) - (-4) DEG C, the cells are in a state of being spread by ice crystals, but the cell skeleton is not completely rebounded, namely, the cells are in a fragile state of semi-freezing and semi-thawing, at the moment, vacuum steam softening is carried out, the residual trace ice crystals are quickly sublimated by steam, the cells can be opened into micropores and combined with components such as cell walls, and the like, so that the cells are quickly and uniformly softened, conditions are provided for subsequent yellow wine d