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CN-122005683-A - Compound Baiqi pill and application thereof

CN122005683ACN 122005683 ACN122005683 ACN 122005683ACN-122005683-A

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a compound Baiqi pill and application thereof. The compound Baiqi pill is prepared from, by mass, 10-25 parts of phellodendron bark, 40-80 parts of hedysarum polybasic, 20-40 parts of rehmannia root and 10-30 parts of hawthorn leaf. The compound cypress astragalus pill takes hedysarum polybasic as a monarch drug, supplements qi and promotes diuresis, nourishes yin and promotes the production of body fluid, is matched with rehmannia to clear heat and cool blood, nourishes yin and promote the production of body fluid, and the phellodendron bark is used for clearing heat and drying dampness, purging pathogenic fire and removing steam, so that the effects of clearing heat and nourishing yin are more prominent, and the hawthorn leaves for regulating qi and activating blood circulation, removing blood stasis and dredging vessels, removing turbidity and reducing lipid are used together, so that the effects of clearing heat and removing dampness, removing blood stasis and reducing phlegm, and tonifying qi and nourishing yin are achieved, and the symptoms of patients with glycolipid metabolic syndrome can be effectively relieved, and the aim of treating both principal and secondary aspects of the disease is achieved.

Inventors

  • ZHANG MENGMENG
  • LI YAO
  • LI GENING
  • ZHANG NING
  • WANG SIWANG
  • HE JIGUANG
  • JI ZIYUN

Assignees

  • 杭州玖熙健康管理发展(集团)有限公司

Dates

Publication Date
20260512
Application Date
20260206

Claims (7)

  1. 1. The compound cypress astragalus pill is characterized by being prepared from, by mass, 10-25 parts of phellodendron, 40-80 parts of hedysarum polybasic, 20-40 parts of rehmannia and 10-30 parts of hawthorn leaves.
  2. 2. The compound Bai Qi pill according to claim 1, wherein the compound cypress astragalus pill is prepared from 20 parts of phellodendron, 60 parts of hedysarum polybasic, 30 parts of rehmannia and 20 parts of hawthorn leaves in parts by mass.
  3. 3. A method for preparing the compound cypress-astragalus pill according to claim 1 or 2, which is characterized by comprising the following steps: s1, taking two thirds of medicinal materials with the amount of 310 times of the prescription, adding clear water with the mass of 12 times, decocting for 3 times, 1 hour each time, combining filtrate, filtering, concentrating under reduced pressure, and spray drying to obtain dry paste powder; S2, taking the medicinal materials with the rest prescription amount, drying, crushing, and sieving with a 100-mesh sieve to obtain fine powder; s3, mixing the dry paste powder obtained in the step S1 with the fine powder obtained in the step S2, adding 60% ethanol, preparing pills by a molding method, and drying at 60 ℃ for 8 hours to obtain the compound cypress astragalus pill.
  4. 4. Use of the compound cypress-astragalus pill according to claim 1 or 2 in the preparation of a medicament for treating glycolipid metabolic syndrome.
  5. 5. The use of the compound cypress-astragalus pill according to claim 1 or 2 in the preparation of medicaments for reducing triglyceride TG and glutamic-oxaloacetic transaminase AST.
  6. 6. The use of the compound cypress-astragalus pill according to claim 1 or 2 in the preparation of a medicament for improving glutamic-pyruvic transaminase ALT.
  7. 7. Use of the compound cypress-astragalus pill according to claim 1 or 2 in the preparation of medicines for regulating total cholesterol TC.

Description

Compound Baiqi pill and application thereof Technical Field The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a compound Baiqi pill and application thereof. Background The metabolic syndrome (metabolic syndrome, MS) is a pathological state with insulin resistance as a core, which is a plurality of metabolic disorders such as blood pressure, blood sugar and blood fat. Since severe disorders and interactions of glycometabolism and lipid metabolism are the central pathological processes of MS, the concept of "glycolipid metabolism syndrome" can be more precisely summarized in its nature and has become a research hotspot for current metabolic diseases. Epidemiology showed that the incidence of glycolipid metabolic syndrome was 31% on average worldwide, and it was expected that by 2035, the incidence would increase to 53%. The clinical manifestations of the traditional Chinese medicine composition are mainly central obesity, hyperglycemia, hypertension, hypertriglyceridemia and the like, greatly aggravate the occurrence of diseases such as type II diabetes, nonalcoholic fatty liver, atherosclerosis and the like, and have the characteristics of high morbidity, high disability rate and high fatality rate. At present, the clinical treatment of the glycolipid metabolism syndrome mainly adopts strategies based on life style intervention (diet control and exercise enhancement) and combined with hypoglycemic lipid-regulating medicines such as metformin, atorvastatin and the like. However, in the field of traditional Chinese medicine, research has proved that natural active ingredients such as matrine, aloe anthraquinone and the like have good effects of reducing blood sugar and regulating lipid, but the ingredients are remained in the research stage at present, and are not successfully developed into mature traditional Chinese medicine preparations and are applied to clinic. The information disclosed in this background section is only for enhancement of understanding of the general background of the invention and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person of ordinary skill in the art. Disclosure of Invention The invention aims to provide a compound Baiqi pill and application thereof. In order to achieve the above purpose, the present invention provides the following technical solutions: the compound Baiqi pill is prepared from, by mass, 10-25 parts of phellodendron bark, 40-80 parts of hedysarum polybasic, 20-40 parts of rehmannia root and 10-30 parts of hawthorn leaf. Further, the compound cypress astragalus pill is prepared from the following components of 20 parts of amur corktree bark, 60 parts of hedysarum polybasic, 30 parts of rehmannia and 20 parts of hawthorn leaves by mass. The invention also provides a preparation method of the compound cypress-astragalus pill, which comprises the following steps: s1, taking two thirds of medicinal materials with the amount of 310 times of the prescription, adding clear water with the mass of 12 times, decocting for 3 times, 1 hour each time, combining filtrate, filtering, concentrating under reduced pressure, and spray drying to obtain dry paste powder; S2, taking the medicinal materials with the rest prescription amount, drying, crushing, and sieving with a 100-mesh sieve to obtain fine powder; s3, mixing the dry paste powder obtained in the step S1 with the fine powder obtained in the step S2, adding 60% ethanol, preparing pills by a molding method, and drying at 60 ℃ for 8 hours to obtain the compound cypress astragalus pill. The invention also provides application of the compound cypress-astragalus pill in preparing a medicament for treating glycolipid metabolic syndrome. The invention also provides application of the compound cypress-astragalus pill in preparing medicines for reducing triglyceride TG and glutamic-oxaloacetic transaminase AST. The invention also provides application of the compound cypress-astragalus pill in preparing medicines for improving glutamic-pyruvic transaminase ALT. The invention also provides application of the compound cypress-astragalus pill in preparing medicines for regulating total cholesterol TC. Compared with the prior art, the invention has the following beneficial effects: The compound cypress astragalus pill takes hedysarum polybasic as a monarch drug, supplements qi and promotes diuresis, nourishes yin and promotes the production of body fluid, is matched with rehmannia to clear heat and cool blood, nourishes yin and promote the production of body fluid, and the phellodendron bark is used for clearing heat and drying dampness, purging pathogenic fire and removing steam, so that the effects of clearing heat and nourishing yin are more prominent, and the hawthorn leaves for regulating qi and activating blood circulation, removing blood stasis and dredging vessels, removing turbidity an