CN-122005695-A - Compound extract with hair growth promoting function, and preparation method and application thereof

Abstract

The invention relates to a compound extract with a hair growth promoting function, a preparation method and application thereof. The compound extract is prepared from red date, astragalus root, chinese yam, poria cocos, sea buckthorn and medlar by extracting, concentrating and drying. The compound extract prepared by the invention can obviously reduce cavitation of hair follicles of mice, rarely or not see inflammatory infiltration and bleeding around hair follicle cells, obviously increase the number of new hair follicles and new/mature hair follicles in the skin area of the mice, promote hair follicle growth, and has obvious treatment effect on alopecia areata, and has the advantages of simple production process, prominent functions, small dosage, safe use, large-scale production and the like. Therefore, the method has wide application prospect in the aspects of developing medicaments and foods with the function of promoting hair growth.

Inventors

• Abrameti Iri
• NUERMAIMAITI.ABUDUKELIMU

Assignees

• 中国科学院新疆理化技术研究所

Dates

Publication Date

20260512

Application Date

20260408

Claims (5)

1. 1. A compound extract with a hair growth promoting function is characterized by being prepared from, by weight, 6-15 parts of red dates, 9-30 parts of astragalus mongholicus, 15-30 parts of Chinese yam, 10-15 parts of poria cocos, 3-10 parts of sea buckthorn and 6-12 parts of medlar.
2. 2. The compound extract with the hair growth promoting function according to claim 1, wherein the compound extract is prepared from 15 parts of red date, 12 parts of astragalus, 15 parts of Chinese yam, 10 parts of poria cocos, 3 parts of sea buckthorn and 9 parts of medlar by weight.
3. 3. A method for preparing a compound extract with hair growth promoting function according to claim 1, which is characterized by comprising the following steps: a. The extraction comprises weighing fructus Jujubae 6-15 parts, radix astragali 9-30 parts, rhizoma Dioscoreae 15-30 parts, poria 10-15 parts, fructus Hippophae 3-10 parts and fructus Lycii 6-12 parts, reflux treating with 80% ethanol for 1 time, filtering, discarding supernatant, decocting the residue with water-water ratio of 1:8-16 for 1-3 times, each time for 1-2 hours, filtering, and mixing the supernatants to obtain total extractive solution; b. concentrating, namely vacuum concentrating the total extract obtained in the step a at 50-60 ℃ to obtain a concentrated solution which is concentrated to 1/20-1/10 of the volume of the original total extract; c. And d, drying and crushing, namely vacuum drying the concentrated solution obtained in the step b at 50-60 ℃ and crushing to obtain the compound extract.
4. 4. The use of a compound extract having a hair growth promoting function according to claim 1 for the preparation of a hair growth promoting medicament.
5. 5. The use of a compound extract having a hair growth promoting function according to claim 1 for preparing a functional food for promoting hair growth.

Description

Compound extract with hair growth promoting function, and preparation method and application thereof Technical Field The invention belongs to the technical field of medicines and foods with a hair growth promoting function, and particularly relates to a compound extract with the hair growth promoting function, a preparation method and application thereof. Background The problem of hair loss has become a global health challenge, increasingly affecting people's quality of life and mental health. With the increase of the life rhythm and the increase of the environmental pressure in the modern society, the alopecia crowd presents a trend of younger, and the alopecia crowd is expanded to a wide age group including teenagers from the traditional middle-aged and elderly people. Studies have indicated that about 50% of men and 30% of women worldwide suffer from alopecia, with androgenic alopecia (AGA) and alopecia areata being the most common, and particular types of post partum alopecia, chemotherapy alopecia, etc. are also of increasing concern. Currently, alopecia is considered as a physiological problem, and is more developed into an important social and psychological issue, and patients often have sped, anxiety and other emotions caused by image damage, and even affect professional development and interpersonal relationship. This phenomenon has driven a rapid growth in the hair loss treatment market, and consumer demand for safe and effective solutions is urgent. Alopecia areata (alopecia areata, AA) is a sudden, non-scarring alopecia disease, which is a chronic inflammatory skin disease. The characteristics include the formation of circular or oval hair loss spots, the scalp being the most common affected part, the boundary being clear, the skin being smooth, free of inflammation, generally not painful or itchy, but other areas with hair may occur. Alopecia areata is generally considered to be an autoimmune disease, which is caused by the wrong attack on hair follicles by the immune system. In addition to immune factors, genetic, mental stress, endocrine dyscrasia, etc. may cause alopecia areata, but immune attack is currently the most prevalent explanation. Although the existing treatment methods have certain effects, the existing treatment methods have obvious limitations. The main stream means such as minoxidil and finasteride can delay the hair loss process, but the individual difference of the curative effect is large, partial patients may have side effects such as scalp irritation, sexual dysfunction and the like, and the patients are easy to relapse after stopping the drug. Although the hair-planting operation can directly improve the appearance, the cost is high, the trauma is large, and the root cause cannot be solved. In addition, the problem of safety of chemical synthetic drugs for long-term use is increasingly prominent, and consumers are prompted to switch to alternatives such as natural plant extracts. The traditional Chinese medicine compound has unique potential in the field of hair growth due to the advantages of multiple targets and low toxicity, but single components or simple combination are difficult to meet the complex pathological requirements, and the curative effect is urgently required to be improved through scientific compounding. Under the background, the development of novel compound extracts becomes an important break. The compound preparation can regulate hair follicle microenvironment, promote blood circulation and inhibit inflammatory factors simultaneously through a synergistic action mechanism, so that the hair growth cycle is comprehensively activated. For example, traditional medicinal materials such as ginseng, polygonum multiflorum and the like are rich in active ingredients such as saponin, polysaccharide and the like, can stimulate proliferation of papilla cells and prolong the growth period, and the biota orientalis leaf extract can protect hair follicles from damage through antioxidation. Modern researches prove that the multicomponent compound can obviously enhance the bioavailability, reduce the drug resistance risk and provide a safer and lasting solution for treating alopecia. Therefore, the systematic research of the compound extract with the function of promoting hair growth is not only helpful to fill the blank of the existing therapy, but also promotes the modernization of traditional Chinese medicine and meets the demands of global consumers on natural and efficient products. Disclosure of Invention The invention aims to provide a compound extract with a hair growth promoting function, a preparation method and application thereof. The compound extract is prepared from red date, astragalus root, chinese yam, poria cocos, sea buckthorn and medlar by extracting, concentrating and drying, and can be prepared into medicines and foods with the function of promoting hair growth. The compound extract prepared by the invention can obviously reduce cavitation of hair