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CN-122005709-A - Composition for relieving depression anxiety of patient treated by maintenance hemodialysis and application of composition

CN122005709ACN 122005709 ACN122005709 ACN 122005709ACN-122005709-A

Abstract

The invention provides a composition for relieving depression anxiety of a patient treated by maintenance hemodialysis and application thereof, and belongs to the technical field of traditional Chinese medicines. The composition comprises, by weight, 25-35 parts of astragalus membranaceus, 10-20 parts of rhizoma polygonati, 10-20 parts of radix puerariae, 5-15 parts of ligusticum wallichii, 10-20 parts of rhizoma dioscoreae septemlobae, 25-35 parts of radix salviae miltiorrhizae, 8-18 parts of angelica sinensis, 5-15 parts of prepared aconite root, 8-18 parts of stiff silkworm, 25-35 parts of herba violae, 10-20 parts of poria cocos and 8-18 parts of bighead atractylodes rhizome. The invention achieves the purposes of organism balance, eliminating evil and regulating spirit by coordinating viscera balance through the synergistic cooperation of the components and the combined treatment of the components, has obvious curative effects on reducing the clinical traditional Chinese medicine syndrome integral of patients, reducing anxiety integral and improving the level of inflammatory factors, and has obvious effects on relieving discomfort of the patients, relieving anxiety state and relieving inflammatory response in the organism.

Inventors

  • Yi Xuanwei
  • CEN JIE
  • HUANG ZHEN

Assignees

  • 上海市闵行区中西医结合医院(上海市闵行区结核病防治院)

Dates

Publication Date
20260512
Application Date
20260316

Claims (8)

  1. 1. The composition for relieving the depression anxiety of the patient subjected to the maintenance hemodialysis treatment is characterized by comprising, by weight, 25-35 parts of astragalus membranaceus, 10-20 parts of rhizoma polygonati, 10-20 parts of radix puerariae, 5-15 parts of ligusticum wallichii, 10-20 parts of yam rhizome, 25-35 parts of radix salviae miltiorrhizae, 8-18 parts of angelica sinensis, 5-15 parts of radix aconiti lateralis preparata, 8-18 parts of stiff silkworm, 25-35 parts of herba violae, 10-20 parts of poria cocos and 8-18 parts of bighead atractylodes rhizome.
  2. 2. The composition of claim 1, which is characterized by comprising, by weight, 28-32 parts of astragalus membranaceus, 12-18 parts of rhizoma polygonati, 12-18 parts of radix puerariae, 8-12 parts of ligusticum wallichii, 12-18 parts of yam rhizome, 28-32 parts of radix salviae miltiorrhizae, 10-15 parts of angelica sinensis, 8-12 parts of prepared aconite, 10-15 parts of stiff silkworm, 28-32 parts of herba violae, 12-18 parts of poria cocos and 10-15 parts of bighead atractylodes rhizome.
  3. 3. The composition of claim 1, which is characterized by comprising the following components, by weight, 30 parts of astragalus membranaceus, 15 parts of rhizoma polygonati, 15 parts of radix puerariae, 10 parts of ligusticum wallichii, 15 parts of rhizoma dioscoreae septemlobae, 30 parts of radix salviae miltiorrhizae, 12 parts of angelica sinensis, 9 parts of radix aconiti lateralis preparata, 12 parts of stiff silkworm, 30 parts of herba violae, 15 parts of poria cocos and 12 parts of bighead atractylodes rhizome.
  4. 4. The preparation method of the composition according to any one of claims 1-3, which is characterized in that the preparation method comprises the steps of weighing prepared aconite, decocting for 30-60 min, adding other components, continuously decocting for 1-3 times, filtering, collecting and combining liquid medicine to obtain the composition.
  5. 5. The preparation method according to claim 4, wherein the amount of water used in the decoction of the prepared aconite root is 2-4 times of the total mass of all the components.
  6. 6. The preparation method according to claim 4, wherein the time for continuing the decoction is 20-40 min/time, and the temperature for continuing the decoction is 90-100 ℃.
  7. 7. The method according to claim 4, wherein the number of the screen meshes for the filtration is 80 to 120 mesh.
  8. 8. Use of a composition according to any one of claims 1 to 3 or obtained by a method according to any one of claims 4 to 9 for the preparation of a formulation for the treatment of depression anxiety.

Description

Composition for relieving depression anxiety of patient treated by maintenance hemodialysis and application of composition Technical Field The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a composition for relieving depression anxiety of a patient treated by maintenance hemodialysis and application thereof. Background The end-stage renal failure uremic phase is a renal failure decompensated disease that develops from one or more renal or other visceral diseases. Metabolic diseases, mainly diabetes and hypertension, are becoming the major factors causing contemporary Chronic kidney disease (Chronic KIDNEY DISEASE, CKD) and ultimately leading to end-stage renal failure. The maintenance hemodialysis treatment (MAINTENANCE HEMODIALYSIS, MHD) of patients with chronic renal failure uremia is a vital method for the life maintenance and continuation of CKD end-stage patients. Studies have shown that nearly 40.2% of MHD patients present with varying degrees of anxiety and depression that are detrimental to the patients' disease after cure and prognosis. Therefore, research on a medicament capable of realizing the intervention of the emotion of a patient and timely relieving the depression anxiety state of the patient so as to improve long-term prognosis and prognosis is imperative. Disclosure of Invention Accordingly, the present invention is directed to a composition for alleviating depression anxiety in patients undergoing maintenance hemodialysis and its use. The invention has the function of resolving depression through reasonable formula and combined use with the Qin needle, so as to improve anxiety and depression states of patients, and discusses evaluation of the influence of the traditional Chinese medicine combined external treatment method on the emotion of the patients with scientific and strict attitude, thereby providing a foundation for continuously and deeply researching psychological rehabilitation of the traditional Chinese medicine in MHD patients. In order to achieve the above object, the present invention provides the following technical solutions: The invention provides a composition for relieving depression anxiety of a patient subjected to maintenance hemodialysis treatment, which comprises, by weight, 25-35 parts of astragalus membranaceus, 10-20 parts of rhizoma polygonati, 10-20 parts of radix puerariae, 5-15 parts of ligusticum wallichii, 10-20 parts of yam rhizome, 25-35 parts of radix salviae miltiorrhizae, 8-18 parts of angelica sinensis, 5-15 parts of prepared aconite root, 8-18 parts of stiff silkworm, 25-35 parts of herba violae, 10-20 parts of poria cocos and 8-18 parts of bighead atractylodes rhizome. The traditional Chinese medicine composition is characterized by comprising, by weight, 28-32 parts of astragalus membranaceus, 12-18 parts of rhizoma polygonati, 12-18 parts of radix puerariae, 8-12 parts of ligusticum wallichii, 12-18 parts of rhizoma dioscoreae, 28-32 parts of radix salviae miltiorrhizae, 10-15 parts of Chinese angelica, 8-12 parts of prepared aconite root, 10-15 parts of stiff silkworm, 28-32 parts of herba violae, 12-18 parts of poria cocos and 10-15 parts of bighead atractylodes rhizome. Preferably, the Chinese medicinal composition comprises, by weight, 30 parts of astragalus membranaceus, 15 parts of rhizoma polygonati, 15 parts of radix puerariae, 10 parts of ligusticum wallichii, 15 parts of yam rhizome, 30 parts of radix salviae miltiorrhizae, 12 parts of angelica sinensis, 9 parts of radix aconiti lateralis preparata, 12 parts of stiff silkworm, 30 parts of herba violae, 15 parts of poria cocos and 12 parts of bighead atractylodes rhizome. The invention provides a preparation method of a composition, which comprises the steps of weighing prepared aconite, decocting for 30-60 min, adding other components, continuously decocting for 1-3 times, filtering, collecting and combining liquid medicine to obtain the composition. Preferably, the water consumption for decocting the prepared aconite root is 2-4 times of the total mass of all the components. Preferably, the time for continuous decoction is 20-40 min/time, and the temperature for continuous decoction is 90-100 ℃. Preferably, the number of the screen meshes of the filtering is 80-120 meshes. The invention also provides application of the composition or the composition obtained according to the preparation method in preparation of a preparation for treating depression anxiety. Compared with the prior art, the composition for relieving depression anxiety of patients treated by maintenance hemodialysis and the application thereof have the following beneficial effects. The prepared aconite and astragalus are monarch, kidney warming and yang supporting, qi tonifying and meridian dredging, the rhizoma polygonati and the kudzuvine root are ministerial, the kidney nourishing and essence tonifying are performed, the main pathogenesis of kidney yang deficien