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CN-122005727-A - Weight-losing traditional Chinese medicine tincture based on nanotechnology and magnetized magnetic stirring and preparation method thereof

CN122005727ACN 122005727 ACN122005727 ACN 122005727ACN-122005727-A

Abstract

A weight-losing traditional Chinese medicine tincture based on nanotechnology and magnetization magnetic stirring and a preparation method thereof belong to the technical field of traditional Chinese medicine preparations. The invention solves the problems of low dissolution rate of active ingredients, poor transdermal absorption, rough preparation process and the like of the traditional Chinese medicine weight-losing preparation. The tincture is prepared by carrying out nano-level refinement on raw materials such as lotus leaves, ginseng, astragalus roots, pseudo-ginseng, red sage roots, hawthorns, medicated leaven, malt, sophora fruits, dried rehmannia roots, tortoise plastron and the like within five years after artificial planting, adopting 50% -75% ethanol solution, extracting for 2-6 hours at 20-40 ℃ in a 1000-5000 GS magnetized magnetic stirring device, and then filtering, concentrating and purifying. The invention obviously improves the dissolution rate and transdermal absorption rate of the active ingredients by the synergistic technology of nano refinement and magnetization extraction, realizes the effects of enhancing transdermal absorption, accelerating lipolysis and improving in vivo metabolism, and is suitable for simple obese people. The method has the advantages of stable process, mild conditions, convenience for industrial production and good popularization and application prospects.

Inventors

  • MA GUOLIANG

Assignees

  • 马国梁

Dates

Publication Date
20260512
Application Date
20260303

Claims (8)

  1. 1. The weight-reducing traditional Chinese medicine tincture based on nano technology and magnetic stirring is characterized by being prepared from, by weight, 10-30 parts of lotus leaves, 10-25 parts of ginseng (within five years of artificial planting), 10-20 parts of astragalus mongholicus, 5-15 parts of pseudo-ginseng, 5-15 parts of red-rooted salvia root, 3-10 parts of hawthorn, 3-10 parts of medicated leaven, 3-10 parts of malt, 3-10 parts of sophora fruit, 3-10 parts of dried rehmannia root, 3-10 parts of tortoise plastron, 40-60 parts of ethanol solution and a traditional Chinese medicine active ingredient subjected to nano-level refining and magnetization treatment, wherein the tincture is subjected to full mixing, extraction and homogenization treatment by adopting the magnetic stirring technology in the preparation process.
  2. 2. The weight-reducing traditional Chinese medicine tincture according to claim 1, wherein the volume concentration of the ethanol solution is 50% -75%.
  3. 3. The weight-reducing traditional Chinese medicine tincture according to claim 1, wherein the particle size range of the traditional Chinese medicine raw materials after the nanometer level refining treatment is 100-800 nm.
  4. 4. The weight-reducing traditional Chinese medicine tincture according to claim 1, wherein the magnetization treatment is carried out by magnetic stirring by a magnetization device with a magnetic field strength of 1000-5000 gs.
  5. 5. The weight-reducing traditional Chinese medicine tincture according to claim 1, wherein the tincture has the effects of enhancing transdermal absorption, accelerating lipolysis and improving in-vivo metabolism.
  6. 6. The preparation method of the weight-losing traditional Chinese medicine tincture based on the nano technology and the magnetization magnetic stirring is characterized by comprising the following steps of: (1) Weighing folium Nelumbinis, ginseng radix (planted within five years), radix astragali, notoginseng radix, saviae Miltiorrhizae radix, fructus crataegi, massa Medicata Fermentata, fructus Hordei Germinatus, fructus Sophorae, radix rehmanniae and carapax et Plastrum Testudinis in proportion, cleaning, and drying; (2) Superfine pulverizing the dried Chinese medicinal materials to nanometer particle size; (3) Adding the nano-scale traditional Chinese medicine powder into ethanol solution, and placing the ethanol solution into a magnetization magnetic stirring device for low-temperature stirring extraction; (4) Filtering, standing, concentrating and purifying after extraction is completed, and preparing the weight-losing traditional Chinese medicine tincture.
  7. 7. The method according to claim 6, wherein the time of the magnetizing magnetic stirring is 2-6 hours, and the temperature is controlled to be 20-40 ℃.
  8. 8. The method according to claim 6, wherein the nano-sized powder of the Chinese medicine is capable of improving the dissolution rate and transdermal absorption rate of the active ingredient of the Chinese medicine.

Description

Weight-losing traditional Chinese medicine tincture based on nanotechnology and magnetized magnetic stirring and preparation method thereof Technical Field The invention belongs to the technical field of traditional Chinese medicine preparations, in particular relates to a weight-losing traditional Chinese medicine tincture, and especially relates to a weight-losing traditional Chinese medicine tincture prepared based on a nanometer refining technology and a magnetizing magnetic stirring technology and a preparation method thereof. Background At present, the traditional Chinese medicine weight-losing preparation mostly adopts common crushing, water decoction or conventional ethanol extraction process, and has the problems of low dissolution rate of active ingredients, poor absorption and utilization rate, insufficient uniformity of the preparation, slow onset of action and the like. Meanwhile, the conventional extraction method is not combined with nano refinement and magnetic field activation treatment, so that efficient release and transdermal absorption of active ingredients are difficult to realize, and the requirements of modern people on safe, efficient and rapid weight-losing products cannot be met. Therefore, the invention provides the weight-losing traditional Chinese medicine tincture through the synergistic effect of nano-scale refinement and magnetization magnetic stirring, which effectively improves the dissolution rate, transdermal absorption rate and bioavailability of components, and achieves the effects of accelerating fat decomposition and improving organism metabolism. Disclosure of Invention The invention aims to overcome the defects of the prior art and provide a weight-losing traditional Chinese medicine tincture based on nano technology and magnetization magnetic stirring, which has the characteristics of high component dissolution, quick absorption, obvious metabolism improvement, fat decomposition acceleration and the like. The invention also aims to provide a preparation method of the weight-losing traditional Chinese medicine tincture, which has stable process and strong controllability and is suitable for industrial production. In order to achieve the above purpose, the invention adopts the following technical scheme: 1. Weight-reducing Chinese medicinal tincture composition A weight-losing traditional Chinese medicine tincture based on nanotechnology and magnetization magnetic stirring is prepared from the following raw materials in parts by weight: 10-30 parts of lotus leaves, 10-25 parts of ginseng within five years of artificial planting, 10-20 parts of astragalus mongholicus, 5-15 parts of pseudo-ginseng, 5-15 parts of radix salviae miltiorrhizae, 3-10 parts of hawthorns, 3-10 parts of medicated leaven, 3-10 parts of malt, 3-10 parts of sophora fruit, 3-10 parts of radix rehmanniae, 3-10 parts of tortoise plastron and 40-60 parts of ethanol solution; The traditional Chinese medicine raw materials are subjected to nano-level refining treatment and magnetization treatment; the tincture is prepared by adopting a magnetizing magnetic stirring technology to perform full mixing, extraction and homogenization treatment. Further, the volume concentration of the ethanol solution is 50% -75%. Further, the grain size range of the traditional Chinese medicine raw materials after the nano-level refining treatment is 100-800 nanometers. Further, the magnetization treatment adopts a magnetization device with the magnetization intensity of 1000-5000 GS to carry out magnetic stirring. Further, the tincture has the effects of enhancing transdermal absorption, accelerating lipolysis and improving in vivo metabolism. 2. Preparation method of weight-losing traditional Chinese medicine tincture A preparation method of a weight-losing traditional Chinese medicine tincture based on nanotechnology and magnetization magnetic stirring comprises the following steps: (1) Weighing folium Nelumbinis, radix Ginseng, radix astragali, radix Notoginseng, radix Salviae Miltiorrhizae, fructus crataegi, massa Medicata Fermentata, fructus Hordei Germinatus, fructus Sophorae, radix rehmanniae, and carapax et Plastrum Testudinis, cleaning, and drying; (2) Superfine pulverizing the dried Chinese medicinal materials to nanometer particle size; (3) Adding the nano-scale traditional Chinese medicine powder into ethanol solution, and placing the ethanol solution into a magnetization magnetic stirring device for low-temperature stirring extraction; (4) Filtering, concentrating and purifying after extraction is completed, and preparing the weight-losing traditional Chinese medicine tincture. Further, the magnetizing magnetic stirring time is 2-6 hours, and the temperature is controlled at 20-40 ℃. Further, the nano-scale traditional Chinese medicine powder can improve the dissolution rate and transdermal absorption rate of the effective components of the traditional Chinese medicine. Advantageous effects Compared with the