CN-122005734-A - Traditional Chinese medicine composition for relieving and treating female dysmenorrhea

Abstract

The invention relates to the field of medicines, in particular to a traditional Chinese medicine composition for relieving and treating female dysmenorrhea and application thereof. The composition disclosed by the invention consists of medicinal materials for activating blood, promoting qi circulation, regulating qi, promoting diuresis and removing dampness. The composition disclosed by the invention is prepared by three methods of activating blood, promoting qi circulation and promoting diuresis, and can be used for systematically improving painful diseases caused by qi stagnation and blood stasis and dampness on the premise of ensuring safety, and has the advantages of definite action mechanism, stable curative effect, high safety, wide application range and the like.

Inventors

• Fu Liuhong
• LV SHAOLI
• FU QINGXIA
• LOU ZHAO

Assignees

• 杭州归正健康科技有限责任公司

Dates

Publication Date

20260512

Application Date

20260310

Claims (10)

1. 1. A Chinese medicinal composition for relieving and treating female dysmenorrhea consists of 20.3 parts of blood-activating medicinal materials, 6.7 parts of qi-flowing regulating medicinal materials and 4.0 parts of dampness-excreting and dampness-excreting medicinal materials in parts by mass; Wherein said steps are as follows: The blood-activating medicines comprise radix Angelicae sinensis, curcuma rhizome, rhizoma Ligustici Chuanxiong, radix Paeoniae Rubra, and fructus crataegi, The qi-promoting and qi-regulating herbs include rhizoma Cyperi and fructus Amomi, The dampness-excreting and dampness-excreting herbs are Poria cocos and alisma orientale.
2. 2. A composition comprises radix Angelicae sinensis, rhizoma Curcumae Longae, rhizoma Chuanxiong, fructus crataegi, radix Paeoniae Rubra, rhizoma Cyperi, fructus Amomi, poria, and rhizoma Alismatis.
3. 3. The composition according to claim 2, according to the mass portion of the components, 1.0 Part of Chinese angelica root, and the like, 3.5 To 4.5 parts, preferably 4.0 parts, Ligusticum wallichii 2.0-3.5 parts, preferably 2.7 parts, From 7.0 to 8.5 parts, preferably 7.7 parts, 4.5 To 5.5 parts, preferably 5.0 parts, 3.5 To 4.5 parts, preferably 4.0 parts, Fructus Amomi 2.0-3.5 parts, preferably 2.7 parts, Poria cocos 1.0-1.5 parts, preferably 1.3 parts, 2.0-3.5 Parts of alisma orientale, preferably 2.7 parts.
4. 4. A composition according to claim 3, according to the mass portion of the components, 1.0 Part of Chinese angelica root, and the like, 4.0 Parts of turmeric, wherein the turmeric comprises, 2.7 Parts of szechuan lovage rhizome, 7.7 Parts of red paeony root, 5.0 Parts of hawthorn fruit, 4.0 Parts of nutgrass galingale rhizome, 2.7 Parts of fructus amomi and the like, 1.3 Parts of poria cocos wolf, 2.7 Parts of alisma orientale.
5. 5. An oral formulation prepared from the composition of any one of claims 1-4.
6. 6. The oral formulation of claim 5, which may contain a pharmaceutically acceptable carrier.
7. 7. The oral preparation of claim 5, which can be pill, tablet, capsule, granule, suspension, powder or oral liquid.
8. 8. A method for preparing the composition according to any one of claims 1 to 4, wherein the medicinal materials are mixed uniformly and pulverized and passed through 80 mesh.
9. 9. Use of a composition according to any one of claims 1 to 4 or an oral formulation according to any one of claims 5 to 7 for the preparation of a product for the alleviation and treatment of female dysmenorrhoea.
10. 10. The use according to claim 9 for alleviating or treating dysmenorrhea caused by one or more of body cold and blood stasis, qi stagnation and blood stasis, downward flow of damp-heat or cold-damp stagnation.

Description

Traditional Chinese medicine composition for relieving and treating female dysmenorrhea Technical Field The invention relates to the field of medicines, in particular to a traditional Chinese medicine composition for relieving and treating female dysmenorrhea and application thereof. Background The occurrence of contemporary female dysmenorrhea (dysmenorrhea) has increased significantly and has become a common problem affecting quality of life. Busy work rhythm, mental stress, lack of exercise for sedentary sitting, irregular diet and work and rest, and causes many women to develop originally mild physiological pain into intractable dysmenorrhea which is difficult to relapse. Clinically, the traditional Chinese medicine composition is characterized by lower abdomen pain and distending pain, and is more often accompanied with systemic reactions such as hypodynamia, mood swings, headache, nausea and the like, and serious people even influence daily study and work. Dysmenorrhea is characterized by younger age, diversified symptoms and prolonged duration, reflects new challenges facing modern women in terms of lifestyle and health management, and also prompts society to pay more attention and support. According to a number of high quality epidemiological studies worldwide, dysmenorrhea (dysmenorrhea) is one of the most common female reproductive health problems, with global prevalence generally at a high level. According to the system review "Prevalence of Dysmenorrhea and Its Impact on Women's Life. BMC Womens Health. 2022 Jul 4;22:270., PMC9254498", published in Journal of PAIN RESEARCH, the overall prevalence of dysmenorrhea is approximately between 45% and 95% worldwide, and has a significant impact on women's learning ability, work efficiency and mental state. This review also indicates that dysmenorrhea has a particularly pronounced effect on teenagers and young women, constituting a significant public health burden worldwide. Research emphasizes that the primary dysmenorrhea proportion of Chinese females is high, and the problems of limited daily activities, mood swings, reduced quality of life and the like are often accompanied. Along with the influence of life style factors such as rising academic pressure, accelerating life rhythm, sedentary hypokinesia and the like, dysmenorrhea presents a remarkable younger trend, and is more common among middle school students and college students. In addition, several systematic reviews indicate that dysmenorrhea occurs in close association with early menstrual onset, family history, irregular menstruation, emotional stress, and sleep insufficiency (PREVALENCE OF DYSMENORRHEA AND ITS IMPACT on work's Life). These factors are superimposed in different groups, so that dysmenorrhea presents a complex modern etiology structure, and improvement and solution through rational medication are needed. In general, current research has consistently shown that dysmenorrhea has become an important public health issue affecting global and chinese female health, with both high-volatility and younger trends not being ignored. With changes in lifestyle, increased learning and working pressures, and increased awareness of female health, diagnosis, intervention, and management of dysmenorrhea are receiving increasing attention. In the future, improving the burden of dysmenorrhea and improving the overall reproductive health of women is an urgent problem to be solved. In the traditional Chinese medicine, the causes of dysmenorrhea comprise five aspects of body cold and blood stasis (also called cold-dampness stagnation), qi stagnation and blood stasis, qi and blood deficiency, damp-heat downward flow and kidney deficiency. When the nutrition supply is sufficient, deficiency of qi and blood and kidney deficiency are rarely the cause of dysmenorrhea of the current generation, and cold body and blood stasis caused by lack of exercise, qi stagnation and blood stasis caused by high pressure in life and study, and damp-heat downward flow caused by improper diet are three main causes of dysmenorrhea of women, and are representative Chinese patent medicines. Representative medicine and formula for treating three major dysmenorrheal The representative drugs corresponding to the three causes have singleness and limitation. Among them, shaoyuan Zhu Yu Wan and ai Fu Qing Gong Wan are better at warming channel and dispelling cold and activating blood and resolving stasis, but do not consider resolving and discharging damp-heat. Under the conditions of cold body and qi stagnation, the metabolic efficiency of female lower body is inevitably greatly slowed down, and damp-heat is formed for a long time. Without resolving and discharging damp-heat, pure warming channels and activating blood is most likely to cause dryness-heat mismatching. The Xiaoyao pill is more important than the qi-moving and cassia twig-poria pills in activating blood and both have the effect of promoting blood circulation, but th