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CN-122005737-A - Traditional Chinese medicine for treating vitiligo and preparation method thereof

CN122005737ACN 122005737 ACN122005737 ACN 122005737ACN-122005737-A

Abstract

The invention discloses a traditional Chinese medicine for treating vitiligo and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. Comprises oral medicine, including radix astragali, radix Codonopsis, atractylodis rhizoma, rhizoma Smilacis Glabrae, rhizoma Dioscoreae, fructus Psoraleae, radix Angelicae sinensis, cornu Bubali, corni fructus, saviae Miltiorrhizae radix, radix Paeoniae Rubra, carthami flos, rhizoma Ligustici Chuanxiong, semen Persicae, polygoni Multiflori radix, ecliptae herba, cortex Mori, radix Saposhnikoviae, bupleuri radix, scutellariae radix, radix Curcumae, fructus Citri Sarcodactylis, rhizoma Cyperi, radix Gentianae, parched radix Paeoniae alba, fructus Atriplicis Sibiricae, fructus Gardeniae, radix Angelicae Dahuricae, rhizoma Typhonii. Also comprises topical extract of fructus Psoraleae, radix Angelicae Dahuricae, cortex Dictamni Radicis, polygoni Multiflori radix, borax, rhizoma Typhonii, semen Cuscutae, carthami flos, and Chinese liquor. The invention can regulate qi and blood, tonify liver and kidney, dredge channels and collaterals, strengthen root, promote pigment by external application, and treat both principal and secondary aspects of disease by combining internal and external application, and is especially suitable for middle-aged and elderly patients with qi and blood deficiency, liver and kidney deficiency, qi stagnation and blood stasis type vitiligo.

Inventors

  • WEN FEI

Assignees

  • 温飞

Dates

Publication Date
20260512
Application Date
20260403

Claims (8)

  1. 1. The traditional Chinese medicine for treating the vitiligo is characterized by comprising, by weight, 10-20 parts of astragalus membranaceus, 8-16 parts of codonopsis pilosula, 8-16 parts of bighead atractylodes rhizome, 15-25 parts of glabrous greenbrier rhizome, 10-20 parts of Chinese yam, 10-20 parts of fructus psoraleae, 8-16 parts of Chinese angelica, 10-20 parts of cornu bubali, 8-16 parts of dogwood, 10-20 parts of radix salviae miltiorrhizae, 8-16 parts of red paeony root, 6-14 parts of safflower, 6-14 parts of ligusticum wallichii, 6-14 parts of peach kernel, 10-20 parts of polygonum multiflorum, 10-20 parts of eclipta alba, 8-16 parts of cortex mori radicis, 6-14 parts of radix sileris, 6-14 parts of radix bupleuri, 6-14 parts of radix scutellariae, 6-14 parts of radix curcumae, 6-14 parts of fingered citron, 6-14 parts of rhizoma cyperi, 3-9 parts of gentian, 10-20 parts of fried white paeony root, 10-20 parts of white tribulus terrestris, 6-14 parts of fructus gardeniae, 6-14 parts of radix angelicae and 3-9 parts of rhizoma typhonii.
  2. 2. The traditional Chinese medicine for treating vitiligo according to claim 1, wherein the raw materials of the oral medicine comprise, by weight, 15 parts of astragalus membranaceus, 12 parts of codonopsis pilosula, 12 parts of bighead atractylodes rhizome, 20 parts of rhizoma smilacis glabrae, 15 parts of Chinese yam, 15 parts of fructus psoraleae, 12 parts of angelica sinensis, 15 parts of cornu bubali, 12 parts of dogwood, 15 parts of radix salviae miltiorrhizae, 12 parts of radix paeoniae rubra, 10 parts of safflower, 10 parts of ligusticum wallichii, 10 parts of peach kernel, 15 parts of polygonum multiflorum, 15 parts of eclipta alba, 12 parts of cortex mori radicis, 10 parts of radix saposhnikoviae, 10 parts of radix bupleuri, 10 parts of radix scutellariae, 10 parts of radix curcumae, 10 parts of fingered citron, 10 parts of rhizoma cyperi, 6 parts of gentian, 15 parts of stir-fried radix paeoniae alba, 15 parts of tribulus terrestris, 10 parts of gardenia, 10 parts of radix angelicae and 6 parts of rhizoma typhonii.
  3. 3. The traditional Chinese medicine for treating vitiligo according to claim 1, which is characterized by further comprising an external immersion liquid, wherein the external immersion liquid comprises, by weight, 20-40 parts of fructus psoraleae, 15-25 parts of radix angelicae, 15-25 parts of cortex dictamni, 15-25 parts of polygonum multiflorum, 3-9 parts of borax, 3-9 parts of rhizoma typhonii, 15-25 parts of semen cuscutae, 10-20 parts of safflower and 800-1200 parts of white spirit.
  4. 4. The traditional Chinese medicine for treating vitiligo according to claim 3, wherein the raw materials of the external infusion comprise, by weight, 30 parts of fructus psoraleae, 20 parts of radix angelicae, 20 parts of cortex dictamni, 20 parts of polygonum multiflorum, 6 parts of borax, 6 parts of rhizoma typhonii, 20 parts of semen cuscutae, 15 parts of safflower and 1000 parts of white spirit.
  5. 5. The traditional Chinese medicine for treating vitiligo according to claim 3, wherein the white spirit is 50-60 degrees edible grain white spirit.
  6. 6. The method for preparing a traditional Chinese medicine for treating vitiligo according to claim 3, wherein the preparation steps of the oral medicine are as follows: ① Weighing the raw materials according to the weight of the formula, removing impurities, cleaning and airing; ② Adding clear water for soaking; ③ Boiling with strong fire, continuously decocting with small fire for 25-30 minutes, and filtering to obtain a first medicinal liquid; ④ Adding clear water into the dregs again, boiling with strong fire, decocting with slow fire for 20-30 minutes, and filtering to obtain a second medicinal liquid; ⑤ Mixing the two filtrates to obtain Chinese medicinal decoction for oral administration; The preparation method of the external immersion liquid comprises the following steps: (1) Removing impurities from the raw materials, cleaning with clear water, air drying, pulverizing, and grinding borax into fine powder; (2) Placing the crushed medicinal materials and borax fine powder together into a sterile light-proof glass bottle, and adding 50-60 degrees white spirit to enable the liquid level to completely submerge the medicinal materials; (3) Sealing the bottle mouth, and soaking in a cool and ventilated place; (4) Filtering with double layers of sterile gauze after soaking, discarding residues, packaging the filtrate in sterile light-resistant bottle, and sealing and preserving to obtain the topical infusion.
  7. 7. The method for preparing a traditional Chinese medicine for treating vitiligo according to claim 6, wherein in the step (1) of preparing the external immersion liquid, all raw medicinal materials are crushed to have a particle size of 0.5-1 cm.
  8. 8. The method for preparing a Chinese medicine for treating vitiligo according to claim 6, wherein the step (2) of preparing the externally used infusion is carried out by soaking for 15 days, and shaking for 1 time every 2 days.

Description

Traditional Chinese medicine for treating vitiligo and preparation method thereof Technical Field The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine for treating vitiligo and a preparation method thereof. Background Vitiligo, also known as vitiligo and white spider, is a common multiple, acquired and idiopathic skin depigmentation disease. Clinically, white spots with different sizes and different forms appear on the skin, the boundary is clear, and the hair at the white spot part can be whitened to be mainly expressed, so that the appearance and the psychological health of a patient are seriously influenced. The disease can occur in various age groups, wherein the middle-aged and elderly people have higher disease probability due to the characteristics of body functions of the middle-aged and elderly people, deficiency of qi and blood, deficiency of liver and kidney, qi stagnation and blood stasis and the like, and the disease course is longer, the disease condition is easy to repeat, and the treatment difficulty is far higher than that of young patients. At present, most of the medicines for clinically treating the leucoderma are singly taken or singly and externally used, and obvious limitations exist that the singly taken medicine mainly regulates viscera and tonifies qi and blood, but the medicine reaches the local concentration of white spots, the effect is slow, long-term taking is often needed to see the effect, the gastrointestinal burden can be increased, the digestion function of middle-aged and elderly patients is not adapted, the singly taken medicine mainly stimulates the melanin generation locally, the local pigment change can be seen in a short period, the constitution of the patients cannot be radically improved, the illness state is easy to relapse, the irritation of part of the medicine is strong, the skin of the middle-aged and elderly patients is sensitive, and the allergic reaction is easy to occur. In addition, the formulation of the existing vitiligo treatment medicine is not optimized aiming at the physique characteristics of middle-aged and elderly patients, and the core pathogenesis of qi and blood deficiency, liver and kidney deficiency and qi stagnation and blood stasis of the middle-aged and elderly patients is ignored, so that the medicine suitability is poor and the treatment effect is poor. Therefore, research and development of a traditional Chinese medicine composition for treating vitiligo, which is suitable for the constitution of middle-aged and elderly patients, treats both principal and secondary aspects of disease and has stable curative effect and difficult recurrence, becomes a technical problem to be solved urgently in the current traditional Chinese medicine field. Disclosure of Invention The invention aims at solving the technical defects of slow curative effect and easy recurrence of the existing vitiligo treatment, and especially the condition of the middle-aged and elderly patients is not adapted, and provides a traditional Chinese medicine composition for treating both principal and secondary aspect of disease and being suitable for the middle-aged and elderly vitiligo patients. The Chinese medicinal composition has the effects of regulating viscera, tonifying qi and blood, dredging channels and collaterals, stimulating local melanin generation, improving local microcirculation, and realizing rapid and long-term stable curative effects and difficult recurrence. In order to achieve the above purpose, the invention adopts the following technical scheme: The traditional Chinese medicine for treating the vitiligo comprises, by weight, 10-20 parts of astragalus membranaceus, 8-16 parts of codonopsis pilosula, 8-16 parts of bighead atractylodes rhizome, 15-25 parts of glabrous greenbrier rhizome, 10-20 parts of Chinese yam, 10-20 parts of fructus psoraleae, 8-16 parts of Chinese angelica, 10-20 parts of cornu bubali, 8-16 parts of dogwood, 10-20 parts of radix salviae miltiorrhizae, 8-16 parts of red paeony root, 6-14 parts of safflower, 6-14 parts of ligusticum wallichii, 6-14 parts of peach kernel, 10-20 parts of polygonum multiflorum, 10-20 parts of eclipta alba, 8-16 parts of white mulberry root-bark, 6-14 parts of divaricate saposhnikovia root, 6-14 parts of radix bupleuri, 6-14 parts of radix scutellariae, 6-14 parts of radix curcumae, 6-14 parts of fingered citron, 6-14 parts of nutgrass galingale rhizome, 3-9 parts of gentian, 10-20 parts of fried white paeony root, 10-20 parts of white atractylodes rhizome, 6-14 parts of fructus tribuli, 6-14 parts of cape jasmine, 6-14 parts of radix angelicae and 3-9 parts of rhizoma typhi. Efficacy and therapeutic mechanism of oral administration 1. Core efficacy The Chinese medicinal composition has the effects of benefiting qi, nourishing blood, tonifying liver and kidney, promoting blood circulation, removing blood stasis, soothing liver, re