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CN-122005741-A - Traditional Chinese medicine composition for treating pulmonary nodules as well as preparation and application thereof

CN122005741ACN 122005741 ACN122005741 ACN 122005741ACN-122005741-A

Abstract

The invention provides a traditional Chinese medicine composition for treating pulmonary nodules, a preparation and application thereof, and relates to the field of traditional Chinese medicines. The invention relates to a traditional Chinese medicine composition for treating pulmonary nodules, which comprises the following raw materials, by weight, 8-12 parts of radix bupleuri, 8-12 parts of cassia twig, 8-12 parts of ginseng, 8-12 parts of radix scutellariae, 8-12 parts of pinellia ternate, 13-18 parts of white paeony root, 8-12 parts of liquorice, 8-12 parts of ginger, 8-12 parts of jujube, 8-12 parts of rhizoma sparganii, 13-18 parts of rhizoma curcumae, 25-35 parts of spina gleditsiae, 17-23 parts of fritillaria cirrhosa, 25-35 parts of coix seed and 13-18 parts of stiff silkworm. In the formula, bupleurum and cassia twig are monarch drugs, baical skullcap root and white paeony root are ministerial drugs, spina gleditsiae, stiff silkworm and thunberg fritillary bulb are ministerial drugs, phlegm eliminating and resolving power is enhanced by matching pinellia tuber, common burreed rhizome and curcuma zedoary are used for activating blood and dissolving stasis, coix seed is used for strengthening spleen and removing pus, ginseng, chinese date and ginger are used as assistants, middle-jiao and dampness are resolved, spleen and stomach are tonified, the transportation and transformation functions are enhanced, spleen and stomach are tonified, the generation of phlegm dampness is reduced from the source after the fixation and protection, liquorice is used for guiding, the medicines are blended, and the medicines are synergized, so that the curative effect of treating lung nodules is remarkable.

Inventors

  • XU LINGXUE
  • HE LIQING
  • MO GUOYAN
  • YANG KUN
  • DONG WEI
  • Yun Yanna
  • YIN TIAN

Assignees

  • 湖北中医药大学

Dates

Publication Date
20260512
Application Date
20260202

Claims (10)

  1. 1. The traditional Chinese medicine composition for treating lung nodules is characterized by comprising, by weight, 8-12 parts of radix bupleuri, 8-12 parts of cassia twig, 8-12 parts of ginseng, 8-12 parts of radix scutellariae, 8-12 parts of pinellia ternate, 13-18 parts of white paeony root, 8-12 parts of liquorice, 8-12 parts of ginger, 8-12 parts of Chinese date, 8-12 parts of rhizoma sparganii, 13-18 parts of rhizoma curcumae, 25-35 parts of spina gleditsiae, 17-23 parts of fritillaria cirrhosa, 25-35 parts of coix seed and 13-18 parts of stiff silkworm.
  2. 2. The traditional Chinese medicine composition for treating pulmonary nodules according to claim 1, wherein the traditional Chinese medicine composition is characterized by comprising the following raw materials, by weight, 10 parts of radix bupleuri, 10 parts of cassia twig, 10 parts of ginseng, 10-12 parts of radix scutellariae, 10 parts of pinellia ternate, 15 parts of white paeony root, 10 parts of liquorice, 10 parts of ginger, 10 parts of jujube, 10 parts of rhizoma sparganii, 15 parts of rhizoma curcumae, 30 parts of spina gleditsiae, 20 parts of fritillaria, 30 parts of semen coicis and 15 parts of stiff silkworm.
  3. 3. The traditional Chinese medicine composition for treating pulmonary nodules according to claim 1, further comprising dragon bone and oyster, wherein the traditional Chinese medicine composition comprises, by weight, 8-12 parts of bupleurum, 8-12 parts of cassia twig, 8-12 parts of ginseng, 8-12 parts of baikal skullcap root, 8-12 parts of pinellia ternate, 13-18 parts of white peony root, 8-12 parts of liquorice, 8-12 parts of ginger, 8-12 parts of Chinese date, 8-12 parts of rhizoma sparganii, 13-18 parts of curcuma zedoary, 25-35 parts of spina gleditsiae, 17-23 parts of fritillaria cirrhosa, 25-35 parts of coix seed, 13-18 parts of stiff silkworm, 13-18 parts of dragon bone and 13-18 parts of oyster.
  4. 4. The traditional Chinese medicine composition for treating pulmonary nodules according to claim 1, further comprising caulis Perillae, wherein the composition comprises, by weight, 8-12 parts of radix bupleuri, 8-12 parts of cassia twig, 8-12 parts of ginseng, 8-12 parts of radix scutellariae, 8-12 parts of pinellia ternate, 13-18 parts of radix paeoniae alba, 8-12 parts of liquorice, 8-12 parts of ginger, 8-12 parts of Chinese date, 8-12 parts of rhizoma sparganii, 13-18 parts of rhizoma curcumae, 25-35 parts of spina gleditsiae, 17-23 parts of fritillaria cirrhosa, 25-35 parts of semen coicis, 13-18 parts of stiff silkworm and 13-18 parts of caulis perillae.
  5. 5. The traditional Chinese medicine composition for treating pulmonary nodules according to any one of claims 1 to 4, wherein the fritillary bulb is fritillary bulb.
  6. 6. The traditional Chinese medicine composition for treating pulmonary nodules according to any one of claims 1 to 4, wherein the pinellia ternate is purified pinellia ternate.
  7. 7. A Chinese medicinal preparation for treating pulmonary nodules, which is prepared from the Chinese medicinal composition according to any one of claims 1-4.
  8. 8. A traditional Chinese medicine decoction for treating pulmonary nodules, which is characterized by being prepared from the traditional Chinese medicine composition according to any one of claims 1-4.
  9. 9. Use of a Chinese medicinal composition according to any one of claims 1 to 4 for the preparation of a medicament for the treatment of pulmonary nodules.
  10. 10. The use of the Chinese medicinal composition according to any one of claims 1-4 in the preparation of a medicament for treating lung nodules with syndrome differentiation of phlegm and blood stasis.

Description

Traditional Chinese medicine composition for treating pulmonary nodules as well as preparation and application thereof Technical Field The invention relates to the field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating pulmonary nodules, a preparation and application thereof. Background Lung nodules refer to solid or sub-solid shadows found in chest imaging with a major dimension of 3cm or less. In recent years, with the continuous expansion of CT in clinical purposes and the application of lung cancer screening and the improvement of high-resolution cross-sectional imaging examination technology, the detection rate of lung nodules is remarkably increased. There are studies showing that the incidence of foreign lung nodules is about 30%. The in-country flow regulation reveals that the detection rate of lung nodules in China is 27% -45.8%. Traditional medicine considers that the etiology of the disease is classified into exogenous disease and internal injury, and pathogenesis is considered as the deficiency and excess of the root. Wherein the deficiency is mainly caused by deficiency of lung, spleen and kidney, and the excess of pathogenic factors is considered as the factors of qi depression, phlegm dampness, blood stasis, toxic and cancerous toxin. The treatment principle of the disease is to strengthen body resistance and eliminate pathogenic factors, treat both principal and secondary aspect of disease. However, the current research is focused on single pathological products or single viscera dysfunction, and a diagnosis and treatment idea capable of comprehensively integrating multiple viscera and links is not available. The five zang organs of the Su Mi (questions of the plain) are communicated, the movement is all the second time. "the disease is not limited to a single viscera, but is related to other viscera. Therefore, if the lung nodule is treated without the whole thinking, the accuracy of the diagnosis and treatment and the improvement of the treatment effect are limited to a great extent. The formation and development of lung nodules are considered to be the occurrence of lung sarcoidosis caused by the common dysfunctions of liver qi failure, lung qi failure, disharmony between ying and wei, triple energizer failure and other systems, rather than the simple local pathological changes of isolated lung. Therefore, the research and development of the traditional Chinese medicine composition with strong targeting, obvious curative effect and high safety has important clinical significance and application value for effectively interfering the progress of lung nodules, reducing the risk of malignant transformation and improving the life quality of patients. Disclosure of Invention In view of the above, the invention provides a traditional Chinese medicine composition for treating pulmonary nodules, a preparation and application thereof, and the traditional Chinese medicine composition has the advantages of strong targeting, remarkable curative effect and high safety. The technical scheme is that the traditional Chinese medicine composition for treating pulmonary nodules is realized by the following raw materials, by weight, 8-12 parts of radix bupleuri, 8-12 parts of cassia twig, 8-12 parts of ginseng, 8-12 parts of radix scutellariae, 8-12 parts of pinellia ternate, 13-18 parts of radix paeoniae alba, 8-12 parts of liquorice, 8-12 parts of ginger, 8-12 parts of Chinese date, 8-12 parts of rhizoma sparganii, 13-18 parts of rhizoma curcumae, 25-35 parts of spina gleditsiae, 17-23 parts of fritillaria cirrhosa, 25-35 parts of semen coicis and 13-18 parts of stiff silkworm. Preferably, the traditional Chinese medicine composition for treating pulmonary nodules comprises the following raw materials, by weight, 10 parts of radix bupleuri, 10 parts of cassia twig, 10 parts of ginseng, 10-12 parts of radix scutellariae, 10 parts of pinellia ternate, 15 parts of white paeony root, 10 parts of liquorice, 10 parts of ginger, 10 parts of Chinese date, 10 parts of rhizoma sparganii, 15 parts of rhizoma curcumae, 30 parts of spina gleditsiae, 20 parts of fritillaria cirrhosa, 30 parts of semen coicis and 15 parts of stiff silkworm. Further, the traditional Chinese medicine composition for treating pulmonary nodules also comprises 8-12 parts of bupleurum, 8-12 parts of cassia twig, 8-12 parts of ginseng, 8-12 parts of baikal skullcap root, 8-12 parts of pinellia tuber, 13-18 parts of white peony root, 8-12 parts of liquorice, 8-12 parts of ginger, 8-12 parts of Chinese date, 8-12 parts of rhizoma sparganii, 13-18 parts of rhizoma zedoariae, 25-35 parts of spina gleditsiae, 17-23 parts of fritillaria, 25-35 parts of coix seed, 13-18 parts of stiff silkworm, 13-18 parts of dragon bone and 13-18 parts of oyster. Preferably, the traditional Chinese medicine composition for treating pulmonary nodules also contains dragon bone and oyster, and comprise