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CN-122006096-A - Multi-dimensional electronic regulation and control microneedle injection medicine introduction system

CN122006096ACN 122006096 ACN122006096 ACN 122006096ACN-122006096-A

Abstract

The invention provides a multidimensional electronic regulation and control microneedle injection medicine introduction system, and belongs to the technical field of medical appliances. The system comprises a shell, a user interaction module, a control and drive module, a drive execution module and a microneedle module integrated with an adjusting and protecting device. The user interaction module realizes multi-parameter cooperative setting and real-time display of injection pressure, dosage and speed through the display screen and the control keys, the control and drive module generates a regulation and control instruction according to the set parameters, the drive execution module precisely controls the liquid medicine to be conveyed according to the instruction, and the regulation and protection device of the microneedle module can control the penetration depth of the microneedle and provide protection when the microneedle is not in use. The invention realizes multidimensional, quantifiable and self-adaptive accurate regulation and control of the drug introduction process through electronic integrated control, effectively improves the safety, the effectiveness and the operation convenience of injection, and is suitable for various administration scenes such as clinic, families and the like.

Inventors

  • ZHA TIANJIAN
  • LIU YAN
  • ZHANG JIAN
  • CAO QIANG
  • CHEN HAIYAN

Assignees

  • 新疆维吾尔自治区人民医院

Dates

Publication Date
20260512
Application Date
20260129

Claims (8)

  1. 1. A multi-dimensional electronically controlled microneedle injection drug delivery system comprising: A housing; The user interaction module is arranged on the shell and comprises a display screen for displaying operation information and control keys for inputting control instructions; A microneedle module at least partially protruding from the housing, comprising: A microneedle; An adjustment protection device, the microneedle being at least partially disposed within the adjustment protection device, the adjustment protection device being configured to be capable of adjusting a penetration depth of the microneedle and/or providing protection to the microneedle; the control and drive module is accommodated in the shell, is electrically connected with the user interaction module and is used for generating a drive signal according to parameters set by the control key, and the parameters at least comprise injection pressure, injection dosage and injection speed; And the driving execution module is electrically connected with the control and driving module and the micro needle, and is used for receiving the driving signal and controlling the micro needle to execute the medicine injection operation based on the driving signal.
  2. 2. The multi-dimensional electronically controlled microneedle injection drug delivery system of claim 1, wherein the regulatory protection device comprises: the protection sleeve is arranged at the front end of the shell in a telescopic way, and the micro needle is positioned in the protection sleeve; and the driving mechanism is connected with the control and driving module and is used for driving the protection sleeve to stretch and retract along the axial direction of the protection sleeve so as to retract the micro-needle into the sleeve before injection, and the micro-needle is exposed and the penetration depth of the micro-needle is controlled during injection.
  3. 3. The multi-dimensional electronically controlled microneedle injection drug delivery system of claim 1, wherein the user interaction module further comprises: the parameter selection unit is used for providing a parameter selection interface on the display screen so as to set or switch the type of the parameter to be adjusted; And the parameter adjusting unit is associated with the control key and is used for continuously or stepwise adjusting the value of the selected parameter by operating the control key after the type of the selected parameter is selected.
  4. 4. The multi-dimensional electronically controlled microneedle injection drug delivery system of claim 1, wherein the drive execution module comprises: A micropump connected to the fluid channel of the microneedle; A pressure sensor for monitoring injection pressure of the microneedle tips in real time; The control and drive module is configured to receive a feedback signal from the pressure sensor and dynamically adjust the output of the micropump in a closed loop control manner to bring the actual injection pressure into agreement with the set injection pressure.
  5. 5. The multi-dimensional electronically controlled microneedle injection drug delivery system of claim 1, further comprising: A medicine storage unit detachably connected to the housing for accommodating a medicine to be injected; a connecting conduit for communicating the drug storage unit with the fluid channel of the microneedle.
  6. 6. The multi-dimensional electronically controlled microneedle injection drug delivery system of claim 1, wherein the control and drive module further comprises: An injection mode selection unit configured to provide a plurality of preset injection modes, each mode associated with a set of preset pressure, dose and speed parameter combinations; The user interaction module is configured to allow a user to select the injection mode via the control key.
  7. 7. The multi-dimensional electronically controlled microneedle injection drug delivery system of claim 1, wherein the microneedle is a microneedle array comprising a plurality of microneedles.
  8. 8. The multi-dimensional electronically controlled microneedle injection drug delivery system of claim 1, wherein the control and drive module further comprises a memory unit for recording and storing parameter settings, execution time, and user identification information for each injection operation.

Description

Multi-dimensional electronic regulation and control microneedle injection medicine introduction system Technical Field The invention relates to the field of medical instruments, in particular to a multidimensional electronic regulation and control microneedle injection medicine introduction system. Background Transdermal drug delivery is an important drug delivery mode, and compared with oral administration or intravenous injection, the transdermal drug delivery can avoid first pass effect, improve local drug concentration and reduce systemic side effects. However, the stratum corneum of human skin constitutes a strong physical and chemical barrier, severely limiting the transdermal absorption of most drug molecules, especially macromolecular drugs (e.g., proteins, polypeptides, nucleic acids, etc.). While capable of delivering a variety of drugs, conventional subcutaneous injections use sharp injection needles, which can give pain, fear to the patient, and require specialized training for operation, are inconvenient to use in home or long-term self-administration settings. The microneedle technology is used as an emerging percutaneous administration means, and by manufacturing an array of needle-like structures with a micrometer scale, the stratum corneum on the outermost layer of the skin can be pierced, and a micrometer-scale channel is formed above the dermis layer, so that drug permeation is remarkably promoted, and painless or micro-pain administration can be realized due to the fact that the needle body is short (nerve endings deep in the dermis layer are not touched generally). However, there are still a number of limitations to existing microneedle systems, particularly microneedle injection systems for active drug delivery: The injection parameters are single and rough in control, and many active microneedle systems can only realize a simple injection/stop function or can only adjust a single parameter (such as injection speed), so that the key parameters such as injection pressure, injection rate, injection dosage and the like are difficult to carry out multi-dimensional fine cooperative regulation and control according to the physicochemical properties (such as viscosity) of the medicament, the tissue characteristics of a treatment part and the individual difference of patients. This "one-shot" injection pattern may result in uneven distribution of the drug within the tissue, localized over-pressure causing tissue damage, or poor injection efficiency. The existing system is mainly controlled in an open loop, and can not dynamically adjust output according to real-time feedback (such as tissue backpressure) in the injection process, so that the system is poor in adaptability. While facing soft tissue of varying skin thickness, density, a fixed injection procedure may not guarantee accurate drug introduction to the target depth and area. Safety and ease of use are to be enhanced by exposing part of the system's microneedles to the outside, with the risk of accidental puncture. Meanwhile, the operation interface is often complex, parameter setting is not visual, and popularization and application of the device in non-professional medical environments are limited. In order to solve the above problems, the applicant proposes a multi-dimensional electronically controlled microneedle injection drug delivery system. Disclosure of Invention The invention aims to provide a multidimensional electronic regulation and control microneedle injection medicine introducing system so as to solve the problems in the prior art. In order to achieve the purpose, the invention provides the technical scheme that the multi-dimensional electronic regulation and control microneedle injection medicine introducing system comprises: A housing; The user interaction module is arranged on the shell and comprises a display screen for displaying operation information and control keys for inputting control instructions; A microneedle module at least partially protruding from the housing, comprising: A microneedle; An adjustment protection device, the microneedle being at least partially disposed within the adjustment protection device, the adjustment protection device being configured to be capable of adjusting a penetration depth of the microneedle and/or providing protection to the microneedle; the control and drive module is accommodated in the shell, is electrically connected with the user interaction module and is used for generating a drive signal according to parameters set by the control key, and the parameters at least comprise injection pressure, injection dosage and injection speed; And the driving execution module is electrically connected with the control and driving module and the micro needle, and is used for receiving the driving signal and controlling the micro needle to execute the medicine injection operation based on the driving signal. Optionally, the adjustment protection device includes: the protection sleeve